Ayako Makino

Schwaerzer, G. K., Kalyanaraman, H., Casteel, D. E., Dalton, N. D., Gu, Y., Lee, S., Zhuang, S., Wahwah, N., Schilling, J. M., Patel, H. H., Zhang, Q., Makino, A., Milewicz, D. M., Peterson, K. L., Boss, G. R. & Pilz, R. B., Dec 1 2019, In : Nature communications. 10, 1, 3533.

Research output: Contribution to journal › Article

Open Access

Cyclic GMP-Dependent Protein Kinases

vitamins

Oxidative stress

antioxidants

pathology

1 Citation (Scopus)

Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension

Wang, Z., Yang, K., Zheng, Q., Zhang, C., Tang, H., Babicheva, A., Jiang, Q., Li, M., Chen, Y., Carr, S. G., Wu, K., Zhang, Q., Balistrieri, A., Wang, C., Song, S., Ayon, R. J., Desai, A., Black, S. M., Garcia, J. GN., Makino, A. & 3 others, Yuan, J., Lu, W. & Wang, J., Jan 1 2019, In : American journal of physiology. Lung cellular and molecular physiology. 316, 1, p. L216-L228

Research output: Contribution to journal › Article

Pulmonary Hypertension

Smooth Muscle Myocytes

Lung

Hypoxia-Inducible Factor 1

Endothelial Cells

3 Citations (Scopus)

Akt2 (protein kinase B beta) stabilizes ATP7A, a copper transporter for extracellular superoxide dismutase, in vascular smooth muscle: Novel mechanism to limit endothelial dysfunction in type 2 diabetes mellitus

Sudhahar, V., Okur, M. N., Bagi, Z., O'Bryan, J. P., Hay, N., Makino, A., Patel, V. S., Phillips, S. A., Stepp, D., Ushio-Fukai, M. & Fukai, T., Jan 1 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 529-541 13 p.

Research output: Contribution to journal › Article

Proto-Oncogene Proteins c-akt

Vascular Smooth Muscle

Type 2 Diabetes Mellitus

Superoxide Dismutase

Copper

2 Citations (Scopus)

Diabetes Mellitus Associates with Increased Right Ventricular Afterload and Remodeling in Pulmonary Arterial Hypertension

Whitaker, M. E., Nair, V., Sinari, S., Dherange, P. A., Natarajan, B., Trutter, L., Brittain, E. L., Hemnes, A. R., Austin, E. D., Patel, K., Black, S. M., Garcia, J. GN., Yuan, MD PhD, J. X., Vanderpool, R. R., Rischard, F., Makino, A., Bedrick, E. J. & Desai, A., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journal › Article

Ventricular Remodeling

Pulmonary Hypertension

Diabetes Mellitus

Right Ventricular Dysfunction

Glycosylated Hemoglobin A

21 Citations (Scopus)

Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition

Tang, H., Babicheva, A., McDermott, K., Gu, Y., Ayon, R. J., Song, S., Wang, Z., Gupta, A., Zhou, T., Sun, X., Dash, S., Wang, Z., Balistrieri, A., Zheng, Q., Cordery, A. G., Desai, A., Rischard, F., Khalpey, Z. I., Wang, J., Black, S. M. & 3 others, Garcia, J. GN., Makino, A. & Yuan, J., Feb 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 2, p. L256-L275

Research output: Contribution to journal › Article

Pulmonary Hypertension

Endothelial Cells

Lung

Prolyl Hydroxylases

Smooth Muscle Myocytes