• 4459 Citations
  • 32 h-Index
1982 …2020

Research output per year

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Research Output

2020

Challenges in dosimetry and radiation dose trends

Karellas, A., 2020, In : Radiology. 294, 2, p. 360-361 2 p.

Research output: Contribution to journalComment/debate

Cone-beam breast computed tomography using ultra-fast image reconstruction with constrained, total-variation minimization for suppression of artifacts

Tseng, H. W., Vedantham, S. & Karellas, A., May 2020, In : Physica Medica. 73, p. 117-124 8 p.

Research output: Contribution to journalArticle

Dedicated cone-beam breast CT using laterally-shifted detector geometry: Quantitative analysis of feasibility for clinical translation

Vedantham, S., Tseng, H. W., Konate, S., Shi, L. & Karellas, A., 2020, In : Journal of X-Ray Science and Technology. 28, 3, p. 405-426 22 p.

Research output: Contribution to journalArticle

2019

Investigation of transmission computed tomography (CT) image quality and x-ray dose achievable from an experimental dual-mode benchtop x-ray fluorescence CT and transmission CT system

Deng, L., Yasar, S., Ahmed, M. F., Jayarathna, S., Feng, P., Wei, B., Vedantham, S., Karellas, A. & Cho, S. H., 2019, In : Journal of X-Ray Science and Technology. 27, 3, p. 431-442 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Emerging Breast Imaging Technologies on the Horizon

Vedantham, S. & Karellas, A., Feb 2018, In : Seminars in Ultrasound, CT and MRI. 39, 1, p. 114-121 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Newer Technologies in Breast Cancer Imaging: Dedicated Cone-Beam Breast Computed Tomography

O'Connell, A. M., Karellas, A., Vedantham, S. & Kawakyu-O'Connor, D. T., Feb 2018, In : Seminars in Ultrasound, CT and MRI. 39, 1, p. 106-113 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

The role of off-focus radiation in scatter correction for dedicated cone beam breast CT

Shi, L., Vedantham, S., Karellas, A. & Zhu, L., Jan 2018, In : Medical physics. 45, 1, p. 191-201 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

A framework for optimizing micro-CT in dual-modality micro-CT/XFCT small-animal imaging system

Vedantham, S., Shrestha, S., Karellas, A. & Cho, S. H., 2017, Radiation Detectors in Medicine, Industry, and National Security XVIII. Grim, G. P., Furenlid, L. R. & Barber, H. B. (eds.). SPIE, 103930R. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 10393).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Reduced patient radiation exposure during neurodiagnostic and interventional X-ray angiography with a new imaging platform

Van Der Marel, K., Vedantham, S., Van Der Bom, I. M. J., Howk, M., Narain, T., Ty, K., Karellas, A., Gounis, M. J., Puri, A. S. & Wakhloo, A. K., Mar 2017, In : American Journal of Neuroradiology. 38, 3, p. 442-449 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Scintillator performance considerations for dedicated breast computed tomography

Vedantham, S., Shi, L. & Karellas, A., 2017, Radiation Detectors in Medicine, Industry, and National Security XVIII. Grim, G. P., Furenlid, L. R. & Barber, H. B. (eds.). SPIE, 103930M. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 10393).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations
1 Scopus citations

X-ray scatter correction for dedicated cone beam breast CT using a forwardprojection model

Shi, L., Vedantham, S., Karellas, A. & Zhu, L., Jun 1 2017, In : Medical physics. 44, 6, p. 2312-2319 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Breast cancer margin detection with a single frequency terahertz imaging system

Yngvesson, S. K., Karellas, A., Glick, S., Khan, A., Siqueira, P. R., Kelly, P. A. & Peter, B., Jan 1 2016, Optical Interactions with Tissue and Cells XXVII. Jansen, E. D. (ed.). SPIE, 970603. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9706).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Effects of breast density and compression on normal breast tissue hemodynamics through breast tomosynthesis guided near-infrared spectral tomography

Michaelsen, K. E., Krishnaswamy, V., Shi, L., Vedantham, S., Karellas, A., Pogue, B. W., Paulsen, K. D. & Poplack, S. P., Sep 1 2016, In : Journal of biomedical optics. 21, 9, 091316.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Library-based scatter correction for dedicated cone beam breast CT: A feasibility study

Shi, L., Vedantham, S., Karellas, A. & Zhu, L., Jan 1 2016, Medical Imaging 2016: Physics of Medical Imaging. Kontos, D., Lo, J. Y. & Flohr, T. G. (eds.). SPIE, 978330. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9783).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Library based x-ray scatter correction for dedicated cone beam breast CT

Shi, L., Vedantham, S., Karellas, A. & Zhu, L., Aug 1 2016, In : Medical physics. 43, 8, p. 4529-4544 16 p.

Research output: Contribution to journalArticle

15 Scopus citations

Photon-counting hexagonal pixel array CdTe detector: Spatial resolution characteristics for image-guided interventional applications

Vedantham, S., Shrestha, S., Karellas, A., Shi, L., Gounis, M. J., Bellazzini, R., Spandre, G., Brez, A. & Minuti, M., May 1 2016, In : Medical physics. 43, 5, p. 2118-2130 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Prototypes of self-powered radiation detectors employing intrinsic high-energy current

Zygmanski, P., Shrestha, S., Briovio, D., Karellas, A. & Sajo, E., Jan 1 2016, In : Medical physics. 43, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

A novel cyber physical system for 3-D imaging of the small intestine in vivo

Pahlavan, K., Geng, Y., Cave, D. R., Bao, G., Ml, L., Agu, E., Karellas, A., Sayrafian, K. & Tarokh, V., Dec 11 2015, In : IEEE Access. 3, p. 2730-2742 13 p., 7353114.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Calibration and optimization of 3D digital breast tomosynthesis guided near infrared spectral tomography

Michaelsen, K. E., Krishnaswamy, V., Shi, L., Vedantham, S., Poplack, S. P., Karellas, A., Pogue, B. W. & Paulsen, K. D., Nov 19 2015, In : Biomedical Optics Express. 6, 12, p. 4981-4991 11 p., 250601.

Research output: Contribution to journalArticle

9 Scopus citations

Digital breast tomosynthesis: State of the art1

Vedantham, S., Karellas, A., Vijayaraghavan, G. R. & Kopans, D. B., Dec 2015, In : Radiology. 277, 3, p. 663-684 22 p.

Research output: Contribution to journalArticle

87 Scopus citations

Digital breast tomosynthesis guided near infrared spectroscopy: Volumetric estimates of fibroglandular fraction and breast density from tomosynthesis reconstructions

Vedantham, S., Shi, L., Michaelsen, K. E., Krishnaswamy, V., Pogue, B. W., Poplack, S. P., Karellas, A. & Paulsen, K. D., Oct 27 2015, In : Biomedical Physics and Engineering Express. 1, 4, 045202.

Research output: Contribution to journalArticle

7 Scopus citations

Dosimetric properties of high energy current (HEC) detector in keV x-ray beams

Zygmanski, P., Shrestha, S., Elshahat, B., Karellas, A. & Sajo, E., Apr 7 2015, In : Physics in medicine and biology. 60, 7, p. N121-N129

Research output: Contribution to journalArticle

10 Scopus citations

Introduction: Advances and trends in image formation in X-ray computed tomography

Noo, F. & Karellas, A., May 1 2015, In : Medical physics. 42, 5, 1 p.

Research output: Contribution to journalEditorial

Monte Carlo simulation of a prototypical patient dosimetry system for fluoroscopic procedures

Goertz, L., Tsiamas, P., Karellas, A., Sajo, E. & Zygmanski, P., Aug 7 2015, In : Physics in medicine and biology. 60, 15, p. 5891-5909 19 p.

Research output: Contribution to journalArticle

4 Scopus citations

Radiologic image formation: Physical principles, technology, and radiation dose considerations

Karellas, A. & Vedantham, S., Jan 1 2015, Diagnostic Imaging of Child Abuse. Cambridge University Press, p. 667-687 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Technical Note: Nanometric organic photovoltaic thin film detectors for dose monitoring in diagnostic x-ray imaging

Elshahat, B., Gill, H. S., Filipyev, I., Shrestha, S., Hesser, J., Kumar, J., Karellas, A., Zygmanski, P. & Sajo, E., Jul 1 2015, In : Medical physics. 42, 7, p. 4027-4032 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

Jon, A. F., Cheema, A. R., Khan, A. N., Raptopoulos, V., Hauser, T., Nasser, I., Welty, F. K., Karellas, A. & Clouse, M. E., May 2014, In : Clinical Imaging. 38, 3, p. 259-264 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Computerized 3-dimensional localization of a video capsule in the abdominal cavity: Validation by digital radiography

Marya, N., Karellas, A., Foley, A., Roychowdhury, A. & Cave, D., Apr 2014, In : Gastrointestinal endoscopy. 79, 4, p. 669-674 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Feasibility of small animal anatomical and functional imaging with neutrons: A Monte Carlo simulation study

Medich, D. C., Currier, B. H. & Karellas, A., Oct 1 2014, In : IEEE Transactions on Nuclear Science. 61, 5, p. 2480-2488 9 p., 2334593.

Research output: Contribution to journalArticle

Large-angle x-ray scatter in Talbot-Lau interferometry for breast imaging

Vedantham, S., Shi, L. & Karellas, A., Nov 7 2014, In : Physics in medicine and biology. 59, 21, p. 6387-6400 14 p., 6387.

Research output: Contribution to journalArticle

9 Scopus citations

The potential role of dedicated 3D breast CT as a diagnostic tool: Review and early clinical examples

O'Connell, A. M., Karellas, A. & Vedantham, S., Nov 1 2014, In : Breast Journal. 20, 6, p. 592-605 14 p.

Research output: Contribution to journalArticle

40 Scopus citations
2013

ACR-AAPM-SIIM practice guideline for determinants of image quality in digital mammography

Kanal, K. M., Krupinski, E., Berns, E. A., Geiser, W. R., Karellas, A., Mainiero, M. B., Martin, M. C., Patel, S. B., Rubin, D. L., Shepard, J. D., Siegel, E. L., Wolfman, J. A., Mian, T. A., Mahoney, M. C. & Wyatt, M., Feb 2013, In : Journal of Digital Imaging. 26, 1, p. 10-25 16 p.

Research output: Contribution to journalReview article

19 Scopus citations

Dedicated breast CT: Geometric design considerations to maximize posterior breast coverage

Vedantham, S., Karellas, A., Emmons, M. M., Moss, L. J., Hussain, S. & Baker, S. P., Jun 21 2013, In : Physics in medicine and biology. 58, 12, p. 4099-4118 20 p.

Research output: Contribution to journalArticle

9 Scopus citations

Development and testing of a single frequency terahertz imaging system for breast cancer detection

St Peter, B., Yngvesson, S., Siqueira, P., Kelly, P., Khan, A., Glick, S. & Karellas, A., 2013, In : IEEE Journal of Biomedical and Health Informatics. 17, 4, p. 785-797 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Development and testing of a single frequency terahertz imaging system for breast cancer detection

Peter, B. S., Yngvesson, S., Siqueira, P., Kelly, P., Khan, A., Glick, S. & Karellas, A., Jul 2013, In : IEEE Transactions on Terahertz Science and Technology. 3, 4, p. 374-386 13 p., 6468149.

Research output: Contribution to journalArticle

10 Scopus citations

Estimating the effective radiation dose imparted to patients by intraoperative cone-beam computed tomography in thoracolumbar spinal surgery

Lange, J., Karellas, A., Street, J., Eck, J. C., Lapinsky, A., Connolly, P. J. & Dipaola, C. P., Mar 1 2013, In : Spine. 38, 5, p. E306-E312

Research output: Contribution to journalArticle

32 Scopus citations

Focus series introduction

Noo, F. & Karellas, A., Mar 2013, In : Medical physics. 40, 3, 031001.

Research output: Contribution to journalEditorial

Personalized estimates of radiation dose from dedicated breast CT in a diagnostic population and comparison with diagnostic mammography

Vedantham, S., Shi, L., Karellas, A., O'Connell, A. M. & Conover, D. L., Nov 21 2013, In : Physics in medicine and biology. 58, 22, p. 7921-7936 16 p.

Research output: Contribution to journalArticle

25 Scopus citations

Scaling-law for the energy dependence of anatomic power spectrum in dedicated breast CT

Vedantham, S., Shi, L., Glick, S. J. & Karellas, A., Jan 2013, In : Medical physics. 40, 1, 011901.

Research output: Contribution to journalArticle

12 Scopus citations

Stereoscopic digital mammography: Improved specificity and reduced rate of recall in a prospective clinical trial

D'Orsi, C. J., Getty, D. J., Pickett, R. M., Sechopoulos, I., Newell, M. S., Gundry, K. R., Bates, S. R., Nishikawa, R. M., Sickles, E. A., Karellas, A. & D'Orsi, E. M., Jan 1 2013, In : Radiology. 266, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

SU‐E‐I‐01: Radiation Dose Reduction and Image Quality Evaluation of Coronal Truncated Projections in Cone‐Beam Dedicated Breast CT

Konate, S., Vedantham, S., Shi, L. & Karellas, A., Jun 2013, In : Medical physics. 40, 6, p. 124-125 2 p.

Research output: Contribution to journalArticle

Technical note: Skin thickness measurements using high-resolution flat-panel cone-beam dedicated breast CT

Shi, L., Vedantham, S., Karellas, A. & O'Connell, A. M., Mar 2013, In : Medical physics. 40, 3, 031913.

Research output: Contribution to journalArticle

24 Scopus citations

TU‐F‐137‐01: Writing and Reviewing Papers for Medical Physics

Hendee, W., Slattery, P., Karellas, A. & Rogers, D., Jun 2013, In : Medical physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

WE‐G‐103‐04: X‐Ray Scatter in Differential Phase‐Contrast Breast Imaging Using Gratings‐Based Interferometer

Vedantham, S., Shi, L. & Karellas, A., Jun 2013, In : Medical physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

X-ray phase contrast imaging of the breast: Analysis of tissue simulating materials

Vedantham, S. & Karellas, A., Apr 2013, In : Medical physics. 40, 4, 041906.

Research output: Contribution to journalArticle

14 Scopus citations
2012

Dedicated breast CT: Fibroglandular volume measurements in a diagnostic population

Vedantham, S., Shi, L., Karellas, A. & O'Connell, A. M., Dec 2012, In : Medical physics. 39, 12, p. 7317-7328 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Dedicated breast CT: Radiation dose for circle-plus-line trajectory

Vedantham, S., Shi, L., Karellas, A. & Noo, F., Mar 2012, In : Medical physics. 39, 3, p. 1530-1541 12 p.

Research output: Contribution to journalArticle

18 Scopus citations
57 Scopus citations

Feasibility demonstration of frequency domain terahertz imaging in breast cancer margin determination

Yngvesson, S. K., St. Peter, B., Siqueira, P., Kelly, P., Glick, S., Karellas, A. & Khan, A., Apr 2 2012, Optical Interactions with Tissue and Cells XXIII. 82210N. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8221).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations