Research Output

2019

Antivenom effect on lymphatic absorption and pharmacokinetics of coral snake venom using a large animal model

Paniagua, D., Vergara, I., Román, R., Romero, C., Benard-Valle, M., Calderón, A., Jiménez, L., Bernas, M. J., Witte, M. H., Boyer, L. V. & Alagón, A., Aug 3 2019, In : Clinical Toxicology. 57, 8, p. 727-734 8 p.

Research output: Contribution to journalArticle

2017

A clinical trial protocol to treat massive Africanized honeybee (Apis mellifera) attack with a new apilic antivenom

Barbosa, A. N., Boyer, L. V., Chippaux, J. P., Medolago, N. B., Caramori, C. A., Paixão, A. G., Poli, J. P. V., Mendes, M. B., dos Santos, L. D., Ferreira, R. S. & Barraviera, B., Mar 16 2017, In : Journal of Venomous Animals and Toxins Including Tropical Diseases. 23, 1, 14.

Research output: Contribution to journalArticle

11 Scopus citations

The Bold and the Beautiful: a Neurotoxicity Comparison of New World Coral Snakes in the Micruroides and Micrurus Genera and Relative Neutralization by Antivenom

Yang, D. C., Dobson, J., Cochran, C., Dashevsky, D., Arbuckle, K., Benard, M., Boyer, L. V., Alagón, A., Hendrikx, I., Hodgson, W. C. & Fry, B. G., Oct 1 2017, In : Neurotoxicity Research. 32, 3, p. 487-495 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Biodistribution and lymphatic tracking of the main neurotoxin of micrurus fulvius venom by molecular imaging

Vergara, I., Castillo, E. Y., Romero-Piña, M. E., Torres-Viquez, I., Paniagua, D., Boyer, L. V., Alagón, A. & Medina, L. A., Mar 26 2016, In : Toxins. 8, 4, 85.

Research output: Contribution to journalArticle

4 Scopus citations

The Reply

Boyer, L. V., Jun 1 2016, In : American Journal of Medicine. 129, 6, p. e31

Research output: Contribution to journalLetter

8 Scopus citations

Venom yield and its relationship with body size and fang separation of pit vipers from Argentina

de Roodt, A. R., Boyer, L. V., Lanari, L. C., Irazu, L., Laskowicz, R. D., Sabattini, P. L. & Damin, C. F., Oct 1 2016, In : Toxicon. 121, p. 22-29 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Antivenom Research and Development: Evolution, Pathophysiology and Biodiscovery

Benard-Valle, M., Neri-Castro, E. E., Fry, B. G., Boyer, L., Cochran, C., Alam, M., Jackson, TNW., Paniagua, D., Olvera-Rodriguez, F., Koludarov, I., Sunagar, K. & Alagón, A., 2015, Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery. Fry, B. G. (ed.). New York: Oxford University Press, p. 61-72

Research output: Chapter in Book/Report/Conference proceedingChapter

Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial

Bush, S. P., Ruha, A. M., Seifert, S. A., Morgan, D. L., Lewis, B. J., Arnold, T. C., Clark, R. F., Meggs, W. J., Toschlog, E. A., Borron, S. W., Figge, G. R., Sollee, D. R., Shirazi, F. M., Wolk, R., De Chazal, I., Quan, D., García-Ubbelohde, W., Alagón, A., Gerkin, R. D. & Boyer, L. V., Jan 1 2015, In : Clinical Toxicology. 53, 1, p. 37-45 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Ineffective traditional and modern techniques for the treatment of snakebite: Evolution, Pathophysiology and Biodiscovery

Bénard-Valle, M., Neri-Castro, E. E., Boyer, L., Jackson, TNW., Sunagar, K., Clarkson, M. & Fry, B. G., 2015, Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery. Fry, B. G. (ed.). New York: Oxford University Press, p. 73-88

Research output: Chapter in Book/Report/Conference proceedingChapter

In Reply re: "Comparison of F(ab')2 versus Fab antivenom for Pit Viper Envenomation: A Prospective, Blinded, Multicenter, Randomized Clinical Trial"

Bush, S. P., Ruha, A. M., Seifert, S. A., Sollee, D. R. & Boyer, L. V., May 1 2015, In : Clinical Toxicology. 53, 4, p. 414-415 2 p.

Research output: Contribution to journalLetter

3 Scopus citations
11 Scopus citations

Maintaining venomous reptile collections: protocols and occupational safety: Evolution, Pathophysiology and Biodiscovery

Fry, B. G., Hendrikx, I., Rowley, P., Jackson, TNW., Van der Ploeg, H., Johnson, R., Sasa, M., Dunstan, N., Barve, S., Lock, B., Phillip, T., Zivkovic, M., Boyer, L., Wiley, K., Harrison, J., Carmichael, R., Morris, M. C., Brandl, D., Shankar, G., McCarthy, S. & 3 others, Sunagar, K., Pittman, J. & Cochran, C., 2015, Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery. Fry, B. G. (ed.). New York: Oxford University Press, p. 89-131

Research output: Chapter in Book/Report/Conference proceedingChapter

On 1000-fold pharmaceutical price markups and why drugs cost more in the United States than in Mexico

Boyer, L. V., Dec 1 2015, In : American Journal of Medicine. 128, 12, p. 1265-1267 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Post-exposure treatment of Ebola virus using passive immunotherapy: Proposal for a new strategy

Chippaux, J. P., Boyer, L. V. & Alagón, A., Feb 15 2015, In : Journal of Venomous Animals and Toxins Including Tropical Diseases. 21, 1, 3.

Research output: Contribution to journalReview article

3 Scopus citations

Signs, symptoms and treatment of envenomation: Evolution, Pathophysiology and Biodiscovery

Boyer, L., Alagón, A., Fry, B. G., Jackson, TNW., Sunagar, K. & Chippaux, J-P., 2015, Venomous Reptiles and their Toxins: Evolution, Pathophysiology and Biodiscovery. Fry, B. G. (ed.). 1st ed. New York: Oxford University Press, p. 32-60

Research output: Chapter in Book/Report/Conference proceedingChapter

Snake bites and antivenom shortage in Africa

Chippaux, J. P., Massougbodji, A., Diouf, A., Baldé, C. M. & Boyer, L. V., Dec 5 2015, In : The Lancet. 386, 10010, p. 2252-2253 2 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Erratum: Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental antivenoms (Toxicon (2014) 85 (31-45))

Lanari, L. C., Olvera, A., Costa De Oliveira, V., Laskowicz, R. D., Boyer, L., Lago, N. R., Alagón, A. & De Roodt, A. R., Sep 15 2014, In : Toxicon. 88, 1 p.

Research output: Contribution to journalComment/debate

Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental antivenoms

Lanari, L. C., Olvera, A., Costa De Oliveira, V., Laskowicz, R. D., Boyer, L., Lago, N. R., Alejandro, A. & De Roodt, A. R., Jul 2014, In : Toxicon. 85, p. 31-45 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Non-native (exotic) snake envenomations in the U.S., 2005-2011

Warrick, B. J., Boyer, L. V. & Seifert, S. A., Jan 1 2014, In : Toxins. 6, 10, p. 2899-2911 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Protein content of antivenoms and relationship with their immunochemical reactivity and neutralization assays

De Roodt, A. R., Clement, H., Dolab, J. A., Litwin, S., Hajos, S. E., Boyer, L. & Alagón, A., Jul 2014, In : Clinical Toxicology. 52, 6, p. 594-603 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Role of the lymphatic system on snake venom absorption: review of mechanism and clinical implications

Paniagua, D., Vergara, I., Boyer, L. & Alagón, A., 2014, Snake Venoms. Gopalakrishnakone, P., Inagaki, H., Mukherjee, A. K., Rahmy, T. R. & Vogel, C-W. (eds.). Netherlands: Springer

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Editorial: Scorpion venom and antivenom

Boyer, L., Dec 15 2013, In : Toxicon. 76, 1 p.

Research output: Contribution to journalEditorial

Effectiveness of Centruroides scorpion antivenom compared to historical controls

Boyer, L. V., Theodorou, A. A., Chase, P. B., Osnaya, N., Berg, M., Mallie, J., Carbajal, Y., De Jesus-Hernandez, T., Olvera, F. & Alagón, A., Dec 15 2013, In : Toxicon. 76, p. 377-385 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

History of scorpion antivenom: One Arizonan's view

Boyer, L., Jul 1 2013, In : Toxicon. 69, p. 14-20 7 p.

Research output: Contribution to journalReview article

8 Scopus citations

Is scorpion antivenom cost-effective as marketed in the United States?

Armstrong, E. P., Bakall, M., Skrepnek, G. H. & Boyer, L. V., Dec 15 2013, In : Toxicon. 76, p. 394-398 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Safety of intravenous equine F(ab')2: Insights following clinical trials involving 1534 recipients of scorpion antivenom

Boyer, L., Degan, J., Ruha, A. M., Mallie, J., Mangin, E. & Alagón, A., Dec 15 2013, In : Toxicon. 76, p. 386-393 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Subacute coagulopathy in a randomized, comparative trial of Fab and F(ab')2 antivenoms

Boyer, L. V., Chase, P. B., Degan, J. A., Figge, G., Buelna-Romero, A., Luchetti, C. & Alagón, A., Nov 2013, In : Toxicon. 74, p. 101-108 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
2012

Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep

Paniagua, D., Jiménez, L., Romero, C., Vergara, I., Calderón, A., Benard, M., Bernas, M. J., Rilo, H., De Roodt, A., D'Suze, G., Witte, M. H., Boyer, L. V. & Alagón, A., Dec 2012, In : Lymphology. 45, 4, p. 144-153 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Spider Bite: Management of Wilderness and Environmental Emergen

Boyer, L., Binford, G. & Degan, J., 2011, Wilderness Medicine: Management of Wilderness and Environmental Emergen. Auerbach, P. (ed.). 6th ed. St. Louis: Mosby, p. 975-996

Research output: Chapter in Book/Report/Conference proceedingChapter

2010

Editorial

Boyer, L., Nov 1 2010, In : International immunopharmacology. 10, 11, 1 p.

Research output: Contribution to journalEditorial

1 Scopus citations

International Immunopharmacology. Editorial.

Boyer, L., Nov 1 2010, In : International immunopharmacology. 10, 11, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Scorpion antivenom administered by alternative infusions

Hiller, K., Jarrod, M. M., Franke, H. A., Degan, J., Boyer, L. V. & Fox, F. M., Sep 1 2010, In : Annals of emergency medicine. 56, 3, p. 309-310 2 p.

Research output: Contribution to journalLetter

2 Scopus citations

The 3 + 3 dose escalation design is not appropriate for antivenom dose finding

Chippaux, J. P. & Boyer, L., Jun 1 2010, In : Toxicon. 55, 7, p. 1408-1409 2 p.

Research output: Contribution to journalLetter

2 Scopus citations
2009

AAPCC database characterization of native U.S. venomous snake exposures, 2001-2005

Seifert, S. A., Boyer, L. V., Benson, B. E. & Rogers, J. J., Nov 4 2009, In : Clinical Toxicology. 47, 4, p. 327-335 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Antivenom for critically ill children with neurotoxicity from scorpion stings

Boyer, L. V., Theodorou, A. A., Berg, R. A., Mallie, J., Chávez-Méndez, A., García-Ubbelohde, W., Hardiman, S. & Alagón, A., May 14 2009, In : New England Journal of Medicine. 360, 20, p. 2090-2098 9 p.

Research output: Contribution to journalArticle

105 Scopus citations

Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients

Chase, P., Boyer-Hassen, L., Mcnally, J., Vazquez, H. L., Theodorou, A. A., Walter, F. G. & Alagon, A., Feb 1 2009, In : Clinical Toxicology. 47, 1, p. 24-28 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

The authors reply

Boyer, L., Alagón, A. & Theodorou, A., Aug 6 2009, In : New England Journal of Medicine. 361, 6, 1 p.

Research output: Contribution to journalLetter

2 Scopus citations
2008

Toxicologic Information Resources for Reptile Envenomations

McNally, J., Boesen, K. & Boyer, L., May 1 2008, In : Veterinary Clinics of North America - Exotic Animal Practice. 11, 2, p. 389-401 13 p.

Research output: Contribution to journalReview article

7 Scopus citations
2007

Toxic Exposure Surveillance System (TESS)-based characterization of U.S. non-native venomous snake exposures, 1995-2004

Seifert, S. A., Oakes, J. A. & Boyer, L. V., Jul 1 2007, In : Clinical Toxicology. 45, 5, p. 571-578 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2006

Resistance of antivenom proteins to foaming-induced denaturation

Kanavage, A. D., Boyer, L. V., McNally, J. & Osterhout, J. J., Mar 15 2006, In : Toxicon. 47, 4, p. 445-452 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Spider Bite: Management of Wilderness and Environmental Emergen

Boyer, L., Binford, G. & McNally, J., 2006, Wilderness Medicine: Management of Wilderness and Environmental Emergen. Auerbach, P. (ed.). 5th ed. St. Louis: Mosby

Research output: Chapter in Book/Report/Conference proceedingChapter

2005

Understanding the Hazards: Toxicity and Safety: A Museum Resource for Managing Contaminated Cultur

Boyer, L. V., Seifert, S., Odegaard, N., Pool, M. & Burroughs, G. E., 2005, Old Poisons, new Problems: A Museum Resource for Managing Contaminated Cultur. Odegaard, N. & Sadongei, A. (eds.). AltaMira Press, div of Rowman & Littlefield Publishers, Inc, p. 73-84

Research output: Chapter in Book/Report/Conference proceedingChapter

2004

Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing

Valdez-Cruz, N. A., Dávila, S., Licea, A., Corona, M., Zamudio, F. Z., García-Valdes, J., Boyer, L. V. & Possani, L. D., Jun 2004, In : Biochimie. 86, 6, p. 387-396 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Lead

Dart, R., Hurlbut, K. & Boyer, L. V., 2004, Medical Toxicology. Dart, R. (ed.). Philadelphia: Lippincott Williams & Wilkins, p. 1423-1431

Research output: Chapter in Book/Report/Conference proceedingChapter

Scorpion Envenomation

Boyer, L. V., 2004, Medical Toxicology. Dart, R. (ed.). 3rd ed. Philadelphia: Lippincott Williams & Wilkins, p. 1603-1605

Research output: Chapter in Book/Report/Conference proceedingChapter

2003

New Ideas for the Testing, Documentation, and Storage of Objects Previously Treated with Pesticides

Odegaard, N., Boyer, L., Huber, M. J., Kaplan, L., Kunioka, C., Moreno, T., Sadongei, A., Smith, D. R. & Zimmt, W., 2003, In : Objects Specialty Group Postprints. 10, p. 33-42

Research output: Contribution to journalArticle

Poison center medical error detection and prevention

Seifert, S. A., Boyer, L. V., Bronstein, A. C., Jacobitz, K. & McNally, J., 2003, In : Journal of Toxicology: Clinical Toxicology. 41, p. 685-686

Research output: Contribution to journalArticle