Research Output per year
Research Output 1995 2017
- 1 - 50 out of 62 results
- Type (ascending)
A coiled-coil enabled split-luciferase three-hybrid system: Applied toward profiling inhibitors of protein kinases
Jester, B. W., Cox, K. J., Gaj, A., Shomin, C. D., Porter, J. R. & Ghosh, I., Aug 25 2010, In : Journal of the American Chemical Society. 132, 33, p. 11727-11735 9 p.Research output: Contribution to journal › Article
A comprehensive panel of turn-on caspase biosensors for investigating caspase specificity and caspase activation pathways
Shekhawat, S. S., Campbell, S. T. & Ghosh, I., Oct 17 2011, In : ChemBioChem. 12, 15, p. 2353-2364 12 p.Research output: Contribution to journal › Article
A fragment-based selection approach for the discovery of peptide macrocycles targeting protein kinases
Restituyo, E., Camacho-Soto, K. & Ghosh, I., 2015, In : Methods in molecular biology (Clifton, N.J.). 1248, p. 95-104 10 p.Research output: Contribution to journal › Article
A general and rapid cell-free approach for the interrogation of protein-protein, protein-DNA, and protein-RNA interactions and their antagonists utilizing split-protein reporters
Porter, J. R., Stains, C. I., Jester, B. W. & Ghosh, I., May 21 2008, In : Journal of the American Chemical Society. 130, 20, p. 6488-6497 10 p.Research output: Contribution to journal › Article
A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly
Stains, C. I., Furman, J. L., Porter, J. R., Rajagopal, S., Li, Y., Wyatt, R. T. & Ghosh, I., Oct 15 2010, In : ACS Chemical Biology. 5, 10, p. 943-952 10 p.Research output: Contribution to journal › Article
A minimalist approach toward protein recognition by epitope transfer from functionally evolved β-sheet surfaces
Rajagopal, S., Meyer, S. C., Goldman, A., Zhou, M. & Ghosh, I., Nov 8 2006, In : Journal of the American Chemical Society. 128, 44, p. 14356-14363 8 p.Research output: Contribution to journal › Article
An autoinhibited coiled-coil design strategy for split-protein protease sensors
Shekhawat, S. S., Porter, J. R., Sriprasad, A. & Ghosh, I., Oct 28 2009, In : Journal of the American Chemical Society. 131, 42, p. 15284-15290 7 p.Research output: Contribution to journal › Article
Antiparallel leucine zipper-directed protein reassembly: Application to the green fluorescent protein [12]
Ghosh, I., Hamilton, A. D. & Regan, L., Jun 14 2000, In : Journal of the American Chemical Society. 122, 23, p. 5658-5659 2 p.Research output: Contribution to journal › Article
A pH-modulated, self-replicating peptide
Yao, S., Ghosh, I., Zutshi, R. & Chmielewski, J., 1997, In : Journal of the American Chemical Society. 119, 43, p. 10559-10560 2 p.Research output: Contribution to journal › Article
A self-replicating peptide under ionic control
Yao, S., Ghosh, I., Zutshi, R. & Chmielewski, J., Mar 2 1998, In : Angewandte Chemie - International Edition. 37, 4, p. 478-481 4 p.Research output: Contribution to journal › Article
A turn-on split-luciferase sensor for the direct detection of poly(ADP-ribose) as a marker for DNA repair and cell death
Furman, J. L., Mok, P. W., Shen, S., Stains, C. I. & Ghosh, I., Jan 7 2011, In : Chemical Communications. 47, 1, p. 397-399 3 p.Research output: Contribution to journal › Article
A β-sheet peptide inhibitor of E47 dimerization and DNA binding
Ghosh, I. & Chmielewski, J., Aug 1998, In : Chemistry and Biology. 5, 8, p. 439-445 7 p.Research output: Contribution to journal › Article
Basic-helix-loop-helix region of tal: Evaluation of structure and DNA affinity
Bishop, P., Ghosh, I., Jones, C. & Chmielewski, J., Aug 9 1995, In : Journal of the American Chemical Society. 117, 31, p. 8283-8284 2 p.Research output: Contribution to journal › Article
Basic–Helix–Loop–Helix Region of Tal: Evaluation of Structure and DNA Affinity
Bishop, P., Ghosh, I., Jones, C. & Chmielewski, J., 1995, In : Journal of the American Chemical Society. 117, 46, p. 11616 1 p.Research output: Contribution to journal › Article
Current trends in peptide science quantum dots and peptides: A bright future together
Zhou, M. & Ghosh, I., 2007, In : Biopolymers - Peptide Science Section. 88, 3, p. 325-339 15 p.Research output: Contribution to journal › Article
Detecting protein-protein interactions with a green fluorescent protein fragment reassembly trap: Scope and mechanism
Magliery, T. J., Wilson, C. G. M., Pan, W., Mishler, D., Ghosh, I., Hamilton, A. D. & Regan, L., Jan 12 2005, In : Journal of the American Chemical Society. 127, 1, p. 146-157 12 p.Research output: Contribution to journal › Article
Direct detection of double-stranded DNA: Molecular methods and applications for DNA diagnostics
Ghosh, I., Stains, C. I., Ooi, A. T. & Segal, D. J., 2006, In : Molecular BioSystems. 2, 11, p. 551-560 10 p.Research output: Contribution to journal › Article
Direct DNA methylation profiling using methyl binding domain proteins
Yu, Y., Blair, S., Gillespie, D., Jensen, R., Myszka, D., Badran, A. H., Ghosh, I. & Chagovetz, A., Jun 15 2010, In : Analytical Chemistry. 82, 12, p. 5012-5019 8 p.Research output: Contribution to journal › Article
DNA binding properties of basic helix-loop-helix fusion proteins of Tal and E47
Ghosh, I., Bishop, P. & Chmielewski, J., 2001, In : Journal of Peptide Research. 57, 5, p. 354-360 7 p.Research output: Contribution to journal › Article
DNA sequence-enabled reassembly of the green fluorescent protein
Stains, C. I., Porter, J. R., Ooi, A. T., Segal, D. J. & Ghosh, I., Aug 10 2005, In : Journal of the American Chemical Society. 127, 31, p. 10782-10783 2 p.Research output: Contribution to journal › Article
Dual surface selection methodology for the identification of thrombin binding epitopes from hotspot biased phage-display libraries
Rajagopal, S., Meza-Romero, R. & Ghosh, I., Mar 22 2004, In : Bioorganic and Medicinal Chemistry Letters. 14, 6, p. 1389-1393 5 p.Research output: Contribution to journal › Article
Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor
Badran, A. H., Furman, J. L., Ma, A. S., Comi, T. J., Porter, J. R. & Ghosh, I., Sep 15 2011, In : Analytical Chemistry. 83, 18, p. 7151-7157 7 p.Research output: Contribution to journal › Article
Helical Supramolecules and Fibers Utilizing Leucine Zipper-Displaying Dendrimers
Zhou, M., Bentley, D. & Ghosh, I., Jan 28 2004, In : Journal of the American Chemical Society. 126, 3, p. 734-735 2 p.Research output: Contribution to journal › Article
Highly selective cyclic peptide ligands for neutravidin and avidin identified by phage display
Meyer, S. C., Gaj, T. & Ghosh, I., Jul 2006, In : Chemical Biology and Drug Design. 68, 1, p. 3-10 8 p.Research output: Contribution to journal › Article
High specificity in protein recognition by hydrogen-bond-surrogate α-helices: Selective inhibition of the p53/MDM2 complex
Henchey, L. K., Porter, J. R., Ghosh, I. & Arora, P. S., Oct 18 2010, In : ChemBioChem. 11, 15, p. 2104-2107 4 p.Research output: Contribution to journal › Article
Inhibition of spontaneous receptor phosphorylation by residues in a putative α-helix in the KIT intracellular juxtamembrane region
Ma, Y., Cunningham, M. E., Wang, X., Ghosh, I., Regan, L. & Longley, B. J., May 7 1999, In : Journal of Biological Chemistry. 274, 19, p. 13399-13402 4 p.Research output: Contribution to journal › Article
Inhibition of β-amyloid fibrillization by directed evolution of a β-sheet presenting miniature protein
Smith, T. J., Stains, C. I., Meyer, S. C. & Ghosh, I., Nov 15 2006, In : Journal of the American Chemical Society. 128, 45, p. 14456-14457 2 p.Research output: Contribution to journal › Article
Ligand-gated split-kinases
Camacho-Soto, K., Castillo-Montoya, J., Tye, B. & Ghosh, I., Mar 12 2014, In : Journal of the American Chemical Society. 136, 10, p. 3995-4002 8 p.Research output: Contribution to journal › Article
Mapping the BH3 binding interface of Bcl-x<inf>L</inf>, Bcl-2, and Mcl-1 using split-luciferase reassembly
Campbell, S. T., Carlson, K. J., Buchholz, C. J., Helmers, M. R. & Ghosh, I., Apr 28 2015, In : Biochemistry. 54, 16, p. 2632-2643 12 p.Research output: Contribution to journal › Article
Molecules that target beta-amyloid
Stains, C. I., Mondal, K. & Ghosh, I., Dec 10 2007, In : ChemMedChem. 2, 12, p. 1674-1692 19 p.Research output: Contribution to journal › Article
New directions in targeting protein kinases: Focusing upon true allosteric and bivalent inhibitors
Lamba, V. & Ghosh, I., Jul 2012, In : Current Pharmaceutical Design. 18, 20, p. 2936-2945 10 p.Research output: Contribution to journal › Article
Noncovalent multivalent assembly of jun peptides on a leucine zipper dendrimer displaying fos peptides
Zhou, M. & Ghosh, I., Sep 30 2004, In : Organic Letters. 6, 20, p. 3561-3564 4 p.Research output: Contribution to journal › Article
Parsing the motion of single molecules: a novel algorithm for deconvoluting the dynamics of individual receptors at the cell surface.
Ghosh, I. & Wirth, M. J., Jun 16 2007, In : Science's STKE : signal transduction knowledge environment. 2007, 388Research output: Contribution to journal › Article
Peptide-labeled quantum dots for imaging GPCRs in whole cells and as single molecules
Zhou, M., Nakatani, E., Gronenberg, L. S., Tokimoto, T., Wirth, M. J., Hruby, V. J., Roberts, A., Lynch, R. & Ghosh, I., Mar 2007, In : Bioconjugate Chemistry. 18, 2, p. 323-332 10 p.Research output: Contribution to journal › Article
Peptide self-assembly as a model of proteins in the pre-genomic world
Ghosh, I. & Chmielewski, J., Dec 2004, In : Current Opinion in Chemical Biology. 8, 6, p. 640-644 5 p.Research output: Contribution to journal › Article
Probing orientations of single fluorescent labels on a peptide reversibly binding to the human delta-opioid receptor
Tokimoto, T., Bethea, T. R. C., Zhou, M., Ghosh, I. & Wirth, M. J., Feb 2007, In : Applied Spectroscopy. 61, 2, p. 130-137 8 p.Research output: Contribution to journal › Article
Profiling small molecule inhibitors against helix-receptor interactions: The Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2
Porter, J. R., Helmers, M. R., Wang, P., Furman, J. L., Joy, S. T., Arora, P. S. & Ghosh, I., Nov 14 2010, In : Chemical Communications. 46, 42, p. 8020-8022 3 p.Research output: Contribution to journal › Article
Selection of cyclic-peptide inhibitors targeting Aurora kinase A: Problems and solutions
Shomin, C. D., Restituyo, E., Cox, K. J. & Ghosh, I., Nov 15 2011, In : Bioorganic and Medicinal Chemistry. 19, 22, p. 6743-6749 7 p.Research output: Contribution to journal › Article
Selective amplification by auto- and cross-catalysis in a replicating peptide system
Yao, S., Ghosh, I., Zutshi, R. & Chmielewski, J., Dec 3 1998, In : Nature. 396, 6710, p. 447-450 4 p.Research output: Contribution to journal › Article
Sequence-enabled reassembly of β-lactamase (SEER-LAC): A sensitive method for the detection of double-stranded DNA
Ooi, A. T., Stains, C. I., Ghosh, I. & Segal, D. J., Mar 21 2006, In : Biochemistry. 45, 11, p. 3620-3625 6 p.Research output: Contribution to journal › Article
Single-site mutations in a hyperthermophilic variant of the B1 domain of protein G result in self-assembled oligomers
Meyer, S. C., Huerta, C. & Ghosh, I., Feb 22 2005, In : Biochemistry. 44, 7, p. 2360-2368 9 p.Research output: Contribution to journal › Article
Site-specific detection of DNA methylation utilizing mCpG-SEER
Stains, C. I., Furman, J. L., Segal, D. J. & Ghosh, I., Aug 2 2006, In : Journal of the American Chemical Society. 128, 30, p. 9761-9765 5 p.Research output: Contribution to journal › Article
Small molecule gated split-tyrosine phosphatases and orthogonal split-tyrosine kinases
Camacho-Soto, K., Castillo-Montoya, J., Tye, B., Ogunleye, L. O. & Ghosh, I., Dec 10 2014, In : Journal of the American Chemical Society. 136, 49, p. 17078-17086 9 p.Research output: Contribution to journal › Article
Split-protein systems: Beyond binary protein-protein interactions
Shekhawat, S. S. & Ghosh, I., Dec 2011, In : Current Opinion in Chemical Biology. 15, 6, p. 790-797 8 p.Research output: Contribution to journal › Article
Split β-lactamase sensor for the sequence-specific detection of DNA methylation
Porter, J. R., Stains, C. I., Segal, D. J. & Ghosh, I., Sep 1 2007, In : Analytical Chemistry. 79, 17, p. 6702-6708 7 p.Research output: Contribution to journal › Article
Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): Optimization and selectivity profiling
Shomin, C. D., Meyer, S. C. & Ghosh, I., Sep 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 17, p. 6196-6202 7 p.Research output: Contribution to journal › Article
Structure-function relationship in a β-sheet peptide Inhibitor of E47 dimerization and DNA binding
Ghosh, I., Issac, R. & Chmielewski, J., Jan 1999, In : Bioorganic and Medicinal Chemistry. 7, 1, p. 61-66 6 p.Research output: Contribution to journal › Article
Synthesis of the basic-helix-loop-helix region of the immunoglobulin enhancer binding protein E47 and evaluation of its structural and DNA binding properties
Bishop, P., Jones, C., Ghosh, I. & Chmielewski, J., 1995, In : International Journal of Peptide and Protein Research. 46, 2, p. 149-154 6 p.Research output: Contribution to journal › Article
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA
Furman, J. L., Badran, A. H., Shen, S., Stains, C. I., Hannallah, J., Segal, D. J. & Ghosh, I., Jul 15 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 14, p. 3748-3751 4 p.Research output: Contribution to journal › Article
Testing the promiscuity of commercial kinase inhibitors against the AGC kinase group using a split-luciferase screen
Jester, B. W., Gaj, A., Shomin, C. D., Cox, K. J. & Ghosh, I., Feb 23 2012, In : Journal of Medicinal Chemistry. 55, 4, p. 1526-1537 12 p.Research output: Contribution to journal › Article