• 3676 Citations
  • 31 h-Index
1994 …2020

Research output per year

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Research Output

2009

Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1

Cabello, C. M., Bair, W. B., Bause, A. S. & Wondrak, G. T., Aug 15 2009, In : Biochemical Pharmacology. 78, 4, p. 344-354 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

More than skin deep: The human skin tissue equivalent as an advanced drug discovery tool

Bause, A. S., Lamore, S. D. & Wondrak, G. T., Dec 1 2009, In : Frontiers in Drug Design and Discovery. 4, 1, p. 135-161 27 p.

Research output: Contribution to journalArticle

3 Scopus citations

Redox-directed cancer therapeutics: Molecular mechanisms and opportunities

Wondrak, G. T., Dec 1 2009, In : Antioxidants and Redox Signaling. 11, 12, p. 3013-3069 57 p.

Research output: Contribution to journalReview article

327 Scopus citations

The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth

Cabello, C. M., Bair, W. B., Lamore, S. D., Ley, S., Bause, A. S., Azimian, S. & Wondrak, G. T., Jan 15 2009, In : Free Radical Biology and Medicine. 46, 2, p. 220-231 12 p.

Research output: Contribution to journalArticle

108 Scopus citations

The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A (p21) upregulation in human cancer cell lines

Cabello, C. M., Bair, W. B., Ley, S., Lamore, S. D., Azimian, S. & Wondrak, G. T., Apr 1 2009, In : Biochemical Pharmacology. 77, 7, p. 1125-1138 14 p.

Research output: Contribution to journalArticle

42 Scopus citations
2008

Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress

Wondrak, G. T., Cabello, C. M., Villeneuve, N. F., Zhang, S., Ley, S., Li, Y., Sun, Z. & Zhang, D. D., Aug 15 2008, In : Free Radical Biology and Medicine. 45, 4, p. 385-395 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

Wang, X. J., Sun, Z., Villeneuve, N. F., Zhang, S., Zhao, F., Li, Y., Chen, W., Yi, X., Zheng, W., Wondrak, G. T., Wong, P. K. & Zhang, D. D., Jun 2008, In : Carcinogenesis. 29, 6, p. 1235-1243 9 p.

Research output: Contribution to journalArticle

479 Scopus citations

Reactivity-based drug discovery using vitamin B6-derived pharmacophores

Wondrak, G. T., 2008, In : Mini-Reviews in Medicinal Chemistry. 8, 5, p. 519-528 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2007

Experimental therapeutics: Targeting the redox Achilles heel of cancer

Cabello, C. M., Bair, W. B. & Wondrak, G. T., Dec 12 2007, In : Current Opinion in Investigational Drugs. 8, 12, p. 1022-1037 16 p.

Research output: Contribution to journalReview article

96 Scopus citations

Let the sun shine in: Mechanisms and potential for therapeutics in skin photodamage

Wondrak, G. T., May 2007, In : Current Opinion in Investigational Drugs. 8, 5, p. 390-400 11 p.

Research output: Contribution to journalReview article

38 Scopus citations
51 Scopus citations
2006

Antimelanoma activity of apoptogenic carbonyl scavengers

Wondrak, G. T., Jacobson, M. K. & Jacobson, E. L., Feb 2006, In : Journal of Pharmacology and Experimental Therapeutics. 316, 2, p. 805-814 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Endogenous UVA-photosensitizers: Mediators of skin photodamage and novel targets for skin photoprotection

Wondrak, G. T., Jacobson, M. K. & Jacobson, E. L., Feb 7 2006, In : Photochemical and Photobiological Sciences. 5, 2, p. 215-237 23 p.

Research output: Contribution to journalArticle

265 Scopus citations
2005

Developing topical prodrugs for skin cancer prevention

Jacobson, E. L., Kim, H., Kim, M., Wondrak, G. T. & Jacobson, M. K., Dec 1 2005, Fundamentals of Cancer Prevention. Springer Berlin Heidelberg, p. 215-237 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Developing topical prodrugs for skin cancer prevention

Jacobson, E. L., Kim, H., Kim, M., Wondrak, G. T. & Jacobson, M. K., Dec 1 2005, Fundamentals of Cancer Prevention. Springer Berlin Heidelberg, p. 139-160 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Identification of quenchers of photoexcited states as novel agents for skin photoprotection

Wondrak, G. T., Jacobson, M. K. & Jacobson, E. L., Feb 2005, In : Journal of Pharmacology and Experimental Therapeutics. 312, 2, p. 482-491 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
2004

3-Hydroxypyridine chromophores are endogenous sensitizers of photooxidative stress in human skin cells

Wondrak, G. T., Roberts, M. J., Jacobson, M. K. & Jacobson, E. L., Jul 16 2004, In : Journal of Biological Chemistry. 279, 29, p. 30009-30020 12 p.

Research output: Contribution to journalArticle

55 Scopus citations
2003

DNA damage by carbonyl stress in human skin cells

Roberts, M. J., Wondrak, G. T., Laurean, D. C., Jacobson, M. K. & Jacobson, E. L., Jan 28 2003, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 522, 1-2, p. 45-56 12 p.

Research output: Contribution to journalArticle

91 Scopus citations

Proteins of the extracellular matrix are sensitizers of photo-oxidative stress in human skin cells

Wondrak, G. T., Roberts, M. J., Cervantes-Laurean, D., Jacobson, M. K. & Jacobson, E. L., Sep 1 2003, In : Journal of Investigative Dermatology. 121, 3, p. 578-586 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
2002

Identification of α-dicarbonyl scavengers for cellular protection against carbonyl stress

Wondrak, G. T., Cervantes-Laurean, D., Roberts, M. J., Qasem, J. G., Kim, M., Jacobson, E. L. & Jacobson, M. K., Feb 1 2002, In : Biochemical Pharmacology. 63, 3, p. 361-373 13 p.

Research output: Contribution to journalArticle

94 Scopus citations

Photosensitization of DNA damage by glycated proteins

Wondrak, G. T., Jacobson, E. L. & Jacobson, M. K., May 17 2002, In : Photochemical and Photobiological Sciences. 1, 5, p. 355-363 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Photosensitized growth inhibition of cultured human skin cells: Mechanism and suppression of oxidative stress from solar irradiation of glycated proteins

Wondrak, G. T., Roberts, M. J., Jacobson, M. K. & Jacobson, E. L., Jan 1 2002, In : Journal of Investigative Dermatology. 119, 2, p. 489-498 10 p.

Research output: Contribution to journalArticle

53 Scopus citations
2001

Chapter 34 Metabolic effects of solar radiation and enhancers of energy metabolism

Jacobson, E. L., Giacomoni, P. U., Roberts, M. J., Wondrak, G. T. & Jacobson, M. K., 2001, Comprehensive Series in Photosciences. C ed. Elsevier, p. 677-690 14 p. (Comprehensive Series in Photosciences; vol. 3, no. C).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Optimizing the energy status of skin cells during solar radiation

Jacobson, E. L., Giacomoni, P. U., Roberts, M. J., Wondrak, G. T. & Jacobson, M. K., Oct 1 2001, In : Journal of Photochemistry and Photobiology B: Biology. 63, 1-3, p. 141-147 7 p.

Research output: Contribution to journalArticle

59 Scopus citations
2000

Formation of a protein-bound pyrazinium free radical cation during glycation of histone H1

Wondrak, G. T., Varadarajan, S., Butterfield, D. A. & Jacobson, M. K., Sep 15 2000, In : Free Radical Biology and Medicine. 29, 6, p. 557-567 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Histone carbonylation in vivo and in vitro

Wondrak, G. T., Cervantes-Laurean, D., Jacobson, E. L. & Jacobson, M. K., Nov 1 2000, In : Biochemical Journal. 351, 3, p. 769-777 9 p.

Research output: Contribution to journalArticle

74 Scopus citations
1998

Identification of Maillard Type Polymers with Antioxidative Activity

Tressll, R., Wondrak, G., Kersten, E., Kriiger, R. P. & Rewicki, D., Dec 1 1998, In : ACS Symposium Series. 702, p. 209-220 12 p.

Research output: Contribution to journalArticle

Pentoses and Hexoses as Sources of New Melanoidin-like Maillard Polymers

Tressl, R., Wondrak, G. T., Garbe, L. A., Krüger, R. P. & Rewicki, D., May 1998, In : Journal of Agricultural and Food Chemistry. 46, 5, p. 1765-1776 12 p.

Research output: Contribution to journalArticle

102 Scopus citations
1997

Maillard Reaction of Free and Nucleic Acid-Bound 2-Deoxy-D-ribose and D-Ribose with ω-Amino Acids

Wondrak, G. T., Tressl, R. & Rewicki, D., Feb 1 1997, In : Journal of Agricultural and Food Chemistry. 45, 2, p. 321-327 7 p.

Research output: Contribution to journalArticle

17 Scopus citations
1995

Light from Maillard reaction: photon counting, emission spectrum, photography and visual perception.

Wondrak, G., Pier, T. & Tressl, R., Jan 1 1995, In : Journal of bioluminescence and chemiluminescence. 10, 5, p. 277-284 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
1994

Structure and Potential Cross‐linking Reactivity of a New Pentose-Specific Maillard Product

Tressl, R., Wondrak, G., Kersten, E. & Rewicki, D., Dec 1 1994, In : Journal of Agricultural and Food Chemistry. 42, 12, p. 2692-2697 6 p.

Research output: Contribution to journalArticle

7 Scopus citations