Ayako Makino

  • 2112 Citations
  • 28 h-Index
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Ayako Makino is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Smooth Muscle Myocytes Medicine & Life Sciences
Pulmonary Hypertension Medicine & Life Sciences
Lung Medicine & Life Sciences
Pulmonary Artery Medicine & Life Sciences
Endothelial Cells Medicine & Life Sciences
Vasoconstriction Medicine & Life Sciences
Blood Vessels Medicine & Life Sciences
Endothelin-1 Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2009 2016

Endoplasmic Reticulum
Endothelial Cells
Blood Vessels
Sarcoplasmic Reticulum Calcium-Transporting ATPases
Endothelial Cells
Blood Vessels
Coronary Disease

Research Output 1997 2019

  • 2112 Citations
  • 28 h-Index
  • 64 Article
  • 4 Chapter
  • 1 Short survey

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog

Schwaerzer, G. K., Kalyanaraman, H., Casteel, D. E., Dalton, N. D., Gu, Y., Lee, S., Zhuang, S., Wahwah, N., Schilling, J. M., Patel, H. H., Zhang, Q., Makino, A., Milewicz, D. M., Peterson, K. L., Boss, G. R. & Pilz, R. B., Dec 1 2019, In : Nature communications. 10, 1, 3533.

Research output: Contribution to journalArticle

Open Access
Cyclic GMP-Dependent Protein Kinases
Oxidative stress
1 Citation (Scopus)

Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension

Wang, Z., Yang, K., Zheng, Q., Zhang, C., Tang, H., Babicheva, A., Jiang, Q., Li, M., Chen, Y., Carr, S. G., Wu, K., Zhang, Q., Balistrieri, A., Wang, C., Song, S., Ayon, R. J., Desai, A., Black, S. M., Garcia, J. G. N., Makino, A. & 3 others, Yuan, J. X. J., Lu, W. & Wang, J., Jan 1 2019, In : American journal of physiology. Lung cellular and molecular physiology. 316, 1, p. L216-L228

Research output: Contribution to journalArticle

Pulmonary Hypertension
Smooth Muscle Myocytes
Hypoxia-Inducible Factor 1
Endothelial Cells
4 Citations (Scopus)

Akt2 (protein kinase B beta) stabilizes ATP7A, a copper transporter for extracellular superoxide dismutase, in vascular smooth muscle: Novel mechanism to limit endothelial dysfunction in type 2 diabetes mellitus

Sudhahar, V., Okur, M. N., Bagi, Z., O'Bryan, J. P., Hay, N., Makino, A., Patel, V. S., Phillips, S. A., Stepp, D., Ushio-Fukai, M. & Fukai, T., Jan 1 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 529-541 13 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
Vascular Smooth Muscle
Type 2 Diabetes Mellitus
Superoxide Dismutase
2 Citations (Scopus)

Diabetes Mellitus Associates with Increased Right Ventricular Afterload and Remodeling in Pulmonary Arterial Hypertension

Whitaker, M. E., Nair, V., Sinari, S., Dherange, P. A., Natarajan, B., Trutter, L., Brittain, E. L., Hemnes, A. R., Austin, E. D., Patel, K., Black, S. M., Garcia, J. GN., Yuan, MD PhD, J. X., Vanderpool, R. R., Rischard, F., Makino, A., Bedrick, E. J. & Desai, A., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

Ventricular Remodeling
Pulmonary Hypertension
Diabetes Mellitus
Right Ventricular Dysfunction
Glycosylated Hemoglobin A
26 Citations (Scopus)

Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition

Tang, H., Babicheva, A., McDermott, K., Gu, Y., Ayon, R. J., Song, S., Wang, Z., Gupta, A., Zhou, T., Sun, X., Dash, S., Wang, Z., Balistrieri, A., Zheng, Q., Cordery, A. G., Desai, A., Rischard, F., Khalpey, Z. I., Wang, J., Black, S. M. & 3 others, Garcia, J. GN., Makino, A. & Yuan, J., Feb 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 2, p. L256-L275

Research output: Contribution to journalArticle

Pulmonary Hypertension
Endothelial Cells
Prolyl Hydroxylases
Smooth Muscle Myocytes