Projects per year
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Cyclization
Chemical Compounds
Scaffolds
Chemical Compounds
Cyanides
Medicine & Life Sciences
Microwaves
Medicine & Life Sciences
Azides
Medicine & Life Sciences
Libraries
Medicine & Life Sciences
Lactams
Chemical Compounds
Condensation
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2009 2014
- 2 Finished
Expeditious, biologically driven Pilot Libraries for File Enhancement
8/5/10 → 5/31/14
Project: Research project › Biotechnology Resource Grants
Libraries
Pharmaceutical Chemistry
Drug Design
Research Personnel
Databases
The Southwest Comprehensive Center for Drug Discovery and Development
Hulme, C., Mousses, S., Berens, M. E. & Meurice, N.
9/30/09 → 12/31/11
Project: Research project › High Impact Research and Research Infrastructure Programs
Drug Discovery
Pharmaceutical Chemistry
Molecular Probes
Libraries
Industry
Research Output 1993 2018
Aza-Riley Oxidation of Ugi-Azide and Ugi-3CR Products toward Vicinal Tricarbonyl Amides: Two-Step MCR-Oxidation Methodology Accessing Functionalized α,β-Diketoamides and α,β-Diketotetrazoles
Foley, C., Shaw, A. & Hulme, C. Mar 2 2018 In : Organic Letters. 20, 5, p. 1275-1278 4 p.Research output: Contribution to journal › Article
Transformer substations
Affinity chromatography
Deamination
Azides
Amides
Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance
Zhang, J., Hu, Y., Foley, C., Wang, Y., Musharrafieh, R., Xu, S., Zhang, Y., Ma, C., Hulme, C. & Wang, J. Dec 1 2018 In : Scientific Reports. 8, 1, 4653Research output: Contribution to journal › Article
Azides
Drug Resistance
Human Influenza
Antiviral Agents
Oseltamivir
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes
Muñoz-Torrero, D., Mangoni, A. A., Guillou, C., Collina, S., Eynde, J. J. V., Rautio, J., Keseru, G. M., Hulme, C., Chibale, K., Luque, F. J., Karaman, R., Gütschow, M., Liu, H. & Ragno, R. May 1 2017 In : Molecules. 22, 5, 743Research output: Contribution to journal › Review article
Slip forming
2
Citations
Copper(i) catalyzed oxidative hydrolysis of Ugi 3-component and Ugi-azide reaction products towards 2° α-ketoamides and α-ketotetrazoles
Collet, J. W., Foley, C., Shaw, A. Y., Orru, R. V. A., Ruijter, E. & Hulme, C. 2017 In : Organic and Biomolecular Chemistry. 15, 29, p. 6132-6135 4 p.Research output: Contribution to journal › Article
Tetrazoles
Azides
Cyanides
Reaction products
Aldehydes
1
Citations
Dyrk1 inhibition improves Alzheimer's disease-like pathology
Branca, C., Shaw, D. M., Belfiore, R., Gokhale, V., Shaw, A. Y., Foley, C., Smith, B., Hulme, C., Dunckley, T., Meechoovet, B., Caccamo, A. & Oddo, S. Oct 1 2017 In : Aging Cell. 16, 5, p. 1146-1154 9 p.Research output: Contribution to journal › Article
Alzheimer Disease
Pathology
Amyloid beta-Protein Precursor
Amyloid
Phosphorylation