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  • 9 Similar Profiles
Drosophila Medicine & Life Sciences
Amyotrophic Lateral Sclerosis Medicine & Life Sciences
RNA-Binding Proteins Medicine & Life Sciences
Fragile X Syndrome Medicine & Life Sciences
Fragile X Mental Retardation Protein Medicine & Life Sciences
Proteins Medicine & Life Sciences
RNA Medicine & Life Sciences
Spectrin Medicine & Life Sciences

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Projects 2003 2020

RNA dysregulation in neurodegeneration

Zarnescu, D. C.

National Institutes of Health

9/1/155/31/20

Project: Research projectResearch Project

Amyotrophic Lateral Sclerosis
RNA
Protein Biosynthesis
Motor Neurons
Neurodegenerative Diseases

Deciphering RNA based mechanisms of neurodegeneration

Zarnescu, D. C.

National Institutes of Health

9/1/128/31/15

Project: Research projectExploratory/Developmental Grants

RNA
RNA-Binding Proteins
Drosophila
Motor Neurons
Fragile X Syndrome

Characterization of a novel Fragile X interacting gene

Zarnescu, D. C.

National Institutes of Health

8/1/037/31/06

Project: Research projectPostdoctoral Individual National Research Service Award

Myosin Type V
Fragile X Syndrome
Intellectual Disability
Drosophila
Genes

Research Output 1998 2018

  • 1684 Citations
  • 19 h-Index
  • 34 Article
  • 1 Chapter
  • 1 Conference contribution
  • 1 Review article

Dynamic duo – FMRP and TDP-43: Regulating common targets, causing different diseases

Ferro, D., Yao, S. & Zarnescu, D. C. Jan 1 2018 (Accepted/In press) In : Brain Research.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
RNA-Binding Proteins
RNA Sequence Analysis
Neuronal Plasticity
DNA-Binding Proteins

MiR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila

Daniel, S. G., Russ, A. D., Guthridge, K. M., Raina, A. I., Estes, P. S., Parsons, L. M., Richardson, H. E., Schroeder, J. A. & Zarnescu, D. C. Jan 1 2018 In : Biology Open. 7, 1, bio027391

Research output: Contribution to journalArticle

Growth Inhibitors
MicroRNAs
Drosophila
Larva
microRNA
8 Citations

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

Chou, C. C. , Zhang, Y. , Umoh, M. E. , Vaughan, S. W. , Lorenzini, I. , Liu, F. , Sayegh, M. , Donlin-Asp, P. G. , Chen, Y. H. , Duong, D. M. , Seyfried, N. T. , Powers, M. A. , Kukar, T. , Hales, C. M. , Gearing, M. , Cairns, N. J. , Boylan, K. B. , Dickson, D. W. , Rademakers, R. , Zhang, Y. J. & 5 others Petrucelli, L., Sattler, R., Zarnescu, D. C., Glass, J. D. & Rossoll, W. Feb 1 2018 In : Nature Neuroscience. 21, 2, p. 228-239 12 p.

Research output: Contribution to journalArticle

Nuclear Pore
Cell Nucleus Active Transport
DNA-Binding Proteins
Pathology
Nuclear Pore Complex Proteins
2 Citations

Endocytosis regulates TDP-43 toxicity and turnover

Liu, G., Coyne, A. N., Pei, F., Vaughan, S., Chaung, M., Zarnescu, D. C. & Buchan, J. R. Dec 1 2017 In : Nature Communications. 8, 1, 2092

Research output: Contribution to journalArticle

cells and cell components
nervous system disorder
physiology
Amyotrophic Lateral Sclerosis
pathology
3 Citations

Failure to deliver and translate—new insights into RNA dysregulation in ALS

Coyne, A. N., Zaepfel, B. L. & Zarnescu, D. C. Aug 17 2017 In : Frontiers in Cellular Neuroscience. 11, 243

Research output: Contribution to journalReview article

Amyotrophic Lateral Sclerosis
RNA
RNA-Binding Proteins
Mutation
RNA Transport