George S Watts

  • 1512 Citations
  • 22 h-Index
1978 …2021
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1995 2017

  • 1512 Citations
  • 22 h-Index
  • 31 Article
Filter
Article
2017
2 Citations (Scopus)

16S rRNA gene sequencing on a benchtop sequencer: accuracy for identification of clinically important bacteria

Watts, G. S., Youens-Clark, K., Slepian, M. J., Wolk, D., Oshiro, M. M., Metzger, G. S., Dhingra, D., Cranmer, L. D. & Hurwitz, B. L., Dec 1 2017, In : Journal of Applied Microbiology. 123, 6, p. 1584-1596 13 p.

Research output: Contribution to journalArticle

rRNA Genes
Bacteria
Ions
Databases
Metagenomics
2015
1 Citation (Scopus)

Characterization of a novel radiation-induced sarcoma cell line

Lang, J., Zhu, W., Nokes, B., Sheth, G., Novak, P., Fuchs, L., Watts, G. S., Futscher, B. W., Mineyev, N., Ring, A., Lebeau, L., Nagle, R. B. & Cranmer, L. D., May 1 2015, In : Journal of Surgical Oncology. 111, 6, p. 669-682 14 p.

Research output: Contribution to journalArticle

Sarcoma
Radiation
Cell Line
Neoplasms
SCID Mice
7 Citations (Scopus)
Integrins
Non-Small Cell Lung Carcinoma
Up-Regulation
Lung Neoplasms
Neoplasms
8 Citations (Scopus)

Innovative qPCR using interfacial effects to enable low threshold cycle detection and inhibition relief

Harshman, D. K., Rao, B. M., Mclain, J. E. T., Watts, G. S. & Yoon, J-Y., Sep 1 2015, In : Science advances. 1, 8, e1400061.

Research output: Contribution to journalArticle

Real-Time Polymerase Chain Reaction
Point-of-Care Systems
Optical Devices
Access to Information
Surface Tension
2014
8 Citations (Scopus)

Environmental arsenic exposure and microbiota in induced sputum

White, A. G., Watts, G. S., Lu, Z., Meza-Montenegro, M. M., Lutz, E. A., Harber, P. I. & Burgess, J. L., Feb 21 2014, In : International Journal of Environmental Research and Public Health. 11, 2, p. 2299-2313 15 p.

Research output: Contribution to journalArticle

Microbiota
Environmental Exposure
Arsenic
Sputum
Neisseriaceae
32 Citations (Scopus)

Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations

Garbe, J. C., Vrba, L., Sputova, K., Fuchs, L., Novak, P., Brothman, A. R., Jackson, M., Chin, K., La Barge, M. A., Watts, G. S., Futscher, B. W. & Stampfer, M. R., Nov 1 2014, In : Cell Cycle. 13, 21, p. 3423-3435 13 p.

Research output: Contribution to journalArticle

Breast
Epithelial Cells
Telomerase
Telomere Shortening
Carcinoma
101 Citations (Scopus)

Three-dimensional printing surgical instruments: Are we there yet?

Rankin, T. M., Giovinco, N. A., Cucher, D. J., Watts, G. S., Hurwitz, B. L. & Armstrong, D. G., Jun 15 2014, In : Journal of Surgical Research. 189, 2, p. 193-197 5 p.

Research output: Contribution to journalArticle

Surgical Instruments
Operating Rooms
Costs and Cost Analysis
Tissue Scaffolds
Polymerase Chain Reaction
2013
8 Citations (Scopus)

Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes

Cyr, A. R., Brown, K. E., McCormick, M. L., Coleman, M. C., Case, A. J., Watts, G. S., Futscher, B. W., Spitz, D. R. & Domann, F. E., 2013, In : Redox Biology. 1, 1, p. 172-177 6 p.

Research output: Contribution to journalArticle

Liver
Superoxide Dismutase
Hepatocytes
Maintenance
Mitochondrial DNA
2012
28 Citations (Scopus)

The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: The role of deoxycholic acid

Roesly, H. B., Khan, M. R., Chen, H. D. R., Hill, K. A., Narendran, N., Watts, G. S., Chen, X. & Dvorak, K., Apr 15 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 8

Research output: Contribution to journalArticle

Deoxycholic Acid
Barrett Esophagus
Adenocarcinoma
Autophagy
Bile Acids and Salts
18 Citations (Scopus)

The matrix protein CCN1/CYR61 is required for αVβ5-mediated cancer cell migration

Jandova, J., Beyer, T. E., Meuillet, E. & Watts, G. S., Dec 2012, In : Cell Biochemistry and Function. 30, 8, p. 687-695 9 p.

Research output: Contribution to journalArticle

Cysteine-Rich Protein 61
Integrins
Cell Movement
Cells
Tumors
2010
35 Citations (Scopus)

A novel mechanism of acid and bile acid-induced DNA damage involving Na+/H+ exchanger: Implication for Barrett's oesophagus

Goldman, A., Shahidullah, M. ., Goldman, D., Khailova, L., Watts, G. S., Delamere, N. A. & Dvorak, K., Dec 2010, In : Gut. 59, 12, p. 1606-1616 11 p.

Research output: Contribution to journalArticle

Sodium-Hydrogen Antiporter
Barrett Esophagus
Bile Acids and Salts
DNA Damage
Acids
2009
22 Citations (Scopus)

Expression of bile acid transporting proteins in Barrett's esophagus and esophageal adenocarcinoma

Dvorak, K., Watts, G. S., Ramsey, L., Holubec, H., Payne, C. M., Bernstein, C., Jenkins, G. J., Sampliner, R. E., Rama Rao, A. P., Garewal, H. S. & Bernstein, H., Feb 2009, In : American Journal of Gastroenterology. 104, 2, p. 302-309 8 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Bile Acids and Salts
Adenocarcinoma
Epithelium
Proteins
2008
96 Citations (Scopus)

Agglomerative epigenetic aberrations are a common event in human breast cancer

Novak, P., Jensen, T., Oshiro, M. M., Watts, G. S., Kim, C. J. & Futscher, B. W., Oct 15 2008, In : Cancer Research. 68, 20, p. 8616-8625 10 p.

Research output: Contribution to journalArticle

Epigenomics
Breast Neoplasms
DNA Methylation
Multigene Family
Genomic Segmental Duplications
44 Citations (Scopus)

Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells

Junk, D. J., Vrba, L., Watts, G. S., Oshiro, M. M., Martinez, J. D. & Futscher, B. W., May 2008, In : Neoplasia. 10, 5, p. 450-461 12 p.

Research output: Contribution to journalArticle

Breast
Epithelial Cells
Carcinogenesis
Phenotype
Choristoma
2007
47 Citations (Scopus)

Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma

Watts, G. S., Tran, N. L., Berens, M. E., Bhattacharyya, A. K., Nelson, M. A., Montgomery, E. A. & Sampliner, R. E., Nov 15 2007, In : International Journal of Cancer. 121, 10, p. 2132-2139 8 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Barrett Esophagus
imidazole mustard
Cell Line
Therapeutics
37 Citations (Scopus)

Large-scale regulatory network analysis from microarray data: modified Bayesian network learning and association rule mining

Huang, Z., Li, J., Su, H., Watts, G. S. & Chen, H., Aug 2007, In : Decision Support Systems. 43, 4, p. 1207-1225 19 p.

Research output: Contribution to journalArticle

Association Learning
Association rules
Bayesian networks
Microarray Analysis
Microarrays
31 Citations (Scopus)

Profiling of selenomethionine responsive genes in colon cancer by microarray analysis

Goulet, A. C., Watts, G. S., Lord, J. L. & Nelson, M. A., Apr 2007, In : Cancer Biology and Therapy. 6, 4, p. 494-503 10 p.

Research output: Contribution to journalArticle

Selenomethionine
Microarray Analysis
Colonic Neoplasms
Genes
Selenium
2006
22 Citations (Scopus)

AP-2α and AP-2γ are transcriptional targets of p53 in human breast carcinoma cells

Li, H., Watts, G. S., Oshiro, M. M., Futscher, B. W. & Domann, F. E., Aug 31 2006, In : Oncogene. 25, 39, p. 5405-5415 11 p.

Research output: Contribution to journalArticle

Transcription Factor AP-2
Breast Neoplasms
Chromatin
GC Rich Sequence
Chromatin Immunoprecipitation
89 Citations (Scopus)

Epigenetic inactivation of the HOXA gene cluster in breast cancer

Novak, P., Jensen, T., Oshiro, M. M., Wozniak, R. J., Nouzova, M., Watts, G. S., Klimecki, W., Kim, C. & Futscher, B. W., Nov 15 2006, In : Cancer Research. 66, 22, p. 10664-10670 7 p.

Research output: Contribution to journalArticle

Multigene Family
Epigenomics
Breast Neoplasms
DNA Methylation
Histone Code
4 Citations (Scopus)
Pharmacogenetics
Polyamines
DNA Methylation
Colon
Adenocarcinoma
2004
118 Citations (Scopus)

Performance evaluation of commercial short-oligonucleotide microarrays and the impact of noise in making cross-platform correlations

Shippy, R., Sendera, T. J., Lockner, R., Palaniappan, C., Kaysser-Kranich, T., Watts, G. S. & Alsobrook, J., Sep 2 2004, In : BMC Genomics. 5, 61.

Research output: Contribution to journalArticle

Oligonucleotide Array Sequence Analysis
Noise
Overlapping Genes
Genes
Guidelines
35 Citations (Scopus)

The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells

Watts, G. S., Oshiro, M. M., Junk, D. J., Wozniak, R. J., Watterson, S. J., Domann, F. E. & Futscher, B. W., May 2004, In : Neoplasia. 6, 3, p. 187-194 8 p.

Research output: Contribution to journalArticle

Acetyltransferases
p53 Genes
Breast Neoplasms
Tumor Cell Line
Doxorubicin
38 Citations (Scopus)

The Chemopreventive Agent α-Difluoromethylornithine Blocks Ki-ras-Dependent Tumor Formation and Specific Gene Expression in Caco-2 Cells

Ignatenko, N., Zhang, H., Watts, G. S., Skovan, B. A., Stringer, D. E. & Gerner, E. W., Apr 2004, In : Molecular Carcinogenesis. 39, 4, p. 221-233 13 p.

Research output: Contribution to journalArticle

Eflornithine
Caco-2 Cells
Gene Expression
Integrin alpha1
Neoplasms
2003
49 Citations (Scopus)

Low-level arsenite induced gene expression in HEK293 cells

Zheng, X. H., Watts, G. S., Vaught, S. & Gandolfi, A. J., May 1 2003, In : Toxicology. 187, 1, p. 39-48 10 p.

Research output: Contribution to journalArticle

HEK293 Cells
Gene expression
Genes
Gene Expression
Arsenic
76 Citations (Scopus)

Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression

Oshiro, M. M., Watts, G. S., Wozniak, R. J., Junk, D. J., Munoz-Rodriguez, J. L., Domann, F. E. & Futscher, B. W., Jun 5 2003, In : Oncogene. 22, 23, p. 3624-3634 11 p.

Research output: Contribution to journalArticle

Cytosine
Methylation
Gene Expression
Desmocollins
DNA Methylation
2002
69 Citations (Scopus)

Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate

Crowley-Weber, C. L., Payne, C. M., Gleason-Guzman, M., Watts, G. S., Futscher, B. W., Waltmire, C. N., Crowley, C., Dvorakova, K., Bernstein, C., Craven, M., Garewal, H. & Bernstein, H., Dec 1 2002, In : Carcinogenesis. 23, 12, p. 2063-2080 18 p.

Research output: Contribution to journalArticle

HCT116 Cells
Deoxycholic Acid
Carcinogens
Apoptosis
Cell Line
2001
63 Citations (Scopus)

cDNA microarray analysis of multidrug resistance: Doxorubicin selection produces multiple defects in apoptosis signaling pathways

Watts, G. S., Futscher, B. W., Isett, R., Gleason-Guzman, M., Kunkel, M. W. & Salmon, S. E., 2001, In : Journal of Pharmacology and Experimental Therapeutics. 299, 2, p. 434-441 8 p.

Research output: Contribution to journalArticle

Multiple Drug Resistance
Microarray Analysis
Oligonucleotide Array Sequence Analysis
Doxorubicin
Apoptosis
151 Citations (Scopus)

Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: A cDNA microarray analysis

Mariani, L., Beaudry, C., McDonough, W. S., Hoelzinger, D. B., Demuth, T., Ross, K. R., Berens, T., Coons, S. W., Watts, G. S., Trent, J. M., Wei, J. S., Giese, A. & Berens, M. E., 2001, In : Journal of Neuro-Oncology. 53, 2, p. 161-176 16 p.

Research output: Contribution to journalArticle

Microarray Analysis
Oligonucleotide Array Sequence Analysis
Glioma
Cell Movement
Complementary DNA
91 Citations (Scopus)

Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen Zearalenone-induced cell-cycle progression in MCF-7 cells

Calaluce, R., Kunkel, M. W., Watts, G. S., Schmelz, M., Hao, J., Barrera, J., Gleason-Guzman, M., Isett, R., Fitchmun, M., Tim Bowden, G., Cress, A. E., Futscher, B. W. & Nagle, R. B., 2001, In : Molecular Carcinogenesis. 30, 2, p. 88-98 11 p.

Research output: Contribution to journalArticle

Zearalenone
MCF-7 Cells
Signal Transduction
Cell Cycle
G2 Phase
1997
180 Citations (Scopus)
CpG Islands
Transcription Initiation Site
Methyltransferases
Gene Silencing
Methylation
1995
2 Citations (Scopus)
5-Methylcytosine
Cultured Tumor Cells
Restriction Mapping
Thymidine Kinase
Cytosine