Research Output 1965 2020

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Article
2020
Amantadine
Influenza A virus
Drug Delivery Systems
Rimantadine
Antiviral Agents

Hepatic and intestinal biotransformation gene expression and drug disposition in a dextran sulfate sodium-induced colitis mouse model

Fan, X., Ding, X. & Zhang, Q. Y., Jan 2020, In : Acta Pharmaceutica Sinica B. 10, 1, p. 123-135 13 p.

Research output: Contribution to journalArticle

Open Access
Dextran Sulfate
Colitis
Biotransformation
Gene Expression
Liver

Salinomycin and its derivatives as potent RET transcriptional inhibitors for the treatment of medullary thyroid carcinoma

Alqahtani, T., Kumarasamy, V. M., Huczyński, A. & Sun, D., Jan 1 2020, In : International journal of oncology. 56, 1, p. 348-358 11 p.

Research output: Contribution to journalArticle

Flow Cytometry
Cyclin D
Retinoblastoma Protein
Mutation
Wnt Signaling Pathway
2019
Chronic Pain
Opioid Analgesics
Pain Management
Odds Ratio
Pain

A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78

Ambrose, A. J., Zerio, C. J., Sivinski, J., Schmidlin, C. J., Shi, T., Ross, A. B., Widrick, K. J., Johnson, S. M., Zhang, D. & Chapman, E., Jul 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 14, p. 1689-1693 5 p.

Research output: Contribution to journalArticle

Hexachlorophene
HSP70 Heat-Shock Proteins
Assays
Throughput
Substrates
2 Citations (Scopus)

Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control

Lytvynenko, I., Paternoga, H., Thrun, A., Balke, A., Müller, T. A., Chiang, C. H., Nagler, K., Tsaprailis, G., Anders, S., Bischofs, I., Maupin-Furlow, J. A., Spahn, C. M. T. & Joazeiro, C. A. P., Jun 27 2019, In : Cell. 178, 1, p. 76-90.e22

Research output: Contribution to journalArticle

Proteolysis
Ribosomes
Quality Control
Alanine
Quality control

Alternaria induces airway epithelial cytokine expression independent of protease-activated receptor

Daines, M., Zhu, L., Pereira, R., Zhou, X., Bondy, C., Pryor, B. M., Zhou, J. & Chen, Y., Jan 1 2019, (Accepted/In press) In : Respirology.

Research output: Contribution to journalArticle

Proteinase-Activated Receptors
Alternaria
PAR-2 Receptor
Cytokines
Asthma
Open Access
Rivastigmine
Alzheimer Disease
Hospitalization
Cohort Studies
Retrospective Studies
2 Citations (Scopus)

Analysis of networks of host proteins in the early time points following HIV transduction

Csosz, É., Tóth, F., Mahdi, M., Tsaprailis, G., Emri, M. & Tozsér, J., Jul 17 2019, In : BMC bioinformatics. 20, 1, 398.

Research output: Contribution to journalArticle

Open Access
Proteomics
HIV
Proteins
Protein
Weighted Networks
1 Citation (Scopus)

An Isoform-Selective PTP1B Inhibitor Derived from Nitrogen-Atom Augmentation of Radicicol

Shi, T., Kithsiri Wijeratne, E. M., Solano, C., Ambrose, A. J., Ross, A. B., Norwood, C., Orido, C. K., Grigoryan, T., Tillotson, J., Kang, M., Luo, G., Keegan, B. M., Hu, W., Blagg, B. S. J., Zhang, D., Gunatilaka, L. & Chapman, E., Jul 30 2019, In : Biochemistry. 58, 30, p. 3225-3231 7 p.

Research output: Contribution to journalArticle

hydrazine
Protein Isoforms
Nitrogen
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Derivatives

A Novel Capsid Binding Inhibitor Displays Potent Antiviral Activity against Enterovirus D68

Ma, C., Hu, Y., Zhang, J., Musharrafieh, R. & Wang, J., Jan 1 2019, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Enterovirus
Capsid
Antiviral Agents
Virus Uncoating
Enterovirus Infections
1 Citation (Scopus)

A One-Step, Atom Economical Synthesis of Thieno[2,3-d]pyrimidin-4-amine Derivatives by a Four-Component Reaction

Shi, T., Zerio, C. J., Sivinski, J., Ambrose, A. J., Moore, K. T., Buckley, T., Kaneko, L., Zhang, M., Zhang, D. & Chapman, E., Jun 2 2019, In : European Journal of Organic Chemistry. 2019, 20, p. 3269-3272 4 p.

Research output: Contribution to journalArticle

Ketones
Amines
amines
Phosphotransferases
Derivatives

A Quantitative and Qualitative Analysis of Electronic Prescribing Incidents Reported by Community Pharmacists

Hincapie, A. L., Alamer, A., Sears, J., Warholak, T. L., Goins, S. & Weinstein, S. D., May 5 2019, In : Applied Clinical Informatics. 10, 3, p. 387-394 8 p.

Research output: Contribution to journalArticle

Electronic Prescribing
Pharmacists
Drug therapy
Prescriptions
Databases

ASHP national survey of pharmacy practice in hospital settings: Workforce-2018

Schneider, P. J., Pedersen, C. A., Ganio, M. C. & Scheckelhoff, D. J., Jul 18 2019, In : American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 76, 15, p. 1127-1141 15 p.

Research output: Contribution to journalArticle

Pharmacists
Health
Credentialing
Foster Home Care
Postal Service
1 Citation (Scopus)

ASHP national survey of pharmacy practice in hospital settings: Monitoring and patient education-2018

Pedersen, C. A., Schneider, P. J., Ganio, M. C. & Scheckelhoff, D. J., Jul 2 2019, In : American Journal of Health-System Pharmacy. 76, 14, p. 1038-1058 21 p., zxz099.

Research output: Contribution to journalArticle

Patient Education
Pharmacists
Opioid Analgesics
Medication Therapy Management
Surveys and Questionnaires

Assessing the effect of a telepharmacist's recommendations during an integrated, interprofessional telehealth appointment and their alignment with quality measures

Tetuan, C., Axon, D. R., Bingham, J., Boesen, K., Lipsy, R., Scovis, N., Taylor, A. M., Warholak, T., Lott, B. E. & Leal, S., Jan 1 2019, In : Journal of Managed Care and Specialty Pharmacy. 25, 12, p. 1334-1339A

Research output: Contribution to journalArticle

Telemedicine
Pharmacists
Appointments and Schedules
Health
Electronic Health Records

Assessment of YAP gene polymorphisms and arsenic interaction in Mexican women with breast cancer

Michel-Ramirez, G., Recio-Vega, R., Lantz, R. C., Gandolfi, A. J., Olivas-Calderon, E., Chau, B. T. & Amistadi, M. K., Jan 1 2019, (Accepted/In press) In : Journal of Applied Toxicology.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Biodegradability and toxicity of monorhamnolipid biosurfactant diastereomers

Hogan, D. E., Tian, F., Malm, S. W., Olivares, C., Palos Pacheco, R., Simonich, M. T., Hunjan, A. S., Tanguay, R. L., Klimecki, W., Polt, R. L., Pemberton, J. E., Curry, J. E. & Maier, R. M., Feb 15 2019, In : Journal of Hazardous Materials. 364, p. 600-607 8 p.

Research output: Contribution to journalArticle

Biodegradability
Zebrafish
Toxicity
Assays
assay
5 Citations (Scopus)

Biosimilars: Considerations for payers

Smeeding, J., Malone, D. C., Ramchandani, M., Stolshek, B., Green, L. & Schneider, P. J., Jan 1 2019, In : P and T. 44, 2, p. 54-63 10 p.

Research output: Contribution to journalArticle

Biosimilar Pharmaceuticals
Pharmaceutical Economics
Managed Care Programs

Blood glucose reduction in patients treated with insulin and dextrose for hyperkalaemia

Aljabri, A., Perona, S., Alshibani, M., Khobrani, M., Jarrell, D. & Patanwala, A. E., Jan 1 2019, (Accepted/In press) In : Emergency Medicine Journal.

Research output: Contribution to journalArticle

Hyperkalemia
Blood Glucose
Hypoglycemia
Insulin
Glucose
2 Citations (Scopus)

Cardiac Dysrhythmias Associated With Substitutive Use of Loperamide: A Systematic Review

Riaz, I. B., Khan, M. S., Kamal, M. U., Sipra, Q. U. A. R., Riaz, A., Zahid, U. & Bhattacharjee, S., Jan 1 2019, In : American Journal of Therapeutics. 26, 1, p. e170-e182

Research output: Contribution to journalArticle

Loperamide
Cardiac Arrhythmias
Cytochrome P-450 CYP3A
Cimetidine
Spasm

Catalytic asymmetric synthesis of 2,5-dihydrofurans using synergistic bifunctional Ag catalysis

Shi, T., Teng, S., Gopi Krishna Reddy, A., Guo, X., Zhang, Y., Moore, K. T., Buckley, T., Mason, D. J., Wang, W., Chapman, E. & Hu, W., Jan 1 2019, In : Organic and Biomolecular Chemistry. 17, 38, p. 8737-8744 8 p.

Research output: Contribution to journalArticle

Alkynes
alkynes
Catalysis
catalysis
catalysts

Characterization of Tetracycline Hydrochloride Compounded in a Miracle Mouthwash Formulation

Younis, U. S., Fazel, M. & Myrdal, P. B., Jul 1 2019, In : AAPS PharmSciTech. 20, 5, 178.

Research output: Contribution to journalArticle

Mouthwashes
Tetracycline
tetracycline
active ingredients
thermogravimetry
3 Citations (Scopus)

Chemotherapy-induced neutropenia/febrile neutropenia prophylaxis with biosimilar filgrastim in solid tumors versus hematological malignancies: MONITOR-GCSF study

Ludwig, H., Bokemeyer, C., Aapro, M., Boccadoro, M., Gascón, P., Denhaerynck, K., Krendyukov, A., Abraham, I. L. & Macdonald, K., Mar 1 2019, In : Future Oncology. 15, 8, p. 897-907 11 p.

Research output: Contribution to journalArticle

Open Access
Biosimilar Pharmaceuticals
Febrile Neutropenia
Hematologic Neoplasms
Neutropenia
Drug Therapy
2 Citations (Scopus)

Chronic Dyrk1 Inhibition Delays the Onset of AD-Like Pathology in 3xTg-AD Mice

Velazquez, R., Meechoovet, B., Ow, A., Foley, C., Shaw, A., Smith, B., Oddo, S. ., Hulme, C. & Dunckley, T., Jan 1 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Alzheimer Disease
Neurofibrillary Tangles
Pathology
Amyloid Plaques
Amyloid beta-Protein Precursor

Clinical and cost outcomes of pre-emptive plerixafor administration in patients with multiple myeloma undergoing stem cell mobilization

Andritsos, L. A., Huang, Y., Abraham, I. L., Huff, K., Scrape, S. R., Fan, T., Alkhatib, N., Hofmeister, C. C., Drea, E. & McBride, A., Oct 1 2019, In : Leukemia Research. 85, 106215.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Mobilization
Multiple Myeloma
Costs and Cost Analysis
Stem Cells
Logistic Models

Clinical medication review type III of polypharmacy reduced unplanned hospitalizations in older adults: A meta-analysis of randomized clinical trials

Mizokami, F., Mizuno, T., Kanamori, K., Oyama, S., Nagamatsu, T., Lee, J. K. & Kobayashi, T., Dec 1 2019, In : Geriatrics and Gerontology International. 19, 12, p. 1275-1281 7 p.

Research output: Contribution to journalArticle

Polypharmacy
hospitalization
Meta-Analysis
Hospitalization
medication

Clinical Pharmacist–Led Impact on Inappropriate Albumin Use and Costs in the Critically Ill

Buckley, M. S., Knutson, K. D., Agarwal, S. K., Lansburg, J. M., Wicks, L. M., Saggar, R. C., Richards, E. C., Kopp, B. J. & Erstad, B. L., Jan 1 2019, (Accepted/In press) In : Annals of Pharmacotherapy.

Research output: Contribution to journalArticle

Critical Illness
Albumins
Costs and Cost Analysis
Intensive Care Units
Pharmacists
1 Citation (Scopus)

Clinician preferences for computerised clinical decision support for medications in primary care: A focus group study

Trinkley, K. E., Blakeslee, W. W., Matlock, D. D., Kao, D. P., Van Matre, A. G., Harrison, R., Larson, C. L., Kostman, N., Nelson, J. A., Lin, C. T. & Malone, D. C., Apr 1 2019, In : BMJ Health and Care Informatics. 26, 1, 000015.

Research output: Contribution to journalArticle

Clinical Decision Support Systems
Focus Groups
Primary Health Care
Workflow
Practice Guidelines

Collective Cell Migration in 3D Epithelial Wound Healing

Xiao, Y., Riahi, R., Torab, P., Zhang, D. & Wong, P. K., Jan 1 2019, In : ACS Nano.

Research output: Contribution to journalArticle

wound healing
Actins
Ablation
Gene expression
cells

Comparing the efficacy and safety of faecal microbiota transplantation with bezlotoxumab in reducing the risk of recurrent Clostridium difficile infections: A systematic review and Bayesian network meta-analysis of randomised controlled trials

Alhifany, A. A., Almutairi, A. R., Almangour, T. A., Shahbar, A. N., Abraham, I., Alessa, M., Alnezary, F. S. & Cheema, E., Nov 1 2019, In : BMJ open. 9, 11, e031145.

Research output: Contribution to journalArticle

Open Access
Clostridium Infections
Clostridium difficile
Randomized Controlled Trials
Safety
Anti-Bacterial Agents

Comprehensive lifestyle improvement program for prostate cancer (CLIPP): Protocol for a feasibility and exploratory efficacy study in men on androgen deprivation therapy

Algotar, A., Hsu, C-H., Chow, H-H., Dougherty, S., Babiker, H. M., Marrero, D., Abraham, I. L., Kumar, R., Ligibel, J., Courneya, K. S. & Thomson, C., Feb 1 2019, In : Journal of medical Internet research. 21, 2, e12579.

Research output: Contribution to journalArticle

Open Access
Androgens
Life Style
Prostatic Neoplasms
Quality of Life
Clinical Trials

Concurrent Inhibition of Vesicular Monoamine Transporter 2 Does Not Protect Against 3,4-Methylenedioxymethamphetamine (Ecstasy) Induced Neurotoxicity

Cholanians, A. B., Phan, A. V., Lau, S. S. & Monks, T., Jul 1 2019, In : Toxicological Sciences. 170, 1, p. 157-166 10 p.

Research output: Contribution to journalArticle

Vesicular Monoamine Transport Proteins
N-Methyl-3,4-methylenedioxyamphetamine
2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-ol
Rats
Body Temperature
Niclosamide
Drug Repositioning
Biological Availability
Liver
Intestines

Co-sensitization and cross-reactivity of Blomia tropicalis with two Dermatophagoides species in Guangzhou, China

Liu, X., Zheng, P., Zheng, S. G., Zhai, Y., Zhao, X., Chen, Y., Cai, C., Wu, Z., Huang, Z., Zou, X., Liao, C. & Sun, B., Nov 1 2019, In : Journal of Clinical Laboratory Analysis. 33, 9, e22981.

Research output: Contribution to journalArticle

Open Access
Dermatophagoides farinae
Pyroglyphidae
Dermatophagoides pteronyssinus
Immunoglobulin E
China
docetaxel
Castration
Prednisone
Cost-Benefit Analysis
Prostatic Neoplasms
5 Citations (Scopus)

Current Concepts and Future Directions in the Pharmacology and Treatment of Coccidioidomycosis

Thompson, G. R., Lewis, J. S., Nix, D. E. & Patterson, T. F., Feb 1 2019, In : Medical Mycology. 57, 1, p. S76-S84

Research output: Contribution to journalArticle

Coccidioidomycosis
Fluconazole
Pharmacology
Coccidioides
Asymptomatic Infections

Development of a biomarker mortality risk model in acute respiratory distress syndrome

Bime, C., Casanova, N., Oita, R. C., Ndukum, J., Lynn, H., Camp, S. M., Lussier, Y., Abraham, I., Carter, D., Miller, E. J., Mekontso-Dessap, A., Downs, C. A. & Garcia, J. G. N., Dec 16 2019, In : Critical Care. 23, 1, 410.

Research output: Contribution to journalArticle

Open Access
Adult Respiratory Distress Syndrome
Biomarkers
Mortality
Phenotype
Nicotinamide Phosphoribosyltransferase

Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells

Liu, P., Kerins, M. J., Tian, W., Neupane, D., Zhang, D. D. & Ooi, A., Jan 1 2019, In : Journal of Biological Chemistry. 294, 48, p. 18131-18149 19 p.

Research output: Contribution to journalArticle

Open Access
Antioxidant Response Elements
Genes
Cells
Chromatin Immunoprecipitation
Chromatin

Discovery of Influenza Polymerase PA-PB1 Interaction Inhibitors Using an in Vitro Split-Luciferase Complementation-Based Assay

Zhang, J., Hu, Y., Wu, N. & Wang, J., Jan 1 2019, (Accepted/In press) In : ACS Chemical Biology.

Research output: Contribution to journalArticle

Luciferases
Human Influenza
Antiviral Agents
Assays
Screening
1 Citation (Scopus)

Discovery of Quinoline Analogues as Potent Antivirals against Enterovirus D68 (EV-D68)

Musharrafieh, R., Zhang, J., Tuohy, P., Kitamura, N., Bellampalli, S. S., Hu, Y., Khanna, R. & Wang, J., Jan 1 2019, In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Enterovirus
Antiviral Agents
Dibucaine
Viral Cytopathogenic Effect
Structure-Activity Relationship

Diversity-Oriented Synthesis of Imidazo-Dipyridines with Anticancer Activity via the Groebke-Blackburn-Bienaymé and TBAB-Mediated Cascade Reaction in One Pot

Li, Y., Huang, J. H., Wang, J. L., Song, G. T., Tang, D. Y., Yao, F., Lin, H. K., Yan, W., Li, H. Y., Xu, Z. G. & Chen, Z. Z., Jan 1 2019, (Accepted/In press) In : Journal of Organic Chemistry.

Research output: Contribution to journalArticle

Phosphorylation
Cyclization
Scaffolds
Phosphotransferases
Metals

DNA methylation among firefighters

Zhou, J., Jenkins, T. G., Jung, A. M., Jeong, K. S., Zhai, J., Jacobs, E. T., Griffin, S., Dearmon-Moore, D., Littau, S. R., Peate, W. F., Ellis, N., Lance, M. P., Chen, Y. & Burgess, J. L., Mar 1 2019, In : PloS one. 14, 3, e0214282.

Research output: Contribution to journalArticle

Open Access
fire fighters
Firefighters
DNA methylation
DNA Methylation
Methylation

DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients

Vrba, L., Oshiro, M. M., Kim, S. S., Garland, L. L., Placencia, C., Mahadevan, D., Nelson, M. A. & Futscher, B. W., Jan 1 2019, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journalArticle

Open Access
DNA Methylation
Non-Small Cell Lung Carcinoma
Computer Simulation
Biomarkers
Biopsy

Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB)inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections

Washburn, A., Abdeen, S., Ovechkina, Y., Ray, A. M., Stevens, M., Chitre, S., Sivinski, J., Park, Y., Johnson, J., Hoang, Q. Q., Chapman, E., Parish, T. & Johnson, S. M., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Polypharmacology
Chaperonins
Mycobacterium Infections
Protein Tyrosine Phosphatases
Mycobacterium tuberculosis

Effectiveness and Tolerability of Vildagliptin and the Single Pill Combination of Vildagliptin and Metformin in “Real-World” Management of Type 2 Diabetes Mellitus: The G-FORCE Study

Van Gaal, L., Hermans, M. P., Daci, E., Denhaerynck, K., De Meester, L., MacDonald, K., Abraham, I. L., Vancayzeele, S. & Maris, M., Jun 1 2019, In : Diabetes Therapy. 10, 3, p. 965-979 15 p.

Research output: Contribution to journalArticle

Open Access
Metformin
Type 2 Diabetes Mellitus
Fasting
Glucose
Glycosylated Hemoglobin A

Effect of pH and Ionic Strength on the Solubility of Quinoline: Back-to-Basics

Carvajal, M. T. & Yalkowsky, S. H., Apr 1 2019, In : AAPS PharmSciTech. 20, 3, 124.

Research output: Contribution to journalArticle

quinoline
ionic strength
Osmolar Concentration
Solubility
solubility
Social Support
Self Care
Social Capital
Exercise
Education
2 Citations (Scopus)

Evaluation of Machine-Learning Algorithms for Predicting Opioid Overdose Risk Among Medicare Beneficiaries With Opioid Prescriptions

Lo-Ciganic, W. H., Huang, J. L., Zhang, H., Weiss, J. C., Wu, Y., Kwoh, C. K., Donohue, J. M., Cochran, G., Gordon, A. J., Malone, D. C., Kuza, C. C. & Gellad, W. F., Mar 1 2019, In : JAMA network open. 2, 3, p. e190968

Research output: Contribution to journalArticle

Medicare
Opioid Analgesics
Prescriptions
Sensitivity and Specificity
Machine Learning
1 Citation (Scopus)
Major Depressive Disorder
Antidepressive Agents
Dementia
Prescriptions
Doxepin