• 1736 Citations
  • 19 h-Index
19982020
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  • 10 Similar Profiles
Drosophila Medicine & Life Sciences
Amyotrophic Lateral Sclerosis Medicine & Life Sciences
RNA-Binding Proteins Medicine & Life Sciences
Fragile X Syndrome Medicine & Life Sciences
Fragile X Mental Retardation Protein Medicine & Life Sciences
Proteins Medicine & Life Sciences
RNA Medicine & Life Sciences
Spectrin Medicine & Life Sciences

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Projects 2003 2020

RNA dysregulation in neurodegeneration

Zarnescu, D. C.

National Institutes of Health

9/1/155/31/20

Project: Research projectResearch Project

Amyotrophic Lateral Sclerosis
RNA
Protein Biosynthesis
Motor Neurons
Neurodegenerative Diseases

Deciphering RNA based mechanisms of neurodegeneration

Zarnescu, D. C.

National Institutes of Health

9/1/128/31/15

Project: Research projectExploratory/Developmental Grants

RNA
RNA-Binding Proteins
Drosophila
Motor Neurons
Fragile X Syndrome

Characterization of a novel Fragile X interacting gene

Zarnescu, D. C.

National Institutes of Health

8/1/037/31/06

Project: Research projectPostdoctoral Individual National Research Service Award

Myosin Type V
Fragile X Syndrome
Intellectual Disability
Drosophila
Genes

Research Output 1998 2018

  • 1736 Citations
  • 19 h-Index
  • 36 Article
  • 2 Chapter
  • 1 Conference contribution
  • 1 Review article
1 Citations

Dynamic duo – FMRP and TDP-43: Regulating common targets, causing different diseases

Ferro, D., Yao, S. & Zarnescu, D. C., Jan 1 2018, (Accepted/In press) In : Brain Research.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
RNA-Binding Proteins
RNA Sequence Analysis
Neuronal Plasticity
DNA-Binding Proteins
1 Citations

Increased Cardiac Arrhythmogenesis Associated with Gap Junction Remodeling with Upregulation of RNA-Binding Protein FXR1

Chu, M., Novak, S. M., Cover, C., Wang, A. A., Chinyere, I. R., Juneman, E. B., Zarnescu, D. C., Wong, P. K. & Gregorio, C. C., Feb 6 2018, In : Circulation. 137, 6, p. 605-618 14 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Gap Junctions
Up-Regulation
Dilated Cardiomyopathy
Heart Diseases

Lost in translation: Evidence for protein synthesis deficits in ALS/FTD and related neurodegenerative diseases

Lehmkuhl, E. M. & Zarnescu, D. C., Jan 1 2018, Advances in Neurobiology. Springer New York LLC, p. 283-301 19 p. (Advances in Neurobiology; vol. 20)

Research output: Chapter in Book/Report/Conference proceedingChapter

Protein Biosynthesis
Neurodegenerative Diseases
Thorium alloys
Roadbuilding materials
Thermionic emission

Medium-chain fatty acids, beta-hydroxybutyric acid and genetic modulation of the carnitine shuttle are protective in a drosophila model of ALS based on TDP-43

Manzo, E., O’Conner, A. G., Barrows, J. M., Shreiner, D. D., Birchak, G. J. & Zarnescu, D. C., May 31 2018, In : Frontiers in Molecular Neuroscience. 11, 182

Research output: Contribution to journalArticle

3-Hydroxybutyric Acid
Carnitine
Drosophila
Fatty Acids
Lipid Metabolism

MiR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila

Daniel, S. G., Russ, A. D., Guthridge, K. M., Raina, A. I., Estes, P. S., Parsons, L. M., Richardson, H. E., Schroeder, J. A. & Zarnescu, D. C., Jan 1 2018, In : Biology Open. 7, 1, bio027391

Research output: Contribution to journalArticle

Growth Inhibitors
MicroRNAs
Drosophila
Larva
microRNA