Evan M Hersh

  • 19105 Citations
  • 67 h-Index
1965 …2021
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Research Output 1965 2017

  • 19105 Citations
  • 67 h-Index
  • 490 Article
  • 48 Chapter
  • 3 Letter
  • 1 Conference contribution
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Article
1986
28 Citations (Scopus)

Antibody development to viral and allogeneic tumor cell-associated antigens in patients with malignant melanoma and ovarian carcinoma treated with lysates of virus-infected tumor cells

Savage, H. E., Rossen, R. D., Hersh, E. M., Freedman, R. S., Bowen, J. M. & Plager, C., 1986, In : Cancer Research. 46, 4 II, p. 2127-2133 7 p.

Research output: Contribution to journalArticle

Oncogenic Viruses
Melanoma
Carcinoma
Antigens
Viruses
5 Citations (Scopus)

A phase I study of intravenous azimexon therapy in human cancer

Patt, Y. Z., Hersh, E. M., Reuben, J., Claghorn, L. & Mavligit, G., 1986, In : Journal of Biological Response Modifiers. 5, 4, p. 313-318 6 p.

Research output: Contribution to journalArticle

Azirines
Aziridines
Immunologic Adjuvants
Drug Evaluation
Lymphocyte Activation
15 Citations (Scopus)

Centrifugal elutriation as a method for isolation of large numbers of functionally intact human peripheral blood monocytes

Turpin, J., Hester, J. P., Hersh, E. M. & Lopez-Berestein, G., 1986, In : Journal of Clinical Apheresis. 3, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

Monocytes
Population
Lipopolysaccharides
Plateletpheresis
Monoclonal Antibodies
15 Citations (Scopus)
Hydrogen Peroxide
Monocytes
Macrophages
Interferons
Lipopolysaccharides
7 Citations (Scopus)

Clinical pharmacology of the biological response modifier maleic anhydride divinyl ether copolymer (MVE-2)

Rosenblum, M. G., Rios, A. M. & Hersh, E. M., Dec 1986, In : Cancer Chemotherapy and Pharmacology. 18, 3, p. 243-246 4 p.

Research output: Contribution to journalArticle

Pyran Copolymer
Clinical Pharmacology
Immunologic Factors
Plasmas
Half-Life
15 Citations (Scopus)

Decreased adenosine deaminase (ADA) and 5' nucleotidase (5NT) activity in peripheral blood T cells in Hodgkin disease

Murray, J. L., Perez-Soler, R., Bywaters, D. & Hersh, E. M., 1986, In : American Journal of Hematology. 21, 1, p. 57-66 10 p.

Research output: Contribution to journalArticle

5'-Nucleotidase
Adenosine Deaminase
Purine-Nucleoside Phosphorylase
Hodgkin Disease
Blood Cells
1 Citation (Scopus)

Effect of azimexon therapy on host defense parameters and disease-associated symptoms in the acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC)

Patt, Y. Z., Mansell, P. W. A., Reuben, J. M., Claghorn, L., Li, S., Gehan, E. & Hersh, E. M., 1986, In : AIDS Research. 2, 3, p. 191-209 19 p.

Research output: Contribution to journalArticle

Azirines
Graft vs Host Reaction
Aziridines
AIDS-Related Complex
Lymphocyte Activation
61 Citations (Scopus)

Enhanced serological and virological findings of Epstein-Barr virus in patients with AIDS and AIDS-related complex

Sumaya, C. V., Boswell, R. N., Ench, Y., Kisner, D. L., Hersh, E. M., Reuben, J. M. & Mansell, P. W., 1986, In : Journal of Infectious Diseases. 154, 5, p. 864-870 7 p.

Research output: Contribution to journalArticle

AIDS-Related Complex
Human Herpesvirus 4
Acquired Immunodeficiency Syndrome
Antibody Formation
Control Groups
4 Citations (Scopus)

Initial clinical studies with copovithane

Hortobagyi, G. N., Hersh, E. M., Papadopoulos, N. E. J., Frye, D., Rios, A., Reuben, J. M., Plager, C., Rosenblum, M. & Quesada, J., 1986, In : Journal of Biological Response Modifiers. 5, 4, p. 319-329 11 p.

Research output: Contribution to journalArticle

Immunologic Cytotoxicity
Drug Tolerance
Povidone
Drug Evaluation
Carbamates
23 Citations (Scopus)
Lymphocyte Activation
Concanavalin A
Prostaglandins E
Dinoprostone
Indomethacin
6 Citations (Scopus)

Modulation in vitro of immune parameters in homosexual males with the preclinical complex of symptoms related to acquired immune deficiency syndrome by azimexon

Patt, Y. Z., Mavligit, G. M., Reuben, J., Mansell, P. W., Newell, G., Talpaz, M. & Hersh, E. M., 1986, In : Journal of Biological Response Modifiers. 5, 3, p. 263-269 7 p.

Research output: Contribution to journalArticle

Azirines
Graft vs Host Reaction
T Lymphocyte Differentiation Antigens
Aziridines
Homosexuality
9 Citations (Scopus)

Phase I study of 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP), an oral interferon inducer, in cancer patients

Rios, A., Stringfellow, D. A., Fitzpatrick, F. A., Reele, S. B., Gutknecht, G. D. & Hersh, E. M., 1986, In : Journal of Biological Response Modifiers. 5, 4, p. 330-338 9 p.

Research output: Contribution to journalArticle

Pyrimidinones
Interferon Inducers
Drug Evaluation
Cytosine
Immunologic Factors
71 Citations (Scopus)

Phase I study of multiple dose intramuscularly administered recombinant gamma interferon

Kurzrock, R., Quesada, J. R., Talpaz, M., Hersh, E. M., Reuben, J. M., Sherwin, S. A. & Gutterman, J. U., 1986, In : Journal of Clinical Oncology. 4, 7, p. 1101-1109 9 p.

Research output: Contribution to journalArticle

Interferon-gamma
Natural Killer Cells
B-Cell Antigen Receptors
Agranulocytosis
Maximum Tolerated Dose
1 Citation (Scopus)

Prediction of survival by degree of reactivity to BCG in patients with metastatic breast cancer

Hortobagyi, G. N., Buzdar, A. U., Blumenschein, G. R., Yap, H. Y. & Hersh, E. M., 1986, In : Developments in Biological Standardization. 58 Part A, p. 357-364 8 p.

Research output: Contribution to journalArticle

BCG Vaccine
Mycobacterium bovis
Breast Neoplasms
Neoplasm Metastasis
Survival
1 Citation (Scopus)

Relationship of exposure to human T lymphotropic virus and T helper cells in homosexual men

Reuben, J. M., LaRocco, J. M., Gschwind, C. R., Stroud, C., Rios, A., Hersh, E. M. & Mansell, P. W., 1986, In : AIDS Research. 2, 2, p. 117-126 10 p.

Research output: Contribution to journalArticle

Viral Antibodies
Deltaretrovirus
HIV Antibodies
Kaposi's Sarcoma
Homosexuality
11 Citations (Scopus)

Serologic studies in hairy cell leukemia: High prevalence of Epstein-Barr and cytomegalovirus antibodies and absence of human T-cell lymphotrophic viruses antibodies

Quesada, J. R., Reuben, J., Hopfer, R. L., Mundon, F. K. & Hersh, E. M., 1986, In : Leukemia Research. 10, 10, p. 1169-1173 5 p.

Research output: Contribution to journalArticle

Hairy Cell Leukemia
Cytomegalovirus
Viruses
T-Lymphocytes
Antibodies
6 Citations (Scopus)

Terminal transferase in leukemias by flow cytometry

Loftin, K. C., Reuben, J. M., Dalton, W., Hersh, E. M. & Sujansky, D., 1986, In : Diagnostic Immunology. 4, 3, p. 165-169 5 p.

Research output: Contribution to journalArticle

DNA Nucleotidyltransferases
Lymphoid Leukemia
DNA Nucleotidylexotransferase
Flow cytometry
Transferases
39 Citations (Scopus)

Thymosin α1 and thymosin β4 in serum: Comparison of normal, cord, homosexual and AIDS serum

Naylor, P. H., Friedman-Kien, A., Hersh, E. M., Erdos, M. & Goldstein, A. L., 1986, In : International Journal of Immunopharmacology. 8, 7, p. 667-676 10 p.

Research output: Contribution to journalArticle

Thymosin
Acquired Immunodeficiency Syndrome
Serum
Peptides
Sexual Minorities
35 Citations (Scopus)

Treatment of hairy cell leukemia with alpha interferons

Quesada, J. R., Gutterman, J. U. & Hersh, E. M., 1986, In : Cancer. 57, 8 SUPPL., p. 1678-1680 3 p.

Research output: Contribution to journalArticle

Hairy Cell Leukemia
Interferon-alpha
Interferons
Therapeutics
Bone Marrow
169 Citations (Scopus)

Treatment of hairy cell leukemia with recombinant α-interferon

Quesada, J. R., Hersh, E. M., Manning, J., Reuben, J., Keating, M., Schnipper, E., Itri, L. & Gutterman, J. U., 1986, In : Blood. 68, 2, p. 493-497 5 p.

Research output: Contribution to journalArticle

Hairy Cell Leukemia
Interferons
Tumors
Cells
Blood
1985
20 Citations (Scopus)

Abnormal lymphocyte response to exogenous interleukin-2 in homosexuals with acquired immune deficiency syndrome (AIDS) and AIDS related complex (ARC)

Murray, J. L., Hersh, E. M., Reuben, J. M., Munn, C. G. & Mansell, P. W., 1985, In : Clinical and Experimental Immunology. 60, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

Interleukin-2
Acquired Immunodeficiency Syndrome
Lymphocytes
Prodromal Symptoms
Heterosexuality
2 Citations (Scopus)

Cytoplasmic IgM in leukemic B cells by flow cytometry

Loftin, K. C., Reuben, J. M., Hersh, E. M. & Sujansky, D., 1985, In : Leukemia Research. 9, 11, p. 1379-1387 9 p.

Research output: Contribution to journalArticle

Immunoglobulin M
Flow Cytometry
B-Lymphocytes
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
39 Citations (Scopus)

Distribution of technetium-99m-labeled multilamellar liposomes in patients with Hodgkin's disease

Perez-Soler, R., Lopez-Berestein, G., Kasi, L. P., Cabanillas, F., Jahns, M., Glenn, H., Hersh, E. M. & Haynie, T., 1985, In : Journal of Nuclear Medicine. 26, 7, p. 743-749 7 p.

Research output: Contribution to journalArticle

Technetium
Hodgkin Disease
Liposomes
Bone Marrow
Lung
41 Citations (Scopus)

Elevated adenosine deaminase and purine nucleoside phosphorylase activity in peripheral blood null lymphocytes from patients with acquired immune deficiency syndrome

Murray, J. L., Loftin, K. C., Munn, C. G., Reuben, J. M., Mansell, P. W. & Hersh, E. M., 1985, In : Blood. 65, 6, p. 1318-1324 7 p.

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
Null Lymphocytes
Adenosine Deaminase
Lymphocytes
Acquired Immunodeficiency Syndrome
9 Citations (Scopus)

IL-2 production and response in vitro by the leukocytes of patients with acquired immune deficiency syndrome

Reuben, J. M., Hersh, E. M., Murray, J. L., Munn, C. G., Mehta, S. R. & Mansell, P. W., 1985, In : Lymphokine Research. 4, 2, p. 103-116 14 p.

Research output: Contribution to journalArticle

Immunologic Receptors
CD27 Antigens
Interleukin-2 Receptors
Phytohemagglutinins
Lymphatic Diseases
36 Citations (Scopus)

Immune recovery following allogeneic bone marrow transplantation

Zander, A. R., Reuben, J. M., Johnston, D., Vellekoop, L., Dicke, K. A., Yau, J. C. & Hersh, E. M., 1985, In : Transplantation. 40, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

Homologous Transplantation
Bone Marrow Transplantation
CD4-Positive T-Lymphocytes
Helper-Inducer T-Lymphocytes
Erythrocytes
22 Citations (Scopus)

Impaired in vitro interferon, blastogenic, and natural killer cell responses to viral stimulation in acquired immune deficiency syndrome

Hersh, E. M., Gutterman, J. U., Spector, S., Friedman, H., Greenberg, S. B., Reuben, J. M., LaPushin, R., Matza, M. & Mansell, P. W., 1985, In : Cancer Research. 45, 1, p. 406-410 5 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Interferons
Acquired Immunodeficiency Syndrome
Human Herpesvirus 1
Viruses
24 Citations (Scopus)

Increased labeling of human melanoma cells in vitro using combinations of monoclonal antibodies recognizing separate cell surface antigenic determinants

Krizan, Z., Murray, J. L., Hersh, E. M., Rosenblum, M. G., Glenn, H. J., Gschwind, C. R. & Carlo, D. J., 1985, In : Cancer Research. 45, 10, p. 4904-4909 6 p.

Research output: Contribution to journalArticle

Epitopes
Melanoma
Monoclonal Antibodies
Fluorescence
Melanoma-Specific Antigens
6 Citations (Scopus)

In vitro modulation of purine enzyme metabolism and lymphocyte surface marker expression by thymosin fraction 5 in homosexual males

Murray, J. L., Reuben, J. M., Munn, C. G., Newell, G., Mansell, P. W. A. & Hersh, E. M., 1985, In : International Journal of Immunopharmacology. 7, 5, p. 661-669 9 p.

Research output: Contribution to journalArticle

Thymosin
Null Lymphocytes
Purine-Nucleoside Phosphorylase
Lymphocytes
Acquired Immunodeficiency Syndrome
341 Citations (Scopus)

Liposomal amphotericin B for the treatment of systemic fungal infections in patients with cancer: A preliminary study

Lopez-Berestein, G., Fainstein, V., Hopfer, R., Mehta, K., Sullivan, M. P., Keating, M., Rosenblum, M. G., Mehta, R., Luna, M. & Hersh, E. M., 1985, In : Journal of Infectious Diseases. 151, 4, p. 704-710 7 p.

Research output: Contribution to journalArticle

Mycoses
Neoplasms
Therapeutics
Chills
Amphotericin B
52 Citations (Scopus)

Modification of human leukocyte interferon pharmacology with a monoclonal antibody

Rosenblum, M. G., Unger, B. W., Gutterman, J. U., Hersh, E. M., David, G. S. & Frincke, J. M., 1985, In : Cancer Research. 45, 6, p. 2421-2424 4 p.

Research output: Contribution to journalArticle

Interferon-alpha
Interferons
Monoclonal Antibodies
Pharmacology
Antiviral Agents
59 Citations (Scopus)

Pharmacokinetics of 111ln-labeled Anti-p97 Monoclonal Antibody in Patients with Metastatic Malignant Melanoma

Murray, J. L., Haynie, T. P., Hersh, E. M., Glenn, H. J., Jahns, M. F., Benjamin, R. S., Frincke, J. M. & Carlo, D. J., May 1 1985, In : Cancer Research. 45, 5, p. 2382-2386 5 p.

Research output: Contribution to journalArticle

Melanoma
Pharmacokinetics
Monoclonal Antibodies
Antibodies
Liver
7 Citations (Scopus)

Purification and characterization of high-affinity cyclic adenosine 5'-monophosphate phosphodiesterases from human acute myelogenous leukemic cells

Onali, P., Strada, S. J., Chang, L., Epstein, P. M., Hersh, E. M. & Thompson, W. J., 1985, In : Cancer Research. 45, 3, p. 1384-1391 8 p.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
Cyclic AMP
Guanosine Monophosphate
Phosphoric Diester Hydrolases
Enzymes
101 Citations (Scopus)

Radioimmunoimaging in Malignant Melanoma with 111ln-labeled Monoclonal Antibody 96.5

Murray, J. L., Rosenblum, M. G., Plager, C. E., Haynie, T. P., Jahns, M. F., Glenn, H. J., Lamki, L., Benjamin, R. S., Papadopoulos, N., Boddie, A. W., Hersh, E. M., Sobol, R. E., Bartholomew, R. M., Frincke, J. M., David, G. S., Carlo, D. J. & Murray, J. L., May 1 1985, In : Cancer Research. 45, 5, p. 2376-2381 6 p.

Research output: Contribution to journalArticle

Radioimmunodetection
Melanoma
Monoclonal Antibodies
Tissue Extracts
Antibodies
49 Citations (Scopus)

Risk factor analysis among men referred for possible acquired immune deficiency syndrome

Newell, G. R., Mansell, P. W. A., Wilson, M. B., Lynch, H. K., Spitz, M. R. & Hersh, E. M., 1985, In : Preventive Medicine. 14, 1, p. 81-91 11 p.

Research output: Contribution to journalArticle

Statistical Factor Analysis
Acquired Immunodeficiency Syndrome
Odds Ratio
Cannabis
Nitrites
8 Citations (Scopus)

Superoxide anion (O2-) production by peripheral blood monocytes in Hodgkin's disease and malignant lymphoma

Perez-Soler, R., Lopez-Berestein, G., Cabanillas, F., McLaughlin, P. & Hersh, E. M., 1985, In : Journal of Clinical Oncology. 3, 5, p. 641-645 5 p.

Research output: Contribution to journalArticle

Hodgkin Disease
Superoxides
Monocytes
Lymphoma
Opportunistic Infections
86 Citations (Scopus)

Treatment of acquired immunodeficiency syndrome-related Kaposi's sarcoma with lymphoblastoid interferon

Rios, A., Mansell, P. W. A., Newell, G. R., Reuben, J. M., Hersh, E. M. & Gutterman, J. U., 1985, In : Journal of Clinical Oncology. 3, 4, p. 506-512 7 p.

Research output: Contribution to journalArticle

Kaposi's Sarcoma
Interferon-alpha
Acquired Immunodeficiency Syndrome
Asthenia
Interferons
46 Citations (Scopus)

Volatile nitrites. Use and adverse effects related to the current epidemic of the acquired immune deficiency syndrome

Newell, G. R., Mansell, P. W. A., Spitz, M. R., Reuben, J. M. & Hersh, E. M., May 1985, In : American Journal of Medicine. 78, 5, p. 811-816 6 p.

Research output: Contribution to journalArticle

Nitrites
Acquired Immunodeficiency Syndrome
Life Style
Nitroso Compounds
Teratogens
1984
58 Citations (Scopus)

Adjuvant chemotherapy with fluorouracil, doxorubicin, and cyclophosphamide, with or without Bacillus Calmette‐Guerin and with or without irradiation in operable breast cancer a prospective randomized trial

Buzdar, A. U., Blumenschein, G. R., Smith, T. L., Powell, K. C., Hortobagyi, G. N., Yap, H. Y., Schell, F. C., Barnes, B. C., Ames, F. C., Martin, R. G. & Hersh, E. M., 1984, In : Cancer. 53, 3, p. 384-389 6 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Fluorouracil
Doxorubicin
Cyclophosphamide
Bacillus
672 Citations (Scopus)

Alpha interferon for induction of remission in hairy-cell leukemia

Quesada, J. R., Reuben, J., Manning, J. T., Hersh, E. M. & Gutterman, J. U., 1984, In : New England Journal of Medicine. 310, 1, p. 15-18 4 p.

Research output: Contribution to journalArticle

Remission Induction
Hairy Cell Leukemia
Interferon-alpha
Agranulocytosis
Thrombocytopenia
2 Citations (Scopus)

Analysis of the antitumor agent Bay i 7433 (copovithane) in plasma and urine by high performance liquid chromatography

Rosenblum, M. G., Hersh, E. M., Wingender, W. & Hersh, E. M., 1984, In : Journal of Liquid Chromatography. 7, 1, p. 159-166 8 p.

Research output: Contribution to journalArticle

High performance liquid chromatography
Antineoplastic Agents
High Pressure Liquid Chromatography
Urine
Plasmas
10 Citations (Scopus)

Biologic therapy of hairy cell leukemia

Quesada, J. R., Hersh, E. M. & Gutterman, J. U., 1984, In : Seminars in Oncology. 11, 4 SUPPL. 2, p. 507-510 4 p.

Research output: Contribution to journalArticle

Leukapheresis
Hairy Cell Leukemia
Interferon Type I
Biological Therapy
Blood Transfusion
103 Citations (Scopus)

Clinical Pharmacology of 99mTc-labeled Liposomes in Patients with Cancer

Rosenblum, M. G., Mavligit, G. M., Hersh, E. M., Kasi, L., Haynie, T., Glenn, H., Jahns, M., Mehta, R. & Lopez-Berestein, G., Jan 1 1984, In : Cancer Research. 44, 1, p. 375-378 4 p.

Research output: Contribution to journalArticle

Clinical Pharmacology
Liposomes
Neoplasms
Half-Life
Spleen
19 Citations (Scopus)

Decreased 5' nucleotidase activity in lymphocytes from asymptomatic sexually active homosexual men and patients with the acquired immune deficiency syndrome

Murray, J. L., Reuben, J. M., Munn, C. G., Mansell, P. W., Newell, G. R. & Hersh, E. M., 1984, In : Blood. 64, 5, p. 1016-1021 6 p.

Research output: Contribution to journalArticle

5'-Nucleotidase
Lymphocytes
Acquired Immunodeficiency Syndrome
CD38 Antigens
CD8-Positive T-Lymphocytes
19 Citations (Scopus)

Delayed hypersensitivity responses of cancer patients to recall antigens using a new 'Multitest' applicator

Reuben, J. M. & Hersh, E. M., 1984, In : Annals of Allergy. 53, 5, p. 390-394 5 p.

Research output: Contribution to journalArticle

Delayed Hypersensitivity
Antigens
Neoplasms
Immunocompetence
Cellular Immunity
9 Citations (Scopus)

Depression of murine natural killer cell cytotoxicity by isobutyl nitrite

Lotzová, E., Savary, C. A., Hersh, E. M., Khan, A. A. & Rosenblum, M., Aug 1984, In : Cancer Immunology, Immunotherapy. 17, 2, p. 130-134 5 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Acquired Immunodeficiency Syndrome
isobutyl nitrite
T-Cell Lymphoma
Immunosuppressive Agents
19 Citations (Scopus)

Distribution and pharmacology of intravenous 99mTc-labeled multilamellar liposomes in rats and mice

Kasi, L. P., Lopez-Berestein, G., Mehta, K., Rosenblum, M., Glenn, H. J., Haynie, T. P., Mavligit, G. & Hersh, E. M., 1984, In : International Journal of Nuclear Medicine and Biology. 11, 1, p. 35-37 3 p.

Research output: Contribution to journalArticle

Liposomes
Pharmacology
Lung
Injections
Liver
2 Citations (Scopus)

Expression of T cell surface antigens by mitogen stimulated lymphocytes from patients with AIDS

Munn, C. G., Reuben, J. M. & Hersh, E. M., 1984, In : Federation Proceedings. 43, 3

Research output: Contribution to journalArticle

Surface Antigens
Mitogens
Acquired Immunodeficiency Syndrome
Lymphocytes
T-Lymphocytes

Expression of T cell surface antigens by mitogen stimulated lymphocytes from patients with AIDS

Munn, C. G., Reuben, J. M. & Hersh, E. M., 1984, In : Federation Proceedings. 43, 7

Research output: Contribution to journalArticle

Surface Antigens
Mitogens
Acquired Immunodeficiency Syndrome
Lymphocytes
T-Lymphocytes
18 Citations (Scopus)

Immunological characterizations of patients with acquired immune deficiency syndrome, acquired immune deficiency syndrome-related symptom complex, and a related life-style

Hersh, E. M., Mansell, P. W. A., Hersh, E. M., Rios, A. & Newell, G. R., 1984, In : Cancer Research. 44, 12 I, p. 5894-5901 8 p.

Research output: Contribution to journalArticle

Life Style
Acquired Immunodeficiency Syndrome
AIDS-Related Complex
Kaposi's Sarcoma
Opportunistic Infections