Ayako Makino

  • 1971 Citations
  • 26 h-Index
19972019
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  • 15 Similar Profiles
Smooth Muscle Myocytes Medicine & Life Sciences
Pulmonary Hypertension Medicine & Life Sciences
Lung Medicine & Life Sciences
Pulmonary Artery Medicine & Life Sciences
Endothelial Cells Medicine & Life Sciences
Vasoconstriction Medicine & Life Sciences
Blood Vessels Medicine & Life Sciences
Endothelin-1 Medicine & Life Sciences

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Projects 2009 2016

Endoplasmic Reticulum
Endothelial Cells
Blood Vessels
Sarcoplasmic Reticulum Calcium-Transporting ATPases
Mitochondria
Endothelial Cells
Blood Vessels
Hyperglycemia
Coronary Disease
Down-Regulation

Research Output 1997 2019

  • 1971 Citations
  • 26 h-Index
  • 63 Article
  • 3 Chapter
  • 1 Short survey

Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension

Wang, Z., Yang, K., Zheng, Q., Zhang, C., Tang, H., Babicheva, A., Jiang, Q., Li, M., Chen, Y., Carr, S. G., Wu, K., Zhang, Q., Balistrieri, A., Wang, C., Song, S., Ayon, R. J., Desai, A., Black, S. M., Garcia, J. G. N., Makino, A. & 3 othersYuan, J., Lu, W. & Wang, J., Jan 1 2019, In : American journal of physiology. Lung cellular and molecular physiology. 316, 1, p. L216-L228

Research output: Contribution to journalArticle

Pulmonary Hypertension
Smooth Muscle Myocytes
Lung
Hypoxia-Inducible Factor 1
Endothelial Cells
2 Citations (Scopus)

Akt2 (protein kinase B beta) stabilizes ATP7A, a copper transporter for extracellular superoxide dismutase, in vascular smooth muscle: Novel mechanism to limit endothelial dysfunction in type 2 diabetes mellitus

Sudhahar, V., Okur, M. N., Bagi, Z., O'Bryan, J. P., Hay, N., Makino, A., Patel, V. S., Phillips, S. A., Stepp, D., Ushio-Fukai, M. & Fukai, T., Jan 1 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 529-541 13 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
Vascular Smooth Muscle
Type 2 Diabetes Mellitus
Superoxide Dismutase
Copper
2 Citations (Scopus)

Diabetes Mellitus Associates with Increased Right Ventricular Afterload and Remodeling in Pulmonary Arterial Hypertension

Whitaker, M. E., Nair, V., Sinari, S., Dherange, P. A., Natarajan, B., Trutter, L., Brittain, E. L., Hemnes, A. R., Austin, E. D., Patel, K., Black, S. M., Garcia, J. GN., Yuan, MD PhD, J. X., Vanderpool, R. R., Rischard, F., Makino, A., Bedrick, E. J. & Desai, A., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

Ventricular Remodeling
Pulmonary Hypertension
Diabetes Mellitus
Right Ventricular Dysfunction
Glycosylated Hemoglobin A
14 Citations (Scopus)

Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition

Tang, H., Babicheva, A., McDermott, K., Gu, Y., Ayon, R. J., Song, S., Wang, Z., Gupta, A., Zhou, T., Sun, X., Dash, S., Wang, Z., Balistrieri, A., Zheng, Q., Cordery, A. G., Desai, A., Rischard, F., Khalpey, Z. I., Wang, J., Black, S. M. & 3 othersGarcia, J. GN., Makino, A. & Yuan, J., Feb 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 2, p. L256-L275

Research output: Contribution to journalArticle

Pulmonary Hypertension
Endothelial Cells
Lung
Prolyl Hydroxylases
Smooth Muscle Myocytes
5 Citations (Scopus)

Hypoxia selectively upregulates cation channels and increases cytosolic [Ca2+] in pulmonary, but not coronary, arterial smooth muscle cells

He, X., Song, S., Ayon, R. J., Balisterieri, A., Black, S. M., Makino, A., Wier, W. G., Zang, W. J. & Yuan, J., Apr 1 2018, In : American Journal of Physiology - Cell Physiology. 314, 4, p. C504-C517

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Cations
Up-Regulation
Lung
Vasoconstriction