Evan M Hersh &ndash; Research Output

Ability of cell-sized beads bearing tumor cell membrane proteins to stimulate LAK cells to secrete interferon-γ and tumor necrosis factor-α¹

Chong, A. S. F., Pinkard, J. K., Lam, K. S., Scuderi, P., Hersh, E. M. & Grimes, W. J., Apr 15 1991, In : Cellular Immunology. 134, 1, p. 96-110 15 p.

Research output: Contribution to journal › Article

Lymphokine-Activated Killer Cells

Interferons

Membrane Proteins

Tumor Necrosis Factor-alpha

Neoplasms

20 Citations (Scopus)

Abnormal lymphocyte response to exogenous interleukin-2 in homosexuals with acquired immune deficiency syndrome (AIDS) and AIDS related complex (ARC)

Murray, J. L., Hersh, E. M., Reuben, J. M., Munn, C. G. & Mansell, P. W., 1985, In : Clinical and Experimental Immunology. 60, 1, p. 25-30 6 p.

Research output: Contribution to journal › Article

Interleukin-2

Acquired Immunodeficiency Syndrome

Lymphocytes

Prodromal Symptoms

Heterosexuality

4 Citations (Scopus)

Acquired immune deficiency syndrome: A new clinical entity

Hersh, E. M. & Mansell, P. W. A., Apr 1983, In : Clinical Immunology Newsletter. 4, 4, p. 39-43 5 p.

Research output: Contribution to journal › Article

Acquired Immunodeficiency Syndrome

7 Citations (Scopus)

Actinomycin-D plus 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamine (DTIC) with or without intravenous Corynebacterium parvum in metastatic malignant melanoma

Robidoux, A., Gutterman, J. U., Bodey, G. P. & Hersh, E. M., 1982, In : Cancer. 49, 11, p. 2246-2251 6 p.

Research output: Contribution to journal › Article

Propionibacterium acnes

Dactinomycin

Melanoma

Drug Therapy

Body Surface Area

28 Citations (Scopus)

Activation of cyclic nucleotide phosphodiesterase from isolated human peripheral blood lymphocytes by mitogenic agents

Epstein, P. M., Mills, J. S., Hersh, E. M., Strada, S. J. & Thompson, W. J., 1980, In : Cancer Research. 40, 2, p. 379-386 8 p.

Research output: Contribution to journal › Article

Cyclic Nucleotides

Phosphoric Diester Hydrolases

Phytohemagglutinins

Lymphocytes

Cyclic AMP

8 Citations (Scopus)

Activation of human lymphocyte high affinity cyclic AMP phosphodiesterase by culture with 1-methyl-3-isobutylxanthine

Thompson, W. J., Ross, C. P., Hersh, E. M., Epstein, P. M. & Strada, S. J., 1980, In : Journal of Cyclic Nucleotide Research. 6, 1, p. 25-36 12 p.

Research output: Contribution to journal › Article

1-Methyl-3-isobutylxanthine

Lymphocytes

Phosphoric Diester Hydrolases

Lymphocyte Activation

Cell culture

188 Citations (Scopus)

ACTIVE IMMUNOTHERAPY WITH B.C.G. FOR RECURRENT MALIGNANT MELANOMA

Gutterman, J. U., McBride, C., Freireich, E. J., Mavligit, G., Frei, E. & Hersh, E. M., Jun 2 1973, In : The Lancet. 301, 7814, p. 1208-1212 5 p.

Research output: Contribution to journal › Article

Active Immunotherapy

Mycobacterium bovis

Melanoma

Immunotherapy

Delayed Hypersensitivity

8 Citations (Scopus)

Active specific immunization with allogeneic leukemia associated antigens or irradiated allogeneic leukemia cells in acute leukemia

Ezaki, K., Hersh, E. M., Keating, M., Dyre, S., Hollinshead, A., McCredie, K. B., Mavlight, G. M. & Gutterman, J. U., 1978, In : Cancer. 41, 1, p. 70-83 14 p.

Research output: Contribution to journal › Article

Spontaneous Remission

Lymphoid Leukemia

Neoplasm Antigens

Lymphocyte Activation

Skin Tests

3 Citations (Scopus)

Acute leukemia in adults, 1977

Keating, M. J., Freireich, E. J., McCredie, K. B., Bodey, G. P., Hersh, E. M., Hester, J. P., Rodriguez, V. & Hart, J., 1977, In : CA Cancer Journal for Clinicians. 27, 1, p. 2-25 24 p.

Research output: Contribution to journal › Article

Acute Disease

Leukemia

43 Citations (Scopus)

Adjuvant chemoimmunotherapy following regional therapy for isolated recurrences of breast cancer (stage IV NED).

Buzdar, A. U., Blumenschein, G. R., Smith, T. L., Tashima, C. K., Hortobagyi, G. N., Yap, H. Y., Gutterman, J. U., Hersh, E. M. & Gehan, E. A., 1979, In : Journal of Surgical Oncology. 12, 1, p. 27-40 14 p.

Research output: Contribution to journal › Article

Mycobacterium bovis

Fluorouracil

Doxorubicin

Cyclophosphamide

Breast Neoplasms

58 Citations (Scopus)

Adjuvant chemotherapy with fluorouracil, doxorubicin, and cyclophosphamide, with or without Bacillus Calmette‐Guerin and with or without irradiation in operable breast cancer a prospective randomized trial

Buzdar, A. U., Blumenschein, G. R., Smith, T. L., Powell, K. C., Hortobagyi, G. N., Yap, H. Y., Schell, F. C., Barnes, B. C., Ames, F. C., Martin, R. G. & Hersh, E. M., 1984, In : Cancer. 53, 3, p. 384-389 6 p.

Research output: Contribution to journal › Article

Adjuvant Chemotherapy

Fluorouracil

Doxorubicin

Cyclophosphamide

Bacillus

25 Citations (Scopus)

Adjuvant immunotherapy and chemoimmunotherapy in colorectal cancer (Dukes' class C). Prolongation of disease‐free interval and survival

Mavligit, G. M., Gutterman, J. U., Malahy, M. A., Burgess, M. A., McBride, C. M., Jubert, A. & Hersh, E. M., 1977, In : Cancer. 40, 5 S, p. 2726-2730 5 p.

Research output: Contribution to journal › Article

Mycobacterium bovis

Immunotherapy

Colorectal Neoplasms

Survival

Fluorouracil

21 Citations (Scopus)

Adjuvant immunotherapy and chemoimmunotherapy in colorectal cancer of the Dukes C classification. Preliminary clinical results

Mavligit, G. M., Gutterman, J. U., Burgess, M. A., Khankhanian, N., Seibert, G. B., Speer, J. F., Reed, R. C., Jubert, A. V., Martin, R. C., McBride, C. M., Copeland, E. M., Gehan, E. A. & Hersh, E. M., 1975, In : Cancer. 36, 6 sup., p. 2421-2427 7 p.

Research output: Contribution to journal › Article

Immunotherapy

Mycobacterium bovis

Colorectal Neoplasms

Fluorouracil

Recurrence

8 Citations (Scopus)

Administration of BCG cell wall skeleton into malignant effusions: Toxic and therapeutic effects

Richman, S. P., Hersh, E. M., Gutterman, J. U., Hortobagyi, G. N., Blumenschein, G. R., Rios, A. & Ribi, E., 1981, In : Cancer Treatment Reports. 65, 5-6, p. 383-387 5 p.

Research output: Contribution to journal › Article

Cell Wall Skeleton

Poisons

Therapeutic Uses

Mycobacterium bovis

Ascitic Fluid

30 Citations (Scopus)

Advances in the biological therapy and gene therapy of malignant disease

Hersh, E. M. & Stopeck, A. T., Dec 1997, In : Clinical Cancer Research. 3, 12 II, p. 2623-2629 7 p.

Research output: Contribution to journal › Article

Biological Therapy

Genetic Therapy

Neoplasms

HLA-B7 Antigen

Immune Evasion

87 Citations (Scopus)

A four-year experience with anthracycline, cytosine arabinoside, vincristine and prednisone combination chemotherapy in 325 adults with acute leukemia

Keating, M. J., Smith, T. L., McCredie, K. B., Bodey, G. P., Hersh, E. M., Gutterman, J. U., Gehan, E. & Freireich, E. J., 1981, In : Cancer. 47, 12, p. 2779-2788 10 p.

Research output: Contribution to journal › Article

Anthracyclines

Cytarabine

Vincristine

Prednisone

Combination Drug Therapy

30 Citations (Scopus)

A human monoclonal antimelanoma single-chain Fv antibody derived from tumor-infiltrating lymphocytes

Zhang, H., Lake, D. F., Barbuto, J. A. M., Bernstein, R. M., Grimes, W. J. & Hersh, E. M., 1995, In : Cancer Research. 55, 16, p. 3584-3591 8 p.

Research output: Contribution to journal › Article

Tumor-Infiltrating Lymphocytes

Single-Chain Antibodies

B-Lymphocytes

Melanoma

Polymerase Chain Reaction

6 Citations (Scopus)

A hybridoma producing human monoclonal antibody specific for glycoprotein 120kDa of human immunodeficiency virus (HIV-1)

Lake, D., Sugano, T., Matsumoto, Y. I., Masuho, Y., Petersen, E. A., Feorino, P. & Hersh, E. M., 1989, In : Life Sciences. 45, 16

Research output: Contribution to journal › Article

Hybridomas

Viruses

HIV-1

Glycoproteins

Monoclonal Antibodies

672 Citations (Scopus)

Alpha interferon for induction of remission in hairy-cell leukemia

Quesada, J. R., Reuben, J., Manning, J. T., Hersh, E. M. & Gutterman, J. U., 1984, In : New England Journal of Medicine. 310, 1, p. 15-18 4 p.

Research output: Contribution to journal › Article

Remission Induction

Hairy Cell Leukemia

Interferon-alpha

Agranulocytosis

Thrombocytopenia

23 Citations (Scopus)

Alternating noncross-resistant combination chemotherapy and active nonspecific immunotherapy with BCG or MER-BCG for advanced breast carcinoma

Blumenschein, G. R., Hortobagyi, G. N., Richman, S. P., Gutterman, J. U., Tashima, C. K., Buzdar, A. U., Burgess, M. A., Livingston, R. B. & Hersh, E. M., 1980, In : Cancer. 45, 4, p. 742-749 8 p.

Research output: Contribution to journal › Article

methanol extraction residue (MER) tubercle bacillus fraction

Active Immunotherapy

Mycobacterium bovis

Combination Drug Therapy

Breast Neoplasms

23 Citations (Scopus)

Analysis of natural killer cell cytotoxicity of cancer patients treated with recombinant interferon

Lotzova, E., Savary, C. A., Quesada, J. R., Gutterman, J. U. & Hersh, E. M., 1983, In : Journal of the National Cancer Institute. 71, 5, p. 903-910 8 p.

Research output: Contribution to journal › Article

Natural Killer Cells

Interferons

Neoplasms

Injections

Phenotype

2 Citations (Scopus)

Analysis of the antitumor agent Bay i 7433 (copovithane) in plasma and urine by high performance liquid chromatography

Rosenblum, M. G., Hersh, E. M., Wingender, W. & Hersh, E. M., 1984, In : Journal of Liquid Chromatography. 7, 1, p. 159-166 8 p.

Research output: Contribution to journal › Article

High performance liquid chromatography

Antineoplastic Agents

High Pressure Liquid Chromatography

Urine

Plasmas

2 Citations (Scopus)

Anergy in cancer

Hersh, E. M., Gutterman, J. U. & Mavligit, G. M., 1976, In : International Journal of Dermatology. 15, 2, p. 112-120 9 p.

Research output: Contribution to journal › Article

Neoplasms

Intrinsic Factor

Neoplasm Antigens

Skin

Therapeutics

1579 Citations (Scopus)

A new type of synthetic peptide library for identifying ligand-binding activity

Lam, K. S., Salmon, S. E., Hersh, E. M., Hruby, V. J., Kazmierskit, W. M. & Knappt, R. J., Nov 7 1991, In : Nature. 354, 6348, p. 82-84 3 p.

Research output: Contribution to journal › Article

Peptide Library

Ligands

Libraries

Oligodeoxyribonucleotides

Cell Surface Receptors

29 Citations (Scopus)

An in vivo model of human multidrug-resistant multiple myeloma in SCID mice

Bellamy, W. T., Odeleye, A., Finley, P., Huizenga, B., Dalton, W. S., Weinstein, R. S., Hersh, E. M. & Grogan, T. M., Mar 1993, In : American Journal of Pathology. 142, 3, p. 691-698 8 p.

Research output: Contribution to journal › Article

SCID Mice

Multiple Myeloma

P-Glycoprotein

Heterografts

Doxorubicin

20 Citations (Scopus)

Antibodies to melanoma cell and BCG antigens in sera from tumour-free individuals and from melanoma patients

Minden, P., Jarrett, C., Mcclatchy, J. K., Gutterman, J. U. & Hersh, E. M., 1976, In : Nature. 263, 5580, p. 774-777 4 p.

Research output: Contribution to journal › Article

Mycobacterium bovis

Melanoma

Antigens

Antibodies

Mycobacterium

85 Citations (Scopus)

Antibodies to the primary immunodominant domain of human immunodeficiency virus type 1 (HIV-1) glycoprotein gp41 enhance HIV-1 infection in vitro

Robinson, W. E., Kawamura, T., Lake, D., Masuho, Y., Mitchell, W. M. & Hersh, E. M., 1990, In : Journal of Virology. 64, 11, p. 5301-5305 5 p.

Research output: Contribution to journal › Article

Immunodominant Epitopes

Virus Diseases

Human immunodeficiency virus 1

HIV-1

glycoproteins

8 Citations (Scopus)

Antibodies to tumor necrosis factor: a component of B cell immune responses with a role in tumor/host interaction

Barbuto, J. A. M., Grimes, W. J. & Hersh, E. M., Jan 1995, In : Cancer Immunology, Immunotherapy. 40, 1, p. 31-36 6 p.

Research output: Contribution to journal › Article

B-Lymphocytes

Tumor Necrosis Factor-alpha

Antibodies

Neoplasms

Antibody Formation

22 Citations (Scopus)

Antibody-dependent cell-mediated cytotoxicity in human cancer. Characterization of patient leukocyte activity and treatment effects

Hersh, E. M., Murphy, S. G., Gutterman, J. U., Morgan, J., Quesada, J., Zander, A. & Stewart, D., 1982, In : Cancer. 49, 2, p. 251-260 10 p.

Research output: Contribution to journal › Article

Antibody-Dependent Cell Cytotoxicity

Leukocytes

Neoplasms

Therapeutics

Erythrocytes

28 Citations (Scopus)

Antibody development to viral and allogeneic tumor cell-associated antigens in patients with malignant melanoma and ovarian carcinoma treated with lysates of virus-infected tumor cells

Savage, H. E., Rossen, R. D., Hersh, E. M., Freedman, R. S., Bowen, J. M. & Plager, C., 1986, In : Cancer Research. 46, 4 II, p. 2127-2133 7 p.

Research output: Contribution to journal › Article

Oncogenic Viruses

Melanoma

Carcinoma

Antigens

Viruses

9 Citations (Scopus)

Antibody responses of remission leukemia patients receiving active specific and nonspecific immunotherapy

Granatek, C. H., Ezaki, K., Hersh, E. M., Keating, M. J. & Rasmussen, S., 1981, In : Cancer. 47, 2, p. 272-279 8 p.

Research output: Contribution to journal › Article

Immunotherapy

Antibody Formation

Leukemia

Mycobacterium bovis

Antigens

26 Citations (Scopus)

Antigen dose in the human immune response. Dose-response relationships in the human immune response to Keyhole limpet hemocyanin

Curtis, J. E., Hersh, E. M., Butler, W. T. & Rossen, R. D., 1971, In : The Journal of Laboratory and Clinical Medicine. 78, 1, p. 61-69 9 p.

Research output: Contribution to journal › Article

Antigens

Immunization

Lymphocytes

Hemagglutinins

Skin

103 Citations (Scopus)

Antigen-driven oligoclonal expansion of tumor-infiltrating B cells in infiltrating ductal carcinoma of the breast

Coronella, J. A., Perry, C. S., Welch, M., Trevor, K. T., Stopeck, A. T., Villar, H. & Hersh, E. M., Aug 15 2002, In : Journal of Immunology. 169, 4, p. 1829-1836 8 p.

Research output: Contribution to journal › Article

Carcinoma, Ductal, Breast

B-Lymphocytes

Antigens

Neoplasms

Ductal Carcinoma

8 Citations (Scopus)

Antigen expression and cell surface properties of human leukemic blasts

Cotropia, J. P., Gutterman, J. U. & Hersh, E. M., 1976, In : Annals of the New York Academy of Sciences. Vol. 276, p. 146-164 19 p.

Research output: Contribution to journal › Article

Surface Properties

Surface properties

Immunoglobulin G

Immunoglobulin Fab Fragments

Antigens

49 Citations (Scopus)

Antigen solubilized from human leukemia: Lymphocyte stimulation

Gutterman, J. U., Mavligit, G., McCredie, K. B., Bodey, G. P., Freireich, E. J. & Hersh, E. M., 1972, In : Science. 177, 4054, p. 1114-1115 2 p.

Research output: Contribution to journal › Article

Lymphocyte Activation

Leukemia

Lymphocytes

Antigens

Tissue Donors

9 Citations (Scopus)

Antigen-specific immunity in recipients of leukocyte transfusions from immune donors.

Curtis, J. E., Hersh, E. M. & Freireich, E. J., Dec 1970, In : Cancer Research. 30, 12, p. 2921-2929 9 p.

Research output: Contribution to journal › Article

Maternally Acquired Immunity

Leukocyte Transfusion

Hemagglutination Tests

Antibody Specificity

Lymphocyte Activation

33 Citations (Scopus)

Antiproliferative and antitumor activity of the 2-cyanoaziridine compound imexon on tumor cell lines and fresh tumor cells in vitro

Hersh, E. M., Gschwind, C. R., Taylor, C. W., Dorr, R. T., Taetle, R. & Salmon, S. E., Aug 19 1992, In : Journal of the National Cancer Institute. 84, 16, p. 1238-1244 7 p.

Research output: Contribution to journal › Article

Tumor Cell Line

Tumors

Tumor

Cells

Line

42 Citations (Scopus)

Anti-tumor antibody produced by human tumor-infiltrating and peripheral blood B lymphocytes

Punt, C. J. A., Barbuto, J. A. M., Zhang, H., Grimes, W. J., Hatch, K. D. & Hersh, E. M., Jul 1994, In : Cancer Immunology, Immunotherapy. 38, 4, p. 225-232 8 p.

Research output: Contribution to journal › Article

Neoplasm Antibodies

Anti-Idiotypic Antibodies

B-Lymphocytes

Neoplasms

Feeder Cells

16 Citations (Scopus)

A phase 1-2 study of imexon plus dacarbazine in patients with unresectable metastatic melanoma

Weber, J. S., Samlowski, W. E., Gonzalez, R., Ribas, A., Stephenson, J., O'Day, S., Sato, T., Dorr, R. T., Grenier, K. & Hersh, E. M., Aug 1 2010, In : Cancer. 116, 15, p. 3683-3691 9 p.

Research output: Contribution to journal › Article

Dacarbazine

Melanoma

Maximum Tolerated Dose

Pharmacokinetics

Survival

85 Citations (Scopus)

A phase 2 clinical trial of nab-Paclitaxel in previously treated and chemotherapy-naive patients with metastatic melanoma

Hersh, E. M., O'Day, S. J., Ribas, A., Samlowski, W. E., Gordon, M. S., Shechter, D. E., Clawson, A. A. & Gonzalez, R., Jan 1 2010, In : Cancer. 116, 1, p. 155-163 9 p.

Research output: Contribution to journal › Article

Melanoma

Clinical Trials

Drug Therapy

Survival

Albumin-Bound Paclitaxel

2 Citations (Scopus)

A Phase 2 Randomized, Double-Blind, Multicenter Trial of Imexon Plus Gemcitabine Versus Gemcitabine Plus Placebo in Patients With Metastatic Chemotherapy-naïve Pancreatic Adenocarcinoma

Cohen, S. J., Zalupski, M. M., Conkling, P., Nugent, F., Ma, W. W., Modiano, M., Pascual, R., Lee, F. C., Wong, L. & Hersh, E. M., Dec 24 2015, (Accepted/In press) In : American Journal of Clinical Oncology: Cancer Clinical Trials.

Research output: Contribution to journal › Article

gemcitabine

Multicenter Studies

Adenocarcinoma

Placebos

Drug Therapy

37 Citations (Scopus)

A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors

Taylor, C. W., Dorr, R. T., Fanta, P., Hersh, E. M. & Salmon, S. E., 2001, In : Cancer Chemotherapy and Pharmacology. 47, 1, p. 83-88 6 p.

Research output: Contribution to journal › Article

Pharmacodynamics

Asparaginase

Tumors

Asparagine

Neoplasms

208 Citations (Scopus)

A phase II multicenter study of ipilimumab with or without dacarbazine in chemotherapy-naïve patients with advanced melanoma

Hersh, E. M., O'Day, S. J., Powderly, J., Khan, K. D., Pavlick, A. C., Cranmer, L. D., Samlowski, W. E., Nichol, G. M., Yellin, M. J. & Weber, J. S., Jun 2011, In : Investigational New Drugs. 29, 3, p. 489-498 10 p.

Research output: Contribution to journal › Article

Dacarbazine

Multicenter Studies

Melanoma

Drug Therapy

ipilimumab

31 Citations (Scopus)

A phase II trial of recombinant tumor necrosis factor in patients with adenocarcinoma of the pancreas: A southwest oncology group study

Brown, T. D., Goodman, P., Fleming, T., Macdonald, J. S., Hersh, E. M. & Braun, T. J., 1991, In : Journal of Immunotherapy. 10, 5, p. 376-378 3 p.

Research output: Contribution to journal › Article

Pancreas

Adenocarcinoma

Tumor Necrosis Factor-alpha

Hypertriglyceridemia

Anorexia

21 Citations (Scopus)

A phase II trial of recombinant tumor necrosis factor in patients with metastatic colorectal adenocarcinoma: A Southwest Oncology Group Study

Whitehead, R. P., Fleming, T., Macdonald, J. S., Goodman, P. J., Neefe, J., Braun, T. J., Swinnen, L. J. & Hersh, E. M., 1990, In : Journal of Biological Response Modifiers. 9, 6, p. 588-591 4 p.

Research output: Contribution to journal › Article

Adenocarcinoma

Tumor Necrosis Factor-alpha

Nausea

Vomiting

Subclavian Vein

18 Citations (Scopus)

A Phase II Trial of Vinorelbine Tartrate in Patients with Disseminated Malignant Melanoma and One Prior Systemic Therapy: A Southwest Oncology Group Study

Whitehead, R. P., Moon, J., McCachren, S. S., Hersh, E. M., Samlowski, W. E., Beck, J. T., Tchekmedyian, N. S. & Sondak, V. K., Apr 15 2004, In : Cancer. 100, 8, p. 1699-1704 6 p.

Research output: Contribution to journal › Article

Melanoma

Therapeutics

Confidence Intervals

vinorelbine

Disease-Free Survival

18 Citations (Scopus)

A phase i study of imexon plus gemcitabine as first-line therapy for advanced pancreatic cancer

Cohen, S. J., Zalupski, M. M., Modiano, M. R., Conkling, P., Patt, Y. Z., Davis, P., Dorr, R. T., Boytim, M. L. & Hersh, E. M., Jul 2010, In : Cancer Chemotherapy and Pharmacology. 66, 2, p. 287-294 8 p.

Research output: Contribution to journal › Article

gemcitabine

Pancreatic Neoplasms

Toxicity

Maximum Tolerated Dose

Abdominal Pain

5 Citations (Scopus)

A phase I study of intravenous azimexon therapy in human cancer

Patt, Y. Z., Hersh, E. M., Reuben, J., Claghorn, L. & Mavligit, G., 1986, In : Journal of Biological Response Modifiers. 5, 4, p. 313-318 6 p.

Research output: Contribution to journal › Article

Azirines

Aziridines

Immunologic Adjuvants

Drug Evaluation

Lymphocyte Activation

38 Citations (Scopus)

A phase I study of the dolastatin-15 analogue tasidotin (ILX651) administered intravenously daily for 5 consecutive days every 3 weeks in patients with advanced solid tumors

Ebbinghaus, S., Rubin, E., Hersh, E. M., Cranmer, L. D., Bonate, P. L., Fram, R. J., Jekunen, A., Weitman, S. & Hammond, L. A., Nov 1 2005, In : Clinical Cancer Research. 11, 21, p. 7807-7816 10 p.

Research output: Contribution to journal › Article

Maximum Tolerated Dose

Neoplasms

Neutropenia

Fatigue

Melanoma

18 Citations (Scopus)

A phase I study of therapy with recombinant granulocyte-macrophage colony-stimulating factor administered by IV bolus or continuous infusion.

Rifkin, R. M., Hersh, E. M. & Salmon, S. E., Aug 1988, In : Behring Institute Mitteilungen. 83, p. 125-133 9 p.

Research output: Contribution to journal › Article

Granulocyte-Macrophage Colony-Stimulating Factor

Bone

Granulocytes

Eructation

Bone Marrow