Evan M Hersh

  • 19310 Citations
  • 67 h-Index
1965 …2018

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Ability of cell-sized beads bearing tumor cell membrane proteins to stimulate LAK cells to secrete interferon-γ and tumor necrosis factor-α1

Chong, A. S. F., Pinkard, J. K., Lam, K. S., Scuderi, P., Hersh, E. M. & Grimes, W. J., Apr 15 1991, In : Cellular Immunology. 134, 1, p. 96-110 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Abnormal lymphocyte response to exogenous interleukin-2 in homosexuals with acquired immune deficiency syndrome (AIDS) and AIDS related complex (ARC)

Murray, J. L., Hersh, E. M., Reuben, J. M., Munn, C. G. & Mansell, P. W., 1985, In : Clinical and Experimental Immunology. 60, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Acquired immune deficiency syndrome: A new clinical entity

Hersh, E. M. & Mansell, P. W. A., Apr 1983, In : Clinical Immunology Newsletter. 4, 4, p. 39-43 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Actinomycin‐D plus 5‐(3,3‐dimethyl‐ 1‐triazeno)‐ imidazole‐4‐carboxamine (DTIC) with or without intravenous corynebacterium parvum in metastatic malignant melanoma

Robidoux, A., Gutterman, J. U., Bodey, G. P. & Hersh, E. M., Jun 1 1982, In : Cancer. 49, 11, p. 2246-2251 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Activation of Cyclic Nucleotide Phosphodiesterase from Isolated Human Peripheral Blood Lymphocytes by Mitogenic Agents

Epstein, P. M., Mills, J. S., Hersh, E. M., Strada, S. J. & Thompson, W. J., Feb 1 1980, In : Cancer Research. 40, 2, p. 379-386 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Activation of human lymphocyte high affinity cyclic AMP phosphodiesterase by culture with 1-methyl-3-isobutylxanthine

Thompson, W. J., Ross, C. P., Hersh, E. M., Epstein, P. M. & Strada, S. J., Jun 13 1980, In : Journal of Cyclic Nucleotide Research. 6, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

ACTIVE IMMUNOTHERAPY WITH B.C.G. FOR RECURRENT MALIGNANT MELANOMA

Gutterman, J. U., McBride, C., Freireich, E. J., Mavligit, G., Frei, E. & Hersh, E. M., Jun 2 1973, In : The Lancet. 301, 7814, p. 1208-1212 5 p.

Research output: Contribution to journalArticle

188 Scopus citations

Active specific immunization in malignant melanoma

Gercovich, F. G., Gutterman, J. U., Maviigit, G. M. & Hersh, E. M., 1975, In : Medical and Pediatric Oncology. 1, 3, p. 277-287 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Active specific immunization with allogeneic leukemia associated antigens or irradiated allogeneic leukemia cells in acute leukemia

Ezaki, K., Hersh, E. M., Keating, M., Hollinshead, S. D. A., McCredie, K. B., Mavlight, G. M. & Gutterman, J. U., Jan 1978, In : Cancer. 41, 1, p. 70-83 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Acute leukemia in adults, 1977

Keating, M. J., Freireich, E. J., McCredie, K. B., Bodey, G. P., Hersh, E., Hester, J. P., Rodriguez, V. & Hart, J., Jan 1 1977, In : CA: A Cancer Journal for Clinicians. 27, 1, p. 2-25 24 p.

Research output: Contribution to journalArticle

3 Scopus citations

Adjuvant chemoimmunotherapy following regional therapy for isolated recurrences of breast cancer (stage IV NED)

Buzdar, A. U., Blumenschein, G. R., Smith, T. L., Tashima, C. K., Hortobagyi, G. N., Yap, H. Y., Gutterman, J. U., Hersh, E. M. & Gehan, E. A., 1979, In : Journal of Surgical Oncology. 12, 1, p. 27-40 14 p.

Research output: Contribution to journalArticle

43 Scopus citations

Adjuvant chemotherapy with fluorouracil, doxorubicin, and cyclophosphamide, with or without Bacillus Calmette‐Guerin and with or without irradiation in operable breast cancer a prospective randomized trial

Buzdar, A. U., Blumenschein, G. R., Smith, T. L., Powell, K. C., Hortobagyi, G. N., Yap, H. Y., Schell, F. C., Barnes, B. C., Ames, F. C., Martin, R. G. & Hersh, E. M., Feb 1 1984, In : Cancer. 53, 3, p. 384-389 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Adjuvant immunotherapy and chemoimmunotherapy in colorectal cancer (Dukes' class C). Prolongation of disease‐free interval and survival

Mavligit, G. M., Gutterman, J. U., Malahy, M. A., Burgess, M. A., McBride, C. M., Jubert, A. & Hersh, E. M., Nov 1977, In : Cancer. 40, 5 S, p. 2726-2730 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Adjuvant immunotherapy and chemoimmunotherapy in colorectal cancer of the Dukes' C classification. Preliminary clinical results

Mavligit, G. M., Gutterman, J. U., Burgess, M. A., Khankhanian, N., Seibert, G. B., Speer, J. F., Reed, R. C., Jubert, A. V., Martin, R. C., McBride, C. M., Copeland, E. M., Gehan, E. A. & Hersh, E. M., Dec 1975, In : Cancer. 36, 6 S, p. 2421-2427 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Administration of BCG cell wall skeleton into malignant effusions: Toxic and therapeutic effects

Richman, S. P., Hersh, E. M., Gutterman, J. U., Hortobagyi, G. N., Blumenschein, G. R., Rios, A. & Ribi, E., Aug 29 1981, In : Cancer Treatment Reports. 65, 5-6, p. 383-387 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Advances in the biological therapy and gene therapy of malignant disease

Hersh, E. M. & Stopeck, A. T., Dec 1 1997, In : Clinical Cancer Research. 3, 12 II, p. 2623-2629 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

A four‐year experience with anthracycline, cytosine arabinoside, vincristine and prednisone combination chemotherapy in 325 adults with acute leukemia

Keating, M. J., Smith, T. L., McCredie, K. B., Bodey, G. P., Hersh, E. M., Gutterman, J. U., Gehan, E. & Freireich, E. J., Jun 15 1981, In : Cancer. 47, 12, p. 2779-2788 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

A Human Monoclonal Antimelanoma Single-Chain Fv Antibody Derived from Tumor-infiltrating Lymphocytes

Zhang, H., Lake, D. F., Barbuto, J. A. M., Bernstein, R. M., Grimes, W. J. & Hersh, E. M., Aug 1 1995, In : Cancer Research. 55, 16, p. 3584-3591 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

A hybridoma producing human monoclonal antibody specific for glycoprotein 120kDa of human immunodeficiency virus (HIV-1)

Lake, D., Sugano, T., Matsumoto, Y. I., Masuho, Y., Petersen, E. A., Feorino, P. & M. Hersh, E., 1989, In : Life Sciences. 45, 16, p. iii-x

Research output: Contribution to journalArticle

6 Scopus citations

Alpha Interferon for Induction of Remission in Hairy-Cell Leukemia

Quesada, J. R., Reuben, J., Manning, J. T., Hersh, E. M. & Gutterman, J. U., Jan 5 1984, In : New England Journal of Medicine. 310, 1, p. 15-18 4 p.

Research output: Contribution to journalArticle

678 Scopus citations

Alternating noncross‐resistant combination chemotherapy and active nonspecific immunotherapy with BCG or MER‐BCG for advanced breast carcinoma

Blumenschein, G. R., Hortobagyi, G. N., Richman, S. P., Gutterman, J. U., Tashima, C. K., Buzdar, A. U., Burgess, M. A., Livingston, R. B. & Hersh, E. M., Feb 15 1980, In : Cancer. 45, 4, p. 742-749 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Analysis of natural killer cell cytotoxicity of cancer patients treated with recombinant interferon

Lotzova, E., Savary, C. A., Quesada, J. R., Gutterman, J. U. & Hersh, E. M., Dec 1 1983, In : Journal of the National Cancer Institute. 71, 5, p. 903-910 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Analysis of the Antitumor Agent Bay i 7433 (Copovithane) in Plasma and Urine by High Performance Liquid Chromatography

Rosenblum, M. G., Hersh, E. M. & Wingender, W., Jan 1 1984, In : Journal of Liquid Chromatography. 7, 1, p. 159-166 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

An effective new chemoimmunotherapy regimen for disseminated malignant melanoma (DMM)

Gutterman, J., Hersh, E. & Benjamin, R., Jan 1 1977, In : Proceedings of the American Association for Cancer Research. vol. 18, p. No. C-135

Research output: Contribution to journalArticle

2 Scopus citations

A new type of synthetic peptide library for identifying ligand-binding activity

Lam, K. S., Salmon, S. E., Hersh, E. M., Hruby, V. J., Kazmierskit, W. M. & Knappt, R. J., Nov 7 1991, In : Nature. 354, 6348, p. 82-84 3 p.

Research output: Contribution to journalArticle

1597 Scopus citations

An in vivo model of human multidrug-resistant multiple myeloma in SCID mice

Bellamy, W. T., Odeleye, A., Finley, P., Huizenga, B., Dalton, W. S., Weinstein, R. S., Hersh, E. M. & Grogan, T. M., Dec 1 1993, In : American Journal of Pathology. 142, 3, p. 691-698 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Antibodies to melanoma cell and BCG antigens in sera from tumour-free individuals and from melanoma patients

Minden, P., Jarrett, C., Mcclatchy, J. K., Gutterman, J. U. & Hersh, E. M., Dec 1 1976, In : Nature. 263, 5580, p. 774-777 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Antibodies to the primary immunodominant domain of human immunodeficiency virus type 1 (HIV-1) glycoprotein gp41 enhance HIV-1 infection in vitro

Robinson, W. E., Kawamura, T., Lake, D., Masuho, Y., Mitchell, W. M. & Hersh, E. M., Jan 1 1990, In : Journal of virology. 64, 11, p. 5301-5305 5 p.

Research output: Contribution to journalArticle

86 Scopus citations

Antibodies to tumor necrosis factor: a component of B cell immune responses with a role in tumor/host interaction

Barbuto, J. A. M., Grimes, W. J. & Hersh, E. M., Jan 1 1995, In : Cancer Immunology Immunotherapy. 40, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Antibody‐dependent cell‐mediated cytotoxicity in human cancer: Characterization of patient leukocyte activity and treatment effects

Hersh, E. M., Murphy, S. G., Gutterman, J. U., Morgan, J., Quesada, J., Zander, A. & Stewart, D., Jan 15 1982, In : Cancer. 49, 2, p. 251-260 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Antibody development to viral and allogeneic tumor cell-associated antigens in patients with malignant melanoma and ovarian carcinoma treated with lysates of virus-infected tumor cells

Savage, H. E., Rossen, R. D., Hersh, E. M., Freedman, R. S., Bowen, J. M. & Plager, C., Apr 1 1986, In : Cancer Research. 46, p. 2127-2133 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Antibody responses of leukemia patients in remission who receive active specific immunotherapy

Granatek, C., Ezaki, K. & Hersh, E., 1979, In : Proceedings of the American Association for Cancer Research. Vol. 20, p. No. 684

Research output: Contribution to journalArticle

Antibody responses of remission leukemia patients receiving active specific and nonspecific immunotherapy

Granatek, C. H., Ezaki, K., Hersh, E. M., Keating, M. J. & Rasmussen, S., Jan 15 1981, In : Cancer. 47, 2, p. 272-279 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Antigen dose in the human immune response. Dose-response relationships in the human immune response to Keyhole limpet hemocyanin

Curtis, J. E., Hersh, E. M., Butler, W. T. & Rossen, R. D., Jul 1971, In : The Journal of Laboratory and Clinical Medicine. 78, 1, p. 61-69 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Antigen-driven oligoclonal expansion of tumor-infiltrating B cells in infiltrating ductal carcinoma of the breast

Coronella, J. A., Spier, C., Welch, M., Trevor, K. T., Stopeck, A. T., Villar, H. & Hersh, E. M., Aug 15 2002, In : Journal of Immunology. 169, 4, p. 1829-1836 8 p.

Research output: Contribution to journalArticle

Open Access
108 Scopus citations

ANTIGEN EXPRESSION AND CELL SURFACE PROPERTIES OF HUMAN LEUKEMIC BLASTS

Cotropia, J. P., Gutterman, J. U., Hersh, E. M., Granatek, C. H. & Mavligit, G. M., Sep 1976, In : Annals of the New York Academy of Sciences. 276, 1, p. 146-164 19 p.

Research output: Contribution to journalArticle

8 Scopus citations

Antigen solubilized from human leukemia: Lymphocyte stimulation

Gutterman, J. U., Mavligit, G., McCredie, K. B., Bodey, G. P., Freireich, E. J. & Hersh, E. M., Jan 1 1972, In : Science. 177, 4054, p. 1114-1115 2 p.

Research output: Contribution to journalArticle

49 Scopus citations

Antigen-specific Immunity in Recipients of Leukocyte Transfusions from Immune Donors

Curtis, J. E., Hersh, E. M. & Freireich, E. J., Dec 1970, In : Cancer Research. 30, 12, p. 2921-2929 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Antiproliferative and antitumor activity of the 2-cyanoaziridine compound imexon on tumor cell lines and fresh tumor cells in vitro

Hersh, E. M., Gschwind, C. R., Taylor, C. W., Dorr, R. T., Taetle, R. & Salmon, S. E., Aug 19 1992, In : Journal of the National Cancer Institute. 84, 16, p. 1238-1244 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Anti-tumor antibody produced by human tumor-infiltrating and peripheral blood B lymphocytes

Punt, C. J. A., Barbuto, J. A. M., Zhang, H., Grimes, W. J., Hatch, K. D. & Hersh, E. M., Jul 1 1994, In : Cancer Immunology Immunotherapy. 38, 4, p. 225-232 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

A phase 1-2 study of imexon plus dacarbazine in patients with unresectable metastatic melanoma

Weber, J. S., Samlowski, W. E., Gonzalez, R., Ribas, A., Stephenson, J., O'Day, S., Sato, T., Dorr, R., Grenier, K. & Hersh, E., Aug 1 2010, In : Cancer. 116, 15, p. 3683-3691 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

A phase 2 clinical trial of nab-Paclitaxel in previously treated and chemotherapy-naive patients with metastatic melanoma

Hersh, E. M., O'Day, S. J., Ribas, A., Samlowski, W. E., Gordon, M. S., Shechter, D. E., Clawson, A. A. & Gonzalez, R., Jan 1 2010, In : Cancer. 116, 1, p. 155-163 9 p.

Research output: Contribution to journalArticle

93 Scopus citations

A Phase 2 Randomized, Double-Blind, Multicenter Trial of Imexon Plus Gemcitabine Versus Gemcitabine Plus Placebo in Patients with Metastatic Chemotherapy-naïve Pancreatic Adenocarcinoma

Cohen, S. J., Zalupski, M. M., Conkling, P., Nugent, F., Ma, W. W., Modiano, M., Pascual, R., Lee, F. C., Wong, L. & Hersh, E., Jan 1 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 3, p. 230-235 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors

Taylor, C. W., Dorr, R. T., Fanta, P., Hersh, E. M. & Salmon, S. E., Jul 31 2001, In : Cancer Chemotherapy And Pharmacology. 47, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

A phase II multicenter study of ipilimumab with or without dacarbazine in chemotherapy-naïve patients with advanced melanoma

Hersh, E. M., O'Day, S. J., Powderly, J., Khan, K. D., Pavlick, A. C., Cranmer, L. D., Samlowski, W. E., Nichol, G. M., Yellin, M. J. & Weber, J. S., Jun 1 2011, In : Investigational New Drugs. 29, 3, p. 489-498 10 p.

Research output: Contribution to journalArticle

216 Scopus citations

A phase II trial of recombinant tumor necrosis factor in patients with adenocarcinoma of the pancreas: A southwest oncology group study

Brown, T. D., Goodman, P., Fleming, T., Macdonald, J. S., Hersh, E. M. & Braun, T. J., Oct 1991, In : Journal of Immunotherapy. 10, 5, p. 376-378 3 p.

Research output: Contribution to journalArticle

31 Scopus citations

A phase II trial of recombinant tumor necrosis factor in patients with metastatic colorectal adenocarcinoma: A southwest oncology group study

Whitehead, R. P., Fleming, T., Macdonald, J. S., Goodman, P. J., Neefe, J., Braun, T. J., Swinnen, L. J. & Hersh, E. M., Dec 1990, In : Journal of Biological Response Modifiers. 9, 6, p. 588-591 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

A Phase II Trial of Vinorelbine Tartrate in Patients with Disseminated Malignant Melanoma and One Prior Systemic Therapy: A Southwest Oncology Group Study

Whitehead, R. P., Moon, J., McCachren, S. S., Hersh, E. M., Samlowski, W. E., Beck, J. T., Tchekmedyian, N. S. & Sondak, V. K., Apr 15 2004, In : Cancer. 100, 8, p. 1699-1704 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

A phase i study of imexon plus gemcitabine as first-line therapy for advanced pancreatic cancer

Cohen, S. J., Zalupski, M. M., Modiano, M. R., Conkling, P., Patt, Y. Z., Davis, P., Dorr, R. T., Boytim, M. L. & Hersh, E. M., Jul 1 2010, In : Cancer Chemotherapy And Pharmacology. 66, 2, p. 287-294 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

A phase I study of intravenous azimexon therapy in human cancer

Patt, Y. Z., Hersh, E. M., Reuben, J., Claghorn, L. & Mavligit, G., Aug 1986, In : Journal of Biological Response Modifiers. 5, 4, p. 313-318 6 p.

Research output: Contribution to journalArticle

5 Scopus citations