Dominik Schenten

  • 1952 Citations
  • 21 h-Index
19982018

Research output per year

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Research Output

  • 1952 Citations
  • 21 h-Index
  • 24 Article
  • 1 Book
2018

Programming of CD8 T Cell Quantity and Polyfunctionality by Direct IL-1 Signals

Sarkar, S., Yuzefpolskiy, Y., Xiao, H., Baumann, F. M., Yim, S., Lee, D. J., Schenten, D. & Kalia, V., Dec 15 2018, In : Journal of Immunology. 201, 12, p. 3641-3650 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2014

A20-Deficient Mast Cells Exacerbate Inflammatory Responses In Vivo

Heger, K., Fierens, K., Vahl, J. C., Aszodi, A., Peschke, K., Schenten, D., Hammad, H., Beyaert, R., Saur, D., van Loo, G., Roers, A., Lambrecht, B. N., Kool, M. & Schmidt-Supprian, M., Jan 2014, In : PLoS Biology. 12, 1, e1001762.

Research output: Contribution to journalArticle

39 Scopus citations

Author response

Nish, S. A., Schenten, D., Thomas Wunderlich, F., Pope, S. D., Gao, Y., Hoshi, N., Yu, S., Yan, X., Lee, H. K., Pasman, L., Brodsky, I., Yordy, B., Zhao, H., Brüning, J. & Medzhitov, R., May 19 2014, In : eLife. 2014, 3, e01949.

Research output: Contribution to journalArticle

3 Scopus citations

Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness

Pickard, J. M., Maurice, C. F., Kinnebrew, M. A., Abt, M. C., Schenten, D., Golovkina, T. V., Bogatyrev, S. R., Ismagilov, R. F., Pamer, E. G., Turnbaugh, P. J. & Chervonsky, A. V., Oct 1 2014, In : Nature. 514, 7524, p. 638-641 4 p.

Research output: Contribution to journalArticle

239 Scopus citations

Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells

Schenten, D., Nish, S. A., Yu, S., Yan, X., Lee, H., Brodsky, I., Pasman, L., Yordy, B., Wunderlich, F. T., Brüning, J. C., Zhao, H. & Medzhitov, R., Jan 16 2014, In : Immunity. 40, 1, p. 78-90 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

Signaling through the Adaptor Molecule MyD88 in CD4+ T Cells Is Required to Overcome Suppression by Regulatory T Cells

Schenten, D., Nish, S. A., Yu, S., Yan, X., Lee, H., Brodsky, I., Pasman, L., Yordy, B., Wunderlich, F. T., Brüning, J. C., Zhao, H. & Medzhitov, R., May 15 2014, In : Immunity. 40, 5, p. 814 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

T cell-intrinsic role of IL-6 signaling in primary and memory responses

Nish, S. A., Schenten, D., Wunderlich, T., Pope, S. D., Gao, Y., Hoshi, N., Yu, S., Yan, X., Lee, H. K., Pasman, L., Brodsky, I., Yordy, B., Zhao, H., Bruning, J. & Medzhitov, R., May 19 2014, In : eLife. 2014, 3, 01949.

Research output: Contribution to journalArticle

55 Scopus citations
2013

Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity

Palm, N. W., Rosenstein, R. K., Yu, S., Schenten, D., Florsheim, E. & Medzhitov, R., Nov 14 2013, In : Immunity. 39, 5, p. 976-985 10 p.

Research output: Contribution to journalArticle

99 Scopus citations

Signals via the Adaptor MyD88 in B Cells and DCs Make Distinct and Synergistic Contributions to Immune Activation and Tissue Damage in Lupus

Teichmann, L. L., Schenten, D., Medzhitov, R., Kashgarian, M. & Shlomchik, M. J., Mar 21 2013, In : Immunity. 38, 3, p. 528-540 13 p.

Research output: Contribution to journalArticle

88 Scopus citations
2012

Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells

Song, Y., Shen, H., Schenten, D., Shan, P., Lee, P. J. & Goldstein, D. R., Jan 2012, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 32, 1, p. 103-109 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions

Saribasak, H., Maul, R. W., Cao, Z., Yang, W. W., Schenten, D., Kracker, S. & Gearhart, P. J., Jun 4 2012, In : Journal of Experimental Medicine. 209, 6, p. 1075-1081 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis

Cataisson, C., Salcedo, R., Hakim, S., Moffitt B. Andrea, A., Wright, L., Yi, M., Stephens, R., Dai, R. M., Lyakh, L., Schenten, D., Yuspa, H. S. & Trinchieri, G., Aug 2012, In : Journal of Experimental Medicine. 209, 9, p. 1689-1702 14 p.

Research output: Contribution to journalArticle

70 Scopus citations

Langerhans cells require MyD88-dependent signals for Candida albicans response but not for contact hypersensitivity or migration

Haley, K., Igyártó, B. Z., Ortner, D., Bobr, A., Kashem, S., Schenten, D. & Kaplan, D. H., May 1 2012, In : Journal of Immunology. 188, 9, p. 4334-4339 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

Hoshi, N., Schenten, D., Nish, S. A., Walther, Z., Gagliani, N., Flavell, R. A., Reizis, B., Shen, Z., Fox, J. G., Iwasaki, A. & Medzhitov, R., 2012, In : Nature Communications. 3, 1120.

Research output: Contribution to journalArticle

87 Scopus citations
2011

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

Chu, Y., Vahl, J. C., Kumar, D., Heger, K., Bertossi, A., Wójtowicz, E., Soberon, V., Schenten, D., Mack, B., Reutelshófer, M., Beyaert, R., Amann, K., Van Loo, G. & Schmidt-Supprian, M., Feb 17 2011, In : Blood. 117, 7, p. 2227-2236 10 p.

Research output: Contribution to journalArticle

116 Scopus citations

The Control of Adaptive Immune Responses by the Innate Immune System

Schenten, D. & Medzhitov, R., 2011, Unknown Publisher. 38 p. (Advances in Immunology; vol. 109)

Research output: Book/ReportBook

152 Scopus citations
2009

MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity

Kleinridders, A., Schenten, D., Könner, A. C., Belgardt, B. F., Mauer, J., Okamura, T., Wunderlich, F. T., Medzhitov, R. & Brüning, J. C., Oct 7 2009, In : Cell Metabolism. 10, 4, p. 249-259 11 p.

Research output: Contribution to journalArticle

299 Scopus citations

Polζ ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability

Schenten, D., Kracker, S., Esposito, G., Franco, S., Klein, U., Murphy, M., Alt, F. W. & Rajewsky, K., Feb 16 2009, In : Journal of Experimental Medicine. 206, 2, p. 477-490 14 p.

Research output: Contribution to journalArticle

49 Scopus citations
2006

M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice

Schenten, D., Egert, A., Pasparakis, M. & Rajewsky, K., Jun 15 2006, In : Blood. 107, 12, p. 4849-4856 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2002

DNA polymerase K deficiency does not affect somatic hypermutation in mice

Schenten, D., Gerlach, V. L., Guo, C., Velasco-Miguel, S., Hladik, C. L., White, C. L., Friedberg, E. C., Rajewsky, K. & Esposito, G., Nov 2002, In : European Journal of Immunology. 32, 11, p. 3152-3160 9 p.

Research output: Contribution to journalArticle

114 Scopus citations
2000
105 Scopus citations
1999

Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo

Etemad-Moghadam, B., Sun, Y., Nicholson, E. K., Karlsson, G. B., Schenten, D. & Sodroski, J., 1999, In : Journal of Virology. 73, 10, p. 8873-8879 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

Effects of soluble CD4 on simian immunodeficiency virus infection of CD4-positive and CD4-negative cells

Schenten, D., Marcon, L., Karlsson, G. B., Parolin, C., Kodama, T., Gerard, N. & Sodroski, J., 1999, In : Journal of Virology. 73, 7, p. 5373-5380 8 p.

Research output: Contribution to journalArticle

47 Scopus citations
1998

Characterization of simian-human immunodeficiency virus envelope glycoprotein epitopes recognized by neutralizing antibodies from infected monkeys

Etemad-Moghadam, B., Karlsson, G. B., Halloran, M., Sun, Y., Schenten, D., Fernandes, M., Letvin, N. L. & Sodroski, J., 1998, In : Journal of Virology. 72, 10, p. 8437-8445 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques

Karlsson, G. B., Halloran, M., Schenten, D., Lee, J., Racz, P., Tenner-Racz, K., Manola, J., Gelman, R., Etemad-Moghadam, B., Desjardins, E., Wyatt, R., Gerard, N. P., Marcon, L., Margolin, D., Fanton, J., Axthelm, M. K., Letvin, N. L. & Sodroski, J., Sep 21 1998, In : Journal of Experimental Medicine. 188, 6, p. 1159-1171 13 p.

Research output: Contribution to journalArticle

93 Scopus citations