Evan M Hersh

  • 18991 Citations
  • 67 h-Index
1965 …2021

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1991

Phase II studies of recombinant human tumor necrosis factor alpha in patients with malignant disease: A summary of the southwest oncology group experience

Hersh, E. M., Metch, B. S., Muggia, F. M., Brown, T. D., Whitehead, R. P., Budd, G. T., Rinehart, J. J., Crawford, E. D., Bonnet, J. D. & Behrens, B. C., Dec 1991, In : Journal of Immunotherapy. 10, 6, p. 426-431 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Phase II study of intravenous bolus recombinant interleukin-2 in advanced malignant melanoma: Southwest oncology group study

Whitehead, R. P., Kopecky, K. J., Samson, M. K., Constanzi, J. J., Natale, R. B., Feun, L. G., Hersh, E. M. & Rinehart, J. J., Sep 4 1991, In : Journal of the National Cancer Institute. 83, 17, p. 1250-1252 3 p.

Research output: Contribution to journalArticle

39 Scopus citations

Recognition of human immunodeficiency virus glycoproteins by natural anti-carbohydrate antibodies in human serum

Tomiyama, T., Lake, D., Masuho, Y. & Hersh, E. M., May 31 1991, In : Biochemical and Biophysical Research Communications. 177, 1, p. 279-285 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
1990

Antibodies to the primary immunodominant domain of human immunodeficiency virus type 1 (HIV-1) glycoprotein gp41 enhance HIV-1 infection in vitro

Robinson, W. E., Kawamura, T., Lake, D., Masuho, Y., Mitchell, W. M. & Hersh, E. M., Jan 1 1990, In : Journal of virology. 64, 11, p. 5301-5305 5 p.

Research output: Contribution to journalArticle

85 Scopus citations

A phase II trial of recombinant tumor necrosis factor in patients with metastatic colorectal adenocarcinoma: A southwest oncology group study

Whitehead, R. P., Fleming, T., Macdonald, J. S., Goodman, P. J., Neefe, J., Braun, T. J., Swinnen, L. J. & Hersh, E. M., Dec 1990, In : Journal of Biological Response Modifiers. 9, 6, p. 588-591 4 p.

Research output: Contribution to journalArticle

21 Scopus citations
5 Scopus citations

Diethyldithiocarbamate, a novel immunomodulator, prolongs survival in autoimmune MRL- lpr lpr mice

Halpern, M. D., Hersh, E. & Yocum, D. E., May 1990, In : Clinical Immunology and Immunopathology. 55, 2, p. 242-254 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Human monoclonal antibodies to the human immunodeficiency virus type 1 (HIV-1) transmembrane glycoprotein gp41 enhance HIV-1 infection in vitro

Robinson, W. E., Kawamura, T., Gorny, M. K., Lake, D., Xu, J. Y., Matsumoto, Y., Sugano, T., Masuho, Y., Mitchell, W. M., Hersh, E. & Zolla-Pazner, S., Apr 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 8, p. 3185-3189 5 p.

Research output: Contribution to journalArticle

Open Access
75 Scopus citations

Isolation and characterization of a human monoclonal antibody which reacts with breast and colorectal carcinoma

Goldstein, N. I., Nagle, R., Villar, H., Hersh, E. & Fisher, P. B., Dec 1 1990, In : Anticancer research. 10, 6, p. 1491-1500 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Pharmacokinetics of Recombinant Interleukin 2 in Humans

Konrad, M. W., Hemstreet, G., Hersh, E. M., Mansell, P. W. A., Mertelsmann, R., Kolitz, J. E. & Bradley, E. C., Apr 15 1990, In : Cancer Research. 50, 7, p. 2009-2017 9 p.

Research output: Contribution to journalArticle

169 Scopus citations

Phenotypic analyses of lymphokine-activated killer cells that release interferon γ and tumor necrosis factor α

Chong, A. S. F., Ybarrondo, B., Grimes, W. J., Hersh, E. M. & Scuderi, P., Jul 1 1990, In : Cancer Immunology Immunotherapy. 31, 4, p. 255-259 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
1989

A hybridoma producing human monoclonal antibody specific for glycoprotein 120kDa of human immunodeficiency virus (HIV-1)

Lake, D., Sugano, T., Matsumoto, Y. I., Masuho, Y., Petersen, E. A., Feorino, P. & M. Hersh, E., 1989, In : Life Sciences. 45, 16, p. iii-x

Research output: Contribution to journalArticle

6 Scopus citations

A phase I trial of recombinant tumor necrosis factor (rTNF) administered by continuous intravenous infusion in patients with disseminated malignancy

Schwartz, J. E., Scuderi, P., Wiggins, C., Rudolph, A. & Hersh, E. M., Sep 1 1989, In : Biotherapy. 1, 3, p. 207-214 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

A pilot study of diethyldithiocarbamate in patients with acquired immune deficiency syndrome (AIDS) and the AIDS-related complex

Brewton, G. W., Hersh, E. M., Rios, A., Mansell, P. W. A., Hollinger, B. & Reuben, J. M., 1989, In : Life Sciences. 45, 26, p. 2509-2520 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

A randomized, controlled dose response study of intravenous sodium diethyldithiocarbamate in patients with advanced human immunodeficiency virus infection

Kaplan, C. S., Petersen, E. A., Yocum, D. & Hersh, E. M., 1989, In : Life Sciences. 45, 22, p. iii-ix

Research output: Contribution to journalArticle

14 Scopus citations

Colony-stimulating factors. Clinical potential

Rifkin, R. M. & Hersh, E. M., Jan 1 1989, In : Hospital Therapy. 14, 8, p. 44-54 11 p.

Research output: Contribution to journalArticle

Cytostatic and cytotoxic activity of lymphokine-activated killer cell supernatants

Hersh, E. M., Scuderi, P., Grimes, W. J., Chong, A., Brailey, J. L., Gschwind, C. R. & Salmon, S. E., Jan 1 1989, In : Cancer Immunology Immunotherapy. 30, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Increased peripheral blood leukocyte cytotoxic activity in cancer patients during the continuous intravenous administration of recombinant human tumor necrosis factor

Charnetsky, P. S., Greisman, R. A., Salmon, S. E., Hersh, E. M. & Scuderi, P., Jan 1 1989, In : Journal of Clinical Immunology. 9, 1, p. 34-38 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Phase I study of cancer therapy with recombinant interleukin-2 administered by intravenous bolus injection

Hersh, E. M., Lee Murray, J., Ki Hong, W., Rosenblum, M. G., Reuben, J. M., Weilbaecher, R., Sarwal, A. N., Bradley, E. C., Konrad, M. & Arnett, F. C., Sep 1 1989, In : Biotherapy. 1, 3, p. 215-226 12 p.

Research output: Contribution to journalArticle

12 Scopus citations
23 Scopus citations

Tumor targets stimulate IL-2 activated killer cells to produce interferon-γ and tumor necrosis factor

Chong, A. S. F., Scuderi, P., Grimes, W. J. & Hersh, E. M., Jan 1 1989, In : Journal of Immunology. 142, 6, p. 2133-2139 7 p.

Research output: Contribution to journalArticle

76 Scopus citations
1988
18 Scopus citations

Blocking of lymphokine activated killer (LAK) cell mediated cytotoxicity by cell-sized beads bearing tumor cell proteins

Chong, A. S. F., Hersh, E. M. & Grimes, W. J., Dec 1 1988, In : Journal of Immunology. 141, 12, p. 4418-4424 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Human monoclonal antibody against glycoproteins of human immunodeficiency virus

Sugano, T., Masuho, Y., Matsumoto, Y. I., Lake, D., Gschwind, C., Petersen, E. A. & Hersh, E. M., Sep 30 1988, In : Biochemical and Biophysical Research Communications. 155, 3, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Multiple agent chemotherapy (POACH) in previously treated and untreated patients with chronic lymphocytic leukemia

Keating, M. J., Scouros, M., Murphy, S., Kantarjian, H., Hester, J., McCredie, K. B., Hersh, E. M. & Freireich, E. J., Jan 1 1988, In : Leukemia. 2, 3, p. 157-164 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

Prospective randomized trial of high-dose cisplatin and fluorouracil infusion with or without sodium diethyldithiocarbamate in recurrent and/or metastatic squamous cell carcinoma of the head and neck

Paredes, J., Hong, W. K., Felder, T. B., Dimery, I. W., Choksi, A. J., Newman, R. A., Castellanos, A. M., Robbins, K. T., McCarthy, K., Atkinson, N., Kramer, A. M., Hersh, E. M. & Goepfert, H., Jan 1 1988, In : Journal of Clinical Oncology. 6, 6, p. 955-962 8 p.

Research output: Contribution to journalArticle

41 Scopus citations
1987

A pilot clinical trial of the toxicity and immunorestorative effects of T cell reconstituting factor (SR 270258) in immunosuppressed cancer patients

Murray, J. L., Reuben, J. M., Smith, T. L., Gehan, E. A., Koretz, S. M. & Hersh, E. M., Feb 1987, In : Journal of Biological Response Modifiers. 6, 1, p. 56-68 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Clinical parameters related to optimal tumor localization of indium-111-labeled mouse antimelanoma monoclonal antibody ZME-018

Murray, J. L., Rosenblum, M. G., Lamki, L., Glenn, H. J., Krizan, Z., Hersh, E. M., Plager, C. E., Bartholomew, R. M., Unger, M. W. & Carlo, D. J., Apr 1 1987, In : Journal of Nuclear Medicine. 28, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Decreased 5′nucleotidase activity in suppressor (OKT8) T lymphocytes from homosexuals with AIDS-related complex: Nonassociation with enhanced deoxynucleoside toxicity

Murray, J. L., Bywaters, D. W., Reuben, J. M., Mansell, P. W. & Hersh, E. M., Jan 1987, In : Clinical Immunology and Immunopathology. 42, 1, p. 10-17 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Idiopathic production of interleukin-1 in acquired immune deficiency syndrome

Lepe-Zuniga, J. L., Mansell, P. W. A. & Hersh, E. M., Jan 1 1987, In : Journal of clinical microbiology. 25, 9, p. 1695-1700 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Radioimmunoimaging in malignant melanoma patients with the use of indium-111-labeled antimelanoma monoclonal antibody (ZME-018) to high-molecular-weight antigen

Murray, J. L., Rosenblum, M. G., Lamki, L., Haynie, T. P., Glenn, H. J., Plager, C. E., Unger, M. W., Carlo, D. J. & Hersh, E. M., Apr 2 1987, In : NCI Monographs. No. 3, p. 3-9 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Radioimmunological imaging of metastatic prostatic cancer with 111indium-labeled monoclonal antibody PAY 276

Babaian, R. J., Murray, J. L., Lamki, L. M., Haynie, T. P., Hersh, E. M., Rosenblum, M. G., Glenn, H. J., Unger, M. W., Carlo, D. J. & von Eschenbach, A. C., Jan 1 1987, In : Journal of Urology. 137, 3, p. 439-443 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Synergism between alpha-interferon and interleukin-2-activated killer cells: In vitro studies

Di Raimondo, F., LaPushin, R. & Hersh, E. M., Jan 1 1987, In : Acta Haematologica. 78, SUPPL. 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
1986

Antibody development to viral and allogeneic tumor cell-associated antigens in patients with malignant melanoma and ovarian carcinoma treated with lysates of virus-infected tumor cells

Savage, H. E., Rossen, R. D., Hersh, E. M., Freedman, R. S., Bowen, J. M. & Plager, C., Apr 1 1986, In : Cancer Research. 46, p. 2127-2133 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

A phase I study of intravenous azimexon therapy in human cancer

Patt, Y. Z., Hersh, E. M., Reuben, J., Claghorn, L. & Mavligit, G., Aug 1986, In : Journal of Biological Response Modifiers. 5, 4, p. 313-318 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Centrifugal elutriation as a method for isolation of large numbers of functionally intact human peripheral blood monocytes

Turpin, J., Hester, J. P., Hersh, E. M. & Lopez‐Berestein, G., 1986, In : Journal of Clinical Apheresis. 3, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
15 Scopus citations

Clinical pharmacology of the biological response modifier maleic anhydride divinyl ether copolymer (MVE-2)

Rosenblum, M. G., Rios, A. M. & Hersh, E. M., Dec 1 1986, In : Cancer Chemotherapy And Pharmacology. 18, 3, p. 243-246 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Decreased adenosine deaminase (ADA) and 5′nucleotidase (5NT) activity in peripheral blood T cells in hodgkin disease

Murray, J. L., Perez‐Soler, R., Bywaters, D. & Hersh, E. M., Jan 1986, In : American Journal of Hematology. 21, 1, p. 57-66 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effect of azimexon therapy on host defense parameters and disease-associated symptoms in the acquired immune deficiency syndrome (AIDS) and aids-related complex (ARC)

Patt, Y. Z., Mansell, P. W. A., Reuben, J. M., Claghorn, L., Li, S., Gehan, E. & Hersh, E. M., Jan 1 1986, In : AIDS Research. 2, 3, p. 191-209 19 p.

Research output: Contribution to journalArticle

1 Scopus citations

Enhanced serological and virological findings of epstein-barr virus in patients with aids and aids-related complex

Sumaya, C. V., Boswell, R. N., Ench, Y., Kisner, D. L., Hersh, E. M., Reuben, J. M., Peter, P. W., Sumaya, C. V., Boswell, R. N., Ench, Y., Kisner, D. L., Hersh, E. M., Reuben, J. M., Peter, P. W., Sumaya, C. V., Boswell, R. N., Ench, Y., Kisner, D. L., Hersh, E. M., Reuben, J. M. & 1 others, Peter, P. W., Nov 1986, In : Journal of Infectious Diseases. 154, 5, p. 864-870 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Initial clinical studies with copovithane

Hortobagyi, G. N., Hersh, E. M., Papadopoulos, N. E. J., Frye, D., Rios, A., Reuben, J. M., Plager, C., Rosenblum, M. & Quesada, J., Aug 1986, In : Journal of Biological Response Modifiers. 5, 4, p. 319-329 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
23 Scopus citations

Modulation in vitro of immune parameters in homosexual males with the preclinical complex of symptoms related to acquired immune deficiency syndrome by azimexon

Patt, Y. Z., Mavligit, G. M., Reuben, J., Mansell, P. W. A., Li, S., Newell, G., Talpaz, M. & Hersh, E. M., Jun 1986, In : Journal of Biological Response Modifiers. 5, 3, p. 263-269 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Phase i study of 2-amino-5-bromo-6-phenyl-4(3h)-pyrimidinone (ABPP), an oral interferon inducer, in cancer patients

Rios, A., Stringfellow, D. A., Fitzpatrick, F. A., Reele, S. B., Gutknecht, G. D. & Hersh, E. M., Aug 1986, In : Journal of Biological Response Modifiers. 5, 4, p. 330-338 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Phase I study of multiple dose intramuscularly administered recombinant gamma interferon

Kurzrock, R., Quesada, J. R., Talpaz, M., Hersh, E. M., Reuben, J. M., Sherwin, S. A. & Gutterman, J. U., Jan 1 1986, In : Journal of Clinical Oncology. 4, 7, p. 1101-1109 9 p.

Research output: Contribution to journalArticle

71 Scopus citations

Prediction of survival by degree of reactivity to BCG in patients with metastatic breast cancer

Hortobagyi, G. N., Buzdar, A. U., Blumenschein, G. R., Yap, H. Y. & Hersh, E. M., Dec 1 1986, In : Developments in biological standardization. 58 Part A, p. 357-364 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Relationship of exposure to human T lymphotropic virus and t helper cells in homosexual men

Reuben, J. M., Larocco, J. M., Gschwind, C. R., Stroud, C., Rios, A., Hersh, E. M. & Mansell, P. W. A., Jan 1 1986, In : AIDS Research. 2, 2, p. 117-126 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Serologic studies in hairy cell leukemia: High prevalence of Epstein-Barr and cytomegalovirus antibodies and absence of human T-cell lymphotrophic viruses antibodies

Quesada, J. R., Reuben, J., Hopfer, R. L., Mundon, F. K. & Hersh, E. M., 1986, In : Leukemia Research. 10, 10, p. 1169-1173 5 p.

Research output: Contribution to journalArticle

11 Scopus citations