Felicia Goodrum

  • 1741 Citations
  • 21 h-Index
19962020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

Human cytomegalovirus infection suppresses cd34+ progenitor cell engraftment in humanized mice

Crawford, L. B., Tempel, R., Streblow, D. N., Yurochko, A. D., Goodrum, F. D., Nelson, J. A. & Caposio, P., Apr 2020, In : Microorganisms. 8, 4, 525.

Research output: Contribution to journalArticle

Open Access
2019

Alternative promoters drive human cytomegalovirus reactivation from latency

Collins-McMillen, D., Rak, M., Buehler, J. C., Igarashi-Hayes, S., Kamil, J. P., Moorman, N. J. & Goodrum, F., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17492-17497 6 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

HCMV miR-US22 down-regulation of EGR-1 regulates CD34+ hematopoietic progenitor cell proliferation and viral reactivation

Mikell, I., Crawford, L. B., Hancock, M. H., Mitchell, J., Buehler, J., Goodrum, F. & Nelson, J. A., Jan 1 2019, In : PLoS pathogens. 15, 11, e1007854.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency

Buehler, J., Carpenter, E., Zeltzer, S., Igarashi, S., Rak, M., Mikell, I., Nelson, J. A. & Goodrum, F., Jan 1 2019, In : PLoS pathogens. 15, 11, e1008037.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

A single-cell approach to the elusive latent human cytomegalovirus transcriptome

Goodrum, F. & McWeeney, S., May 1 2018, In : mBio. 9, 3, e01001-18.

Research output: Contribution to journalArticle

2 Scopus citations

Human cytomegalovirus UL135 interacts with host adaptor proteins to regulate epidermal growth factor receptor and reactivation from latency

Rak, M. A., Buehler, J., Zeltzer, S., Reitsma, J., Molina, B., Terhune, S. & Goodrum, F., Oct 1 2018, In : Journal of Virology. 92, 20, e00919.

Research output: Contribution to journalArticle

6 Scopus citations

Virus control of trafficking from sorting endosomes

Zeltzer, S., Zeltzer, C. A., Igarashi, S., Wilson, J., Donaldson, J. G. & Goodrum, F., Jul 1 2018, In : mBio. 9, 4, e00683-18.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Human cytomegalovirus requires epidermal growth factor receptor signaling to enter and initiate the early steps in the establishment of latency in CD34+ human progenitor cells

Kim, J. H., Collins-McMillen, D., Buehler, J. C., Goodrum, F. & Yurochko, A. D., 2017, In : Journal of Virology. 91, 5, e01206-16.

Research output: Contribution to journalArticle

32 Scopus citations

Recent advances in CMV tropism, latency, and diagnosis during aging

Leng, S. X., Kamil, J., Purdy, J. G., Lemmermann, N. A., Reddehase, M. J. & Goodrum, F., Jun 1 2017, In : GeroScience. 39, 3, p. 251-259 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection

Gordon, C. L., Miron, M., Thome, J. J. C., Matsuoka, N., Weiner, J., Rak, M. A., Igarashi, S., Granot, T., Lerner, H., Goodrum, F. & Farber, D. L., Jan 27 2017, In : Journal of Experimental Medicine. 214, 3, p. 651-667 17 p.

Research output: Contribution to journalArticle

46 Scopus citations
41 Scopus citations
2016

Complex interplay of the UL136 isoforms balances cytomegalovirus replication and Latency

Caviness, K., Bughio, F., Crawford, L. B., Streblow, D. N., Nelson, J. A., Caposio, P. & Goodrum, F., Mar 1 2016, In : mBio. 7, 2, e01986-15.

Research output: Contribution to journalArticle

22 Scopus citations

Long and short isoforms of the human cytomegalovirus UL138 protein silence IE transcription and promote latency

Lee, S. H., Caviness, K., Albright, E. R., Lee, J. H., Gelbmann, C. B., Rak, M., Goodrum, F. & Kalejta, R. F., Jan 1 2016, In : Journal of virology. 90, 20, p. 9483-9494 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication

Buehler, J., Zeltzer, S., Reitsma, J., Petrucelli, A., Umashankar, M., Rak, M., Zagallo, P., Schroeder, J., Terhune, S. & Goodrum, F., May 2016, In : PLoS pathogens. 12, 5, e1005655.

Research output: Contribution to journalArticle

30 Scopus citations
2015

Human cytomegalovirus UL135 and UL136 genes are required for postentry tropism in endothelial cells

Bughio, F., Umashankar, M., Wilson, J. & Goodrum, F., Jan 1 2015, In : Journal of virology. 89, 13, p. 6536-6550 15 p.

Research output: Contribution to journalArticle

14 Scopus citations
2014

An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle

Li, G., Rak, M., Nguyen, C. C., Umashankar, M., Goodrum, F. D. & Kamil, J. P., Jun 2014, In : Journal of virology. 88, 11, p. 6047-6060 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection

Umashankar, M., Rak, M., Bughio, F., Zagallo, P., Caviness, K. & Goodrum, F. D., Jun 2014, In : Journal of virology. 88, 11, p. 5987-6002 16 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hematopoietic long-term culture (hLTC) for human cytomegalovirus latency and reactivation

Umashankar, M. & Goodrum, F., Jan 1 2014, In : Methods in Molecular Biology. 1119, p. 99-112 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

New advances in CMV and immunosenescence

Sansoni, P., Vescovini, R., Fagnoni, F. F., Akbar, A., Arens, R., Chiu, Y. L., Čičin-Šain, L., Dechanet-Merville, J., Derhovanessian, E., Ferrando-Martinez, S., Franceschi, C., Frasca, D., Fulöp, T., Furman, D., Gkrania-Klotsas, E., Goodrum, F., Grubeck-Loebenstein, B., Hurme, M., Kern, F., Lilleri, D. & 20 others, López-Botet, M., Maier, A. B., Marandu, T., Marchant, A., Matheï, C., Moss, P., Muntasell, A., Remmerswaal, E. B. M., Riddell, N. E., Rothe, K., Sauce, D., Shin, E. C., Simanek, A. M., Smithey, M. J., Söderberg-Nauclér, C., Solana, R., Thomas, P. G., Van Lier, R., Pawelec, G. & Nikolich-Zugich, J., Jul 2014, In : Experimental Gerontology. 55, p. 54-62 9 p.

Research output: Contribution to journalArticle

83 Scopus citations
2013

Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein

Zalckvar, E., Paulus, C., Tillo, D., Asbach-Nitzsche, A., Lubling, Y., Winterling, C., Strieder, N., Mücke, K., Goodrum, F., Segal, E. & Nevels, M., Aug 6 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 32, p. 13126-13131 6 p.

Research output: Contribution to journalArticle

18 Scopus citations
2012

Interactions between proteins encoded within the human cytomegalovirus UL133-UL138 locus

Petrucelli, A., Umashankar, M., Zagallo, P., Rak, M. & Goodrum, F., Aug 1 2012, In : Journal of virology. 86, 16, p. 8653-8662 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2011

A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection

Umashankar, M., Petrucelli, A., Cicchini, L., Caposio, P., Kreklywich, C. N., Rak, M., Bughio, F., Goldman, D. C., Hamlin, K. L., Nelson, J. A., Fleming, W. H., Streblow, D. N. & Goodrum, F., Dec 1 2011, In : PLoS pathogens. 7, 12, e1002444.

Research output: Contribution to journalArticle

77 Scopus citations
2010

CD8+ T-cell recognition of human cytomegalovirus latency-associated determinant pUL138

Tey, S. K., Goodrum, F. & Khanna, R., Aug 1 2010, In : Journal of General Virology. 91, 8, p. 2040-2048 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Stress-inducible alternative translation initiation of human cytomegalovirus latency protein pUL138

Grainger, L., Cicchini, L., Rak, M., Petrucelli, A., Fitzgerald, K. D., Semler, B. L. & Goodrum, F., Sep 2010, In : Journal of virology. 84, 18, p. 9472-9486 15 p.

Research output: Contribution to journalArticle

47 Scopus citations
2009

Characterization of a novel Golgi apparatus-localized latency determinant encoded by human cytomegalovirus

Petrucelli, A., Rak, M., Grainger, L. & Goodrum, F., Jun 1 2009, In : Journal of virology. 83, 11, p. 5615-5629 15 p.

Research output: Contribution to journalArticle

75 Scopus citations

E4orf1 limits the oncolytic potential of the E1B-55K deletion mutant adenovirus

Thomas, M. A., Broughton, R. S., Goodrum, F. D. & Ornelles, D. A., Mar 1 2009, In : Journal of virology. 83, 6, p. 2406-2416 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
2007

Analysis of adenovirus infections in synchronized cells.

Ornelles, D. A., Broughton-Shepard, R. N. & Goodrum, F. D., 2007, In : Methods in molecular medicine. 131, p. 83-101 19 p.

Research output: Contribution to journalArticle

3 Scopus citations

Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro

Goodrum, F., Reeves, M., Sinclair, J., High, K. & Shenk, T., Aug 1 2007, In : Blood. 110, 3, p. 937-945 9 p.

Research output: Contribution to journalArticle

161 Scopus citations
2004

Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations

Goodrum, F., Jordan, C. T., Terhune, S. S., High, K. & Shenk, T., Aug 1 2004, In : Blood. 104, 3, p. 687-695 9 p.

Research output: Contribution to journalArticle

105 Scopus citations
2002
182 Scopus citations
1999

Roles for the E4 orf6, orf3, and E1B 55-kilodalton proteins in cell cycle-independent adenovirus replication

Goodrum, F. D. & Ornelles, D. A., Aug 23 1999, In : Journal of virology. 73, 9, p. 7474-7488 15 p.

Research output: Contribution to journalArticle

52 Scopus citations
1998

p53 Status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection

Goodrum, F. D. & Ornelles, D. A., Dec 1 1998, In : Journal of virology. 72, 12, p. 9479-9490 12 p.

Research output: Contribution to journalArticle

240 Scopus citations
1997

The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle

Goodrum, F. D. & Ornelles, D. A., Jan 1 1997, In : Journal of virology. 71, 1, p. 548-561 14 p.

Research output: Contribution to journalArticle

105 Scopus citations
1996

Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells

Goodrum, F. D., Shenk, T. & Ornelles, D. A., Sep 1 1996, In : Journal of virology. 70, 9, p. 6323-6335 13 p.

Research output: Contribution to journalArticle

79 Scopus citations