• 5643 Citations
  • 43 h-Index
1978 …2020

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Article
138 Scopus citations

5-Azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs

Efferth, T., Futscher, B. W. & Osieka, R., Jan 1 2001, In : Blood Cells, Molecules, and Diseases. 27, 3, p. 637-648 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells

Rice, J. C., Massey-Brown, K. S. & Futscher, B. W., Oct 8 1998, In : Oncogene. 17, 14, p. 1807-1812 6 p.

Research output: Contribution to journalArticle

Open Access
193 Scopus citations

Aberrant methylation of the maspin promoter is an early event in human breast cancer

Futscher, B. W., O'Meara, M. M., Kim, C. J., Rennels, M. A., Lu, D., Gruman, L. M., Seftor, R. E. B., Hendrix, M. J. C. & Domann, F. E., Jul 1 2004, In : Neoplasia. 6, 4, p. 380-389 10 p.

Research output: Contribution to journalArticle

56 Scopus citations

Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells

Lee, J. K., Garbe, J. C., Vrba, L., Miyano, M., Futscher, B. W., Stampfer, M. R. & LaBarge, M. A., Mar 11 2015, In : Frontiers in Cell and Developmental Biology. 3, MAR, 13.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation

Severson, P. L., Tokar, E. J., Vrba, L., Waalkes, M. P. & Futscher, B. W., Nov 2012, In : Epigenetics. 7, 11, p. 1238-1248 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Agglomerative epigenetic aberrations are a common event in human breast cancer

Novak, P., Jensen, T., Oshiro, M. M., Watts, G. S., Kim, C. J. & Futscher, B. W., Oct 15 2008, In : Cancer Research. 68, 20, p. 8616-8625 10 p.

Research output: Contribution to journalArticle

99 Scopus citations

A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers

Vrba, L., Garbe, J. C., Stampfer, M. R. & Futscher, B. W., Jan 1 2015, In : Epigenetics. 10, 11, p. 1074-1083 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Analysis of MRP mRNA in mitoxantrone-selected, multidrug-resistant human tumor cells

Futscher, B. W., Abbaszadegan, M. R., Domann, F. & Dalton, W. S., Apr 29 1994, In : Biochemical Pharmacology. 47, 9, p. 1601-1606 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Analysis of Multidrug Resistance-associated Protein (MRP) Messenger RNA in Normal and Malignant Hematopoietic Cells

Abbaszadegan, M. R., Futscher, B. W., Klimecki, W. T., List, A. & Dalton, W. S., Sep 1994, In : Cancer Research. 54, 17, p. 4676-4679 4 p.

Research output: Contribution to journalArticle

103 Scopus citations

Analysis of the Harvey ras gene in cisplatin-initiated mouse skin tumors by polymerase chain reaction and direct DNA sequencing

Nelson, M. A., Futscher, B. W., Loew, M. R. & Tim Bowden, G., Jul 31 1992, In : Cancer Letters. 65, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

AP-2α and AP-2γ are transcriptional targets of p53 in human breast carcinoma cells

Li, H., Watts, G. S., Oshiro, M. M., Futscher, B. W. & Domann, F. E., Aug 31 2006, In : Oncogene. 25, 39, p. 5405-5415 11 p.

Research output: Contribution to journalArticle

22 Scopus citations
38 Scopus citations

Arsenic exposure induces the warburg effect in cultured human cells

Zhao, F., Severson, P., Pacheco, S., Futscher, B. W. & Klimecki, W. T., Aug 5 2013, In : Toxicology and Applied Pharmacology. 271, 1, p. 72-77 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

A suite of DNA methylation markers that can detect most common human cancers

Vrba, L. & Futscher, B. W., Feb 1 2018, (Accepted/In press) In : Epigenetics. p. 1-12 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

cDNA microarray analysis of multidrug resistance: Doxorubicin selection produces multiple defects in apoptosis signaling pathways

Watts, G. S., Futscher, B. W., Isett, R., Gleason-Guzman, M., Kunkel, M. W. & Salmon, S. E., Oct 30 2001, In : Journal of Pharmacology and Experimental Therapeutics. 299, 2, p. 434-441 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Cell-Type Specific DNA Methylation Patterns Define Human Breast Cellular Identity

Novak, P., Stampfer, M. R., Munoz-Rodriguez, J. L., Garbe, J. C., Ehrich, M., Futscher, B. W. & Jensen, T. J., Dec 20 2012, In : PloS one. 7, 12, e52299.

Research output: Contribution to journalArticle

16 Scopus citations

Changes in c-myc and c-fos Expression in a Human Tumor Cell Line following Exposure to Bifunctional Alkylating Agents

Erickson, L. C. & Futscher, B. W., Jan 1 1990, In : Cancer Research. 50, 1, p. 62-66 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Characterization of a novel radiation-induced sarcoma cell line

Lang, J., Zhu, W., Nokes, B., Sheth, G., Novak, P., Fuchs, L., Watts, G., Futscher, B., Mineyev, N., Ring, A., Lebeau, L., Nagle, R. & Cranmer, L., May 1 2015, In : Journal of Surgical Oncology. 111, 6, p. 669-682 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Characterization of hepatocellular carcinoma related genes and metabolites in human nonalcoholic fatty liver disease

Clarke, J. D., Novak, P., Lake, A. D., Shipkova, P., Aranibar, N., Robertson, D., Severson, P. L., Reily, M. D., Futscher, B. W., Lehman-Mckeeman, L. D. & Cherrington, N. J., Feb 1 2014, In : Digestive diseases and sciences. 59, 2, p. 365-374 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Collateral Sensitivity to Nitrosoureas in Multidrug-resistant Cells Selected with Verapamil

Futscher, B. W., Campbell, K. & Dalton, W. S., Sep 1992, In : Cancer Research. 52, 18, p. 5013-5017 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Comparisons of PCR-based genome amplification systems using CpG island microarrays

Pike, B. L., Groshen, S., Hsu, Y. H., Shai, R. M., Wang, X., Holtan, N., Futscher, B. W. & Hacia, J. G., Jun 1 2006, In : Human Mutation. 27, 6, p. 589-596 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation

Severson, P. L., Tokar, E. J., Vrba, L., Waalkes, M. P. & Futscher, B. W., Oct 2013, In : Epigenetics. 8, 10, p. 1080-1088 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Decreased CP-1 (NF-Y) activity results in transcriptional down-regulation of topoisomerase IIα in a doxorubicin-resistant variant of human multiple myeloma RPMI 8226

Wang, H., Jiang, Z. G., Wong, Y. W., Dalton, W. S., Futscher, B. W. & Chan, V. T. W., Aug 18 1997, In : Biochemical and Biophysical Research Communications. 237, 2, p. 217-224 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
Open Access
112 Scopus citations

Developmental expression of N-acetyltransferases in C57BI/6 mice

Mitchell, M. K., Futscher, B. W. & McQueen, C. A., Feb 16 1999, In : Drug Metabolism and Disposition. 27, 2, p. 261-264 4 p.

Research output: Contribution to journalArticle

34 Scopus citations

Differentially expressed MicroRNAs in postpartum breast cancer in Hispanic women

Muñoz-Rodríguez, J. L., Vrba, L., Futscher, B. W., Hu, C., Komenaka, I. K., Meza-Montenegro, M. M., Gutierrez-Millan, L. E., Daneri-Navarro, A., Thompson, P. A. & Martinez, M. E., Apr 13 2015, In : PloS one. 10, 4, e0124340.

Research output: Contribution to journalArticle

18 Scopus citations

Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells

Junk, D. J., Vrba, L., Watts, G. S., Oshiro, M. M., Martinez, J. D. & Futscher, B. W., May 2008, In : Neoplasia. 10, 5, p. 450-461 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

Direct correlation between methylation status and expression of the human O-6-methylguanine DNA methyltransferase gene

Pieper, R. O., Costello, J. F., Kroes, R. A., Futscher, B. W., Marathi, U. & Erickson, L. C., Jan 1 1991, In : Cancer communications. 3, 8, p. 241-253 13 p.

Research output: Contribution to journalArticle

58 Scopus citations

DNA–Damaging and Transcription‐Terminating Lesions Induced by AF64A In Vitro

Futscher, B. W., Pieper, R. O., Barnes, D. M., Hanin, I. & Erickson, L. C., Apr 1992, In : Journal of neurochemistry. 58, 4, p. 1504-1509 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients

Vrba, L., Oshiro, M. M., Kim, S. S., Garland, L. L., Placencia, C., Mahadevan, D., Nelson, M. A. & Futscher, B. W., Apr 2 2020, In : Epigenetics. 15, 4, p. 419-430 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
Open Access

Effects of ethanol and paraformaldehyde on RNA yield and quality

Klimecki, W. T., Futscher, B. W. & Dalton, W. S., Jan 1 1994, In : BioTechniques. 16, 6, p. 1021-1023 3 p.

Research output: Contribution to journalArticle

25 Scopus citations

Epigenetic inactivation of the HOXA gene cluster in breast cancer

Novak, P., Jensen, T., Oshiro, M. M., Wozniak, R. J., Nouzova, M., Watts, G. S., Klimecki, W. T., Kim, C. & Futscher, B. W., Nov 15 2006, In : Cancer Research. 66, 22, p. 10664-10670 7 p.

Research output: Contribution to journalArticle

90 Scopus citations

Epigenetic mediated transcriptional activation of WNT5A participates in arsenical-associated malignant transformation

Jensen, T. J., Wozniak, R. J., Eblin, K. E., Wnek, S. M., Gandolfi, A. J. & Futscher, B. W., Feb 15 2009, In : Toxicology and Applied Pharmacology. 235, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

Epigenetic regulation of maspin expression in human ovarian carcinoma cells

Rose, S. L., Fitzgerald, M. P., White, N. O., Hitchler, M. J., Futscher, B. W., De Geest, K. & Domann, F. E., Aug 1 2006, In : Gynecologic oncology. 102, 2, p. 319-324 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Epigenetic regulation of normal human mammary cell type-specific miRNAs

Vrba, L., Garbe, J. C., Stampfer, M. R. & Futscher, B. W., Dec 2011, In : Genome Research. 21, 12, p. 2026-2037 12 p.

Research output: Contribution to journalArticle

65 Scopus citations

Epigenetic regulation of the cell type-specific gene 14-3-3σ

Oshiro, M. M., Futscher, B. W., Lisberg, A., Wozniak, R. J., Klimecki, W. T., Domann, F. E. & Cress, A. E., Sep 2005, In : Neoplasia. 7, 9, p. 799-808 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Epigenetic remodeling during arsenical-induced malignant transformation

Jensen, T. J., Novak, P., Eblin, K. E., Gandolfi, J. A. & Futscher, B. W., Aug 22 2008, In : Carcinogenesis. 29, 8, p. 1500-1508 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

Epigenetic silencing of DSC3 is a common event in human breast cancer

Oshiro, M. M., Kim, C. J., Wozniak, R. J., Junk, D. J., Muñoz-Rodríguez, J. L., Burr, J. A., Fitzgerald, M., Pawar, S. C., Cress, A. E., Domann, F. E. & Futscher, B. W., Jun 16 2005, In : Breast Cancer Research. 7, 5, R669.

Research output: Contribution to journalArticle

Open Access
82 Scopus citations

Epigenetic silencing of lncRNA MORT in 16 TCGA cancer types

Vrba, L. & Futscher, B. W., 2018, In : F1000Research. 7, 211.

Research output: Contribution to journalArticle

17 Scopus citations

Epigenetic silencing of maspin gene expression in human breast cancers

Domann, F. E., Rice, J. C., Hendrix, M. J. C. & Futscher, B. W., Mar 15 2000, In : International Journal of Cancer. 85, 6, p. 805-810 6 p.

Research output: Contribution to journalArticle

169 Scopus citations
7 Scopus citations

Epigenomic changes during leukemia cell differentiation: Analysis of histone acetylation and cytosine methylation using CpG island microarrays

Nouzova, M., Holtan, N., Oshiro, M. M., Isett, R. B., Munoz-Rodriguez, J. L., List, A. F., Narro, M. L., Miller, S. J., Merchant, N. C. & Futscher, B. W., Dec 2004, In : Journal of Pharmacology and Experimental Therapeutics. 311, 3, p. 968-981 14 p.

Research output: Contribution to journalArticle

68 Scopus citations

Evidence for cytoplasmic P-glycoprotein location associated with increased multidrug resistance and resistance to chemosensitizers

Abbaszadegan, M. R., Cress, A. E., Futscher, B. W., Bellamy, W. T. & Dalton, W. S., Dec 1 1996, In : Cancer Research. 56, 23, p. 5435-5442 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells

Severson, P. L., Vrba, L., Stampfer, M. R. & Futscher, B. W., Dec 1 2014, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 775-776, p. 48-54 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Expression of ribosomal phosphoprotein po is induced by antitumor agents and increased in mer human tumor cell lines

Grabowski, D. T., Pieper, R. O., Futscher, B. W., Deutsch, W. A., Erickson, L. C. & Kelley, M. R., Feb 1 1992, In : Carcinogenesis. 13, 2, p. 259-263 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Gene amplification affecting o-alkylguanine-dna alkyltransferase activity is not detected in nitrosourea resistant or sensitive human cell lines

Vlahos, N. S., Futscher, B. W., Hora, N. K., Trent, J. M. & Erickson, L. C., Mar 1 1990, In : Carcinogenesis. 11, 3, p. 479-483 5 p.

Research output: Contribution to journalArticle

3 Scopus citations