• 2333 Citations
  • 12 h-Index
19992018
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Research Output 1999 2018

  • 2333 Citations
  • 12 h-Index
  • 23 Article
  • 1 Chapter
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Article
2017
1 Citations

Controlling Depth of Cellular Quiescence by an Rb-E2F Network Switch

Kwon, J. S., Everetts, N. J., Wang, X., Wang, W., Della Croce, K., Xing, J. & Yao, G. Sep 26 2017 In : Cell Reports. 20, 13, p. 3223-3235 13 p.

Research output: Contribution to journalArticle

Retinoblastoma
Switches
Chemical activation
Network components
Repair
5 Citations

Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum

Dai, J., Miller, M. A., Everetts, N. J., Wang, X., Li, P., Li, Y., Xu, J. H. & Yao, G. 2017 In : Oncotarget. 8, 8, p. 13770-13781 12 p.

Research output: Contribution to journalArticle

Reishi
Neoplasms
Neoplastic Stem Cells
Agaricales
Chinese Traditional Medicine
1 Citations

Exit from quiescence displays a memory of cell growth and division

Wang, X., Fujimaki, K., Mitchell, G. C., Kwon, J. S., Della Croce, K., Langsdorf, C., Zhang, H. H. & Yao, G. Dec 1 2017 In : Nature Communications. 8, 1, 321

Research output: Contribution to journalArticle

Cell growth
Cell Division
division
Data storage equipment
Growth
3 Citations

Expression level is a key determinant of E2F1-mediated cell fate

Shats, I., Deng, M., Davidovich, A., Zhang, C., Kwon, J. S., Manandhar, D., Gordân, R., Yao, G. & You, L. Apr 1 2017 In : Cell Death and Differentiation. 24, 4, p. 626-637 12 p.

Research output: Contribution to journalArticle

Apoptosis
Neoplasms
G2 Phase Cell Cycle Checkpoints
Single-Cell Analysis
RNA Sequence Analysis
2016
3 Citations

Antitumor effects and mechanisms of Ganoderma extracts and spores oil

Chen, C., Li, P., Li, Y., Yao, G. & Xu, J. H. Nov 1 2016 In : Oncology Letters. 12, 5, p. 3571-3578 8 p.

Research output: Contribution to journalArticle

Ganoderma
Spores
Oils
Type II DNA Topoisomerase
Type I DNA Topoisomerase
2015
4 Citations

Ovarian serous carcinogenesis from tubal secretory cells

Zhang, W., Wei, L., Li, L., Yang, B., Kong, B., Yao, G. & Zheng, W. Nov 1 2015 In : Histology and Histopathology. 30, 11, p. 1295-1302 8 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Carcinogenesis
Fallopian Tubes
Pathologic Processes
Cause of Death
2014
3 Citations

IMP3 signatures of fallopian tube: A risk for pelvic serous cancers

Wang, Y., Wang, Y., Li, D., Li, L., Zhang, W., Yao, G., Jiang, Z. & Zheng, W. Jul 12 2014 In : Journal of Hematology and Oncology. 7, 1, 49

Research output: Contribution to journalArticle

Pelvic Neoplasms
Fallopian Tubes
Carcinoma
Carcinogenesis
Mucous Membrane
4 Citations

Linear population allocation by bistable switches in response to transient stimulation

Srimani, J. K., Yao, G., Neu, J., Tanouchi, Y., Lee, T. J. & You, L. Aug 20 2014 In : PLoS One. 9, 8, e105408

Research output: Contribution to journalArticle

Switches
Population
duration
Computer simulation
cells
27 Citations

Modelling mammalian cellular quiescence

Yao, G. 2014 In : Interface Focus. 4, 3

Research output: Contribution to journalArticle

Switches
Mammals
Lymphocytes
Cell proliferation
Fibroblasts
1 Citations

Systematic reverse engineering of network topologies: A case study of resettable bistable cellular responses

Mondal, D., Dougherty, E., Mukhopadhyay, A., Carbo, A., Yao, G. & Xing, J. Aug 29 2014 In : PLoS One. 9, 8, e105833

Research output: Contribution to journalArticle

Reverse engineering
topology
engineering
Topology
case studies
2011
63 Citations

Origin of bistability underlying mammalian cell cycle entry

Yao, G., Tan, C., West, M., Nevins, J. R. & You, L. 2011 In : Molecular Systems Biology. 7, 485

Research output: Contribution to journalArticle

Bistability
Gene Regulatory Networks
Cell Cycle
Cell Cycle Checkpoints
cell cycle
2 Citations

Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells

Wong, J. V., Yao, G., Nevins, J. R. & You, L. 2011 In : Methods in Enzymology. 497, p. 221-237 17 p.

Research output: Contribution to journalArticle

Cytology
Cell Physiological Phenomena
Physiology
Adenoviridae
Gene expression
34 Citations

Viral-Mediated Noisy Gene Expression Reveals Biphasic E2f1 Response to MYC

Wong, J. V., Yao, G., Nevins, J. R. & You, L. Feb 4 2011 In : Molecular Cell. 41, 3, p. 275-285 11 p.

Research output: Contribution to journalArticle

Gene Expression
Gene Expression Regulation
Serum
MicroRNAs
Noise
2010
29 Citations

Stochastic E2F activation and Reconciliation of phenomenological Cell-Cycle Models

Lee, T. J., Yao, G., Bennett, D. C., Nevins, J. R. & You, L. Sep 2010 In : PLoS Biology. 8, 9, e1000488

Research output: Contribution to journalArticle

cell cycle
Cell Cycle
Chemical activation
Cells
Growth
2009
124 Citations

Anchorage-independent cell growth signature identifies tumors with metastatic potential

Mori, S., Chang, J. T., Andrechek, E. R., Matsumura, N., Baba, T., Yao, G., Kim, J. W., Gatza, M., Murphy, S. & Nevins, J. R. Aug 6 2009 In : Oncogene. 28, 31, p. 2796-2805 10 p.

Research output: Contribution to journalArticle

Growth
Phenotype
Neoplasms
Oligonucleotide Array Sequence Analysis
Cell Biology
2008
201 Citations

A bistable Rb-E2F switch underlies the restriction point

Yao, G., Lee, T. J., Mori, S., Nevins, J. R. & You, L. 2008 In : Nature Cell Biology. 10, 4, p. 476-482 7 p.

Research output: Contribution to journalArticle

Serum
Cell Cycle
Homeostasis
Growth
Neoplasms
33 Citations

Sensing and integration of Erk and PI3K signals by Myc

Lee, T., Yao, G., Nevins, J. & You, L. Feb 2008 In : PLoS Computational Biology. 4, 2

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Extracellular Signal-Regulated MAP Kinases
phosphatidylinositol 3-kinase
mitogen-activated protein kinase
Sensing
39 Citations

Utilization of pathway signatures to reveal distinct types of B lymphoma in the Eμ-myc model and human diffuse large B-cell lymphoma

Mori, S., Rempel, R. E., Chang, J. T., Yao, G., Lagoo, A. S., Potti, A., Bild, A. & Nevins, J. R. Oct 15 2008 In : Cancer Research. 68, 20, p. 8525-8534 10 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Lymphoma
Gene Expression
Burkitt Lymphoma
B-Cell Lymphoma
2006
1353 Citations

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

Bild, A. H., Yao, G., Chang, J. T., Wang, Q., Potti, A., Chasse, D., Joshi, M. B., Harpole, D., Lancaster, J. M., Berchuck, A., Olson, J. A., Marks, J. R., Dressman, H. K., West, M. & Nevins, J. R. Jan 19 2006 In : Nature. 439, 7074, p. 353-357 5 p.

Research output: Contribution to journalArticle

Transcriptome
Neoplasms
Therapeutics
Neoplasm Genes
Therapeutic Uses
2005

DIG - A system for gene annotation and functional discovery

DeLong, M., Yao, G., Wang, Q., Dobra, A., Black, E. P., Chang, J. T., Bild, A., West, M., Nevins, J. R. & Dressman, H. Jul 1 2005 In : Bioinformatics. 21, 13, p. 2957-2959 3 p.

Research output: Contribution to journalArticle

Molecular Sequence Annotation
Genomics
Annotation
Genes
Gene
2004
19 Citations

Interaction networks in yeast define and enumerate the signaling steps of the vertebrate aryl hydrocarbon receptor

Yao, G., Craven, M., Drinkwater, N. & Bradfield, C. A. 2004 In : PLoS Biology. 2, 3

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Yeast
Vertebrates
hydrocarbons
Yeasts
231 Citations

Sparse graphical models for exploring gene expression data

Dobra, A., Hans, C., Jones, B., Nevins, J. R., Yao, G. & West, M. Jul 2004 In : Journal of Multivariate Analysis. 90, 1 SPEC. ISS., p. 196-212 17 p.

Research output: Contribution to journalArticle

Graphical Models
Gene Expression Data
Gene expression
Pathway
Estrogen Receptor
1999
153 Citations

Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways: Demonstration of competition and compensation

Chan, W. K., Yao, G., Gu, Y. Z. & Bradfield, C. A. Apr 23 1999 In : Journal of Biological Chemistry. 274, 17, p. 12115-12123 9 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Dioxins
Erythropoietin
Demonstrations
Transcription