Research Output

2019

Validating Enterovirus D68-2A pro as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2A pro Inhibitor

Musharrafieh, R., Ma, C., Zhang, J., Hu, Y., Diesing, J. M., Marty, M. T. & Wang, J., Apr 1 2019, In : Journal of virology. 93, 7

Research output: Contribution to journalArticle

8 Scopus citations

Variability in total serum IgE over 1 year in severe asthmatics

Louis, R., Pilette, C., Michel, O., Michils, A., Brusselle, G., Poskin, A., Van Schoor, J., Denhaerynck, K., Vancayzeele, S., Abraham, I. & Gurdain, S., Mar 29 2019, In : Allergy, Asthma and Clinical Immunology. 15, 1, 20.

Research output: Contribution to journalArticle

3 Scopus citations

When less is more: Opioid use in the emergency department

Patanwala, A. E., Oct 17 2019, In : American Journal of Health-System Pharmacy. 76, 22, p. 1812-1813 2 p.

Research output: Contribution to journalEditorial

Why health policies should be transnational: A case for East Asia Pacific countries

Ambade, P. N., Katragadda, C., Sun, D., Bootman, J. L. & Abraham, I., Jan 1 2019, In : International Journal of Risk and Safety in Medicine. 30, 2, p. 101-125 25 p.

Research output: Contribution to journalArticle

X-ray Crystal Structure of the Influenza A M2 Proton Channel S31N Mutant in Two Conformational States: An Open and Shut Case

Thomaston, J. L., Wu, Y., Polizzi, N., Liu, L., Wang, J. & Degrado, W. F., Jul 24 2019, In : Journal of the American Chemical Society. 141, 29, p. 11481-11488 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

A catalogue of somatic NRF2 gain-of-function mutations in cancer

Kerins, M. J. & Ooi, A., Dec 1 2018, In : Scientific reports. 8, 1, 12846.

Research output: Contribution to journalArticle

20 Scopus citations

A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B)

François-Moutal, L., Jahanbakhsh, S., Nelson, A. D. L., Ray, D., Scott, D. D., Hennefarth, M. R., Moutal, A., Perez-Miller, S., Ambrose, A. J., Al-Shamari, A., Coursodon, P., Meechoovet, B., Reiman, R., Lyons, E., Beilstein, M., Chapman, E., Morris, Q. D., Van Keuren-Jensen, K., Hughes, T. R., Khanna, R. & 4 others, Koehler, C., Jen, J., Gokhale, V. & Khanna, M., Oct 19 2018, In : ACS Chemical Biology. 13, 10, p. 3000-3010 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2 Scopus citations

A CYP2B6-humanized mouse model and its potential applications

Li, L., Zhang, Q. Y. & Ding, X., Feb 2018, In : Drug Metabolism and Pharmacokinetics. 33, 1, p. 2-8 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single cells

Wang, S., Xiao, Y., Zhang, D. D. & Wong, P. K., Feb 2018, In : Biomaterials. 156, p. 56-64 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Albumin disposition in critically Ill patients

Erstad, B. L., Jan 1 2018, (Accepted/In press) In : Journal of Clinical Pharmacy and Therapeutics.

Research output: Contribution to journalArticle

Alcohol metabolism in the progression of human nonalcoholic steatohepatitis

Li, H., Toth, E. & Cherrington, N. J., 2018, In : Toxicological Sciences. 164, 2, p. 428-438 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

An assisted living interprofessional education and practice geriatric screening clinic (IPEP-GSC): a description and evaluation

Lee, J. K., Cioltan, H., Goldsmith, P., Heasley, B., Dermody, M., Fain, M. J. & Mohler, M. J., Apr 14 2018, (Accepted/In press) In : Gerontology and Geriatrics Education. p. 1-12 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

An observational study of pain self-management strategies and outcomes: Does type of pain, age, or gender, matter?

Slack, M. K., Chavez, R., Trinh, D., De Dios, D. V. & Lee, J. K., Jul 11 2018, (Accepted/In press) In : Scandinavian Journal of Pain.

Research output: Contribution to journalArticle

3 Scopus citations

An update on the prevalence and incidence of epilepsy among older adults

Ip, Q., Malone, D. C., Chong, J. W., Harris, R. B. & Labiner, D. M., Jan 1 2018, In : Epilepsy Research. 139, p. 107-112 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Are teaching hospitals treated fairly in the hospital-acquired condition reduction program?

Al Mohajer, M., Joiner, K. A. & Nix, D. E., Jan 1 2018, In : Academic Medicine. 93, 12, p. 1827-1832 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Are US Health Insurers Efficient or Not?

Malone, D. C., Apr 1 2018, In : Value in Health. 21, 4, p. 398-399 2 p.

Research output: Contribution to journalEditorial

A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells

Ray, S., Corenblum, M. J., Anandhan, A., Reed, A., Ortiz, F. O., Zhang, D. D., Barnes, C. A. & Madhavan, L., Apr 1 2018, In : Cell transplantation. 27, 4, p. 589-606 18 p.

Research output: Contribution to journalArticle

11 Scopus citations

Arsenic methylation capacity in relation to nutrient intake and genetic polymorphisms in one-carbon metabolism

Gamboa-Loira, B., Hernández-Alcaraz, C., Gandolfi, A. J., Cebrián, M. E., Burguete-García, A., García-Martínez, A. & López-Carrillo, L., Jul 1 2018, In : Environmental Research. 164, p. 18-23 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

A rule of unity for human intestinal absorption 3: Application to pharmaceuticals

Patel, R. B. & Yalkowsky, S. H., Feb 1 2018, In : Biopharmaceutics and Drug Disposition. 39, 2, p. 67-74 8 p.

Research output: Contribution to journalArticle

A scoping review of the quality and the design of evaluations of mobile health, telehealth, smart pump and monitoring technologies performed in a pharmacy-related setting

Baines, D., Gahir, I. K., Hussain, A., Khan, A. J., Schneider, P., Hasan, S. S. & Babar, Z. U. D., Jul 26 2018, In : Frontiers in Pharmacology. 9, JUL, 678.

Research output: Contribution to journalReview article

Open Access
7 Scopus citations

A single-arm, retrospective analysis of the incidence of febrile neutropenia using same-day versus next-day pegfilgrastim in patients with gastrointestinal cancers treated with FOLFOX or FOLFIRI

Eckstrom, J., Bartels, T., Abraham, I., Patel, H., Elquza, E., Scott, A. J., Malangone, S., Hollings, J. & McBride, A., Jan 1 2018, (Accepted/In press) In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

2 Scopus citations
9 Scopus citations

Assessing the incidence of acidosis in patients receiving metformin with and without risk factors for lactic acidosis

Trinkley, K. E., Anderson, H. D., Nair, K. V., Malone, D. C. & Saseen, J. J., Sep 1 2018, In : Therapeutic Advances in Chronic Disease. 9, 9, p. 179-190 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

Mosley, J. D., Feng, Q. P., Wells, Q. S., Van Driest, S. L., Shaffer, C. M., Edwards, T. L., Bastarache, L., Wei, W. Q., Davis, L. K., McCarty, C. A., Thompson, W., Chute, C. G., Jarvik, G. P., Gordon, A. S., Palmer, M. R., Crosslin, D. R., Larson, E. B., Carrell, D. S., Kullo, I. J., Pacheco, J. A. & 14 others, Peissig, P. L., Brilliant, M. H., Linneman, J. G., Namjou, B., Williams, M. S., Ritchie, M. D., Borthwick, K. M., Verma, S. S., Karnes, J. H., Weiss, S. T., Wang, T. J., Stein, C. M., Denny, J. C. & Roden, D. M., Dec 1 2018, In : Nature communications. 9, 1, 3522.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

A suite of DNA methylation markers that can detect most common human cancers

Vrba, L. & Futscher, B. W., Jan 2 2018, In : Epigenetics. 13, 1, p. 61-72 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
37 Scopus citations
7 Scopus citations

BRCA1 and BRCA2 Gene Mutations and Colorectal Cancer Risk: Systematic Review and Meta-analysis

Oh, M., McBride, A., Yun, S., Bhattacharjee, S., Slack, M. K., Martin, J. R., Jeter, J. M. & Abraham, I. L., Nov 1 2018, In : Journal of the National Cancer Institute. 110, 11, p. 1178-1189 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-3

Mangoni, A. A., Tuccinardi, T., Collina, S., Vanden Eynde, J. J., Mu oz-Torrero, D., Karaman, R., Siciliano, C., Emília de Sousa, M., Prokai-Tatrai, K., Rautio, J., Guillou, C., G tschow, M., Galdiero, S., Liu, H., Agrofoglio, L. A., Sabatier, J. M., Hulme, C., Kokotos, G., You, Q. & Gomes, P. A. C., 2018, In : Molecules. 23, 7, 1596.

Research output: Contribution to journalReview article

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes–2

Muñoz-Torrero, D., Mangoni, A. A., Liu, H., Hulme, C., Rautio, J., Karaman, R., De Sousa, M. E., Prokai-Tatrai, K., Sabatier, J. M., Siciliano, C., Luque, F. J., Kokotos, G., Ragno, R., Collina, S., Guillou, C., Tschow, M. G. & Agrofoglio, L. A., 2018, In : Molecules. 23, 1, 65.

Research output: Contribution to journalReview article

1 Scopus citations

Cardiotoxic effects of chemotherapy: A review of both cytotoxic and molecular targeted oncology therapies and their effect on the cardiovascular system

Babiker, H. M., McBride, A., Newton, M., Boehmer, L. M., Drucker, A. G., Gowan, M., Cassagnol, M., Camenisch, T. D., Anwer, F. . & Hollands, J. M., Jun 1 2018, In : Critical Reviews in Oncology/Hematology. 126, p. 186-200 15 p.

Research output: Contribution to journalReview article

27 Scopus citations

Catalyst free, C-3 functionalization of imidazo[1,2-a]pyridines to rapidly access new chemical space for drug discovery efforts

Gunaganti, N., Kharbanda, A., Lakkaniga, N. R., Zhang, L., Cooper, R., Li, H. Y. & Frett, B., Jan 1 2018, In : Chemical Communications. 54, 92, p. 12954-12957 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region

Seira, N., Yamagata, K., Fukushima, K., Araki, Y., Kurata, N., Yanagisawa, N., Mashimo, M., Nakamura, H., Regan, J. W., Murayama, T. & Fujino, H., Dec 2018, In : Pharmacology Research and Perspectives. 6, 6, e00441.

Research output: Contribution to journalArticle

1 Scopus citations

Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels

François-Moutal, L., Scott, D. D., Perez-Miller, S., Gokhale, V., Khanna, M. & Khanna, R., Jan 1 2018, In : Channels. 12, 1, p. 219-227 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Clinical research that matters: Designing outcome-based research for older adults to qualify for systematic reviews and meta-analyses

Lee, J. K., Fosnight, S. M., Estus, E. L., Evans, P. J., Pho, V. B., Reidt, S., Reist, J. C., Ruby, C. M., Sibicky, S. L. & Wheeler, J. B., Jan 1 2018, In : Consultant Pharmacist. 33, 1, p. 24-32 9 p.

Research output: Contribution to journalArticle

Comparison of 3-Factor Versus 4-Factor Prothrombin Complex Concentrate With Regard to Warfarin Reversal, Blood Product Use, and Costs

DeAngelo, J., Jarrell, D., Cosgrove, R., Camamo, J., Edwards, C. & Patanwala, A. E., May 1 2018, In : American Journal of Therapeutics. 25, 3, p. e326-e332

Research output: Contribution to journalArticle

9 Scopus citations

Comparison of blood product use and costs with use of 3-factor versus 4-factor prothrombin complex concentrate for off-label indications

DeAngelo, J., Jarrell, D. H., Cosgrove, R., Camamo, J., Edwards, C. J. & Patanwala, A. E., Aug 1 2018, In : American Journal of Health-System Pharmacy. 75, 15, p. 1103-1109 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Comparison of drug administration logistics between prothrombin complex concentrates and plasma in the emergency department

Alarfaj, S. J., Jarrell, D. H. & Patanwala, A. E., Jan 1 2018, (Accepted/In press) In : American Journal of Emergency Medicine.

Research output: Contribution to journalArticle

2 Scopus citations

Comparison of lower-dose versus higher-dose intravenous naloxone on time to recurrence of opioid toxicity in the emergency department

Wong, F., Edwards, C. J., Jarrell, D. H. & Patanwala, A. E., Jan 1 2018, (Accepted/In press) In : Clinical Toxicology.

Research output: Contribution to journalArticle

3 Scopus citations

Conceptualising production, productivity and technology in pharmacy practice: A novel framework for policy, education and research

Baines, D., Bates, I., Bader, L., Hale, C. & Schneider, P., Oct 3 2018, In : Human Resources for Health. 16, 1, 51.

Research output: Contribution to journalArticle

7 Scopus citations
2 Scopus citations
6 Scopus citations

Dietary flavonoids improve urinary arsenic elimination among Mexican women

Quiller, G., Mérida-Ortega, Á., Rothenberg, S. J., Cebrián, M. E., Gandolfi, A. J., Franco-Marina, F. & López-Carrillo, L., Jul 2018, In : Nutrition Research. 55, p. 65-71 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Direct oral anticoagulants for extended thromboprophylaxis in medically ill patients: Meta-analysis and risk/benefit assessment

Al Yami, M. S., Kurdi, S. & Abraham, I., Feb 21 2018, In : Journal of Blood Medicine. 9, p. 25-34 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Discovery of Highly Potent Pinanamine-Based Inhibitors against Amantadine- and Oseltamivir-Resistant Influenza A Viruses

Zhao, X., Li, R., Zhou, Y., Xiao, M., Ma, C., Yang, Z., Zeng, S., Du, Q., Yang, C., Jiang, H., Hu, Y., Wang, K., Mok, C. K. P., Sun, P., Dong, J., Cui, W., Wang, J., Tu, Y., Yang, Z. & Hu, W., Jun 28 2018, In : Journal of Medicinal Chemistry. 61, 12, p. 5187-5198 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Economic Evaluation for the UK of Systemic Chemotherapies as First-Line Treatment of Metastatic Pancreatic Cancer

Gharaibeh, M., McBride, A., Alberts, D. S., Erstad, B. L., Slack, M. K., Alsaid, N., Bootman, J. L. & Abraham, I. L., Jul 6 2018, (Accepted/In press) In : PharmacoEconomics. p. 1-11 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Economic Evaluation for USA of Systemic Chemotherapies as First-Line Treatment of Metastatic Pancreatic Cancer

Gharaibeh, M., McBride, A., Alberts, D. S., Slack, M. K., Erstad, B. L., Alsaid, N., Bootman, J. L. & Abraham, I. L., Jun 9 2018, (Accepted/In press) In : PharmacoEconomics. p. 1-12 12 p.

Research output: Contribution to journalArticle