Projects per year
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- 6 Similar Profiles
delta Opioid Receptor
Medicine & Life Sciences
Opioid Analgesics
Medicine & Life Sciences
Morphine
Medicine & Life Sciences
mu Opioid Receptor
Medicine & Life Sciences
Opioid Receptors
Medicine & Life Sciences
Pain
Medicine & Life Sciences
Enkephalins
Medicine & Life Sciences
Neuralgia
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1984 2021
Cortical opioid dysfunction in chronic pain
4/15/16 → 1/31/21
Project: Research project › Research Project
Chronic Pain
Opioid Analgesics
Pain
Dopamine
Analgesics
Long-Acting Peripherally-Restricted Peptidic Kappa Opioid Receptor Agonists for Pain
8/1/16 → 7/31/17
Project: Research project › Small Business Innovation Research Grants (SBIR) - Phase I
kappa Opioid Receptor
Pain
mu Opioid Receptor
Opioid Analgesics
Analgesics
Brain reward circuits and relief of ongoing pain
6/1/13 → 2/28/18
Project: Research project › Research Project
Reward
Pain
Brain
Nucleus Accumbens
Ventral Tegmental Area
High School Student NeuroResearch Program (HSNRP)
8/1/11 → 6/30/16
Project: Research project › Education Projects
Students
Vulnerable Populations
Nervous System Diseases
Research
Stroke
Research Output 1980 2018
Nanoparticulate peptide delivery exclusively to the brain produces tolerance free analgesia
Godfrey, L., Iannitelli, A., Garrett, N. L., Moger, J., Imbert, I., King, T., Porreca, F., Soundararajan, R., Lalatsa, A., Schätzlein, A. G. & Uchegbu, I. F. Jan 28 2018 In : Journal of Controlled Release. 270, p. 135-144 10 p.Research output: Contribution to journal › Article
Nanoparticles
Analgesia
Peptides
Enkephalins
Brain
1
Citations
Activation of dura-sensitive trigeminal neurons and increased c-Fos protein induced by morphine withdrawal in the rostral ventromedial medulla
Hitomi, S., Kross, K., Kurose, M., Porreca, F. & Meng, I. D. Apr 1 2017 In : Cephalalgia. 37, 5, p. 407-417 11 p.Research output: Contribution to journal › Article
Proto-Oncogene Proteins c-fos
Morphine
Neurons
Headache
Microinjections
1
Citations
Anatomy and immunochemical characterization of the non-arterial peptidergic diffuse dural innervation of the rat and Rhesus monkey: Implications for functional regulation and treatment in migraine
Rice, F. L., Xie, J. Y., Albrecht, P. J., Acker, E., Bourgeois, J., Navratilova, E., Dodick, D. W. & Porreca, F. Dec 1 2017 In : Cephalalgia. 37, 14, p. 1350-1372 23 p.Research output: Contribution to journal › Article
Adrenergic Fibers
Dura Mater
Unmyelinated Nerve Fibers
Macaca mulatta
Migraine Disorders
3
Citations
CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide
Moutal, A., Yang, X., Li, W., Gilbraith, K. B., Luo, S., Cai, S., François-Moutal, L., Chew, L. A., Yeon, S. K., Bellampalli, S. S., Qu, C., Xie, J. Y., Ibrahim, M. M., Khanna, M., Park, K. D., Porreca, F. & Khanna, R. Jan 1 2017 In : Pain. 158, 12, p. 2301-2319 19 p.Research output: Contribution to journal › Article
Clustered Regularly Interspaced Short Palindromic Repeats
Neurofibromatosis 1 Genes
Neurofibromatosis 1
Neurofibromin 1
Pain
5
Citations
Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention
Xie, J. Y., De Felice, M., Kopruszinski, C. M., Eyde, N., Lavigne, J., Remeniuk, B., Hernandez, P., Yue, X., Goshima, N., Ossipov, M., King, T., Streicher, J. M., Navratilova, E., Dodick, D., Rosen, H., Roberts, E. & Porreca, F. Jul 1 2017 In : Cephalalgia. 37, 8, p. 780-794 15 p.Research output: Contribution to journal › Article
kappa Opioid Receptor
Narcotic Antagonists
Migraine Disorders
Hyperalgesia
Secondary Headache Disorders