Evan M Hersh

  • 19105 Citations
  • 67 h-Index
1965 …2021
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Research Output 1965 2017

  • 19105 Citations
  • 67 h-Index
  • 490 Article
  • 48 Chapter
  • 3 Letter
  • 1 Conference contribution
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Article
1976
1 Citation (Scopus)

Assessment of immunocompetence in the routine evaluation of the cancer patient

Hersh, E. M., Gutterman, J. U. & Mavligit, G. M., 1976, In : Southern Medical Journal. 69, 3, p. 356-359 4 p.

Research output: Contribution to journalArticle

Immunologic Techniques
Immunocompetence
Mononuclear Phagocyte System
Delayed Hypersensitivity
Skin Tests
20 Citations (Scopus)

BCG vaccine and its derivatives. Potential, practical considerations, and precautions in human cancer immunotherapy

Hersh, E. M., Gutterman, J. U. & Mavligit, G. M., 1976, In : Journal of the American Medical Association. 235, 6, p. 646-650 5 p.

Research output: Contribution to journalArticle

BCG Vaccine
Immunotherapy
Neoplasms
Head and Neck Neoplasms
Clinical Trials

Cancer Immunotherapy Reply

Hersh, E. M., 1976, In : Journal of the American Medical Association. 236, 9, p. 1012-1013 2 p.

Research output: Contribution to journalArticle

Immunotherapy
Neoplasms
66 Citations (Scopus)

Chemoimmunotherapy of advanced breast cancer: prolongation of remission and survival with BCG.

Gutterman, J. U., Cardenas, J. O., Blumenschein, G. R., Hortobagyi, G., Burgess, M. A., Livingston, R. B., Mavligit, G. M., Freireich, E. J., Gottlieb, J. A. & Hersh, E. M., Nov 20 1976, In : BMJ (Clinical research ed.). 2, 6046, p. 1222-1225 4 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Fluorouracil
Doxorubicin
Cyclophosphamide
Breast Neoplasms
11 Citations (Scopus)

Chemoimmunotherapy of human solid tumors

Gutterman, J. U., Mavligit, G. M. & Hersh, E. M., 1976, In : Medical Clinics of North America. 60, 3, p. 441-462 22 p.

Research output: Contribution to journalArticle

Neoplasms
Immunotherapy
Immunologic Monitoring
Drug Therapy
Lung Neoplasms
7 Citations (Scopus)

Complement activation in vivo in cancer patients receiving C. parvum immunotherapy

Biran, H., Moake, J. L., Reed, R. C., Gutterman, J. U., Hersh, E. M., Freireich, E. J. & Mavligit, G. M., 1976, In : British Journal of Cancer. 34, 5, p. 493-499 7 p.

Research output: Contribution to journalArticle

Complement Activation
Immunotherapy
Neoplasms
Alternative Complement Pathway
Complement Factor B

Complement activation in vivo in cancer patients receiving C. Parvum immunotherapy

Biran, H., Moake, J. L., Reed, R. C., Gutterman, J. U., Hersh, E. M., Freireich, E. J. & Mavligit, G. M., 1976, In : British Journal of Cancer. 34, 5, p. 493-499 7 p.

Research output: Contribution to journalArticle

Complement Activation
Immunotherapy
Neoplasms
Alternative Complement Pathway
Complement Factor B
79 Citations (Scopus)

Cyclic adenosine 3': 5' monophosphate phosphodiesterase. Distinct forms in human lymphocytes and monocytes

Thompson, W. J., Ross, C. P., Pledger, W. J., Strada, S. J., Banner, R. L. & Hersh, E. M., 1976, In : Journal of Biological Chemistry. 251, 16, p. 4922-4929 8 p.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
Lymphocytes
Phosphoric Diester Hydrolases
Adenosine
Monocytes

Developmental therapy in adult acute leukemia

Freireich, E. J., Bodey, G. P., McCredie, K. B., Hersh, E. M., Gehan, E. A., Hart, J., Gutterman, J. U., Rodriguez, V., Smith, T. & Hester, J. P., 1976, In : Archives of Internal Medicine. 136, 12, p. 1417-1421 5 p.

Research output: Contribution to journalArticle

BCG Vaccine
Age Factors
Acute Disease
Mycobacterium bovis
Immunotherapy
23 Citations (Scopus)

Developmental Therapy in Adult Acute Leukemia

Freireich, E. J., Bodey, G. P., Mccredie, K. B., Hersh, E. M., Gehan, E. A., Hart, J., Gutterman, J. U., Rodriguez, V., Smith, T. & Hester, J. P., 1976, In : Archives of Internal Medicine. 136, 12, p. 1417-1421 5 p.

Research output: Contribution to journalArticle

Leukemia
Therapeutics
7 Citations (Scopus)
Dinitrochlorobenzene
Delayed Hypersensitivity
Mycobacterium bovis
Melanoma
Immunotherapy
10 Citations (Scopus)

Effect of haematological malignancies and their treatment on host defence factors.

Hersh, E. M., Gutterman, J. U. & Mavligit, G. M., Jun 1976, In : Clinics in Haematology. 5, 2, p. 425-448 24 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Leukemia
Lymphoma
Immunocompetence
Active Immunotherapy
16 Citations (Scopus)

Evaluation of BCG administered by scarification for immunotherapy of metastatic hepatocarcinoma in the guinea pig

Hanna, M. G., Peters, L. C., Gutterman, J. U. & Hersh, E. M., 1976, In : Journal of the National Cancer Institute. 56, 5, p. 1013-1017 5 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Immunotherapy
Guinea Pigs
Lymph Nodes
Neoplasm Metastasis
6 Citations (Scopus)

Fetal antigens in human leukemia

Granatek, C. H., Hanna, M. G., Hersh, E. M., Gutterman, J. U., Mavligit, G. M. & Candler, E. L., 1976, In : Cancer Research. 36, 9

Research output: Contribution to journalArticle

Leukemia
Antigens
Liver
Immune Sera
Bone Marrow
6 Citations (Scopus)

Fetal Antigens in Human Leukemia

Granatek, C. H., Hanna, M. G., Hersh, E. M., Gutterman, J. U., Mavligit, G. M. & Candler, E. L., 1976, In : Cancer Research. 36, p. 3464-3470 7 p.

Research output: Contribution to journalArticle

Leukemia
Antigens
Liver
Immune Sera
Bone Marrow
48 Citations (Scopus)

Immunocompetence, immunodeficiency and prognosis in cancer

Hersh, E. M., Gutterman, J. U. & Mavligit, G. M., 1976, In : Annals of the New York Academy of Sciences. Vol. 276, p. 386-406 21 p.

Research output: Contribution to journalArticle

Immunocompetence
Melanoma
Delayed Hypersensitivity
Antigens
Lymphocytes
31 Citations (Scopus)

Immunodeficiency in cancer and the importance of immune evaluation of the cancer patient

Hersh, E. M., Mavligit, G. M. & Gutterman, J. U., 1976, In : Medical Clinics of North America. 60, 3, p. 623-639 17 p.

Research output: Contribution to journalArticle

Neoplasms
8 Citations (Scopus)

Immunological evaluation of malignant disease. Diagnosis, prognosis, and management.

Hersh, E. M., Mavligit, G. M. & Gutterman, J. U., Oct 11 1976, In : Journal of the American Medical Association. 236, 15, p. 1739-1742 4 p.

Research output: Contribution to journalArticle

Immunologic Deficiency Syndromes
Neoplasm Antigens
Immunosuppression
Immunity
Neoplasms
28 Citations (Scopus)

Immunotherapy of breast cancer, malignant melanoma, and acute leukemia with BCG: Prolongation of disease free interval and survival

Gutterman, J. U., Mavligit, G. M., Burgess, M. A., Cardenas, J. O., Blumenschein, G. R., Gottlieb, J. A., McBride, C. M., McCredie, K. B., Bodey, G. P., Rodriguez, V., Freireich, E. J. & Hersh, E. M., 1976, In : Cancer Immunology, Immunotherapy. 1, 1-2, p. 99-107 9 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Immunotherapy
Disease-Free Survival
Melanoma
Leukemia
16 Citations (Scopus)

IMMUNOTHERAPY OF HUMAN SOLID TUMORS WITH BACILLUS CALMETTE‐GUÉRIN: PROLONGATION OF DISEASE‐FREE INTERVAL AND SURVIVAL IN MALIGNANT MELANOMA, BREAST, AND COLORECTAL CANCER

Gutterman, J. U., Mavligit, G. M., Blumenshein, G., Burgess, M. A., McBride, C. M. & Hersh, E. M., 1976, In : Annals of the New York Academy of Sciences. 277, 1, p. 135-159 25 p.

Research output: Contribution to journalArticle

BCG Vaccine
Dacarbazine
Rectal Neoplasms
Mycobacterium bovis
Fluorouracil
9 Citations (Scopus)

Immunotherapy of leukemia

Hersh, E. M., Gutterman, J. U. & Mavligit, G. M., 1976, In : Medical Clinics of North America. 60, 5, p. 1019-1042 24 p.

Research output: Contribution to journalArticle

Immunotherapy
Leukemia
Active Immunotherapy
methanol extraction residue (MER) tubercle bacillus fraction
Neoplasm Antigens
28 Citations (Scopus)

Inhibition of drug metabolizing enzymes in the rat after Bacillus Calmette Guerin treatment

Farquhar, D., Loo, T. L., Gutterman, J. U., Hersh, E. M. & Luna, M. A., 1976, In : Biochemical Pharmacology. 25, 13, p. 1529-1535 7 p.

Research output: Contribution to journalArticle

Bacilli
Mycobacterium bovis
Rats
Aniline Hydroxylase
Enzymes
72 Citations (Scopus)

Inhibition of drug-metabolizing enzymes in the rat after bacillus calmette-guérin treatment

Farquhar, D., Li Loo, T., Gutterman, J. U., Hersh, E. M. & Luna, M. A., Jul 1 1976, In : Biochemical Pharmacology. 25, 13, p. 1529-1535 7 p.

Research output: Contribution to journalArticle

Bacilli
Bacillus
Rats
Aniline Hydroxylase
Enzymes
3 Citations (Scopus)

Inhibition of human lymphoma cell line colony formation by lymphocytes from patients with lymphoma and cancer hospital employees

Drewinko, B., Mavligit, G. M., Ambus, U. & Hersh, E. M., 1976, In : Cancer. 37, 6, p. 2929-2937 9 p.

Research output: Contribution to journalArticle

Cancer Care Facilities
Lymphoma
Lymphocytes
Cell Line
Neurofibrosarcoma
28 Citations (Scopus)

In vitro and in vivo studies with thymosin in cancer patients

Schafer, L. A., Goldstein, A. L., Gutterman, J. U. & Hersh, E. M., 1976, In : Annals of the New York Academy of Sciences. Vol. 277, p. 609-620 12 p.

Research output: Contribution to journalArticle

Thymosin
T-cells
Neoplasms
T-Lymphocytes
Lymphocytes
6 Citations (Scopus)

Mononuclear cell content of human solid tumors

Hersh, E. M., Mavligit, G. M., Gutterman, J. U. & Barsales, P. B., 1976, In : Medical and Pediatric Oncology. 2, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Neoplasms
Lymphocytes
Lymphocyte Activation
Mitogens
Microscopy
12 Citations (Scopus)

Partial restoration by in vivo thymosin of E-rosettes and delayed-type hypersensitivity reactions in immunodeficient cancer patients

Schaefer, L. A., Gutterman, J. U., Hersh, E. M., Mavligit, G. M., Dandridge, K., Cohen, G. & Goldstein, A. L., 1976, In : Cancer Immunology, Immunotherapy. 1, 4, p. 259-264 6 p.

Research output: Contribution to journalArticle

Thymosin
Delayed Hypersensitivity
Neoplasms
Thymus Extracts
Poisons
64 Citations (Scopus)

PROLONGATION OF POSTOPERATIVE DISEASE-FREE INTERVAL AND SURVIVAL IN HUMAN COLORECTAL CANCER BY B.C.G. OR B.C.G. PLUS 5-FLUOROURACIL

Mavligit, G., Burgess, M., Seibert, G. B., Jubert, A., Mcbride, C., Gehan, E., Gutterman, J., Khankhanian, N., Speer, J., Martin, R., Copeland, E. & Hersh, E. M., Apr 24 1976, In : The Lancet. 307, 7965, p. 871-876 6 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Fluorouracil
Disease-Free Survival
Colorectal Neoplasms
Lymph Nodes
4 Citations (Scopus)

Specific in vitro binding of radiolabeled antibodies to cell surface antigens: Interaction of antihuman thymocyte globulin with human target cells

Garcia-Rinaldi, R., Rossen, R. D., Hersh, E. M., Kormeier, L. & Butler, W. T., 1976, In : Journal of Immunological Methods. 9, 3-4, p. 235-249 15 p.

Research output: Contribution to journalArticle

Globulins
Thymocytes
Surface Antigens
Antibodies
Antilymphocyte Serum
17 Citations (Scopus)

Treatment of Goodpasture syndrome with cyclophosphamide, prednisone and plasma exchange transfusions

Rossen, R. D., Duffy, J., McCredie, K. B., Reisberg, M. A., Sharp, J. T., Hersh, E. M., Eknoyan, G. & Suki, W. N., 1976, In : Clinical and Experimental Immunology. 24, 1, p. 218-222 5 p.

Research output: Contribution to journalArticle

Anti-Glomerular Basement Membrane Disease
Plasma Exchange
Prednisone
Cyclophosphamide
Antibodies
1975
21 Citations (Scopus)

Adjuvant immunotherapy and chemoimmunotherapy in colorectal cancer of the Dukes C classification. Preliminary clinical results

Mavligit, G. M., Gutterman, J. U., Burgess, M. A., Khankhanian, N., Seibert, G. B., Speer, J. F., Reed, R. C., Jubert, A. V., Martin, R. C., McBride, C. M., Copeland, E. M., Gehan, E. A. & Hersh, E. M., 1975, In : Cancer. 36, 6 sup., p. 2421-2427 7 p.

Research output: Contribution to journalArticle

Immunotherapy
Mycobacterium bovis
Colorectal Neoplasms
Fluorouracil
Recurrence
6 Citations (Scopus)

A rapid method for establishing short-term primary cultures of human tumor cells from fresh tumor biopsies.

Mavligit, G. M., Barsales, P. B., Gutterman, J. U., Mackay, B. & Hersh, E. M., Dec 1975, In : Proceedings of the Society for Experimental Biology and Medicine. 150, 3, p. 597-601 5 p.

Research output: Contribution to journalArticle

Biopsy
Cell culture
Tumors
Cells
Diatrizoate
13 Citations (Scopus)

Cancer and host defense mechanisms.

Hersh, E. M., Gutterman, J. U. & Mavligit, G. M., 1975, In : Pathobiology annual. 5, p. 133-167 35 p.

Research output: Contribution to journalArticle

Immunologic Deficiency Syndromes
Immunosuppression
Antibody Formation
Immunity
T-Lymphocytes

Cancer immunology.

Hersh, E. M., Jan 1975, In : Transactions & studies of the College of Physicians of Philadelphia. 42, 3, p. 234-236 3 p.

Research output: Contribution to journalArticle

Bacterial Vaccines
Neoplasm Antibodies
BCG Vaccine
Propionibacterium acnes
Neoplasm Antigens
2 Citations (Scopus)

CHEMOIMMUNOTHERAPY OF ADULT ACUTE LEUKÆMIA

Peto, R., Galton, D. A. G., Gutterman, J., Hersh, E. M., Gehan, E. A. & Freireich, E., Feb 22 1975, In : The Lancet. 305, 7904, p. 454-455 2 p.

Research output: Contribution to journalArticle

Spontaneous Remission
BCG Vaccine
Prednisone
Acute Myeloid Leukemia
Antineoplastic Agents
17 Citations (Scopus)

Effects of cytotoxic and immunosuppressive agents on the immune system

Bodey, G. P., Hersh, E. M., Valdivieso, M., Feid, R. & Rodriguez, V., 1975, In : Postgraduate Medicine. 58, 7, p. 67-74 8 p.

Research output: Contribution to journalArticle

Cytotoxins
Immunosuppressive Agents
Immune System
Lymphopenia
Delayed Hypersensitivity
11 Citations (Scopus)

Epilesional scarification. Preliminary report of a new approach to local immunotherapy with BCG.

Richman, S. P., Mavligit, G. M., Wolk, R., Gutterman, J. U. & Hersh, E. M., Dec 22 1975, In : Journal of the American Medical Association. 234, 12, p. 1233-1235 3 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Immunotherapy
Poisons
Drainage
Fever
36 Citations (Scopus)

Immunology and immunotherapy of human-malignant melanoma: Historic review and perspectives for the future

Gutterman, J. U., Mavligit, G., Reed, R., Richman, S., McBride, C. E. & Hersh, E. M., 1975, In : Seminars in Oncology. 2, 2, p. 155-174 20 p.

Research output: Contribution to journalArticle

Maternally Acquired Immunity
Neoplasm Transplantation
Cell Migration Inhibition
Neoplasm Antibodies
BCG Vaccine

Myron r. karon--a tribute.

Hersh, E. M., Freireich, E. J., Frei, E. & Hammond, D., Aug 1975, In : Cancer Research. 35, 8, p. 2220-2221 2 p.

Research output: Contribution to journalArticle

20th Century History
Molecular Biology
Pediatrics
Myron
10 Citations (Scopus)

Permanent slide preparations of T lymphocyte-sheep red blood cell rosettes

Schafer, L. A., Gutterman, J. U., Mavlight, G. M., Reed, R. C. & Hersh, E. M., 1975, In : Journal of Immunological Methods. 8, 3, p. 241-249 9 p.

Research output: Contribution to journalArticle

Sheep
Erythrocytes
T-Lymphocytes
Rosette Formation
Thymus Gland

Role of BCG immunotherapy in malignant disease

Hersh, E. M., Gutterman, J. U., Mavligit, G. M. & Reed, R. C., 1975, In : Southern Medical Journal. 68, 6, p. 673-675 3 p.

Research output: Contribution to journalArticle

Experimental Neoplasms
BCG Vaccine
Postoperative Care
Neoplasm Antigens
Mycobacterium bovis
3 Citations (Scopus)

Subpopulations of thymus dependent and thymus independent lymphocytes in human gut associated lymphoid tissues

Mavligit, G. M., Jubert, A., Gutterman, J. U., Reed, R. C. & Hersh, E. M., 1975, In : Surgery Gynecology and Obstetrics. 140, 3, p. 397-400 4 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
Thymus Gland
T-Lymphocytes
B-Cell Antigen Receptors
Sheep

Surface proteins of human acute myelogenous leukemia (AML) cells

Cotropia, J. P., Hersh, E. M. & Gutterman, J. U., 1975, In : Federation Proceedings. 34, 3, p. 4664 1 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Membrane Proteins
1974
3 Citations (Scopus)

Blastogenic suppression and alloantibody activity of sera from renal allograft recipients

Johnson, A. H., Rossen, R. D., Hersh, E. M., Farrow, S. S., Butler, W. T. & Suki, W. N., 1974, In : Journal of Clinical Investigation. 53, 1, p. 270-278 9 p.

Research output: Contribution to journalArticle

Isoantibodies
Allografts
Leukocytes
Kidney
Tissue Donors
3 Citations (Scopus)

Cell mediated immunity to plasma cell myeloma: specific inhibition by a serum factor adhering to effector lymphocytes

Mavligit, G. M., Gutterman, J. U., Hersh, E. M. & Alexanian, R., 1974, In : Proceedings of the Society for Experimental Biology and Medicine. 147, 2, p. 537-540 4 p.

Research output: Contribution to journalArticle

Lymphocytes
Multiple Myeloma
Cellular Immunity
Plasmas
Serum
11 Citations (Scopus)
Lymphocytes
Antigens
Erythrocytes
keyhole-limpet hemocyanin
Rosette Formation
117 Citations (Scopus)

CHEMOIMMUNOTHERAPY OF ADULT ACUTE LEUKÆMIA PROLONGATION OF REMISSION IN MYELOBLASTIC LEUKÆMIA WITH B.C.G.

Gutterman, J. U., Rodriguez, V., Mavligit, G., Burgess, M. A., Gehan, E., Hersh, E. M., Mccredie, K. B., Reed, R., Smith, T., Bodey, G. P. & Freireich, E. J., Dec 14 1974, In : The Lancet. 304, 7894, p. 1405-1409 5 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Immunocompetence
Drug Therapy
Immunologic Tests
Cytarabine
137 Citations (Scopus)

Chemoimmunotherapy of disseminated malignant melanoma with dimethyl triazeno imidazole carboxamide and bacillus calmette--guérin.

Gutterman, J. U., Mavligit, G., Gottlieb, J. A., Burgess, M. A., McBride, C. E., Einhorn, L., Freireich, E. J. & Hersh, E. M., Sep 19 1974, In : New England Journal of Medicine. 291, 12, p. 592-597 6 p.

Research output: Contribution to journalArticle

Triazenes
Imidazoles
Procarbazine
Lymphatic Metastasis
Spontaneous Remission

Effect of methylprednisolone on antigen stimulated antibody formation in man

Butler, W. T., Couch, R. B., Hersh, E. M. & Rossen, R. D., 1974, In : Federation Proceedings. 33, 3 I, p. 3063 1 p.

Research output: Contribution to journalArticle

Methylprednisolone
Antibody Formation
Antigens
7 Citations (Scopus)

Focus on cutaneous host defense failure in transplant recipients

Hersh, E. M. & Freireich, E. J., 1974, In : Journal of the American Medical Association. 229, 4, p. 457-458 2 p.

Research output: Contribution to journalArticle

Transplantation Immunology
Herpes Simplex
Homologous Transplantation
Azathioprine
Herpes Zoster