Frank Porreca

  • 29164 Citations
  • 94 h-Index
1980 …2021
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
delta Opioid Receptor Medicine & Life Sciences
Opioid Analgesics Medicine & Life Sciences
Morphine Medicine & Life Sciences
Opioid Receptors Medicine & Life Sciences
mu Opioid Receptor Medicine & Life Sciences
Pain Medicine & Life Sciences
Neuralgia Medicine & Life Sciences
Hyperalgesia Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1984 2021

Cortical opioid dysfunction in chronic pain

Porreca, F.

National Institutes of Health

4/15/161/31/21

Project: Research projectResearch Project

Chronic Pain
Opioid Analgesics
Pain
Dopamine
Analgesics

Long-Acting Peripherally-Restricted Peptidic Kappa Opioid Receptor Agonists for Pain

Porreca, F.

National Institutes of Health

8/1/167/31/17

Project: Research projectSmall Business Innovation Research Grants (SBIR) - Phase I

kappa Opioid Receptor
Pain
mu Opioid Receptor
Opioid Analgesics
Analgesics

Brain reward circuits and relief of ongoing pain

Porreca, F.

National Institutes of Health

6/1/132/28/18

Project: Research projectResearch Project

Reward
Pain
Brain
Nucleus Accumbens
Ventral Tegmental Area

High School Student NeuroResearch Program (HSNRP)

Witte, M. H. & Porreca, F.

National Institutes of Health

8/1/116/30/16

Project: Research projectEducation Projects

Students
Vulnerable Populations
Nervous System Diseases
Research
Stroke

Research Output 1980 2018

3 Citations

Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer

Watanabe, M., Narita, M., Hamada, Y., Yamashita, A., Tamura, H., Ikegami, D., Kondo, T., Shinzato, T., Shimizu, T., Fukuchi, Y., Muto, A., Okano, H., Yamanaka, A., Tawfik, V. L., Kuzumaki, N., Navratilova, E., Porreca, F. & Narita, M., Jan 1 2018, In : Molecular Pain. 14

Research output: Contribution to journalArticle

Bone Neoplasms
Ventral Tegmental Area
Dopaminergic Neurons
Hyperalgesia
Nucleus Accumbens

Cyclic biphalin analogues with a novel linker lead to potent agonist activities at mu, delta, and kappa opioid receptors

Remesic, M., Macedonio, G., Mollica, A., Porreca, F., Hruby, V. J. & Lee, Y. S., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

kappa Opioid Receptor
delta Opioid Receptor
mu Opioid Receptor
hydrazine
Opioid Receptors

Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain

Remeniuk, B., King, T., Sukhtankar, D., Nippert, A., Li, N., Li, F., Cheng, K., Rice, K. C. & Porreca, F., Apr 1 2018, In : Pain. 159, 4, p. 684-698 15 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Interleukin-6
Bone Remodeling
Pain
Neoplasms
1 Citations

Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system

Watanabe, M., Sugiura, Y., Sugiyama, E., Narita, M., Navratilova, E., Kondo, T., Uchiyama, N., Yamanaka, A., Kuzumaki, N., Porreca, F. & Narita, M., Jan 1 2018, In : Molecular Pain. 14

Research output: Contribution to journalArticle

Microdialysis
Nucleus Accumbens
Mass Spectrometry
Pain
Neurotransmitter Agents
3 Citations

Kappa Opioid Receptor Distribution and Function in Primary Afferents

Snyder, L. M., Chiang, M. C., Loeza-Alcocer, E., Omori, Y., Hachisuka, J., Sheahan, T. D., Gale, J. R., Adelman, P. C., Sypek, E. I., Fulton, S. A., Friedman, R. L., Wright, M. C., Duque, M. G., Lee, Y. S., Hu, Z., Huang, H., Cai, X., Meerschaert, K. A., Nagarajan, V., Hirai, T. & 7 othersScherrer, G., Kaplan, D. H., Porreca, F., Davis, B. M., Gold, M. S., Koerber, H. R. & Ross, S. E., Sep 19 2018, In : Neuron. 99, 6, p. 1274-1288.e6

Research output: Contribution to journalArticle

kappa Opioid Receptor
Sensory Receptor Cells
Neurogenic Inflammation
Nociceptors
Mechanoreceptors