Research Output 1991 2019

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2019

Antivenom effect on lymphatic absorption and pharmacokinetics of coral snake venom using a large animal model

Paniagua, D., Vergara, I., Román, R., Romero, C., Benard-Valle, M., Calderón, A., Jiménez, L., Bernas, M. J., Witte, M. H., Boyer, L. V. & Alagón, A., Aug 3 2019, In : Clinical Toxicology. 57, 8, p. 727-734 8 p.

Research output: Contribution to journalArticle

Antivenins
Elapidae
Snake Venoms
Pharmacokinetics
Venoms
2017
8 Citations (Scopus)

A clinical trial protocol to treat massive Africanized honeybee (Apis mellifera) attack with a new apilic antivenom

Barbosa, A. N., Boyer, L. V., Chippaux, J. P., Medolago, N. B., Caramori, C. A., Paixão, A. G., Poli, J. P. V., Mendes, M. B., dos Santos, L. D., Ferreira, R. S. & Barraviera, B., Mar 16 2017, In : Journal of Venomous Animals and Toxins Including Tropical Diseases. 23, 1, 14.

Research output: Contribution to journalArticle

antivenoms
Antivenins
Bees
Bites and Stings
Clinical Protocols
7 Citations (Scopus)

The Bold and the Beautiful: a Neurotoxicity Comparison of New World Coral Snakes in the Micruroides and Micrurus Genera and Relative Neutralization by Antivenom

Yang, D. C., Dobson, J., Cochran, C., Dashevsky, D., Arbuckle, K., Benard, M., Boyer, L. V., Alagón, A., Hendrikx, I., Hodgson, W. C. & Fry, B. G., Oct 1 2017, In : Neurotoxicity Research. 32, 3, p. 487-495 9 p.

Research output: Contribution to journalArticle

Antivenins
Elapidae
Venoms
Snake Bites
2016
4 Citations (Scopus)

Biodistribution and lymphatic tracking of the main neurotoxin of micrurus fulvius venom by molecular imaging

Vergara, I., Castillo, E. Y., Romero-Piña, M. E., Torres-Viquez, I., Paniagua, D., Boyer, L. V., Alagón, A. & Medina, L. A., Mar 26 2016, In : Toxins. 8, 4, 85.

Research output: Contribution to journalArticle

Molecular imaging
Molecular Imaging
Neurotoxins
Acetic Acid
Elapidae
Crotalid Venoms
Viper Venoms
Antivenins
Snake Bites
Immunoglobulin Fab Fragments
7 Citations (Scopus)
Bothrops
Crotalus
Venoms
Thrombin
Viper Venoms
3 Citations (Scopus)

Venom yield and its relationship with body size and fang separation of pit vipers from Argentina

de Roodt, A. R., Boyer, L. V., Lanari, L. C., Irazu, L., Laskowicz, R. D., Sabattini, P. L. & Damin, C. F., Oct 1 2016, In : Toxicon. 121, p. 22-29 8 p.

Research output: Contribution to journalArticle

Argentina
Venoms
Body Size
Punctures
Snakes
2015
29 Citations (Scopus)

Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial

Bush, S. P., Ruha, A. M., Seifert, S. A., Morgan, D. L., Lewis, B. J., Arnold, T. C., Clark, R. F., Meggs, W. J., Toschlog, E. A., Borron, S. W., Figge, G. R., Sollee, D. R., Shirazi, F., Wolk, R., De Chazal, I., Quan, D., García-Ubbelohde, W., Alagón, A., Gerkin, R. D. & Boyer, L. V., Jan 1 2015, In : Clinical Toxicology. 53, 1, p. 37-45 9 p.

Research output: Contribution to journalArticle

Antivenins
Randomized Controlled Trials
Placebos
Half-Life
Maintenance
3 Citations (Scopus)
Crotalus
Venoms
Fibrinolysis
Tissue Plasminogen Activator
Carbon Monoxide
11 Citations (Scopus)
Crotalus
Venoms
Carbon Monoxide
Iron
Antivenins
9 Citations (Scopus)

On 1000-fold pharmaceutical price markups and why drugs cost more in the United States than in Mexico

Boyer, L. V., Dec 1 2015, In : American Journal of Medicine. 128, 12, p. 1265-1267 3 p.

Research output: Contribution to journalArticle

Government Financing
Antivenins
Drug Costs
Drug Industry
Mexico
3 Citations (Scopus)
Ebolavirus
Passive Immunization
immunotherapy
Viruses
Ebola Hemorrhagic Fever
6 Citations (Scopus)

Snake bites and antivenom shortage in Africa

Chippaux, J. P., Massougbodji, A., Diouf, A., Baldé, C. M. & Boyer, L. V., Dec 5 2015, In : The Lancet. 386, 10010, p. 2252-2253 2 p.

Research output: Contribution to journalArticle

Drug Utilization
Antivenins
Snake Bites
Health Services Accessibility
Africa South of the Sahara
2014

Erratum: Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental antivenoms (Toxicon (2014) 85 (31-45))

Lanari, L. C., Olvera, A., Costa De Oliveira, V., Laskowicz, R. D., Boyer, L. V., Lago, N. R., Alagón, A. & De Roodt, A. R., Sep 15 2014, In : Toxicon. 88, p. 138 1 p.

Research output: Contribution to journalArticle

Bothrops
Antivenins
Venoms
3 Citations (Scopus)

Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental antivenoms

Lanari, L. C., Olvera, A., Costa De Oliveira, V., Laskowicz, R. D., Boyer, L. V., Lago, N. R., Alejandro, A. & De Roodt, A. R., 2014, In : Toxicon. 85, p. 31-45 15 p.

Research output: Contribution to journalArticle

Bothrops
Antivenins
Venoms
Snake Venoms
Poisons
9 Citations (Scopus)

Non-native (exotic) snake envenomations in the U.S., 2005-2011

Warrick, B. J., Boyer, L. V. & Seifert, S. A., 2014, In : Toxins. 6, 10, p. 2899-2911 13 p.

Research output: Contribution to journalArticle

Coding errors
Antivenins
Snake Bites
Poisons
Snakes
4 Citations (Scopus)

Protein content of antivenoms and relationship with their immunochemical reactivity and neutralization assays

De Roodt, A. R., Clement, H., Dolab, J. A., Litwin, S., Hajos, S. E., Boyer, L. V. & Alagón, A., 2014, In : Clinical Toxicology. 52, 6, p. 594-603 10 p.

Research output: Contribution to journalArticle

Antivenins
Assays
Proteins
Venoms
Crotalid Venoms
2013

Editorial: Scorpion venom and antivenom

Boyer, L. V., Dec 15 2013, In : Toxicon. 76, p. 327 1 p.

Research output: Contribution to journalArticle

Scorpion Venoms
Antivenins
9 Citations (Scopus)

Effectiveness of Centruroides scorpion antivenom compared to historical controls

Boyer, L. V., Theodorou, A. A., Chase, P. B., Osnaya, N., Berg, M., Mallie, J., Carbajal, Y., De Jesus-Hernandez, T., Olvera, F. & Alagón, A., Dec 15 2013, In : Toxicon. 76, p. 377-385 9 p.

Research output: Contribution to journalArticle

Antivenins
Scorpions
Placebos
Intensive care units
Midazolam
8 Citations (Scopus)

History of scorpion antivenom: One Arizonan's view

Boyer, L. V., Jul 2013, In : Toxicon. 69, p. 14-20 7 p.

Research output: Contribution to journalArticle

Antivenins
Scorpions
Venoms
Ancient History
History
16 Citations (Scopus)

Is scorpion antivenom cost-effective as marketed in the United States?

Armstrong, E. P., Bakall, M., Skrepnek, G. H. & Boyer, L. V., Dec 15 2013, In : Toxicon. 76, p. 394-398 5 p.

Research output: Contribution to journalArticle

Antivenins
Scorpions
Costs and Cost Analysis
Costs
Medicaid
24 Citations (Scopus)

Safety of intravenous equine F(ab')2: Insights following clinical trials involving 1534 recipients of scorpion antivenom

Boyer, L. V., Degan, J., Ruha, A. M., Mallie, J., Mangin, E. & Alagón, A., Dec 15 2013, In : Toxicon. 76, p. 386-393 8 p.

Research output: Contribution to journalArticle

Antivenins
Scorpions
Antigen-antibody reactions
Horses
Clinical Trials
24 Citations (Scopus)

Subacute coagulopathy in a randomized, comparative trial of Fab and F(ab')2 antivenoms

Boyer, L. V., Chase, P. B., Degan, J. A., Figge, G., Buelna-Romero, A., Luchetti, C. & Alagón, A., Nov 2013, In : Toxicon. 74, p. 101-108 8 p.

Research output: Contribution to journalArticle

Antivenins
Venoms
Coagulation
Platelets
Fibrinogen
2012
18 Citations (Scopus)

Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep

Paniagua, D., Jiménez, L., Romero, C., Vergara, I., Calderón, A., Benard, M., Bernas, M. J., Rilo, H., De Roodt, A., D'Suze, G., Witte, M. H., Boyer, L. V. & Alagón, A., Dec 2012, In : Lymphology. 45, 4, p. 144-153 10 p.

Research output: Contribution to journalArticle

Elapidae
Snake Venoms
Venoms
Lymph
Thoracic Duct
2010
1 Citation (Scopus)

Editorial

Boyer, L. V., Nov 2010, In : International Immunopharmacology. 10, 11, p. 1317 1 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Scorpion antivenom administered by alternative infusions

Hiller, K. M., Jarrod, M. M., Franke, H. A., Degan, J., Boyer, L. V. & Fox, F. M., Sep 2010, In : Annals of Emergency Medicine. 56, 3, p. 309-310 2 p.

Research output: Contribution to journalArticle

Intraosseous Infusions
Scorpion Stings
Spider Bites
Scorpion Venoms
Antivenins
2 Citations (Scopus)

The 3 + 3 dose escalation design is not appropriate for antivenom dose finding

Chippaux, J. P. & Boyer, L. V., Jun 2010, In : Toxicon. 55, 7, p. 1408-1409 2 p.

Research output: Contribution to journalArticle

Drug Dose Response Relationship
Antivenins
Snake Bites
Maximum Tolerated Dose
Research Design
2009
46 Citations (Scopus)

AAPCC database characterization of native U.S. venomous snake exposures, 2001-2005

Seifert, S. A., Boyer, L. V., Benson, B. E. & Rogers, J. J., 2009, In : Clinical Toxicology. 47, 4, p. 327-335 9 p.

Research output: Contribution to journalArticle

Agkistrodon
Crotalus
Snakes
Poisons
Databases
105 Citations (Scopus)

Antivenom for critically ill children with neurotoxicity from scorpion stings

Boyer, L. V., Theodorou, A. A., Berg, R. A., Mallie, J., Chávez-Méndez, A., García-Ubbelohde, W., Hardiman, S. & Alagón, A., May 14 2009, In : New England Journal of Medicine. 360, 20, p. 2090-2098 9 p.

Research output: Contribution to journalArticle

Scorpion Stings
Antivenins
Scorpions
Critical Illness
Placebos
13 Citations (Scopus)

Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients

Chase, P., Boyer, L. V., Mcnally, J., Vazquez, H. L., Theodorou, A. A., Walter, F. G. & Alagon, A., Feb 2009, In : Clinical Toxicology. 47, 1, p. 24-28 5 p.

Research output: Contribution to journalArticle

Venoms
Urine
Serum
Immunosorbents
Assays
2 Citations (Scopus)

The authors reply

Boyer, L. V., Alagón, A. & Theodorou, A. A., Aug 6 2009, In : New England Journal of Medicine. 361, 6, p. 632 1 p.

Research output: Contribution to journalArticle

2008
7 Citations (Scopus)

Toxicologic Information Resources for Reptile Envenomations

McNally, J., Boesen, K. J. & Boyer, L. V., May 2008, In : Veterinary Clinics of North America - Exotic Animal Practice. 11, 2, p. 389-401 13 p.

Research output: Contribution to journalArticle

Reptiles
information sources
reptiles
snakes
Snake Bites
2007
11 Citations (Scopus)

Toxic Exposure Surveillance System (TESS)-based characterization of U.S. non-native venomous snake exposures, 1995-2004

Seifert, S. A., Oakes, J. A. & Boyer, L. V., Jul 2007, In : Clinical Toxicology. 45, 5, p. 571-578 8 p.

Research output: Contribution to journalArticle

Snakes
Poisons
Databases
Antivenins
Intensive care units
2006
6 Citations (Scopus)

Resistance of antivenom proteins to foaming-induced denaturation

Kanavage, A. D., Boyer, L. V., McNally, J. & Osterhout, J. J., Mar 15 2006, In : Toxicon. 47, 4, p. 445-452 8 p.

Research output: Contribution to journalArticle

Antivenins
Denaturation
Proteins
Protein Unfolding
Protein Refolding
2004
28 Citations (Scopus)

Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing

Valdez-Cruz, N. A., Dávila, S., Licea, A., Corona, M., Zamudio, F. Z., García-Valdes, J., Boyer, L. V. & Possani, L. D., Jun 2004, In : Biochimie. 86, 6, p. 387-396 10 p.

Research output: Contribution to journalArticle

Scorpions
Venoms
Molecular Biology
Wood
Genes
2003

New Ideas for the Testing, Documentation, and Storage of Objects Previously Treated with Pesticides

Odegaard, N., Boyer, L., Huber, M. J., Kaplan, L., Kunioka, C., Moreno, T., Sadongei, A., Smith, D. R. & Zimmt, W., 2003, In : Objects Specialty Group Postprints. 10, p. 33-42

Research output: Contribution to journalArticle

Poison center medical error detection and prevention

Seifert, S. A., Boyer, L. V., Bronstein, A. C., Jacobitz, K. & McNally, J., 2003, In : Journal of Toxicology: Clinical Toxicology. 41, p. 685-686

Research output: Contribution to journalArticle

2002

Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients

Chase, P. B., Vazquez, H. L., Boyer, L. V., Theodorou, A. A., Walter, F. G. & Alagón, A., 2002, In : Journal of Toxicology: Clinical Toxicology. 40, p. 650

Research output: Contribution to journalArticle

2001
30 Citations (Scopus)

A randomized Multicenter Trial of Crotalinae polyvalent immune Fab (ovine) antivenom for the treatment for crotaline snakebite in the United States

Dart, R. C., Seifert, S. A., Boyer, L. V., Clark, R. F., Hall, E., McKinney, P., McNally, J., Kitchens, C. S., Curry, S. C., Bogdan, G. M., Ward, S. B. & Porter, R. S., Sep 10 2001, In : Archives of Internal Medicine. 161, 16, p. 2030-2036 7 p.

Research output: Contribution to journalArticle

Antivenins
Snake Bites
Multicenter Studies
Sheep
Therapeutics

Death from Centruroides scorpion sting allergy

Boyer, L., Heubner, B. L., McNally, J. & Buchanan, J., 2001, In : Clinical Toxicology. 39, p. 561

Research output: Contribution to journalArticle

79 Citations (Scopus)
Antivenins
Snake Bites
Passive Immunization
Guidelines
Recurrence
79 Citations (Scopus)
Antivenins
Snake Bites
Passive Immunization
Venoms
Immunoglobulins
2000
8 Citations (Scopus)

Arsenic contamination of museum artifacts repatriated to a native American tribe [5]

Seifert, S. A., Boyer, L. V., Odegaard, N. N., Smith, D. R. & Dongoske, K. E., May 31 2000, In : Journal of the American Medical Association. 283, 20, p. 2658-2659 2 p.

Research output: Contribution to journalArticle

Museums
North American Indians
Arsenic
Population Groups
Pesticides
39 Citations (Scopus)

Mercury toxicity due to use of a cosmetic cream

McRill, C., Boyer, L. V., Flood, T. J. & Ortega, L., Jan 2000, In : Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine. 42, 1, p. 4-7 4 p.

Research output: Contribution to journalArticle

Mercury
Cosmetics
Urine
Health Services
Beauty
1999

Neutralization of Agkistrodon saxatilis (Gloydius saxatilis) venom with CroTab® in a murine model

McNally, J., Boyer, L., Hare, T., Consroe, P. & McClure, T., 1999, In : Clinical Toxicology. 37, p. 668

Research output: Contribution to journalArticle

Prevention and treatment of recurrent local symptoms in Crotalid envenomation treated with Ovine Fab

Seifert, S. A., Dart, R. C., Boyer, L. V., Hall, E. L., Kitchens, C. S., Bogdan, G. M. & McNally, J., 1999, In : Clinical Toxicology. 37, p. 668

Research output: Contribution to journalArticle

90 Citations (Scopus)

Recurrent and persistent coagulopathy following pit viper envenomation

Boyer, L. V., Seifert, S. A., Clark, R. F., McNally, J. T., Williams, S. R., Nordt, S. P., Walter, F. G. & Dart, R. C., Apr 12 1999, In : Archives of Internal Medicine. 159, 7, p. 706-710 5 p.

Research output: Contribution to journalArticle

Antivenins
Snake Bites
Fibrin
Thrombocytopenia
Clinical Trials
1998
8 Citations (Scopus)

Chaparral-induced hepatotoxicity

Grant, K. L., Boyer, L. V. & Erdman, B. E., Mar 1998, In : Integrative Medicine. 1, 2, p. 83-87 5 p.

Research output: Contribution to journalArticle

Hepatitis
Liver
Larrea
Chemical and Drug Induced Liver Injury
Lignans