• 1351 Citations
  • 16 h-Index
19972020

Research output per year

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Research Output

  • 1351 Citations
  • 16 h-Index
  • 23 Article
  • 2 Short survey

Acidic conditions stabilise intermediates populated during the folding of Im7 and Im9

Gorski, S. A., Capaldi, A. P., Kleanthous, C. & Radford, S. E., Sep 28 2001, In : Journal of Molecular Biology. 312, 4, p. 849-863 15 p.

Research output: Contribution to journalArticle

64 Scopus citations

A DNA polymerase β mutator mutant with reduced nucleotide discrimination and increased protein stability

Shah, A. M., Conn, D. A., Li, S. X., Capaldi, A., Jäger, J. & Sweasy, J. B., Sep 25 2001, In : Biochemistry. 40, 38, p. 11372-11381 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Alterations of signaling pathways in response to chemical perturbations used to measure mRNA decay rates in yeast

Eshleman, N., Luo, X., Capaldi, A. & Buchan, J. R., Jan 1 2020, In : RNA. 26, 1, p. 10-18 9 p.

Research output: Contribution to journalArticle

Open Access

Analysis of gene function using DNA microarrays

Capaldi, A. P., Jan 1 2010, In : Methods in Enzymology. 470, C, p. 3-17 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

An unfolding story

Capaldi, A. P. & Radford, S. E., Dec 1 2001, In : Trends in Biochemical Sciences. 26, 12, 1 p.

Research output: Contribution to journalShort survey

Development of a High-Throughput Fluorescence Polarization Assay to Detect Inhibitors of the FAK–Paxillin Interaction

Marlowe, T., Alvarado, C., Rivera, A., Lenzo, F., Nott, R., Bondugji, D., Montoya, J., Hurley, A., Kaplan, M., Capaldi, A. & Cance, W., Jan 1 2020, In : SLAS Discovery. 25, 1, p. 21-32 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Equilibrium Hydrogen Exchange Reveals Extensive Hydrogen Bonded Secondary Structure in the On-pathway Intermediate of Im7

Gorski, S. A., Le Duff, C. S., Capaldi, A. P., Kalverda, A. P., Beddard, G. S., Moore, G. R. & Radford, S. E., Mar 12 2004, In : Journal of Molecular Biology. 337, 1, p. 183-193 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Genome-wide analysis of the TORC1 and osmotic stress signaling network in Saccharomyces cerevisiae

Worley, J., Sullivan, A., Luo, X., Kaplan, M. E. & Capaldi, A. P., 2016, In : G3: Genes, Genomes, Genetics. 6, 2, p. 463-474 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Im7 folding mechanism: Misfolding on a path to the native state

Capaldi, A. P., Kleanthous, C. & Radford, S. E., Jan 1 2002, In : Nature Structural Biology. 9, 3, p. 209-216 8 p.

Research output: Contribution to journalArticle

245 Scopus citations

Inositol Pyrophosphates Regulate Cell Growth and the Environmental Stress Response by Activating the HDAC Rpd3L

Worley, J., Luo, X. & Capaldi, A. P., May 30 2013, In : Cell Reports. 3, 5, p. 1476-1482 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast

Kunkel, J., Luo, X. & Capaldi, A. P., Dec 1 2019, In : Nature communications. 10, 1, 3558.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Kinetic studies of β-sheet protein folding

Capaldi, A. P. & Radford, S. E., Feb 1998, In : Current Opinion in Structural Biology. 8, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Multilayered regulation of TORC1-body formation in budding yeast

Sullivan, A., Wallace, R. L., Wellington, R., Luo, X. & Capaldi, A. P., Feb 1 2019, In : Molecular biology of the cell. 30, 3, p. 400-410 11 p.

Research output: Contribution to journalArticle

Partially unfolded species populated during equilibrium denaturation of the β-sheet protein Y74W apo-pseudoazurin

Jones, S., Reader, J. S., Healy, M., Capaldi, A. P., Ashcroft, A. E., Kalverda, A. P., Smith, D. A. & Radford, S. E., May 16 2000, In : Biochemistry. 39, 19, p. 5672-5682 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Rapid folding with and without populated intermediates in the homologous four-helix proteins Im7 and Im9

Ferguson, N., Capaldi, A. P., James, R., Kleanthous, C. & Radford, S. E., Mar 12 1999, In : Journal of Molecular Biology. 286, 5, p. 1597-1608 12 p.

Research output: Contribution to journalArticle

224 Scopus citations

Snf1/AMPK promotes the formation of Kog1/raptor-bodies to increase the activation threshold of TORC1 in budding yeast

Hughes Hallett, J. E., Luo, X. & Capaldi, A. P., Oct 6 2015, In : eLife. 4, OCTOBER2015, e09181.

Research output: Contribution to journalArticle

36 Scopus citations

State transitions in the TORC1 signaling pathway and information processing in Saccharomyces cerevisiae

Hughes Hallett, J. E., Luo, X. & Capaldi, A. P., Oct 1 2014, In : Genetics. 198, 2, p. 773-786 14 p.

Research output: Contribution to journalArticle

62 Scopus citations
122 Scopus citations

Structure and function of a transcriptional network activated by the MAPK Hog1

Capaldi, A. P., Kaplan, T., Liu, Y., Habib, N., Regev, A., Friedman, N. & O’shea, E. K., 2008, In : Nature Genetics. 40, 11, p. 1300-1306 7 p.

Research output: Contribution to journalArticle

146 Scopus citations

The Greek key protein apo-pseudoazurin folds through an obligate on-pathway intermediate

Capaldi, A. P., Ferguson, S. J. & Radford, S. E., Mar 12 1999, In : Journal of Molecular Biology. 286, 5, p. 1621-1632 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

The InsP7 phosphatase Siw14 regulates inositol pyrophosphate levels to control localization of the general stress response transcription factor Msn2

Steidle, E. A., Morrissette, V. A., Fujimaki, K., Chong, L., Resnick, A. C., Capaldi, A. P. & Rolfes, R. J., Jan 1 2020, In : Journal of Biological Chemistry. 295, 7, p. 2043-2056 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

TOR-tured Yeast Find a New Way to Stand the Heat

Buchan, J. R., Capaldi, A. P. & Parker, R., Jul 27 2012, In : Molecular cell. 47, 2, p. 155-157 3 p.

Research output: Contribution to journalShort survey

7 Scopus citations

Trapping the on-pathway folding intermediate of Im7 at equilibrium

Spence, G. R., Capaldi, A. P. & Radford, S. E., Jul 30 2004, In : Journal of Molecular Biology. 341, 1, p. 215-226 12 p.

Research output: Contribution to journalArticle

41 Scopus citations

Ultrarapid mixing experiments reveal that Im7 folds via an on-pathway intermediate

Capaldi, A. P., Shastry, M. C. R., Kleanthous, C., Roder, H. & Radford, S. E., Jan 19 2001, In : Nature Structural Biology. 8, 1, p. 68-72 5 p.

Research output: Contribution to journalArticle

150 Scopus citations

Using chimeric immunity proteins to explore the energy landscape for α-helical protein folding

Ferguson, N., Li, W., Capaldi, A. P., Kleanthous, C. & Radford, S. E., Mar 16 2001, In : Journal of Molecular Biology. 307, 1, p. 393-405 13 p.

Research output: Contribution to journalArticle

28 Scopus citations