Research Output

Article

A20-Deficient Mast Cells Exacerbate Inflammatory Responses In Vivo

Heger, K., Fierens, K., Vahl, J. C., Aszodi, A., Peschke, K., Schenten, D., Hammad, H., Beyaert, R., Saur, D., van Loo, G., Roers, A., Lambrecht, B. N., Kool, M. & Schmidt-Supprian, M., Jan 1 2014, In : PLoS biology. 12, 1, e1001762.

Research output: Contribution to journalArticle

42 Scopus citations

A broadly applicable approach to T cell epitope identification: Application to improving tumor associated epitopes and identifying epitopes in complex pathogens

Valentino, M. D., Abdul-Alim, C. S., Maben, Z. J., Skrombolas, D., Hensley, L. L., Kawula, T. H., Dziejman, M., Lord, E. M., Frelinger, J. A. & Frelinger, J. G., Oct 28 2011, In : Journal of Immunological Methods. 373, 1-2, p. 111-126 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

A central region in the minor capsid protein of papillomaviruses facilitates viral genome tethering and membrane penetration for mitotic nuclear entry

Aydin, I., Villalonga-Planells, R., Greune, L., Bronnimann, M. P., Calton, C. M., Becker, M., Lai, K. Y., Campos, S. K., Schmidt, M. A. & Schelhaas, M., May 2017, In : PLoS pathogens. 13, 5, e1006308.

Research output: Contribution to journalArticle

20 Scopus citations

A cluster of mutations in HLA-A2 α2 helix abolishes peptide recognition by T cells

Moots, R. J., Matsui, M., Pazmany, L., McMichael, A. J. & Frelinger, J. A., Sep 1 1991, In : Immunogenetics. 34, 3, p. 141-148 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

A Coccidioides posadasii CPS1 deletion mutant is avirulent and protects mice from lethal infection

Narra, H. P., Shubitz, L., Mandel, M. A., Trinh, H. T., Griffin, K., Buntzman, A. S., Frelinger, J. A., Galgiani, J. N. & Orbach, M. J., 2016, In : Infection and Immunity. 84, 10, p. 3007-3016 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

A cross‐species functional interaction between the murine major histocompatibility complex class I α3 domain and human CD8 revealed by peptide‐specific cytotoxic T lymphocytes

Moots, R. J., Samberg, N. L., Pazmany, L., Frelinger, J. A., McMichael, A. J. & Stauss, H. J., Jun 1992, In : European Journal of Immunology. 22, 6, p. 1643-1646 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Acute Neonatal Infections 'Lock-In' a Suboptimal CD8+ T Cell Repertoire with Impaired Recall Responses

Rudd, B. D., Venturi, V., Smith, N. L., Nzingha, K., Goldberg, E. L., Li, G., Nikolich-Zugich, J. & Davenport, M. P., Sep 1 2013, In : PLoS pathogens. 9, 9, e1003572.

Research output: Contribution to journalArticle

16 Scopus citations

Acute systemic DNA damage in youth does not impair immune defense with aging

Pugh, J. L., Foster, S. A., Sukhina, A. S., Petravic, J., Uhrlaub, J. L., Padilla-Torres, J., Hayashi, T., Nakachi, K., Smithey, M. J. & Nikolich-Žugich, J., Aug 1 2016, In : Aging Cell. 15, 4, p. 686-693 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Adenylate cyclase toxin of Bordetella pertussis: Production, purification, and partial characterization

Leusch, M. S., Paulaitis, S. & Friedman, R. L., Jan 1 1990, In : Infection and Immunity. 58, 11, p. 3621-3626 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice

Deshpande, N. R., Uhrlaub, J. L., Way, S. S., Nikolich-Žugich, J. & Kuhns, M. S., Jun 2018, In : PloS one. 13, 6, e0198354.

Research output: Contribution to journalArticle

15 Scopus citations

A function-associated molecule on rat natural killer cells identified by anti-idiotypic monoclonal antibodies

Evans, D. L., Harris, D. T., Leary, J. & Jaso-Friedmann, L., May 1992, In : Cellular Immunology. 141, 2, p. 293-305 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium

Li, G., Smithey, M. J., Rudd, B. D. & Nikolich-Žugich, J., Dec 1 2012, In : Aging Cell. 11, 6, p. 968-977 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Age-associated increase of low-avidity cytomegalovirus-specific CD8 + T cells that re-express CD45RA

Griffiths, S. J., Riddell, N. E., Masters, J., Libri, V., Henson, S. M., Wertheimer, A., Wallace, D., Sims, S., Rivino, L., Larbi, A., Kemeny, D. M., Nikolich-Zugich, J., Kern, F., Klenerman, P., Emery, V. C. & Akbar, A. N., Jun 1 2013, In : Journal of Immunology. 190, 11, p. 5363-5372 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans

Wertheimer, A. M., Bennett, M. S., Park, B., Uhrlaub, J. L., Martinez, C., Pulko, V., Currier, N. L., Nikolich-Zugich, D., Kaye, J. & Nikolich-Zugich, J., Mar 1 2014, In : Journal of Immunology. 192, 5, p. 2143-2155 13 p.

Research output: Contribution to journalArticle

124 Scopus citations

Allelic diversity at the DLA-88 locus in Golden Retriever and Boxer breeds is limited

Ross, P., Buntzman, A. S., Vincent, B. G., Grover, E. N., Gojanovich, G. S., Collins, E. J., Frelinger, J. A. & Hess, P. R., Aug 1 2012, In : Tissue Antigens. 80, 2, p. 175-183 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Alterations in target cell membrane phospholipids alter T cell but not NK cell killing

Harris, D. T., Jan 1 2013, In : Immunobiology. 218, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alternative promoters drive human cytomegalovirus reactivation from latency

Collins-McMillen, D., Rak, M., Buehler, J. C., Igarashi-Hayes, S., Kamil, J. P., Moorman, N. J. & Goodrum, F., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17492-17497 6 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Altertoxins with potent anti-HIV activity from Alternaria tenuissima QUE1Se, a fungal endophyte of Quercus emoryi

Bashyal, B. P., Wellensiek, B. P., Ramakrishnan, R., Faeth, S. H., Ahmad, N. & Gunatilaka, A. A. L., Nov 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 21, p. 6112-6116 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia

Nguyen, T. V. V., Hayes, M., Zbesko, J. C., Frye, J. B., Congrove, N. R., Belichenko, N. P., Mckay, B. S., Longo, F. M. & Doyle, K., Sep 24 2018, In : Acta neuropathologica communications. 6, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

A Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ

Lee, M. S., Glassman, C. R., Deshpande, N. R., Badgandi, H. B., Parrish, H. L., Uttamapinant, C., Stawski, P. S., Ting, A. Y. & Kuhns, M. S., Aug 18 2015, In : Immunity. 43, 2, p. 227-239 13 p., 3145.

Research output: Contribution to journalArticle

46 Scopus citations

Analysis of adenovirus infections in synchronized cells.

Ornelles, D. A., Broughton-Shepard, R. N. & Goodrum, F. D., 2007, In : Methods in molecular medicine. 131, p. 83-101 19 p.

Research output: Contribution to journalArticle

3 Scopus citations

Analysis of an evolutionarily-conserved function-associated molecule (FAM) on murine natural killer (NK) cells

Acevedo, A., Kapur, R. & Harris, D. T., Jan 1 1991, In : Developmental and Comparative Immunology. 15, SUPPL. 1, p. S106

Research output: Contribution to journalArticle

Analysis of mutant HLA-A2 molecules: Differential effects on peptide binding and CTL recognition

Tussey, L. G., Matsui, M., Rowland-Jones, S., Warburton, R., Frelinger, J. A. & McMichael, A., Feb 1 1994, In : Journal of Immunology. 152, 3, p. 1213-1221 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Analysis of the alloreactive capacity of human umbilical cord blood: Implications for graft-versus-host disease

Harris, D. T., LoCascio, J. & Besencon, F. J., Nov 19 1994, In : Bone Marrow Transplantation. 14, 4, p. 545-553 9 p.

Research output: Contribution to journalArticle

86 Scopus citations

Analysis of the hairless mouse as a model for the effects of aging on the immune system

Harris, D. T., LoCascio, J., Acevedo, A., Olson, G. B., Bard, J. & Boyse, E. A., Apr 1993, In : Immunology Letters. 36, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

A natural mouse model for Neisseria colonization

Ma, M., Powell, D. A., Weyand, N. J., Rhodes, K. A., Rendón, M. A., Frelinger, J. A. & So, M., May 1 2018, In : Infection and Immunity. 86, 5, e00839-17.

Research output: Contribution to journalArticle

5 Scopus citations

An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle

Li, G., Rak, M., Nguyen, C. C., Umashankar, M., Goodrum, F. D. & Kamil, J. P., Jun 2014, In : Journal of virology. 88, 11, p. 6047-6060 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

An interlaboratory comparison of dosimetry for a multi-institutional radiobiological research project: Observations, problems, solutions and lessons learned

Seed, T. M., Xiao, S., Manley, N., Nikolich-Zugich, J., Pugh, J., Van Den Brink, M., Hirabayashi, Y., Yasutomo, K., Iwama, A., Koyasu, S., Shterev, I., Sempowski, G., Macchiarini, F., Nakachi, K., Kunugi, K. C., Hammer, C. G. & Dewerd, L. A., Feb 1 2016, In : International Journal of Radiation Biology. 92, 2, p. 59-70 12 p.

Research output: Contribution to journalArticle

7 Scopus citations
2 Scopus citations

A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection

Umashankar, M., Petrucelli, A., Cicchini, L., Caposio, P., Kreklywich, C. N., Rak, M., Bughio, F., Goldman, D. C., Hamlin, K. L., Nelson, J. A., Fleming, W. H., Streblow, D. N. & Goodrum, F., Dec 1 2011, In : PLoS pathogens. 7, 12, e1002444.

Research output: Contribution to journalArticle

77 Scopus citations

A novel inducible amplifier expression vector for high and controlled gene expression.

Luo, P., He, X., Tsang, T. C. & Harris, D. T., Feb 2004, In : International journal of molecular medicine. 13, 2, p. 319-325 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

A novel target cell antigen involved in the NK-like lytic activity of antigen-specific cytotoxic T lymphocytes

Harris, D. T., Jaso-Friedmann, L. & Evans, D. L., Sep 1993, In : Immunology Letters. 38, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection

Umashankar, M., Rak, M., Bughio, F., Zagallo, P., Caviness, K. & Goodrum, F. D., Jun 2014, In : Journal of virology. 88, 11, p. 5987-6002 16 p.

Research output: Contribution to journalArticle

25 Scopus citations

Antigen epitope-expressing cytokines for DNA immunization

He, X., Tsang, T. C., Zhang, T., Luo, P. & Harris, D. T., Mar 14 2005, In : Vaccine. 23, 16, p. 1966-1972 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

A self-augmenting gene expression cassette for enhanced and sustained transgene expression in the presence of proinflammatory cytokines

Luo, P., Reed, B. D., Tsang, T. C., Harris, D. T. & Flavell, R. A., Dec 1 2006, In : DNA and Cell Biology. 25, 12, p. 659-667 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

A single-cell approach to the elusive latent human cytomegalovirus transcriptome

Goodrum, F. & McWeeney, S., May 1 2018, In : mBio. 9, 3, e01001-18.

Research output: Contribution to journalArticle

2 Scopus citations

A species-conserved NK cell antigen receptor is a novel vimentin-like molecule

Harris, D. T., Kapur, R., Frye, C., Acevedo, A., Camenisch, T., Jaso-Friedmann, L. & Evans, D. L., Jan 1 1992, In : Developmental and Comparative Immunology. 16, 5, p. 395-403 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

A study of the dissemination of Tn1681: a bacterial transposon encoding a heat-stable toxin among enterotoxigenic Escherichia coli isolates.

So, M., Atchison, R., Falkow, S., Moseley, S. & McCarthy, B. J., 1981, In : Cold Spring Harbor symposia on quantitative biology. 45 Pt 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

A transmembrane domain and GxxxG motifs within L2 are essential for papillomavirus infection

Bronnimann, M. P., Chapman, J. A., Park, C. K. & Campos, S. K., Jan 1 2013, In : Journal of virology. 87, 1, p. 464-473 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

A transmembrane domain GGxxG Motif in CD4 contributes to its lck-independent function but does not mediate CD4 dimerization

Parrish, H. L., Glassman, C. R., Keenen, M. M., Deshpande, N. R., Bronnimann, M. P. & Kuhns, M. S., Jul 6 2015, In : PLoS One. 10, 7, e0132333.

Research output: Contribution to journalArticle

5 Scopus citations

Attenuation of the type IV pilus retraction motor influences Neisseria gonorrhoeae social and infection behavior

Hockenberry, A. M., Hutchens, D. M., Agellon, A. & So, M., Jan 1 2016, In : mBio. 7, 6, e01994-16.

Research output: Contribution to journalArticle

9 Scopus citations

Author Correction: Charles D. Surh 1960–2017

Nikolich-Zugich, J., Dec 8 2017, (Accepted/In press) In : Nature Immunology. 1 p.

Research output: Contribution to journalArticle

Bacterial luciferase is naturally destabilized in Mycobacterium tuberculosis and can be used to monitor changes in gene expression

Roberts, E. A., Clark, A. & Friedman, R. L., Feb 1 2005, In : FEMS Microbiology Letters. 243, 1, p. 243-249 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse

Danilo, C. A., Constantopoulos, E., McKee, L. A., Chen, H., Regan, J. A., Lipovka, Y., Lahtinen, S., Stenman, L. K., Nguyen, T. V. V., Doyle, K., Slepian, M. J., Khalpey, Z. I. & Konhilas, J., 2017, In : Beneficial microbes. 8, 2, p. 257-269 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Big Data, Big Opportunities, and Big Challenges

Frelinger, J. A., Nov 1 2015, In : Journal of Investigative Dermatology Symposium Proceedings. 17, 2, p. 33-35 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Biobanking and omics

Harris, D. T., Jan 1 2018, (Accepted/In press) In : Frontiers in Biology.

Research output: Contribution to journalArticle

Biological characterization of HIV type 1 envelope V3 regions from mothers and infants associated with perinatal transmission

Matala, E., Hahn, T., Yedavalli, V. R. K. & Ahmad, N., Dec 1 2001, In : AIDS Research and Human Retroviruses. 17, 18, p. 1725-1735 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

B-lymphocyte-mediated delayed cognitive impairment following stroke

Doyle, K. P., Quach, L. N., Solé, M., Axtell, R. C., Nguyen, T. V. V., Soler-Llavina, G. J., Jurado, S., Han, J., Steinman, L., Longo, F. M., Schneider, J. A., Malenka, R. C. & Buckwalter, M. S., Jan 1 2015, In : Journal of Neuroscience. 35, 5, p. 2133-2145 13 p.

Research output: Contribution to journalArticle

102 Scopus citations