• 1617 Citations
  • 22 h-Index
19952018
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  • 1 Similar Profiles
Chaperonins Medicine & Life Sciences
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Sulfotransferases Chemical Compounds
Proteins Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences

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Projects 2004 2018

Arsenic
Autophagy
Arsenicals
Quality Control
Foot Diseases

Using chemical genetics to explore GroEL function

Chapman, E.

National Institutes of Health

2/1/041/31/07

Project: Research projectPostdoctoral Individual National Research Service Award

Chaperonins
Peptides
Escherichia coli
Inclusion Bodies
Protein Folding

Research Output 1995 2018

  • 1617 Citations
  • 22 h-Index
  • 52 Article
  • 3 Review article
  • 2 Chapter

A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B)

François-Moutal, L., Jahanbakhsh, S., Nelson, A. D. L., Ray, D., Scott, D. D., Hennefarth, M. R., Moutal, A., Perez-Miller, S., Ambrose, A. J., Al-Shamari, A., Coursodon, P., Meechoovet, B., Reiman, R., Lyons, E. H., Beilstein, M. A., Chapman, E., Morris, Q. D., Van Keuren-Jensen, K., Hughes, T. R., Khanna, R. & 4 othersKoehler, C., Jen, J., Gokhale, V. & Khanna, M., Jan 1 2018, (Accepted/In press) In : ACS Chemical Biology.

Research output: Contribution to journalArticle

RNA
Thermophoresis
Zebrafish
Molecules
Exosome Multienzyme Ribonuclease Complex

Increased O-GlcNAcylation of SNAP29 drives arsenicinduced autophagic dysfunction

Dodson, M., Liu, P., Jiang, T., Ambrose, A. J., Luo, G., de la Vega, M. R., Cholanians, A. B., Wong, P. K., Chapman, E. & Zhang, D., Jun 1 2018, In : Molecular and Cellular Biology. 38, 11, e00595-17.

Research output: Contribution to journalArticle

Arsenic
SNARE Proteins
Autophagy
Lysosomes
Clustered Regularly Interspaced Short Palindromic Repeats
1 Citations

Low-level arsenic causes proteotoxic stress and not oxidative stress

Dodson, M., de la Vega, M. R., Harder, B., Castro-Portuguez, R., Rodrigues, S. D., Wong, P. K., Chapman, E. & Zhang, D., Feb 15 2018, In : Toxicology and Applied Pharmacology. 341, p. 106-113 8 p.

Research output: Contribution to journalArticle

Oxidative stress
Arsenic
Oxidative Stress
Autophagy
Pathology
6 Citations

NRF2 and the Hallmarks of Cancer

Rojo de la Vega, M., Chapman, E. & Zhang, D., Jan 1 2018, (Accepted/In press) In : Cancer Cell.

Research output: Contribution to journalArticle

Neoplasms
Transcription Factors
Antioxidants
Neoplasm Metastasis
Therapeutics

Sulfonamido-2-arylbenzoxazole GroEL/ES inhibitors are potent antibacterials against methicillin-resistant Staphylococcus aureus (MRSA)

Abdeen, S., Kunkle, T., Salim, N., Ray, A. M., Mammadova, N., Summers, C., Stevens, M., Ambrose, A., Park, Y., Schultz, P. G., Horwich, A. L., Hoang, Q., Chapman, E. & Johnson, S. M., Jan 1 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Acinetobacter baumannii
Enterococcus faecium
Klebsiella pneumoniae
Methicillin-Resistant Staphylococcus aureus
Pseudomonas aeruginosa