Evan C Unger

  • 6986 Citations
  • 45 h-Index
1985 …2019

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Article
2019

Imaging assessment of cardioprotection mediated by a dodecafluoropentane oxygen-carrier administered during myocardial infarction

Liu, Z., Barber, C., Gupta, A., Wan, L., Won, Y. W., Furenlid, L. R., Chen, Q., Desai, A. A., Zhao, M., Bull, D. A., Unger, E. C. & Martin, D. R., Mar 2019, In : Nuclear Medicine and Biology. 70, p. 67-77 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

In vitro model to compare the oxygen offloading behaviour of dodecafluoropentane emulsion (DDFPe)

Jayaraman, M. S., Graham, K. & Unger, E. C., Dec 4 2019, In : Artificial Cells, Nanomedicine and Biotechnology. 47, 1, p. 783-789 7 p.

Research output: Contribution to journalArticle

Open Access
2018

Endothelial vascular cell adhesion molecule 1 is a marker for high-risk carotid plaques and target for ultrasound molecular imaging

Weinkauf, C. C., Concha-Moore, K., Lindner, J. R., Marinelli, E. R., Hadinger, K. P., Bhattacharjee, S., Berman, S. S., Goshima, K., Leon, L. R., Matsunaga, T. O. & Unger, E., Dec 2018, In : Journal of vascular surgery. 68, 6, p. 105S-113S

Research output: Contribution to journalArticle

4 Scopus citations

Ultrasound Molecular Imaging of Atherosclerosis Using Small-Peptide Targeting Ligands Against Endothelial Markers of Inflammation and Oxidative Stress

Moccetti, F., Weinkauf, C. C., Davidson, B. P., Belcik, J. T., Marinelli, E. R., Unger, E. & Lindner, J. R., Jun 2018, In : Ultrasound in Medicine and Biology. 44, 6, p. 1155-1163 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Radiosensitization of Hs-766T pancreatic tumor xenografts in mice dosed with dodecafluoropentane nano-emulsion-preliminary findings

Johnson, J. L. H., Leos, R. A., Baker, A. F. & Unger, E. C., Feb 1 2015, In : Journal of Biomedical Nanotechnology. 11, 2, p. 274-281 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014
3 Scopus citations

Sonothrombolysis in acute stroke and myocardial infarction: A systematic review

Roos, S. S., Juffermans, L. M. L., Slikkerveer, J., Unger, E. C., Porter, T. R. & Kampa, O., Jan 1 2014, In : IJC Heart and Vessels. 4, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

13 Scopus citations
2013

Diagnostic Ultrasound Induced Inertial Cavitation to Non-Invasively Restore Coronary and Microvascular Flow in Acute Myocardial Infarction

Xie, F., Gao, S., Wu, J., Lof, J., Radio, S., Vignon, F., Shi, W., Powers, J., Unger, E., Everbach, E. C., Liu, J. & Porter, T. R., Jul 29 2013, In : PloS one. 8, 7, e69780.

Research output: Contribution to journalArticle

21 Scopus citations
2012

Control of solid tumor growth in mice using EGF receptor-targeted RNA replicase-based plasmid DNA

Rodriguez, B. L., Li, X., Kiguchi, K., Digiovanni, J., Unger, E. C. & Cui, Z., Apr 1 2012, In : Nanomedicine. 7, 4, p. 475-491 17 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dodecafluoropentane emulsion decreases infarct volume in a rabbit ischemic stroke model

Culp, W. C., Woods, S. D., Skinner, R. D., Brown, A. T., Lowery, J. D., Johnson, J. L. H., Unger, E. C., Hennings, L. J., Borrelli, M. J. & Roberson, P. K., Jan 1 2012, In : Journal of Vascular and Interventional Radiology. 23, 1, p. 116-121 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
2011

Coronary and microvascular thrombolysis with guided diagnostic ultrasound and microbubbles in acute ST segment elevation myocardial infarction

Xie, F., Slikkerveer, J., Gao, S., Lof, J., Kamp, O., Unger, E., Radio, S., Matsunaga, T. & Porter, T. R., Dec 1 2011, In : Journal of the American Society of Echocardiography. 24, 12, p. 1400-1408 9 p.

Research output: Contribution to journalArticle

38 Scopus citations
2009
38 Scopus citations

Transcranial ultrasound in clinical sonothrombolysis (TUCSON) trial

Molina, C. A., Barreto, A. D., Tsivgoulis, G., Sierzenski, P., Malkoff, M. D., Rubiera, M., Gonzales, N., Mikulik, R., Pate, G., Ostrem, J., Singleton, W., Manvelian, G., Unger, E. C., Grotta, J. C., Schellinger, P. D. & Alexandrov, A. V., Jul 1 2009, In : Annals of Neurology. 66, 1, p. 28-38 11 p.

Research output: Contribution to journalArticle

175 Scopus citations
2007
1 Scopus citations
2006

Treatment of deeply located acute intravascular thrombi with therapeutic ultrasound guided by diagnostic ultrasound and intravenous microbubbles

Tsutsui, J. M., Xie, F., Johanning, J., Lof, J., Cory, B., He, A., Thomas, L., Matsunaga, T., Unger, E. & Porter, T. R., Sep 2006, In : Journal of Ultrasound in Medicine. 25, 9, p. 1161-1168 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
2005

Effectiveness of lipid microbubbles and ultrasound in declotting thrombosis

Xie, F., Tsutsui, J. M., Lof, J., Unger, E. C., Johanning, J., Culp, W. C., Matsunaga, T. & Porter, T. R., Jul 1 2005, In : Ultrasound in Medicine and Biology. 31, 7, p. 979-985 7 p.

Research output: Contribution to journalArticle

103 Scopus citations
2004

DNA delivery to cells in culture using ultrasound.

McCreery, T. P., Sweitzer, R. H. & Unger, E. C., 2004, In : Methods in molecular biology (Clifton, N.J.). 245, p. 287-292 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

DNA delivery to cells in vivo by ultrasound.

McCreery, T. P., Sweitzer, R. H., Unger, E. C. & Sullivan, S., 2004, In : Methods in molecular biology (Clifton, N.J.). 245, p. 293-298 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Therapeutic applications of lipid-coated microbubbles

Unger, E. C., Porter, T., Culp, W., Labell, R., Matsunaga, T. & Zutshi, R., May 7 2004, In : Advanced Drug Delivery Reviews. 56, 9, p. 1291-1314 24 p.

Research output: Contribution to journalArticle

450 Scopus citations
2003

Microbubbles in molecular imaging and therapy

Unger, E., Matsunaga, T. O., Schumann, P. A. & Zutshi, R., Apr 1 2003, In : MedicaMundi. 47, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

MR imaging of arrhythmogenic right ventricular cardiomyopathy: Morphologic findings and interobserver reliability

Bluemke, D. A., Krupinski, E. A., Ovitt, T., Gear, K., Unger, E., Axel, L., Boxt, L. M., Casolo, G., Ferrari, V. A., Funaki, B., Globits, S., Higgins, C. B., Julsrud, P., Lipton, M., Mawson, J., Nygren, A., Pennell, D. J., Stillman, A., White, R. D., Wichter, T. & 1 others, Marcus, F., Jun 30 2003, In : Cardiology. 99, 3, p. 153-162 10 p.

Research output: Contribution to journalArticle

162 Scopus citations

Nanoparticle drug delivery system for intravenous delivery of topoisomerase inhibitors

Williams, J., Lansdown, R., Sweitzer, R., Romanowski, M., LaBell, R., Ramaswami, R. & Unger, E., Aug 28 2003, In : Journal of Controlled Release. 91, 1-2, p. 167-172 6 p.

Research output: Contribution to journalArticle

113 Scopus citations
2002

Biomedical implications of a thrombus-specific US contrast agent

Unger, E. C., Matsunaga, T. O., McCreery, T. P. & Sweitzer, R. H., Jan 1 2002, In : Academic radiology. 9, SUPPL. 1, p. S56-S57

Research output: Contribution to journalArticle

4 Scopus citations

Targeted-microbubble binding selectively to GPIIb IIIa receptors of platelet thrombi

Schumann, P. A., Christiansen, J. P., Quigley, R. M., McCreery, T. P., Sweitzer, R. H., Unger, E. C., Lindner, J. R. & Matsunaga, T. O., Nov 1 2002, In : Investigative Radiology. 37, 11, p. 587-593 7 p.

Research output: Contribution to journalArticle

182 Scopus citations

Therapeutic applications of microbubbles

Unger, E. C., Matsunaga, T. O., McCreery, T., Schumann, P., Sweitzer, R. & Quigley, R., Apr 23 2002, In : European Journal of Radiology. 42, 2, p. 160-168 9 p.

Research output: Contribution to journalArticle

243 Scopus citations

Ultrasound-mediated transfection of canine myocardium by intravenous administration of cationic microbubble-linked plasmid DNA

Vannan, M., McCreery, T., Li, P., Han, Z., Unger, E., Kuersten, B., Nabel, E. & Rajagopalan, S., Mar 2002, In : Journal of the American Society of Echocardiography. 15, 3, p. 214-218 5 p.

Research output: Contribution to journalArticle

99 Scopus citations
2001

Gene delivery using ultrasound contrast agents

Unger, E. C., Hersh, E., Vannan, M. & McCreery, T., Jan 1 2001, In : Echocardiography. 18, 4, p. 355-361 7 p.

Research output: Contribution to journalArticle

140 Scopus citations

Local drug and gene delivery through microbubbles

Unger, E. C., Hersh, E., Vannan, M., Matsunaga, T. O. & McCreery, T., Jan 1 2001, In : Progress in Cardiovascular Diseases. 44, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

244 Scopus citations
2000

Advances in imaging of lymph flow disorders

Witte, C. L., Witte, M. H., Unger, E. C., Williams, W. H., Bernas, M. J., McNeill, G. C. & Stazzone, A. M., Jan 1 2000, In : Radiographics. 20, 6, p. 1697-1719 23 p.

Research output: Contribution to journalArticle

121 Scopus citations

The use of a thrombus-specific ultrasound contrast agent to detect thrombus in arteriovenous fistulae

Unger, E., Metzger, P., Krupinski, E., Baker, M., Hulett, R., Gabaeff, D., Mills, J., Ihnat, D. & McCreery, T., Jan 18 2000, In : Investigative Radiology. 35, 1, p. 86-89 4 p.

Research output: Contribution to journalArticle

39 Scopus citations

Ultrasound enhancement of cationic lipid-mediated gene transfer to primary tumors following systemic administration

Anwer, K., Kao, G., Proctor, B., Anscombe, I., Florack, V., Earls, R., Wilson, E., McCreery, T., Unger, E., Rolland, A. & Sullivan, S. M., Jan 1 2000, In : Gene Therapy. 7, 21, p. 1833-1839 7 p.

Research output: Contribution to journalArticle

Open Access
144 Scopus citations
1999

Enhanced visualization of intravascular and left atrial appendage thrombus with the use of a thrombus-targeting ultrasonographic contrast agent (MRX-408A1): In vivo experimental echocardiographic studies

Takeuchi, M., Ogunyankin, K., Pandian, N. G., McCreery, T. P., Sweitzer, R. H., Caldwell, V. E., Unger, E. C., Avelar, E., Sheahan, M. & Connolly, R., Jan 1 1999, In : Journal of the American Society of Echocardiography. 12, 12, p. 1015-1021 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Gadolinium-containing copolymeric chelates - A new potential MR contrast agent

Unger, E. C., Shen, D., Wu, G., Stewart, L., Matsunaga, T. O. & Trouard, T. P., Aug 1 1999, In : Magnetic Resonance Materials in Physics, Biology and Medicine. 8, 3, p. 154-162 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Immunotherapy of advanced malignancy by direct gene transfer of an interleukin-2 DNA/DMRIE/DOPE lipid complex: Phase I/II experience

Galanis, E., Hersh, E. M., Stopeck, A. T., Gonzalez, R., Burch, P., Spier, C., Akporiaye, E. T., Rinehart, J. J., Edmonson, J., Sobol, R. E., Forscher, C., Sondak, V. K., Lewis, B. D., Unger, E. C., O'Driscoll, M., Selk, L. & Rubin, J., Oct 1999, In : Journal of Clinical Oncology. 17, 10, p. 3313-3323 11 p.

Research output: Contribution to journalArticle

92 Scopus citations
1998

Accuracy of CT biopsy: Laser guidance versus conventional freehand techniques

Pereles, F. S., Baker, M., Baldwin, R., Krupinski, E. & Unger, E. C., Jan 1 1998, In : Academic radiology. 5, 11 SUPPL. 3, p. 766-770 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Acoustically active lipospheres containing paclitaxel: A new therapeutic ultrasound contrast agent

Unger, E. C., McCreery, T. P., Sweitzer, R. H., Caldwell, V. E. & Wu, Y., Dec 1 1998, In : Investigative Radiology. 33, 12, p. 886-892 7 p.

Research output: Contribution to journalArticle

241 Scopus citations

Binding and lysing of blood clots using MRX-408

Wu, Y., Unger, E. C., McCreery, T. P., Sweitzer, R. H., Shen, D., Wu, G. & Vielhauer, M. D., Dec 1 1998, In : Investigative Radiology. 33, 12, p. 880-885 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

Evaluation of new thrombus-specific ultrasound contrast agent.

Wright, W. H., McCreery, T. P., Krupinski, E. A., Lund, P. J., Smyth, S. H., Baker, M. R., Hulett, R. L. & Unger, E. C., Apr 1998, In : Academic radiology. 5 Suppl 1, p. S240-242

Research output: Contribution to journalArticle

28 Scopus citations

In vitro studies of a new thrombus-specific ultrasound contrast agent

Unger, E. C., McCreery, T. P., Sweitzer, R. H., Shen, D. K. & Wu, G., Jun 18 1998, In : American Journal of Cardiology. 81, 12 A, p. 58G-61G

Research output: Contribution to journalArticle

130 Scopus citations

MRX 501: a novel ultrasound contrast agent with therapeutic properties.

Unger, E. C., McCreery, T., Sweitzer, R., Vielhauer, G., Wu, G., Shen, D. & Yellowhair, D., Apr 1998, In : Academic radiology. 5 Suppl 1, p. S247-249

Research output: Contribution to journalArticle

32 Scopus citations

Percutaneous sclerosis or excision of lymphangioma/ lymphangiectasia syndromes

Witte, C. L., Witte, M. H., Unger, E., Baker, M., Granstrom, P., Bernas, M. & Williams, W., Dec 1 1998, In : Lymphology. 31, 1 SUPPL., p. 396-399 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Potentials of a new laser guidance system for percutaneous musculoskeletal procedures

Pereles, F. S., Ozgur, H. T., Lund, P. J. & Unger, E. C., May 5 1998, In : Skeletal Radiology. 27, 1, p. 18-21 4 p.

Research output: Contribution to journalArticle

6 Scopus citations
1997

Aerosomes myocardial contrast echocardiography (MCE) accurately detects resting myocardial perfusion abnormalities post myocardial infarction

Gertz, E. W., Manspeaker, P., Fritz, T., Kaul, S. & Unger, E., Jan 1 1997, In : Ultrasound in Medicine and Biology. 23, Suppl 1, p. CAO 105

Research output: Contribution to journalArticle

2 Scopus citations

Human gene therapy for melanoma: CT-guided interstitial injection

Waddill, W., Wright, W., Unger, E., Stopeck, A., Akporiaye, E., Harris, D., Grogan, T., Schluter, S., Hersh, E. & Stahl, S., Jul 1997, In : American Journal of Roentgenology. 169, 1, p. 63-67 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Phase I clinical trials of MRX-115: A new ultrasound contrast agent

Fritz, T. A., Unger, E. C., Sutherland, G. & Sahn, D., Dec 1 1997, In : Investigative Radiology. 32, 12, p. 735-740 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Phase I study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in patients with metastatic melanoma

Stopeck, A. T., Hersh, E. M., Akporiaye, E. T., Harris, D. T., Grogan, T., Unger, E., Warneke, J., Schluter, S. F. & Stahl, S., Jan 1997, In : Journal of Clinical Oncology. 15, 1, p. 341-349 9 p.

Research output: Contribution to journalArticle

135 Scopus citations

Potentials of laser guidance system for percutaneous musculoskeletal procedures

Pereles, F. S., Ozgur, H. T., Lund, P. J. & Unger, E. C., Nov 1 1997, In : Skeletal Radiology. 26, 11, p. 650-653 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Ultrasonographic detection of testicular ischemia in a canine model using phospholipid coated microbubbles (MRX-115)

Metzger-Rose, C., Krupinski, E. A., Wright, W. H., Baker, M. R., McCreery, T. P., Barrette, T. R. & Unger, E. C., May 1997, In : Journal of Ultrasound in Medicine. 16, 5, p. 317-324 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Ultrasound enhances gene expression of liposomal transfection

Unger, E. C., McCreery, T. P. & Sweitzer, R. H., Dec 1 1997, In : Investigative Radiology. 32, 12, p. 723-727 5 p.

Research output: Contribution to journalArticle

142 Scopus citations
1996

Effect of phospholipid-coated microbubbles (MRX-115) on the detection of testicular ischemia in dogs.

Metzger-Rose, C., Wright, W. H., Baker, M. R., Krupinski, E. A., McCreery, T. P., Barrette, T. R. & Unger, E. C., Aug 1996, In : Academic radiology. 3 Suppl 2, p. S315-316

Research output: Contribution to journalArticle

3 Scopus citations