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  • 2 Similar Profiles
Proteins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Chaperonins Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
Biological Products Medicine & Life Sciences
Chemical activation Chemical Compounds
Amino Acids Medicine & Life Sciences
Therapeutics Medicine & Life Sciences

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Projects 2004 2018

Arsenic
Autophagy
Proteins
Quality Control
Arsenicals

Using chemical genetics to explore GroEL function

Chapman, E.

National Institutes of Health

2/1/041/31/07

Project: Research projectPostdoctoral Individual National Research Service Award

Peptides
Chaperonins
Escherichia coli
Inclusion Bodies
Protein Folding

Research Output 1995 2018

  • 1351 Citations
  • 20 h-Index
  • 46 Article
  • 3 Review article
  • 2 Chapter

The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer

Tao, S., Rojo de la Vega, M., Chapman, E., Ooi, A. & Zhang, D. D. Feb 1 2018 In : Molecular Carcinogenesis. 57, 2, p. 182-192 11 p.

Research output: Research - peer-reviewArticle

Lung Neoplasms
Neoplasms
Oncogenes
Carcinogenesis
Lung
2 Citations
Endophytes
Protein Tyrosine Phosphatases
Epigenomics
verruculide B
Metabolites

Arsenic Compromises Both p97 and Proteasome Functions

Tillotson, J., Zerio, C. J., Harder, B., Ambrose, A. J., Jung, K. S., Kang, M., Zhang, D. D. & Chapman, E. Jul 17 2017 In : Chemical Research in Toxicology. 30, 7, p. 1508-1514 7 p.

Research output: Research - peer-reviewArticle

Arsenic
Proteasome Endopeptidase Complex
Proteins
Quality Control
Quality control

ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A

Tillotson, J., Kedzior, M., Guimarães, L., Ross, A. B., Peters, T. L., Ambrose, A. J., Schmidlin, C. J., Zhang, D. D., Costa-Lotufo, L. V., Rodríguez, A. D., Schatz, J. H. & Chapman, E. 2017 In : Bioorganic and Medicinal Chemistry Letters. 27, 17, p. 4082-4085 4 p.

Research output: Research - peer-reviewArticle

Biological Products
Adenosine Triphosphatases
Adenosine Triphosphate
Neoplasms
Cells
6 Citations

Brusatol overcomes chemoresistance through inhibition of protein translation

Harder, B., Tian, W., La Clair, J. J., Tan, A. C., Ooi, A., Chapman, E. & Zhang, D. D. May 1 2017 In : Molecular Carcinogenesis. 56, 5, p. 1493-1500 8 p.

Research output: Research - peer-reviewArticle

Protein Biosynthesis
Neoplasms
brusatol
Therapeutics
Xenobiotics