Hendrikus "Henk" Granzier

  • 13557 Citations
  • 64 h-Index
1983 …2018
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  • 5 Similar Profiles
Connectin Medicine & Life Sciences
Sarcomeres Medicine & Life Sciences
Muscles Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences
Myocardium Medicine & Life Sciences
Muscle Chemical Compounds
Nemaline Myopathies Medicine & Life Sciences

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Projects 1995 2018

Myofilament-based mechanisms of diastolic dysfunction in HFpEF

Granzier, H. ". & Lewinter, M.

National Institutes of Health

9/1/146/30/18

Project: Research projectResearch Project

Myofibrils
Connectin
Heart Failure
Troponin I
Phosphorylation

Titin-based adaptations of cardiac function

Granzier, H. ".

National Institutes of Health

3/1/131/31/17

Project: Research projectResearch Project

Connectin
Protein Isoforms
Starlings
Hypertrophy
Extracellular Matrix
Connectin
Skeletal Muscle
Muscles
Proteins
Hypertrophy
Connectin
Muscle Development
Skeletal Muscle
Muscular Atrophy
Myocardium

Research Output 1983 2018

  • 13557 Citations
  • 64 h-Index
  • 215 Article
  • 2 Review article
  • 1 Comment/debate
  • 1 Letter

Correction to: The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease (Biophysical Reviews, (2017), 9, 4, (431-441), 10.1007/s12551-017-0305-3)

dos Remedios, C. G., Lal, S. P., Li, A., McNamara, J., Keogh, A., Macdonald, P. S., Cooke, R., Ehler, E., Knöll, R., Marston, S. B., Stelzer, J., Granzier, H., Bezzina, C., van Dijk, S., De Man, F., Stienen, G. J. M., Odeberg, J., Pontén, F., Linke, W. A. & van der Velden, J., Jun 1 2018, In : Biophysical Reviews. 10, 3, 1 p.

Research output: Contribution to journalComment/debate

Translational Medical Research
Names
Heart Diseases
Animal Models
5 Citations

Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism

Jeong, M. Y., Lin, Y. H., Wennersten, S. A., Demos-Davies, K. M., Cavasin, M. A., Mahaffey, J. H., Monzani, V., Saripalli, C., Mascagni, P., Reece, T. B., Ambardekar, A. V., Granzier, H. L., Dinarello, C. A. & McKinsey, T. A., Feb 7 2018, In : Science Translational Medicine. 10, 427, eaao0144

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Histone Deacetylases
Myofibrils
Left Ventricular Dysfunction
Treatment Failure
1 Citations

Positive end-expiratory pressure ventilation induces longitudinal atrophy in diaphragm fibers

Lindqvist, J., Van Den Berg, M., Van Der Pijl, R., Hooijman, P. E., Beishuizen, A., Elshof, J., De Waard, M., Girbes, A., Spoelstra-De Man, A., Shi, Z. H., Van Den Brom, C., Bogaards, S., Shen, S., Strom, J., Granzier, H., Kole, J., Musters, R. J. P., Paul, M. A., Heunks, L. M. A. & Ottenheijm, C. A. C., Aug 15 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 4, p. 472-485 14 p.

Research output: Contribution to journalArticle

Positive-Pressure Respiration
Diaphragm
Atrophy
Connectin
Critical Illness

Thick-Filament Extensibility in Intact Skeletal Muscle

Ma, W., Gong, H., Kiss, B., Lee, E. J., Granzier, H. & Irving, T., Jan 1 2018, (Accepted/In press) In : Biophysical Journal.

Research output: Contribution to journalArticle

Myosins
Skeletal Muscle
Periodicity
Connectin
Calcium
1 Citations

Titin-based mechanosensing modulates muscle hypertrophy

van der Pijl, R., Strom, J., Conijn, S., Lindqvist, J., Labeit, S., Granzier, H. & Ottenheijm, C., Jan 1 2018, (Accepted/In press) In : Journal of Cachexia, Sarcopenia and Muscle.

Research output: Contribution to journalArticle

Connectin
Hypertrophy
Muscles
Denervation
Diaphragm