Research Output

2020

Advances in cytomegalovirus (CMV) biology and its relationship to health, diseases, and aging

Nikolich-Žugich, J., Čicin-Šain, L., Collins-McMillen, D., Jackson, S., Oxenius, A., Sinclair, J., Snyder, C., Wills, M. & Lemmermann, N., Apr 1 2020, In : GeroScience. 42, 2, p. 495-504 10 p.

Research output: Contribution to journalReview article

Early events in coccidioidomycosis

Donovan, F. M., Shubitz, L., Powell, D., Orbach, M., Frelinger, J. & Galgiani, J. N., Jan 2020, In : Clinical Microbiology Reviews. 33, 1, e00112-19.

Research output: Contribution to journalArticle

1 Scopus citations

Erratum: Human cytomegalovirus UL135 interacts with host adaptor proteins to regulate epidermal growth factor receptor and reactivation from latency" (Journal of Virology (2018) 92:20 (e00919-18) DOI: 10.1128/JVI.00919-1)

Rak, M. A., Buehler, J., Zeltzer, S., Reitsma, J., Molina, B., Terhune, S. & Goodrum, F., Mar 1 2020, In : Journal of virology. 94, 7, e00919-18.

Research output: Contribution to journalComment/debate

Open Access

Human cytomegalovirus infection suppresses cd34+ progenitor cell engraftment in humanized mice

Crawford, L. B., Tempel, R., Streblow, D. N., Yurochko, A. D., Goodrum, F. D., Nelson, J. A. & Caposio, P., Apr 2020, In : Microorganisms. 8, 4, 525.

Research output: Contribution to journalArticle

Open Access

Immunological mechanisms in poststroke dementia

Doyle, K. P. & Buckwalter, M. S., Feb 1 2020, In : Current opinion in neurology. 33, 1, p. 30-36 7 p.

Research output: Contribution to journalArticle

SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes

Nikolich-Zugich, J., Knox, K. S., Rios, C. T., Natt, B., Bhattacharya, D. & Fain, M. J., Apr 1 2020, In : GeroScience. 42, 2, p. 505-514 10 p.

Research output: Contribution to journalReview article

Open Access
2019

Alternative promoters drive human cytomegalovirus reactivation from latency

Collins-McMillen, D., Rak, M., Buehler, J. C., Igarashi-Hayes, S., Kamil, J. P., Moorman, N. J. & Goodrum, F., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17492-17497 6 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

A Natural Mouse Model for Neisseria Persistent Colonization

Rhodes, K., Ma, M. & So, M. M., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 403-412 10 p. (Methods in Molecular Biology; vol. 1997).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Commensal Neisseria Kill Neisseria gonorrhoeae through a DNA-Dependent Mechanism

Kim, W. J., Higashi, D., Goytia, M., Rendón, M. A., Pilligua-Lucas, M., Bronnimann, M., McLean, J. A., Duncan, J., Trees, D., Jerse, A. E. & So, M. M., Aug 14 2019, In : Cell Host and Microbe. 26, 2, p. 228-239.e8

Research output: Contribution to journalArticle

8 Scopus citations
Open Access

Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency

Kim, C., Jadhav, R. R., Gustafson, C. E., Smithey, M. J., Hirsch, A. J., Uhrlaub, J. L., Hildebrand, W. H., Nikolich-Žugich, J., Weyand, C. M. & Goronzy, J. J., Nov 19 2019, In : Cell Reports. 29, 8, p. 2202-2216.e5

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Dilated Blood and Lymphatic Microvessels, Angiogenesis, Increased Macrophages, and Adipocyte Hypertrophy in Lipedema Thigh Skin and Fat Tissue

Al-Ghadban, S., Cromer, W., Allen, M., Ussery, C., Badowski, M., Harris, D. & Herbst, K. L., Jan 1 2019, In : Journal of Obesity. 2019, 8747461.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Do cytomegalovirus-specific memory T cells interfere with new immune responses in lymphoid tissues?

Jergović, M., Uhrlaub, J. L., Contreras, N. A. & Nikolich-Zugich, J., Apr 15 2019, In : GeroScience. 41, 2, p. 155-163 9 p.

Research output: Contribution to journalArticle

Frailty as a prognostic factor for the critically ill older adult trauma patients

Hamidi, M., Zeeshan, M., Leon-Risemberg, V., Nikolich-Zugich, J., Hanna, K., Kulvatunyou, N., Saljuqi, A. T., Fain, M. J. & Joseph, B. A., Jan 1 2019, In : American journal of surgery.

Research output: Contribution to journalArticle

4 Scopus citations

Glutathione contributes to efficient post-Golgi trafficking of incoming HPV16 genome

Li, S., Bronnimann, M. P., Williams, S. J. & Campos, S. K., Jan 1 2019, In : PloS one. 14, 11, e0225496.

Research output: Contribution to journalArticle

Open Access

HCMV miR-US22 down-regulation of EGR-1 regulates CD34+ hematopoietic progenitor cell proliferation and viral reactivation

Mikell, I., Crawford, L. B., Hancock, M. H., Mitchell, J., Buehler, J., Goodrum, F. & Nelson, J. A., Jan 1 2019, In : PLoS pathogens. 15, 11, e1007854.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
Open Access
2 Scopus citations

Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency

Buehler, J., Carpenter, E., Zeltzer, S., Igarashi, S., Rak, M., Mikell, I., Nelson, J. A. & Goodrum, F., Jan 1 2019, In : PLoS pathogens. 15, 11, e1008037.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Human rDNA copy number is unstable in metastatic breast cancers

Valori, V., Tus, K., Laukaitis, C., Harris, D. T., LeBeau, L. & Maggert, K. A., Jan 1 2019, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journalArticle

2 Scopus citations

Impact of CMV upon immune aging: facts and fiction

Jergović, M., Contreras, N. A. & Nikolich-Zugich, J., Jan 1 2019, In : Medical Microbiology and Immunology.

Research output: Contribution to journalReview article

6 Scopus citations

Impact of gut microbiota on gut-distal autoimmunity: a focus on T cells

Sprouse, M. L., Bates, N. A., Felix, K. M. & Wu, H. J. J., Apr 2019, In : Immunology. 156, 4, p. 305-318 14 p.

Research output: Contribution to journalReview article

3 Scopus citations

Kissing Bugs Harboring Trypanosoma cruzi, Frequently Bite Residents of the US Southwest But Do Not Cause Chagas Disease

Behrens-Bradley, N., Smith, S., Beatty, N. L., Love, M., Ahmad, N. ., Dorn, P. L., Schmidt, J. O. & Klotz, S. A., Jan 1 2019, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

Life-long control of cytomegalovirus (CMV) by t resident memory cells in the adipose tissue results in inflammation and hyperglycemia

Contreras, N. A., Sitnik, K. M., Jeftic, I., Coplen, C. P., Čičin-šain, L. & Nikolich-žugich, J., Jun 2019, In : PLoS pathogens. 15, 6, e1007890.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates

Thompson, H. L., Smithey, M. J., Uhrlaub, J. L., Jeftić, I., Jergović, M., White, S. E., Currier, N., Lang, A. M., Okoye, A., Park, B., Picker, L. J., Surh, C. D. & Nikolich-Žugich, J., Feb 1 2019, In : Aging Cell. 18, 1, e12865.

Research output: Contribution to journalArticle

8 Scopus citations

Menopause and foxp3 treg cell depletion eliminate female protection against t cell-mediated angiotensin ii hypertension

Pollow, D. P., Uhlorn, J. A., Sylvester, M. A., Romero-Aleshire, M. J., Uhrlaub, J. L., Lindsey, M. L., Nikolich-Zugich, J. & Brooks, H. L., Aug 1 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 317, 2, p. H415-H423

Research output: Contribution to journalArticle

3 Scopus citations
Open Access
1 Scopus citations

Neisseria gonorrhoeae evades autophagic killing by downregulating CD46-cyt1 and remodeling lysosomes

Kim, W. J., Mai, A., Weyand, N. J., Rendón, M. A., Van Doorslaer, K. & So, M., Feb 2019, In : PLoS pathogens. 15, 2, e1007495.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

P2Rx7 deletion in T cells promotes autoimmune arthritis by unleashing the TFH cell response

Felix, K. M., Teng, F., Bates, N. A., Ma, H., Jaimez, I. A., Sleiman, K. C., Tran, N. L. & Joyce Wu, H. J., Jan 1 2019, In : Frontiers in immunology. 10, MAR, 411.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Perinatal tissue-derived stem cells: Sources and applications

Harris, D. T., Jan 1 2019, Encyclopedia of Tissue Engineering and Regenerative Medicine. Elsevier, Vol. 1-3. p. 35-43 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rapid detection of human blood in triatomines (kissing bugs) utilizing a lateral flow immunochromatographic assay - A pilot study

Beatty, N. L., Behrens-Bradley, N., Love, M., McCants, F., Smith, S., Schmidt, J. O., Hamer, S. A., Dorn, P. L., Ahmad, N. & Klotz, S. A., Jan 1 2019, In : Memorias do Instituto Oswaldo Cruz. 114, p. e190047

Research output: Contribution to journalArticle

Open Access

RpoN and the Nps and Npa two-component regulatory system control pilE transcription in commensal Neisseria

Rendón, M. A., Lona, B., Ma, M. & So, M., May 2019, In : MicrobiologyOpen. 8, 5, e00713.

Research output: Contribution to journalArticle

1 Scopus citations

The acute inflammatory response after trauma is heightened by frailty: A prospective evaluation of inflammatory and endocrine system alterations in frailty

Palmer, J., Pandit, V., Zeeshan, M., Kulvatunyou, N., Hamidi, M., Hanna, K., Fain, M., Nikolich-Zugich, J., Zakaria, E. R. & Joseph, B., Jul 1 2019, In : Journal of Trauma and Acute Care Surgery. 87, 1, p. 54-60 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Tribal warfare: Commensal Neisseria kill pathogen Neisseria gonorrhoeae using its DNA

So, M. & Rendón, M. A., Jan 1 2019, In : Microbial Cell. 6, 12, p. 544-546 3 p.

Research output: Contribution to journalShort survey

Open Access

Universal Principled Review: A Community-Driven Method to Improve Peer Review

The Future Immunology Consortium, Dec 12 2019, In : Cell. 179, 7, p. 1441-1445 5 p.

Research output: Contribution to journalComment/debate

Open Access

What will Become of the Taxpayer Investment in Public Cord Blood Stem Cell Banking?

Harris, D. T. & Israel, S., Jan 1 2019, In : Current stem cell research & therapy. 14, 4, p. 367-372 6 p.

Research output: Contribution to journalArticle

2018

Adaptive immunity to Francisella tularensis and considerations for vaccine development

Roberts, L. M., Powell, D. A. & Frelinger, J. A., Apr 6 2018, In : Frontiers in cellular and infection microbiology. 8, APR, 115.

Research output: Contribution to journalReview article

6 Scopus citations

A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice

Deshpande, N. R., Uhrlaub, J. L., Way, S. S., Nikolich-Žugich, J. & Kuhns, M. S., Jun 2018, In : PloS one. 13, 6, e0198354.

Research output: Contribution to journalArticle

Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia

Nguyen, T. V. V., Hayes, M., Zbesko, J. C., Frye, J. B., Congrove, N. R., Belichenko, N. P., Mckay, B. S., Longo, F. M. & Doyle, K., Sep 24 2018, In : Acta neuropathologica communications. 6, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

A natural mouse model for Neisseria colonization

Ma, M., Powell, D. A., Weyand, N. J., Rhodes, K. A., Rendón, M. A., Frelinger, J. A. & So, M., May 1 2018, In : Infection and Immunity. 86, 5, e00839-17.

Research output: Contribution to journalArticle

5 Scopus citations

A single-cell approach to the elusive latent human cytomegalovirus transcriptome

Goodrum, F. & McWeeney, S., May 1 2018, In : mBio. 9, 3, e01001-18.

Research output: Contribution to journalArticle

2 Scopus citations

Biobanking and omics

Harris, D. T., Jan 1 2018, (Accepted/In press) In : Frontiers in Biology.

Research output: Contribution to journalArticle

Bonds Voyage! A Dissociative Model of TCR-CD3 Triggering Is Proposed

Lichauco, K., Lee, M. S. & Kuhns, M. S., Jan 1 2018, (Accepted/In press) In : Immunity.

Research output: Contribution to journalArticle

Calorie restriction induces reversible lymphopenia and lymphoid organ atrophy due to cell redistribution

Contreras, N. A., Fontana, L., Tosti, V. & Nikolich-Zugich, J., May 26 2018, (Accepted/In press) In : GeroScience. p. 1-13 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Comparison of synthetic media designed for expansion of adipose-derived mesenchymal stromal cells

Lensch, M., Muise, A., White, L., Badowski, M. & Harris, D. T., Jun 1 2018, In : Biomedicines. 6, 2, 54.

Research output: Contribution to journalArticle

2 Scopus citations

Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low PAX5

Nipper, A. J., Smithey, M. J., Shah, R. C., Canaday, D. H. & Landay, A. L., Jan 1 2018, (Accepted/In press) In : Clinical Immunology.

Research output: Contribution to journalArticle

6 Scopus citations

Farewell Stan Stanley Falkow: 1934–2018

Cabello, F. C., Cohen, S. N., Curtiss, R., Dougan, G., van Embden, J., Finlay, B. B., Heffron, F., Helinski, D., Hull, R., Hull, S., Isberg, R., Kopecko, D. J., Levy, S., Mekalanos, J., Ortiz, J. M., Rappuoli, R., Roberts, M. C., So, M. M. & Timmis, K. N., Jan 1 2018, (Accepted/In press) In : Environmental Microbiology.

Research output: Contribution to journalArticle

Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts

Zbesko, J. C., Nguyen, T. V. V., Yang, T., Frye, J. B., Hussain, O., Hayes, M., Chung, A., Day, W. A., Stepanovic, K., Krumberger, M., Mona, J., Longo, F. M. & Doyle, K., Apr 1 2018, In : Neurobiology of Disease. 112, p. 63-78 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Gut microbiota contributes to resistance against Pneumococcal Pneumonia in immunodeficient Ragl Mice

Felix, K. M., Jaimez, I. A., Nguyen, T. V. V., Ma, H., Raslan, W. A., Klinger, C. N., Doyle, K. P. & Wu, H. J. J., Apr 18 2018, In : Frontiers in Cellular and Infection Microbiology. 8, APR, 118.

Research output: Contribution to journalArticle

5 Scopus citations