Hendrikus "Henk" Granzier

  • 13257 Citations
  • 63 h-Index
1983 …2018
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  • 5 Similar Profiles
Connectin Medicine & Life Sciences
Sarcomeres Medicine & Life Sciences
Muscles Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences
Myocardium Medicine & Life Sciences
Muscle Chemical Compounds
Nemaline Myopathies Medicine & Life Sciences

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Projects 1995 2018

Myofilament-based mechanisms of diastolic dysfunction in HFpEF

Granzier, H. ". & Lewinter, M.

National Institutes of Health

9/1/146/30/18

Project: Research projectResearch Project

Myofibrils
Connectin
Heart Failure
Troponin I
Phosphorylation

Titin-based adaptations of cardiac function

Granzier, H. ".

National Institutes of Health

3/1/131/31/17

Project: Research projectResearch Project

Connectin
Protein Isoforms
Starlings
Hypertrophy
Extracellular Matrix
Connectin
Skeletal Muscle
Muscles
Proteins
Hypertrophy
Connectin
Muscle Development
Skeletal Muscle
Muscular Atrophy
Myocardium
Muscles
Nemaline Myopathies
Skeletal Muscle
nebulin
Sarcomeres

Research Output 1983 2018

  • 13257 Citations
  • 63 h-Index
  • 212 Article
  • 2 Review article
  • 1 Comment/debate
  • 1 Letter

Correction to: The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease (Biophysical Reviews, (2017), 9, 4, (431-441), 10.1007/s12551-017-0305-3)

dos Remedios, C. G., Lal, S. P., Li, A., McNamara, J., Keogh, A., Macdonald, P. S., Cooke, R., Ehler, E., Knöll, R., Marston, S. B., Stelzer, J., Granzier, H., Bezzina, C., van Dijk, S., De Man, F., Stienen, G. J. M., Odeberg, J., Pontén, F., Linke, W. A. & van der Velden, J. Jun 1 2018 In : Biophysical Reviews. 10, 3, 1 p.

Research output: Contribution to journalComment/debate

Translational Medical Research
Names
Heart Diseases
Animal Models

Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism

Jeong, M. Y., Lin, Y. H., Wennersten, S. A., Demos-Davies, K. M., Cavasin, M. A., Mahaffey, J. H., Monzani, V., Saripalli, C., Mascagni, P., Reece, T. B., Ambardekar, A. V., Granzier, H. L., Dinarello, C. A. & McKinsey, T. A. Feb 7 2018 In : Science Translational Medicine. 10, 427, eaao0144

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Histone Deacetylases
Myofibrils
Left Ventricular Dysfunction
Treatment Failure
8 Citations

219th ENMC International Workshop Titinopathies International database of titin mutations and phenotypes, Heemskerk, The Netherlands, 29 April–1 May 2016

Hackman, P. , Udd, B. , Bönnemann, C. G. , Ferreiro, A. , Udd, B. , Hackman, P. , Ferreiro, A. , Bonnemann, C. , Beggs, A. , Gautel, M. , Davis, M. , Evangelista, T. , Savarese, M. , Glumac, J. N. , Laporte, J. , Smith, J. E. , Richard, I. , Granzier, H. , Schneider, R. , Jungbluth, H. & 3 others Foye, S., Frase, A. R. & Titinopathy Database Consortium Apr 1 2017 In : Neuromuscular Disorders. 27, 4, p. 396-407 12 p.

Research output: Contribution to journalArticle

1 Citations

Effect of exercise on passive myocardial stiffness in mice with diastolic dysfunction

Slater, R. E., Strom, J. G. & Granzier, H. Jul 1 2017 In : Journal of Molecular and Cellular Cardiology. 108, p. 24-33 10 p.

Research output: Contribution to journalArticle

Connectin
Exercise
ivabradine
Heart Rate
Phosphorylation
1 Citations

Muscle weakness in respiratory and peripheral skeletal muscles in a mouse model for nebulin-based nemaline myopathy

Joureau, B., de Winter, J. M., Stam, K., Granzier, H. & Ottenheijm, C. A. C. Jan 1 2017 In : Neuromuscular Disorders. 27, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

Nemaline Myopathies
Muscle Weakness
Diaphragm
Skeletal Muscle
Muscles