Research Output

2014

Effect of anti-coagulant choice on cord blood processing results

Badowski, M., Shultz, C. & Harris, D. T., 2014, (Accepted/In press) In : Cytotherapy.

Research output: Contribution to journalArticle

Elimination of Pasteurella pneumotropica from a mouse barrier facility by using a modified enrofloxacin treatment regimen

Towne, J. W., Wagner, A. M., Griffin, K. J., Buntzman, A. S., Frelinger, J. A. & Besselsen, D. G., Sep 1 2014, In : Journal of the American Association for Laboratory Animal Science. 53, 5, p. 517-522 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Fusion of HepG2 cells with mesenchymal stem cells increases cancer-associated and malignant properties: An in vivo metastasis model

Li, H., Feng, Z., Tsang, T. C., Tang, T., Jia, X., He, X., Pennington, M. E., Badowski, M. S., Liu, A. K. M., Chen, D., Harris, D. T., Martinez, J. & Meade-Tollin, L. C., Aug 2014, In : Oncology Reports. 32, 2, p. 539-547 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Histone deacetylation critically determines T cell subset radiosensitivity

Pugh, J. L., Sukhina, A. S., SeedG, T. M., Manley, N. R., Sempowski, G. D., Van Den Brink, M. R. M., Smithey, M. J. & Nikolich-Žugich, J., Aug 1 2014, In : Journal of Immunology. 193, 3, p. 1451-1458 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Identification of early interactions between Francisella and the host

Roberts, L. M., Tuladhar, S., Steele, S. P., Riebe, K. J., Chen, C. J., Ian Cumming, R., Seay, S., Frothingham, R., Sempowski, G. D., Kawula, T. H. & Frelinger, J. A., 2014, In : Infection and Immunity. 82, 6, p. 2504-2510 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

IFN-γ, but not IL-17A, is required for survival during secondary pulmonary Francisella tularensis Live Vaccine Stain infection

Roberts, L. M., Davies, J. S., Sempowski, G. D. & Frelinger, J. A., Jun 17 2014, In : Vaccine. 32, 29, p. 3595-3603 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
18 Scopus citations

Long term human reconstitution and immune aging in NOD-Rag (-)-γ chain (-) mice

Harris, D. T. & Badowski, M., Feb 1 2014, In : Immunobiology. 219, 2, p. 131-137 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mixed effects of long-term frozen storage on cord tissue stem cells

Badowski, M., Muise, A. & Harris, D. T., Sep 2014, In : Cytotherapy. 16, 9, p. 1313-1321 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Naïve and memory CD8 T cell pool homeostasis in advanced aging: Impact of age and of antigen-specific responses to cytomegalovirus

Vescovini, R., Fagnoni, F. F., Telera, A. R., Bucci, L., Pedrazzoni, M., Magalini, F., Stella, A., Pasin, F., Medici, M. C., Calderaro, A., Volpi, R., Monti, D., Franceschi, C., Nikolich-Žugich, J. & Sansoni, P., Apr 2014, In : Age. 36, 2, p. 625-640 16 p.

Research output: Contribution to journalArticle

27 Scopus citations

New advances in CMV and immunosenescence

Sansoni, P., Vescovini, R., Fagnoni, F. F., Akbar, A., Arens, R., Chiu, Y. L., Čičin-Šain, L., Dechanet-Merville, J., Derhovanessian, E., Ferrando-Martinez, S., Franceschi, C., Frasca, D., Fulöp, T., Furman, D., Gkrania-Klotsas, E., Goodrum, F., Grubeck-Loebenstein, B., Hurme, M., Kern, F., Lilleri, D. & 20 others, López-Botet, M., Maier, A. B., Marandu, T., Marchant, A., Matheï, C., Moss, P., Muntasell, A., Remmerswaal, E. B. M., Riddell, N. E., Rothe, K., Sauce, D., Shin, E. C., Simanek, A. M., Smithey, M. J., Söderberg-Nauclér, C., Solana, R., Thomas, P. G., Van Lier, R., Pawelec, G. & Nikolich-Zugich, J., Jul 2014, In : Experimental Gerontology. 55, p. 54-62 9 p.

Research output: Contribution to journalArticle

83 Scopus citations
9 Scopus citations

Overcoming the limitations posed by TCRβ repertoire modeling through a GPU-based in-silico DNA recombination algorithm

Striemer, G., Krovi, H., Akoglu, A., Vincent, B., Hopson, B., Frelinger, J. & Buntzman, A., Jan 1 2014, Proceedings - IEEE 28th International Parallel and Distributed Processing Symposium, IPDPS 2014. IEEE Computer Society, p. 231-240 10 p. 6877258. (Proceedings of the International Parallel and Distributed Processing Symposium, IPDPS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness

Pickard, J. M., Maurice, C. F., Kinnebrew, M. A., Abt, M. C., Schenten, D., Golovkina, T. V., Bogatyrev, S. R., Ismagilov, R. F., Pamer, E. G., Turnbaugh, P. J. & Chervonsky, A. V., Oct 1 2014, In : Nature. 514, 7524, p. 638-641 4 p.

Research output: Contribution to journalArticle

249 Scopus citations

Sex differences in T-lymphocyte tissue infiltration and development of Angiotensin II Hypertension

Pollow, D. P., Uhrlaub, J., Romero-Aleshire, M. J., Sandberg, K., Nikolich-Zugich, J., Brooks, H. L. & Hay, M., Aug 2014, In : Hypertension. 64, 2, p. 384-390 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells

Schenten, D., Nish, S. A., Yu, S., Yan, X., Lee, H. K., Brodsky, I., Pasman, L., Yordy, B., Wunderlich, F. T., Brüning, J. C., Zhao, H. & Medzhitov, R., Jan 16 2014, In : Immunity. 40, 1, p. 78-90 13 p.

Research output: Contribution to journalArticle

61 Scopus citations

Stem cell banking for regenerative and personalized medicine

Harris, D. T., Mar 1 2014, In : Biomedicines. 2, 1, p. 50-79 30 p.

Research output: Contribution to journalReview article

20 Scopus citations
46 Scopus citations

The influence of intrinsic and extrinsic factors on immune system aging

Badowski, M., Shultz, C. L., Eason, Y., Ahmad, N. & Harris, D. T., Jun 2014, In : Immunobiology. 219, 6, p. 482-485 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

TLR2 signaling is required for the innate, but not adaptive response to LVS clpB

Roberts, L. M., Ledvina, H. E., Sempowski, G. D. & Frelinger, J. A., Jan 1 2014, In : Frontiers in immunology. 5, AUG, Article 426.

Research output: Contribution to journalArticle

4 Scopus citations

Two separate defects affecting true naive or virtual memory T cell precursors combine to reduce naive T cell responses with aging

Renkema, K. R., Li, G., Wu, A., Smithey, M. J. & Nikolich-Žugich, J., Jan 1 2014, In : Journal of Immunology. 192, 1, p. 151-159 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Using the emerging Collaborative Cross to probe the immune system

Phillippi, J., Xie, Y., Miller, D. R., Bell, T. A., Zhang, Z., Lenarcic, A. B., Aylor, D. L., Krovi, S. H., Threadgill, D. W., Pardo-Manuel De Villena, F., Wang, W., Valdar, W. & Frelinger, J. A., Jan 1 2014, In : Genes and Immunity. 15, 1, p. 38-46 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Welcome from the gems associate editors

Goodrum, F., Pfeiffer, J., Schultz-Cherry, S., Sullivan, C. & Tsai, B., 2014, In : Journal of virology. 88, 10, 1 p.

Research output: Contribution to journalEditorial

2013

Acute Neonatal Infections 'Lock-In' a Suboptimal CD8+ T Cell Repertoire with Impaired Recall Responses

Rudd, B. D., Venturi, V., Smith, N. L., Nzingha, K., Goldberg, E. L., Li, G., Nikolich-Zugich, J. & Davenport, M. P., Sep 1 2013, In : PLoS pathogens. 9, 9, e1003572.

Research output: Contribution to journalArticle

16 Scopus citations

Age-associated increase of low-avidity cytomegalovirus-specific CD8 + T cells that re-express CD45RA

Griffiths, S. J., Riddell, N. E., Masters, J., Libri, V., Henson, S. M., Wertheimer, A., Wallace, D., Sims, S., Rivino, L., Larbi, A., Kemeny, D. M., Nikolich-Zugich, J., Kern, F., Klenerman, P., Emery, V. C. & Akbar, A. N., Jun 1 2013, In : Journal of Immunology. 190, 11, p. 5363-5372 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Alterations in target cell membrane phospholipids alter T cell but not NK cell killing

Harris, D. T., Jan 1 2013, In : Immunobiology. 218, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

A transmembrane domain and GxxxG motifs within L2 are essential for papillomavirus infection

Bronnimann, M. P., Chapman, J. A., Park, C. K. & Campos, S. K., Jan 1 2013, In : Journal of virology. 87, 1, p. 464-473 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Comparison of human mesenchymal stem cells derived from adipose and cord tissue

Choudhery, M. S., Badowski, M., Muise, A. & Harris, D. T., Mar 2013, In : Cytotherapy. 15, 3, p. 330-343 14 p.

Research output: Contribution to journalArticle

67 Scopus citations

Cord blood stem cells and regenerative medicine

Harris, D. T., Jan 1 2013, Regenerative Medicine and Cell Therapy. Humana Press Inc., p. 301-312 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Human papillomavirus type 16 does not require cathepsin L or B for infection

Calton, C. M., Schlegel, A. M., Chapman, J. A. & Campos, S. K., Aug 1 2013, In : Journal of General Virology. 94, PART8, p. 1865-1869 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Identification Of Francisella novicida mutants that fail to induce prostaglandin E2 synthesis by infected macrophages

Woolard, M. D., Barrigan, L. M., Fuller, J. R., Buntzman, A. S., Bryan, J., Manoil, C., Kawula, T. H. & Frelinger, J. A., Jan 1 2013, In : Frontiers in Microbiology. 4, FEB

Research output: Contribution to journalArticle

9 Scopus citations

Infection with francisella tularensis lvs clpb leads to an altered yet protective immune response

Barrigan, L. M., Tuladhar, S., Brunton, J. C., Woolard, M. D., Chen, C. J., Saini, D., Frothingham, R., Sempowski, G. D., Kawula, T. H. & Frelinger, J. A., Jun 1 2013, In : Infection and Immunity. 81, 6, p. 2028-2042 15 p.

Research output: Contribution to journalArticle

21 Scopus citations

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

Lazear, H. M., Lancaster, A., Wilkins, C., Suthar, M. S., Huang, A., Vick, S. C., Clepper, L., Thackray, L., Brassil, M. M., Virgin, H. W., Nikolich-Zugich, J., Moses, A. V., Gale, M., Früh, K. & Diamond, M. S., Jan 1 2013, In : PLoS pathogens. 9, 1, e1003118.

Research output: Contribution to journalArticle

171 Scopus citations
7 Scopus citations

Neisseria infection of rhesus macaques as a model to study colonization, transmission, persistence, and horizontal gene transfer

Weyand, N. J., Wertheimer, A. M., Hobbs, T. R., Sisko, J. L., Taku, N. A., Gregston, L. D., Clary, S., Higashi, D. L., Biais, N., Brown, L. M., Planer, S. L., Legasse, A. W., Axthelm, M. K., Wong, S. W. & So, M., Feb 19 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 8, p. 3059-3064 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein

Zalckvar, E., Paulus, C., Tillo, D., Asbach-Nitzsche, A., Lubling, Y., Winterling, C., Strieder, N., Mücke, K., Goodrum, F., Segal, E. & Nevels, M., Aug 6 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 32, p. 13126-13131 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Polymorphisms and tissue expression of the feline leukocyte antigen class i loci FLAI-E, FLAI-H, and FLAI-K

Holmes, J. C., Holmer, S. G., Ross, P., Buntzman, A. S., Frelinger, J. A. & Hess, P. R., Sep 1 2013, In : Immunogenetics. 65, 9, p. 675-689 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
115 Scopus citations

Sigma factor RpoN (σ54) regulates pilE transcription in commensal Neisseria elongata

Rendón, M. A., Hockenberry, A. M., Mcmanus, S. A. & So, M., Oct 1 2013, In : Molecular Microbiology. 90, 1, p. 103-113 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
25 Scopus citations

Upregulation of ATF3 inhibits expression of the pro-inflammatory cytokine IL-6 during Neisseria gonorrhoeae infection

Calton, C. M., Wade, L. K. & So, M., Nov 1 2013, In : Cellular Microbiology. 15, 11, p. 1837-1850 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Utility of cryopreserved umbilical cord tissue for regenerative medicine

Choudhery, M. S., Badowski, M., Muise, A. & Harris, D. T., Jan 1 2013, In : Current Stem Cell Research and Therapy. 8, 5, p. 370-380 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Varicella zoster-specific CD4+Foxp3+ T cells accumulate after cutaneous antigen challenge in humans

Vukmanovic-Stejic, M., Sandhu, D., Sobande, T. O., Agius, E., Lacy, K. E., Riddell, N., Montez, S., Dintwe, O. B., Scriba, T. J., Breuer, J., Nikolich-Zugich, J., Ogg, G., Rustin, M. H. A. & Akbar, A. N., Feb 1 2013, In : Journal of Immunology. 190, 3, p. 977-986 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2012

Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium

Li, G., Smithey, M. J., Rudd, B. D. & Nikolich-Žugich, J., Dec 1 2012, In : Aging Cell. 11, 6, p. 968-977 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Age-related changes in CD8 T cell homeostasis and immunity to infection

Nikolich-Žugich, J., Li, G., Uhrlaub, J. L., Renkema, K. R. & Smithey, M. J., Oct 1 2012, In : Seminars in Immunology. 24, 5, p. 356-364 9 p.

Research output: Contribution to journalReview article

69 Scopus citations

Allelic diversity at the DLA-88 locus in Golden Retriever and Boxer breeds is limited

Ross, P., Buntzman, A. S., Vincent, B. G., Grover, E. N., Gojanovich, G. S., Collins, E. J., Frelinger, J. A. & Hess, P. R., Aug 1 2012, In : Tissue Antigens. 80, 2, p. 175-183 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cell-based therapy for epithelial wounds

Harris, D. T., Hilgaertner, J., Simonson, C., Ablin, R. J. & Badowski, M., Aug 2012, In : Cytotherapy. 14, 7, p. 802-810 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Changes in plasma membrane phospholipids inhibit antibody-mediated lysis

Harris, D. T., Jan 6 2012, In : Biochemical and Biophysical Research Communications. 417, 1, p. 231-236 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

CMV and Immunosenescence: From basics to clinics

Solana, R., Tarazona, R., Aiello, A. E., Akbar, A. N., Appay, V., Beswick, M., Bosch, J. A., Campos, C., Cantisán, S., Cicin-Sain, L., Derhovanessian, E., Ferrando-Martínez, S., Frasca, D., Fulöp, T., Govind, S., Grubeck-Loebenstein, B., Hill, A., Hurme, M., Kern, F., Larbi, A. & 17 others, López-Botet, M., Maier, A. B., McElhaney, J. E., Moss, P., Naumova, E., Nikolich-Zugich, J., Pera, A., Rector, J. L., Riddell, N., Sanchez-Correa, B., Sansoni, P., Sauce, D., van Lier, R., Wang, G. C., Wills, M. R., Zieliński, M. & Pawelec, G., Oct 31 2012, In : Immunity and Ageing. 9, 23.

Research output: Contribution to journalArticle

96 Scopus citations

Collection, processing, and banking of umbilical cord blood stem cells for transplantation and regenerative medicine

Badowski, M. S. & Harris, D. T., Jun 8 2012, In : Methods in Molecular Biology. 879, p. 279-290 12 p.

Research output: Contribution to journalArticle

15 Scopus citations