Research Output

2002

High-efficiency cloning system for versatile adaptation of DNA fragments

Luo, P., Tsang, T. C., Takeuchi, C., Dekker, J., Badowski, M. & Harris, D. T., Oct 1 2002, In : BioTechniques. 33, 4, p. 738-742 5 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

JP-8 jet fuel exposure results in immediate immunotoxicity, which is cumulative over time

Harris, D. T., Sakiestewa, D., Titone, D., Young, R. S. & Witten, M., Mar 2002, In : Toxicology and Industrial Health. 18, 2, p. 77-83 7 p.

Research output: Contribution to journalArticle

17 Scopus citations
2001

Biological characterization of HIV type 1 envelope V3 regions from mothers and infants associated with perinatal transmission

Matala, E., Hahn, T., Yedavalli, V. R. K. & Ahmad, N., Dec 1 2001, In : AIDS Research and Human Retroviruses. 17, 18, p. 1725-1735 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Characterization of HIV type 1 tat sequences associated with perinatal transmission

Husain, M., Hahn, T., Yedavalli, V. R. K. & Ahmad, N., Aug 9 2001, In : AIDS Research and Human Retroviruses. 17, 8, p. 765-773 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Dysregulated expression of pre-Tα reveals the opposite effects of pre-TCR at successive stages of T cell development

Lacorazza, H. D., Porritt, H. E. & Nikolich-Žugich, J., Nov 15 2001, In : Journal of Immunology. 167, 10, p. 5689-5696 8 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Functional evidence that conserved TCR CDRα3 loop docking governs the cross-recognition of closely related peptide: Class I complexes

Messaoudi, I., LeMaoult, J., Metzner, B. M., Miley, M. J., Fremont, D. H. & Nikolich-Žugich, J., Jul 15 2001, In : Journal of Immunology. 167, 2, p. 836-843 8 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
9 Scopus citations
27 Scopus citations

Mechanisms of unresponsiveness: T- and B-cell mediated mechanisms of anergy

Greenwood, R. & Frelinger, J., Jan 1 2001, In : Advances in experimental medicine and biology. 489, p. 109-117 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Molecular characterization of HIV type 1 vpu genes from mothers and infants after perinatal transmission

Yedavalli, V. R. K., Husain, M., Horodner, A. & Ahmad, N., Oct 1 2001, In : AIDS Research and Human Retroviruses. 17, 11, p. 1089-1098 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Subcellular localization of the intracellular survival-enhancing eis protein of Mycobacterium tuberculosis

Dahl, J. L., Wei, J., Moulder, J. W., Laal, S. & Friedman, R. L., Jan 1 2001, In : Infection and Immunity. 69, 7, p. 4295-4302 8 p.

Research output: Contribution to journalArticle

37 Scopus citations
2000

Construction of new amplifier expression vectors for high levels of IL-2 gene expression.

Tsang, T. C., Brailey, J. L., Vasanwala, F. H., Wu, R. S., Liu, F., Clark, P. R., Meade-Tollin, L., Luznick, L., Stopeck, A. T., Akporiaye, E. T. & Harris, D. T., Mar 2000, In : International journal of molecular medicine. 5, 3, p. 295-300 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Effects of short-term JP-8 jet fuel exposure on cell-mediated immunity

Harris, D. T., Sakiestewa, D., Robledo, R. F., Young, R. S. & Witten, M., Mar 2000, In : Toxicology and Industrial Health. 16, 2, p. 78-84 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Heat-inducible vectors for use in gene therapy

Gerner, E. W., Hersh, E. M., Pennington, M., Tsang, T. C., Harris, D., Vasanwala, F. & Brailey, J., Jan 1 2000, In : International Journal of Hyperthermia. 16, 2, p. 171-181 11 p.

Research output: Contribution to journalArticle

39 Scopus citations

Identification of a Mycobacterium tuberculosis gene that enhances mycobacterial survival in macrophages

Wei, J., Dahl, J. L., Moulder, J. W., Roberts, E. A., O'Gaora, P., Young, D. B. & Friedman, R. L., Jan 1 2000, In : Journal of bacteriology. 182, 2, p. 377-384 8 p.

Research output: Contribution to journalArticle

102 Scopus citations

Jet fuel-induced immunotoxicity

Harris, D. T., Sakiestewa, D., Titone, D., Robledo, R. F., Young, R. S. & Witten, M., Aug 2000, In : Toxicology and Industrial Health. 16, 8, p. 261-265 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Limited heterogeneity of HIV type 1 in infected mothers correlates with lack of vertical transmission

Matala, E., Crandall, K. A., Baker, R. C. & Ahmad, N., Oct 10 2000, In : AIDS Research and Human Retroviruses. 16, 15, p. 1481-1489 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Molecular mechanisms of human immunodeficiency virus type I mother-infant transmission

Ahmad, N., Dec 1 2000, Molecular Biology and Pathogenesis. p. 387-416 30 p. (Advances in Pharmacology; vol. 49).

Research output: Chapter in Book/Report/Conference proceedingChapter

14 Scopus citations

Substance P as prophylaxis for JP-8 jet fuel-induced immunotoxicity

Harris, D. T., Sakiestewa, D., Titone, D., Robledo, R. F., Young, R. S. & Witten, M., Aug 2000, In : Toxicology and Industrial Health. 16, 8, p. 253-259 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
7 Scopus citations

TNF-α is the critical mediator of the cyclic AMP-induced apoptosis of CD8+4+ double-positive thymocytes

Guevara Patiño, J. A., Ivanov, V. N., Lacy, E., Elkon, K. B., Marino, M. W. & Nikolić-Žugić, J., Feb 15 2000, In : Journal of Immunology. 164, 4, p. 1689-1694 6 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations
1999

Characterization of mother-infant HIV type 1 gag p17 sequences associated with perinatal transmission

Hahn, T., Matala, E., Chappey, C. & Ahmad, N., Jul 1 1999, In : AIDS Research and Human Retroviruses. 15, 10, p. 875-888 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo

Etemad-Moghadam, B., Sun, Y., Nicholson, E. K., Karlsson, G. B., Schenten, D. & Sodroski, J., Jan 1 1999, In : Journal of virology. 73, 10, p. 8873-8879 7 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Effects of soluble CD4 on simian immunodeficiency virus infection of CD4-positive and CD4-negative cells

Schenten, D., Marcon, L., Karlsson, G. B., Parolin, C., Kodama, T., Gerard, N. & Sodroski, J., Jan 1 1999, In : Journal of virology. 73, 7, p. 5373-5380 8 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations

Human immunodeficiency virus type 1-specific cytotoxic T lymphocyte activity is inversely correlated with HIV type 1 viral load in HIV type 1- infected long-term survivors

Betts, M. R., Krowka, J. F., Kepler, T. B., Davidian, M., Christopherson, C., Kwok, S., Louie, L., Eron, J., Sheppard, H. & Frelinger, J. A., Sep 1 1999, In : AIDS Research and Human Retroviruses. 15, 13, p. 1219-1228 10 p.

Research output: Contribution to journalArticle

105 Scopus citations

Neisseria gonorrhoeae mutants altered in toxicity to human fallopian tubes and molecular characterization of the genetic locus involved

Arvidson, C. G., Kirkpatrick, R., Witkamp, M. T., Larson, J. A., Schipper, C. A., Waldbeser, L. S., O'Gaora, P., Cooper, M. & So, M., Jan 1 1999, In : Infection and Immunity. 67, 2, p. 643-652 10 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Prevention of graft-versus-host disease (GVHD) by elimination of recipient-reactive donor T cells with recombinant toxins that target the interleukin 2 (IL-2) receptor

Harris, D. T., Sakiestewa, D., Lyons, C., Kreitman, R. J. & Pastan, I., Jan 1 1999, In : Bone Marrow Transplantation. 23, 2, p. 137-144 8 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations
1998

Conservation of an intact vif gene of human immunodeficiency virus type 1 during maternal-fetal transmission

Yedavalli, V. R. K., Chappey, C., Matala, E. & Ahmad, N., Feb 1 1998, In : Journal of virology. 72, 2, p. 1092-1102 11 p.

Research output: Contribution to journalArticle

28 Scopus citations
5 Scopus citations

Host priming, not target antigen type, decides rejection rate in mice primed with MHC II 'knockout' cultured keratinocytes

Hunt, J. P., Hunter, C. T., Brownstein, M., Hultman, C. S., DeSerres, S., Bracey, L., Frelinger, J. & Meyer, A. A., Apr 1998, In : Journal of Surgical Research. 76, 1, p. 32-36 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Identification of Btr-regulated genes using a titration assay. Search for a role for this transcriptional regulator in the growth and virulence of Bordetella pertussis

Wood, G. E., Khele, N., Guiso, N. & Friedman, R. L., Mar 16 1998, In : Gene. 209, 1-2, p. 51-58 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Maintenance of an intact human immunodeficiency virus type 1 vpr gene following mother-to-infant transmission

Yedavalli, V. R. K., Chappey, C. & Ahmad, N., Aug 1 1998, In : Journal of virology. 72, 8, p. 6937-6943 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

The effector component of the cytotoxic T-lymphocyte response has a biphasic pattern after burn injury

Hunt, J. P., Hunter, C. T., Brownstein, M. R., Giannopoulos, A., Hultman, C. S., Deserres, S., Bracey, L., Frelinger, J. & Meyer, A. A., Dec 1998, In : Journal of Surgical Research. 80, 2, p. 243-251 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
1997

Cloning and characterization of the Neisseria meningitidis rfaC gene encoding α-1,5 heptosyltransferase I

Stojiljkovic, I., Hwa, V., Larson, J., Lin, L., So, M. & Nassif, X., Jun 1 1997, In : FEMS Microbiology Letters. 151, 1, p. 41-49 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Human gene therapy for melanoma: CT-guided interstitial injection

Waddill, W., Wright, W., Unger, E., Stopeck, A., Akporiaye, E., Harris, D., Grogan, T., Schluter, S., Hersh, E. & Stahl, S., Jul 1997, In : American Journal of Roentgenology. 169, 1, p. 63-67 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Immunotoxicological effects of JP-8 jet fuel exposure

Harris, D. T., Sakiestewa, D., Robledo, R. F. & Witten, M., Jan 1 1997, In : Toxicology and Industrial Health. 13, 1, p. 43-55 13 p.

Research output: Contribution to journalArticle

81 Scopus citations

Mammalian expression vector with two multiple cloning sites for expression of two foreign genes

Tsang, T. C., Harris, D. T., Akporiaye, E. T., Chu, R. S., Brailey, J., Liu, F., Vasanwala, F. H., Schluter, S. F. & Hersh, E. M., Jan 1 1997, In : BioTechniques. 22, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Phase I study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in patients with metastatic melanoma

Stopeck, A. T., Hersh, E. M., Akporiaye, E. T., Harris, D. T., Grogan, T., Unger, E., Warneke, J., Schluter, S. F. & Stahl, S., Jan 1997, In : Journal of Clinical Oncology. 15, 1, p. 341-349 9 p.

Research output: Contribution to journalArticle

134 Scopus citations

Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7

Rubin, J., Galanis, E., Pitot, H. C., Richardson, R. L., Burch, P. A., Charboneau, J. W., Reading, C. C., Lewis, B. D., Stahl, S., Akporiaye, E. T. & Harris, D. T., Jan 1 1997, In : Gene Therapy. 4, 5, p. 419-425 7 p.

Research output: Contribution to journalArticle

Open Access
103 Scopus citations

Protection from JP-8 jet fuel induced immunotoxicity by administration of aerosolized substance P

Harris, D. T., Sakiestewa, D., Robledo, R. F. & Witter, M., Sep 1997, In : Toxicology and Industrial Health. 13, 5, p. 571-588 18 p.

Research output: Contribution to journalArticle

36 Scopus citations

Short-term exposure to JP-8 jet fuel results in longterm immunotoxicity

Harris, D. T., Sakiestewa, D., Robledo, R. F. & Wittent, M., Sep 1997, In : Toxicology and Industrial Health. 13, 5, p. 559-570 12 p.

Research output: Contribution to journalArticle

62 Scopus citations
1996

Effects of HIV-1 Tat on expression of HLA class I molecules

Matsui, M., Warburton, R. J., Cogswell, P. C., Baldwin, A. S. & Frelinger, J. A., Jan 1 1996, In : Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 11, 3, p. 233-240 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Experience in autologous and allogeneic cord blood banking

Harris, D. T., Apr 1 1996, In : Journal of Hematotherapy and Stem Cell Research. 5, 2, p. 123-128 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

In vivo and in vitro analysis of Bordetella pertussis catalase and Fe-superoxide dismutase mutants

Khelef, N., DeShazer, D., Friedman, R. L. & Guiso, N., Sep 1 1996, In : FEMS Microbiology Letters. 142, 2-3, p. 231-235 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Maternal-fetal transmission of human immunodeficiency virus

Ahmad, N., Jan 1 1996, In : Journal of Biomedical Science. 3, 4, p. 238-250 13 p.

Research output: Contribution to journalReview article

21 Scopus citations

Simple method for adapting DNA fragments and PCR products to all of the commonly used restriction sites

Tsang, T. C., Harris, D. T., Akporiaye, E. T., Schluter, S. F., Bowden, G. T. & Hersh, E. M., Jan 1 1996, In : BioTechniques. 20, 1, p. 51-52 2 p.

Research output: Contribution to journalArticle

8 Scopus citations
1995

Burn injury impairs second-set rejection and CTL reactivity in mice primed by cultured keratinocyte allografts

Hultman, C. S., Cairns, B. A., DeSerres, S., Frelinger, J. A. & Meyer, A. A., Sep 1995, In : Transplantation. 60, 6, p. 584-589 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Different MHC class I alleles compete for presentation of overlapping viral epitopes

Tussey, L. G., Rowland-Jones, S., Zheng, T. S., Androlewicz, M. J., Cresswell, P., Frelinger, J. A. & McMichael, A. J., Jul 1995, In : Immunity. 3, 1, p. 65-77 13 p.

Research output: Contribution to journalArticle

68 Scopus citations