Donato Romagnolo

  • 1426 Citations
  • 22 h-Index
1990 …2019
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Research Output 1990 2019

  • 1426 Citations
  • 22 h-Index
  • 49 Article
  • 2 Chapter
  • 2 Review article
2019
1 Citation (Scopus)
Tamoxifen
Heterografts
Estrogen Receptors
Methylation
Down-Regulation
Open Access
Triple Negative Breast Neoplasms
Aryl Hydrocarbon Receptors
Genistein
genistein
Epigenomics
3 Citations (Scopus)

N-6 linoleic acid induces epigenetics alterations associated with colonic inflammation and cancer

Romagnolo, D., Donovan, M. G., Doetschman, T. C. & Selmin, O., Jan 1 2019, In : Nutrients. 11, 1, 171.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
bile acids
Linoleic Acid
Epigenomics
epigenetics
2018
2 Citations (Scopus)

Aryl Hydrocarbon Receptor Diet and Breast Cancer Risk

Donovan, M. G., Selmin, O. & Romagnolo, D., Jun 1 2018, In : The Yale journal of biology and medicine. 91, 2, p. 105-127 23 p.

Research output: Contribution to journalReview article

Aryl Hydrocarbon Receptors
Nutrition
Breast Neoplasms
Diet
Food
2017
8 Citations (Scopus)
Open Access
Aromatic Hydrocarbons
aromatic hydrocarbons
Genistein
cytosine
Cytosine
26 Citations (Scopus)

Mediterranean Diet and Prevention of Chronic Diseases

Romagnolo, D. & Selmin, O., Sep 1 2017, In : Nutrition Today. 52, 5, p. 208-222 15 p.

Research output: Contribution to journalArticle

Mediterranean Diet
Chronic Disease
Mediterranean Region
Nutrition Policy
Explosions
2016
19 Citations (Scopus)

Epigenetics of breast cancer: Modifying role of environmental and bioactive food compounds

Romagnolo, D., Daniels, K. D., Grunwald, J. T., Ramos, S. A., Propper, C. R. & Selmin, O., Jun 1 2016, In : Molecular Nutrition and Food Research. 60, 6, p. 1310-1329 20 p.

Research output: Contribution to journalReview article

Epigenomics
epigenetics
breast neoplasms
tumor suppressor genes
Breast Neoplasms
15 Citations (Scopus)
Adenomatous Polyposis Coli
Bile Acids and Salts
Colonic Neoplasms
Colon
Mucous Membrane
2015
17 Citations (Scopus)

Brca1 as target for breast cancer prevention and therapy

Romagnolo, A. P. G., Romagnolo, D. & Selmin, O., Jan 1 2015, In : Anti-Cancer Agents in Medicinal Chemistry. 15, 1, p. 4-14 11 p.

Research output: Contribution to journalArticle

BRCA1 Protein
Breast Neoplasms
Therapeutics
Neoplasms
Mutation
7 Citations (Scopus)
Aromatic Hydrocarbons
Carcinogenesis
Breast
Biomarkers
Breast Neoplasms
47 Citations (Scopus)
Aromatic Hydrocarbons
Aryl Hydrocarbon Receptors
Breast
Breast Neoplasms
Neoplasm Genes
2014
20 Citations (Scopus)

Nuclear receptors and epigenetic regulation: Opportunities for nutritional targeting and disease prevention

Romagnolo, D., Zempleni, J. & Selmin, O., 2014, In : Advances in Nutrition. 5, 4, p. 373-385 13 p.

Research output: Contribution to journalArticle

disease prevention
Cytoplasmic and Nuclear Receptors
Epigenomics
epigenetics
receptors
2012
39 Citations (Scopus)
Aromatic Hydrocarbons
MCF-7 Cells
Ligands
Xenobiotics
Transcription
185 Citations (Scopus)

Flavonoids and Cancer Prevention: A Review of the Evidence

Romagnolo, D. & Selmin, O., Jul 2012, In : Journal of Nutrition in Gerontology and Geriatrics. 31, 3, p. 206-238 33 p.

Research output: Contribution to journalArticle

Flavonoids
Neoplasms
Epidemiologic Studies
Diet
Flavanones
3 Citations (Scopus)

Nutritional regulation of epigenetic changes

Romagnolo, D., Dashwood, R., Stover, P. J., Waterland, R. A. & Ziegler, T. R., Sep 2012, In : Advances in Nutrition. 3, 5, p. 749-750 2 p.

Research output: Contribution to journalArticle

Genetic Epigenesis
Epigenomics
epigenetics
Diet
diet
6 Citations (Scopus)

Opportunities and challenges for nutritional proteomics in cancer prevention

Romagnolo, D. & Milner, J. A., Jul 2012, In : Journal of Nutrition. 142, 7

Research output: Contribution to journalArticle

Proteomics
Neoplasms
Food
Proteins
Research
10 Citations (Scopus)

Phytoalexins in cancer prevention

Romagnolo, D., Davis, C. D. & Milner, J. A., Jun 1 2012, In : Frontiers in Bioscience. 17, 6, p. 2035-2058 24 p.

Research output: Contribution to journalArticle

Neoplasms
Phase II Metabolic Detoxication
Agrochemicals
Biological Phenomena
Signal transduction
4 Citations (Scopus)
Proteomics
Biological Availability
Chronic Disease
Fatty Acids
Neoplasms
2011

Lactation: Galactopoiesis, Seasonal Effects

Collier, R. J., Romagnolo, D. & Baumgard, L. H., Jan 1 2011, Encyclopedia of Dairy Sciences: Second Edition. Elsevier Inc., p. 38-44 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

milk composition
Lactation
milk yield
Milk
lactation
24 Citations (Scopus)

Trichloroethylene induces methylation of the Serca2 promoter in H9c2 cells and embryonic heart

Palbykin, B., Borg, J., Caldwell, P. T., Rowles, J., Papoutsis, A. J., Romagnolo, D. & Selmin, O., Sep 2011, In : Cardiovascular Toxicology. 11, 3, p. 204-214 11 p.

Research output: Contribution to journalArticle

Trichloroethylene
Methylation
Genetic Promoter Regions
DNA Methylation
Cardiac Myoblasts
2010
15 Citations (Scopus)

Nutritional targeting of cyclooxygenase-2 for colon cancer prevention

Romagnolo, D., Papoutsis, A. J. & Selmin, O., 2010, In : Inflammation and Allergy - Drug Targets. 9, 3, p. 181-191 11 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Colonic Neoplasms
Cyclooxygenase 2 Inhibitors
Food
Colorectal Neoplasms
84 Citations (Scopus)

Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells

Papoutsis, A. J., Lamore, S. D., Wondrak, G. T., Selmin, O. & Romagnolo, D., Sep 2010, In : Journal of Nutrition. 140, 9, p. 1607-1614 8 p.

Research output: Contribution to journalArticle

Aromatic Hydrocarbons
Epigenomics
Breast Neoplasms
DNA Breaks
Methyltransferases
2009
5 Citations (Scopus)

Health Benefits of Traditional culinary and Medicinal Mediterranean Plants

Degner, S. C., Papoutsis, A. J. & Romagnolo, D., 2009, Complementary and Alternative Therapies and the Aging Population. Elsevier Inc., p. 541-562 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Insurance Benefits
Medicinal Plants
Chamomile
Mediterranean Region
Mediterranean Diet
67 Citations (Scopus)
Aryl Hydrocarbon Receptors
Cyclooxygenase 2
Breast Neoplasms
Xenobiotics
Histones
2008
25 Citations (Scopus)

Involvement of a specificity proteins-binding element in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene

Hockings, J. K., Degner, S. C., Morgan, S. S., Kemp, M. Q. & Romagnolo, D., Mar 31 2008, In : Breast Cancer Research. 10, 2, R29.

Research output: Contribution to journalArticle

BRCA1 Gene
Protein Binding
Estrogens
Transcription Factor AP-1
Response Elements
63 Citations (Scopus)

Rosmarinic acid antagonizes activator protein-1-dependent activation of cyclooxygenase-2 expression in human cancer and nonmalignant cell lines

Scheckel, K. A., Degner, S. C. & Romagnolo, D., Nov 2008, In : Journal of Nutrition. 138, 11, p. 2098-2105 8 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Cyclooxygenase 2
Cell Line
Neoplasms
Tetradecanoylphorbol Acetate
2007
31 Citations (Scopus)

Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer MCF-7 cells: Repressive effects of conjugated linoleic acid

Degner, S. C., Kemp, M. Q., Hockings, J. K. & Romagnolo, D., 2007, In : Nutrition and Cancer. 59, 2, p. 248-257 10 p.

Research output: Contribution to journalArticle

Conjugated Linoleic Acids
Aromatic Hydrocarbons
aromatic hydrocarbons
MCF-7 Cells
prostaglandin synthase
2006
44 Citations (Scopus)

Conjugated linoleic acid attenuates cyclooxygenase-2 transcriptional activity via an anti-AP-1 mechanism in MCF-7 breast cancer cells

Degner, S. C., Kemp, M. Q., Bowden, G. T. & Romagnolo, D., Feb 2006, In : Journal of Nutrition. 136, 2, p. 421-427 7 p.

Research output: Contribution to journalArticle

Conjugated Linoleic Acids
Transcription Factor AP-1
prostaglandin synthase
Cyclooxygenase 2
conjugated linoleic acid
14 Citations (Scopus)
Isocitrate Dehydrogenase
NADP
Prolactin
Breast
Epithelium
8 Citations (Scopus)

Induction of the transferrin receptor gene by benzo[a]pyrene in breast cancer MCF-7 cells: Potential as a biomarker of PAH exposure

Kemp, M. Q., Liu, W., Thorne, P. A., Kane, M. D., Selmin, O. & Romagnolo, D., Aug 2006, In : Environmental and Molecular Mutagenesis. 47, 7, p. 518-526 9 p.

Research output: Contribution to journalArticle

Transferrin Receptors
Benzo(a)pyrene
Polycyclic Aromatic Hydrocarbons
MCF-7 Cells
Biomarkers
1 Citation (Scopus)

Role of dietary xenobiotics-gene interactions in carcinogenesis: Protective effects of nutritional factors

Romagnolo, D., Degner, S. C., Kemp, M. Q., Hockings, J. K. & Selmin, O., Aug 2006, In : Current Nutrition and Food Science. 2, 3, p. 205-214 10 p.

Research output: Contribution to journalArticle

gene interaction
Polycyclic Aromatic Hydrocarbons
Xenobiotics
polycyclic aromatic hydrocarbons
xenobiotics
58 Citations (Scopus)

The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen

Hockings, J. K., Thorne, P. A., Kemp, M. Q., Morgan, S. S., Selmin, O. & Romagnolo, D., Feb 15 2006, In : Cancer Research. 66, 4, p. 2224-2232 9 p.

Research output: Contribution to journalArticle

Aromatic Hydrocarbons
Transcriptional Activation
Estrogens
Ligands
Estrogen Receptors
15 Citations (Scopus)
isocitrate dehydrogenase (NADP)
Conjugated Linoleic Acids
conjugated linoleic acid
prolactin
Prolactin
2005
60 Citations (Scopus)

An estrogen receptor-α/p300 complex activates the BRCA-1 promoter at an AP-1 site that binds Jun/Fos transcription factors: Repressive effects of p53 on BRCA-1 transcription

Jeffy, B. D., Hockings, J. K., Kemp, M. Q., Morgan, S. S., Hager, J. A., Beliakoff, J., Whitesell, L. J., Bowden, G. T. & Romagnolo, D., Sep 2005, In : Neoplasia. 7, 9, p. 873-882 10 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Estrogen Receptors
Transcription Factors
Estrogens
Breast
17 Citations (Scopus)

Transcriptional activation of the membrane-bound progesterone receptor (mPR) by dioxin, in endocrine-responsive tissues

Selmin, O., Thorne, P. A., Blachere, F. M., Johnson, P. D. & Romagnolo, D., Feb 2005, In : Molecular Reproduction and Development. 70, 2, p. 166-174 9 p.

Research output: Contribution to journalArticle

Dioxins
Progesterone Receptors
Transcriptional Activation
Membranes
Liver
2003
73 Citations (Scopus)
G1 Phase Cell Cycle Checkpoints
Conjugated Linoleic Acids
conjugated linoleic acid
colorectal neoplasms
breast neoplasms
18 Citations (Scopus)

Deoxycholate, an endogenous tumor promoter and DNA damaging agent, modulates BRCA-1 expression in apoptosis-sensitive epithelial cells: Loss of BRCA-1 expression in colonic adenocarcinomas

Romagnolo, D., Chirnomas, R. B., Ku, J., Jeffy, B. D., Payne, C. M., Holubec, H., Ramsey, L., Bernstein, H., Bernstein, C., Kunke, K., Bhattacharyya, A. K., Warneke, J. A. & Garewal, H., 2003, In : Nutrition and Cancer. 46, 1, p. 82-92 11 p.

Research output: Contribution to journalArticle

deoxycholic acid
Deoxycholic Acid
adenocarcinoma
Carcinogens
Adenocarcinoma
2002
40 Citations (Scopus)
Aromatic Hydrocarbons
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Benzo(a)pyrene
Messenger RNA
Cytochrome P-450 CYP1A1
58 Citations (Scopus)

Epigenetics of breast cancer: Polycyclic aromatic hydrocarbons as risk factors

Jeffy, B. D., Chirnomas, R. B. & Romagnolo, D., 2002, In : Environmental and Molecular Mutagenesis. 39, 2-3, p. 235-244 10 p.

Research output: Contribution to journalArticle

Polycyclic Aromatic Hydrocarbons
risk factor
Epigenomics
cancer
PAH
2001
17 Citations (Scopus)

Response of Holstein and Brown Swiss cows fed alfalfa hay-based diets to supplemental methionine at two stages of lactation

Samuelson, D. J., Denise, S. K., Roffler, R., Ax, R. L., Armstrong, D. V. & Romagnolo, D., Apr 2001, In : Journal of Dairy Science. 84, 4, p. 917-928 12 p.

Research output: Contribution to journalArticle

Brown Swiss
Medicago sativa
lactation stage
alfalfa hay
Lactation
7 Citations (Scopus)

Transcriptional activation of the gp91phox NADPH oxidase subunit by TPA in HL-60 cells

Samuelson, D. J., Powell, M. B., Lluria-Prevatt, M. & Romagnolo, D., 2001, In : Journal of Leukocyte Biology. 69, 1, p. 161-168 8 p.

Research output: Contribution to journalArticle

NADPH Oxidase
HL-60 Cells
Transcriptional Activation
Acetates
Reactive Oxygen Species
2000
52 Citations (Scopus)

Disruption of cell cycle kinetics by benzo[a]pyrene: Inverse expression patterns of BRCA-1 and p53 in MCF-7 cells arrested in S and G2

Jeffy, B. D., Chen, E. J., Gudas, J. M. & Romagnolo, D., 2000, In : Neoplasia. 2, 5, p. 460-470 11 p.

Research output: Contribution to journalArticle

Benzo(a)pyrene
MCF-7 Cells
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Cell Cycle
Aromatic Hydrocarbons
1999
38 Citations (Scopus)

Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide

Jeffy, B. D., Schultz, E. U., Selmin, O., Gudas, J. M., Bowden, G. T. & Romagnolo, D., 1999, In : Molecular Carcinogenesis. 26, 2, p. 100-118 19 p.

Research output: Contribution to journalArticle

Benzo(a)pyrene
Epoxy Compounds
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Messenger RNA
Aromatic Hydrocarbons
1998
52 Citations (Scopus)

Estrogen upregulation of BRCA1 expression with no effect on localization

Romagnolo, D., Annab, L. A., Thompson, T. E., Risinger, J. I., Terry, L. A., Barrett, J. C. & Afshari, C. A., Jun 1998, In : Molecular Carcinogenesis. 22, 2, p. 102-109 8 p.

Research output: Contribution to journalArticle

Estrogens
Up-Regulation
BRCA1 Protein
Estrogen Receptors
Ovarian Neoplasms
1994
24 Citations (Scopus)

Electrophoretic analysis of ruminal degradability of corn proteins.

Romagnolo, D., Polan, C. E. & Barbeau, W. E., Apr 1994, In : Journal of Dairy Science. 77, 4, p. 1093-1099 7 p.

Research output: Contribution to journalArticle

corn protein
corn gluten meal
globulins
zein
glutelins
29 Citations (Scopus)

IGF-I-Induced IGFBP-3 potentiates the mitogenic actions of IGF-I in mammary epithelial MD-IGF-I cells

Romagnolo, D., Michael Akers, R., Byatt, J. C., Wong, E. A. & Turner, J. D., 1994, In : Molecular and Cellular Endocrinology. 102, 1-2, p. 131-139 9 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 3
Insulin-Like Growth Factor I
Carrier Proteins
Breast
T-cells
10 Citations (Scopus)

Regulation of expression of IGF-I-induced IGFBP-3 and IGF-I-receptor by constitutive vs regulated expression of recombinant IGF-I in transfected mammary epithelial cells

Romagnolo, D., Akers, R. M., Byatt, J. C., Wong, E. A. & Turner, J. D., 1994, In : Endocrine. 2, 5, p. 375-384 10 p.

Research output: Contribution to journalArticle

IGF Type 1 Receptor
Insulin-Like Growth Factor Binding Protein 3
Insulin-Like Growth Factor I
Breast
Epithelial Cells

Renovating Italian science [1]

Romagnolo, D. & Selmin, O., 1994, In : Science. 263, 5144, p. 1669 1 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The mammary gland: Protein factory of the future

Romagnolo, D. & DiAugustine, R. P., 1994, In : Environmental Health Perspectives. 102, 8, p. 644-646 3 p.

Research output: Contribution to journalArticle

Industrial plants
protein
Proteins
2 Citations (Scopus)

Transgenic approaches for modifying the mammary gland to produce therapeutic proteins

Romagnolo, D. & DiAugustine, R. P., 1994, In : Environmental Health Perspectives. 102, 10, p. 846-851 6 p.

Research output: Contribution to journalArticle

Human Mammary Glands
Milk Proteins
Genetically Modified Animals
Breast
protein