• 2235 Citations
  • 20 h-Index
20002020

Research output per year

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Research Output

  • 2235 Citations
  • 20 h-Index
  • 29 Article
  • 2 Short survey
  • 1 Conference contribution
  • 1 Review article
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Article
2020

The role of tumor-stroma interactions on desmoplasia and tumorigenicity within a microengineered 3D platform

Saini, H., Rahmani Eliato, K., Veldhuizen, J., Zare, A., Allam, M., Silva, C., Kratz, A., Truong, D., Mouneimne, G., LaBaer, J., Ros, R. & Nikkhah, M., Jul 2020, In : Biomaterials. 247, 119975.

Research output: Contribution to journalArticle

2019

A human organotypic microfluidic tumor model permits investigation of the interplay between patient-derived fibroblasts and breast cancer cells

Truong, D. D., Kratz, A., Park, J. G., Barrientos, E. S., Saini, H., Nguyen, T., Pockaj, B., Mouneimne, G., LaBaer, J. & Nikkhah, M., Jun 15 2019, In : Cancer Research. 79, 12, p. 3139-3151 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Insulin induces microtubule stabilization and regulates the microtubule plus-end tracking protein network in adipocytes

Parker, S. S., Krantz, J., Kwak, E. A., Barker, N. K., Deer, C. G., Lee, N. Y., Mouneimne, G. & Langlais, P. R., Jan 1 2019, In : Molecular and Cellular Proteomics. 18, 7, p. 1363-1381 19 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mechanosensing during directed cell migration requires dynamic actin polymerization at focal adhesions

Puleo, J. I., Parker, S. S., Roman, M. R., Watson, A. W., Eliato, K. R., Peng, L., Saboda, K., Roe, D. J., Ros, R., Gertler, F. B. & Mouneimne, G., Dec 2 2019, In : The Journal of cell biology. 218, 12, p. 4215-4235 21 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

High Fidelity Cryopreservation and Recovery of Primary Rodent Cortical Neurons

Parker, S. S., Moutal, A., Cai, S., Chandrasekaran, S., Roman, M. R., Koshy, A. A., Khanna, R., Zinsmaier, K. E. & Mouneimne, G., Sep 1 2018, In : eNeuro. 5, 5

Research output: Contribution to journalArticle

1 Scopus citations

Microfluidic Tumor–Vascular Model to Study Breast Cancer Cell Invasion and Intravasation

Nagaraju, S., Truong, D., Mouneimne, G. & Nikkhah, M., May 9 2018, In : Advanced Healthcare Materials. 7, 9, 1701257.

Research output: Contribution to journalArticle

24 Scopus citations

The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion

Padilla-Rodriguez, M., Parker, S. S., Adams, D. G., Westerling, T., Puleo, J. I., Watson, A. W., Hill, S. M., Noon, M., Gaudin, R., Aaron, J., Tong, D., Roe, D. J., Knudsen, B. & Mouneimne, G., Dec 1 2018, In : Nature communications. 9, 1, 2980.

Research output: Contribution to journalArticle

7 Scopus citations

The Role of Desmoplasia and Stromal Fibroblasts on Anti-cancer Drug Resistance in a Microengineered Tumor Model

Saini, H., Rahmani Eliato, K., Silva, C., Allam, M., Mouneimne, G., Ros, R. & Nikkhah, M., Jan 1 2018, (Accepted/In press) In : Cellular and Molecular Bioengineering.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Effect of suberoylanilide hydroxamic acid (SAHA) on breast cancer cells within a tumor-stroma microfluidic model

Peela, N., Barrientos, E. S., Truong, D., Mouneimne, G. & Nikkhah, M., Dec 1 2017, In : Integrative Biology (United Kingdom). 9, 12, p. 988-999 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

A three dimensional micropatterned tumor model for breast cancer cell migration studies

Peela, N., Sam, F. S., Christenson, W., Truong, D., Watson, A. W., Mouneimne, G., Ros, R. & Nikkhah, M., Mar 1 2016, In : Biomaterials. 81, p. 72-83 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

Breast cancer cell invasion into a three dimensional tumor-stroma microenvironment

Truong, D., Puleo, J., Llave, A., Mouneimne, G., Kamm, R. D. & Nikkhah, M., Sep 28 2016, In : Scientific Reports. 6, 34094.

Research output: Contribution to journalArticle

52 Scopus citations

Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE

Carmona, G., Perera, U., Gillett, C., Naba, A., Law, A. L., Sharma, V. P., Wang, J., Wyckoff, J., Balsamo, M., Mosis, F., De Piano, M., Monypenny, J., Woodman, N., McConnell, R. E., Mouneimne, G., Van Hemelrijck, M., Cao, Y., Condeelis, J., Hynes, R. O., Gertler, F. B. & 1 others, Krause, M., Sep 29 2016, In : Oncogene. 35, 39, p. 5155-5169 15 p.

Research output: Contribution to journalArticle

31 Scopus citations
2012

DIAPH3 governs the cellular transition to the amoeboid tumour phenotype

Hager, M. H., Morley, S., Bielenberg, D. R., Gao, S., Morello, M., Holcomb, I. N., Liu, W., Mouneimne, G., Demichelis, F., Kim, J., Solomon, K. R., Adam, R. M., Isaacs, W. B., Higgs, H. N., Vessella, R. L., Di Vizio, D. & Freeman, M. R., Aug 1 2012, In : EMBO Molecular Medicine. 4, 8, p. 743-760 18 p.

Research output: Contribution to journalArticle

50 Scopus citations

Differential Remodeling of Actin Cytoskeleton Architecture by Profilin Isoforms Leads to Distinct Effects on Cell Migration and Invasion

Mouneimne, G., Hansen, S. D., Selfors, L. M., Petrak, L., Hickey, M. M., Gallegos, L. L., Simpson, K. J., Lim, J., Gertler, F. B., Hartwig, J. H., Mullins, R. D. & Brugge, J. S., Nov 13 2012, In : Cancer Cell. 22, 5, p. 615-630 16 p.

Research output: Contribution to journalArticle

86 Scopus citations
2011

Psidin, a conserved protein that regulates protrusion dynamics and cell migration

Kim, J. H., Cho, A., Yin, H., Schafer, D. A., Mouneimne, G., Simpson, K. J., Nguyen, K. V., Brugge, J. S. & Montell, D. J., Apr 1 2011, In : Genes and Development. 25, 7, p. 730-741 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
2009

N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells

DesMarais, V., Yamaguchi, H., Oser, M., Soon, L., Mouneimne, G., Sarmiento, C., Eddy, R. & Condeelis, J., Jun 1 2009, In : Cell Motility and the Cytoskeleton. 66, 6, p. 303-316 14 p.

Research output: Contribution to journalArticle

79 Scopus citations
2007

A Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion

Overholtzer, M., Mailleux, A. A., Mouneimne, G., Normand, G., Schnitt, S. J., King, R. W., Cibas, E. S. & Brugge, J. S., Nov 30 2007, In : Cell. 131, 5, p. 966-979 14 p.

Research output: Contribution to journalArticle

355 Scopus citations

Cofilin determines the migration behavior and turning frequency of metastatic cancer cells

Sidani, M., Wessels, D., Mouneimne, G., Ghosh, M., Goswami, S., Sarmiento, C., Wang, W., Kuhl, S., El-Sibai, M., Backer, J. M., Eddy, R., Soll, D. & Condeelis, J., Nov 19 2007, In : Journal of Cell Biology. 179, 4, p. 777-791 15 p.

Research output: Contribution to journalArticle

133 Scopus citations

The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration

Yip, S. C., El-Sibai, M., Coniglio, S. J., Mouneimne, G., Eddy, R. J., Drees, B. E., Neilsen, P. O., Goswami, S., Symons, M., Condeelis, J. S. & Backer, J. M., Sep 1 2007, In : Journal of Cell Science. 120, 17, p. 3138-3146 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

ZBP1 enhances cell polarity and reduces chemotaxis

Lapidus, K., Wyckoff, J., Mouneimne, G., Lorenz, M., Soon, L., Condeelis, J. S. & Singer, R. H., Sep 15 2007, In : Journal of Cell Science. 120, 18, p. 3173-3178 6 p.

Research output: Contribution to journalArticle

32 Scopus citations
2006

Initiation of cofilin activity in response to EGF is uncoupled from cofilin phosphorylation and dephosphorylation in carcinoma cells

Song, X., Chen, X., Yamaguchi, H., Mouneimne, G., Condeelis, J. S. & Eddy, R. J., Jul 15 2006, In : Journal of Cell Science. 119, 14, p. 2871-2881 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Spatial and Temporal Control of Cofilin Activity Is Required for Directional Sensing during Chemotaxis

Mouneimne, G., DesMarais, V., Sidani, M., Scemes, E., Wang, W., Song, X., Eddy, R. & Condeelis, J., Nov 21 2006, In : Current Biology. 16, 22, p. 2193-2205 13 p.

Research output: Contribution to journalArticle

133 Scopus citations

The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors

Wang, W., Mouneimne, G., Sidani, M., Wyckoff, J., Chen, X., Makris, A., Goswami, S., Bresnick, A. R. & Condeelis, J. S., May 8 2006, In : Journal of Cell Biology. 173, 3, p. 395-404 10 p.

Research output: Contribution to journalArticle

197 Scopus citations
2005

Description and characterization of a chamber for viewing and quantifying cancer cell chemotaxis

Soon, L., Mouneimne, G., Segall, J., Wyckoff, J. & Condeelis, J., Sep 1 2005, In : Cell Motility and the Cytoskeleton. 62, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2004

Cellular localization of activated N-WASP using a conformation-sensitive antibody

Sukumvanich, P., DesMarais, V., Sarmiento, C. V., Wang, Y., Ichetovkin, I., Mouneimne, G., Almo, S. & Condeelis, J., Oct 1 2004, In : Cell Motility and the Cytoskeleton. 59, 2, p. 141-152 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Cofilin Promotes Actin Polymerization and Defines the Direction of Cell Motility

Ghosh, M., Song, X., Mouneimne, G., Sidani, M., Lawrence, D. S. & Condeelis, J. S., Apr 30 2004, In : Science. 304, 5671, p. 743-746 4 p.

Research output: Contribution to journalArticle

508 Scopus citations
21 Scopus citations

Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation

Mouneimne, G., Soon, L., DesMarais, V., Sidani, M., Song, X., Yip, S. C., Ghosh, M., Eddy, R., Backer, J. M. & Condeelis, J., Aug 30 2004, In : Journal of Cell Biology. 166, 5, p. 697-708 12 p.

Research output: Contribution to journalArticle

192 Scopus citations
2000

Functional interplay between gelatinases and hyperalgesia in endotoxin-induced localized inflammatory pain

Talhouk, R. S., Hajjar, L., Abou-Gergi, R., Simaa'n, C. J., Mouneimne, G., Saade', N. E. & Safieh-Garabedian, B., Feb 1 2000, In : Pain. 84, 2-3, p. 397-405 9 p.

Research output: Contribution to journalArticle

20 Scopus citations