Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Cyclization Chemical Compounds
Scaffolds Chemical Compounds
Cyanides Medicine & Life Sciences
Microwaves Medicine & Life Sciences
Azides Medicine & Life Sciences
Libraries Medicine & Life Sciences
Lactams Chemical Compounds
Condensation Chemical Compounds

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Projects 2009 2014

Expeditious, biologically driven Pilot Libraries for File Enhancement

Hulme, C.

National Institutes of Health

8/5/105/31/14

Project: Research projectBiotechnology Resource Grants

Libraries
Pharmaceutical Chemistry
Drug Design
Research Personnel
Databases

The Southwest Comprehensive Center for Drug Discovery and Development

Hulme, C., Mousses, S., Berens, M. E. & Meurice, N.

National Institutes of Health

9/30/0912/31/11

Project: Research projectHigh Impact Research and Research Infrastructure Programs

Drug Discovery
Pharmaceutical Chemistry
Molecular Probes
Libraries
Industry

Research Output 1993 2018

  • 5297 Citations
  • 35 h-Index
  • 112 Article
  • 3 Chapter
  • 2 Review article
Transformer substations
Affinity chromatography
Deamination
Azides
Amides

Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance

Zhang, J., Hu, Y., Foley, C., Wang, Y., Musharrafieh, R., Xu, S., Zhang, Y., Ma, C., Hulme, C. & Wang, J. Dec 1 2018 In : Scientific Reports. 8, 1, 4653

Research output: Contribution to journalArticle

Azides
Drug Resistance
Human Influenza
Antiviral Agents
Oseltamivir

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes

Muñoz-Torrero, D., Mangoni, A. A., Guillou, C., Collina, S., Eynde, J. J. V., Rautio, J., Keseru, G. M., Hulme, C., Chibale, K., Luque, F. J., Karaman, R., Gütschow, M., Liu, H. & Ragno, R. May 1 2017 In : Molecules. 22, 5, 743

Research output: Contribution to journalReview article

Slip forming
2 Citations

Copper(i) catalyzed oxidative hydrolysis of Ugi 3-component and Ugi-azide reaction products towards 2° α-ketoamides and α-ketotetrazoles

Collet, J. W., Foley, C., Shaw, A. Y., Orru, R. V. A., Ruijter, E. & Hulme, C. 2017 In : Organic and Biomolecular Chemistry. 15, 29, p. 6132-6135 4 p.

Research output: Contribution to journalArticle

Tetrazoles
Azides
Cyanides
Reaction products
Aldehydes
1 Citations

Dyrk1 inhibition improves Alzheimer's disease-like pathology

Branca, C., Shaw, D. M., Belfiore, R., Gokhale, V., Shaw, A. Y., Foley, C., Smith, B., Hulme, C., Dunckley, T., Meechoovet, B., Caccamo, A. & Oddo, S. Oct 1 2017 In : Aging Cell. 16, 5, p. 1146-1154 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Pathology
Amyloid beta-Protein Precursor
Amyloid
Phosphorylation