• 2904 Citations
  • 27 h-Index
1991 …2020

Research output per year

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Research Output

  • 2904 Citations
  • 27 h-Index
  • 52 Article
  • 4 Review article
  • 2 Letter
  • 1 Conference contribution
2020

Functional characterization of the idtF and idtP genes in the Claviceps paspali indole diterpene biosynthetic gene cluster

Kozák, L., Szilágyi, Z., Tóth, L., Pócsi, I. & Molnár, I., Jun 1 2020, In : Folia Microbiologica. 65, 3, p. 605-613 9 p.

Research output: Contribution to journalArticle

Open Access

Monasone naphthoquinone biosynthesis and resistance in monascus fungi

Li, M., Kang, L., Ding, X., Liu, J., Liu, Q., Shao, Y., Molnár, I. & Chen, F., Jan 1 2020, In : mBio. 11, 1, e02676-19.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Oxidative Stress Induction Is a Rational Strategy to Enhance the Productivity of Antrodia cinnamomea Fermentations for the Antioxidant Secondary Metabolite Antrodin C

Hu, P. F., Huang, J., Chen, L., Ding, Z., Liu, L., Molnár, I. & Zhang, B. B., Apr 1 2020, In : Journal of agricultural and food chemistry. 68, 13, p. 3995-4004 10 p.

Research output: Contribution to journalArticle

2019

Draft Genome Assembly of the Entomopathogenic Bacterium Photorhabdus luminescens subsp. sonorensis Caborca

Duong, D. A., Espinosa-Artiles, P., Orozco, R. A., Molnar, I. & Stock, S. P., Sep 5 2019, In : Microbiology Resource Announcements. 8, 36, e00692-19.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Nature and nurture: Confluence of pathway determinism with metabolic and chemical serendipity diversifies: Monascus azaphilone pigments

Chen, W., Feng, Y., Molnár, I. & Chen, F., Apr 2019, In : Natural Product Reports. 36, 4, p. 561-572 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Rational Reprogramming of O-Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds

Wang, X., Wang, C., Duan, L., Zhang, L., Liu, H., Xu, Y. M., Liu, Q., Mao, T., Zhang, W., Chen, M., Lin, M., Gunatilaka, A. A. L., Xu, Y. & Molnár, I., Mar 13 2019, In : Journal of the American Chemical Society. 141, 10, p. 4355-4364 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Tremorgenic and neurotoxic paspaline-derived indole-diterpenes: biosynthetic diversity, threats and applications

Kozák, L., Szilágyi, Z., Tóth, L., Pócsi, I. & Molnár, I., Feb 15 2019, In : Applied Microbiology and Biotechnology. 103, 4, p. 1599-1616 18 p.

Research output: Contribution to journalReview article

6 Scopus citations
2018

Inactivation of the indole-diterpene biosynthetic gene cluster of Claviceps paspali by Agrobacterium-mediated gene replacement

Kozák, L., Szilágyi, Z., Vágó, B., Kakuk, A., Tóth, L., Molnár, I. & Pócsi, I., Apr 1 2018, In : Applied Microbiology and Biotechnology. 102, 7, p. 3255-3266 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Methylglucosylation of aromatic amino and phenolic moieties of drug-like biosynthons by combinatorial biosynthesis

Xie, L., Zhang, L., Wang, C., Wang, X., Xu, Y. M., Yu, H., Wu, P., Li, S., Han, L., Gunatilaka, A. A. L., Wei, X., Lin, M., Molnár, I. & Xu, Y., May 29 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. E4980-E4989

Research output: Contribution to journalArticle

11 Scopus citations
2017

Antifungal and Cytotoxic β-Resorcylic Acid Lactones from a Paecilomyces Species

Xu, L., Wu, P., Xue, J., Molnar, I. & Wei, X., Aug 25 2017, In : Journal Of Natural Products. 80, 8, p. 2215-2253 39 p.

Research output: Contribution to journalArticle

7 Scopus citations

Orange, red, yellow: Biosynthesis of azaphilone pigments in Monascus fungi

Chen, W., Chen, R., Liu, Q., He, Y., He, K., Ding, X., Kang, L., Guo, X., Xie, N., Zhou, Y., Lu, Y., Cox, R. J., Molnár, I., Li, M., Shao, Y. & Chen, F., 2017, In : Chemical Science. 8, 7, p. 4917-4925 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Review of the algal biology program within the National Alliance for Advanced Biofuels and Bioproducts

Unkefer, C. J., Sayre, R. T., Magnuson, J. K., Anderson, D. B., Baxter, I., Blaby, I. K., Brown, J. K., Carleton, M., Cattolico, R. A., Dale, T., Devarenne, T. P., Downes, C. M., Dutcher, S. K., Fox, D. T., Goodenough, U., Jaworski, J., Holladay, J. E., Kramer, D. M., Koppisch, A. T., Lipton, M. S. & 17 others, Marrone, B. L., McCormick, M., Molnár, I., Mott, J. B., Ogden, K. L., Panisko, E. A., Pellegrini, M., Polle, J., Richardson, J. W., Sabarsky, M., Starkenburg, S. R., Stormo, G. D., Teshima, M., Twary, S. N., Unkefer, P. J., Yuan, J. S. & Olivares, J. A., Mar 1 2017, In : Algal Research. 22, p. 187-215 29 p.

Research output: Contribution to journalArticle

34 Scopus citations
2016

A squalene synthase-like enzyme initiates production of tetraterpenoid hydrocarbons in Botryococcus braunii Race L

Thapa, H. R., Naik, M. T., Okada, S., Takada, K., Molnár, I., Xu, Y. & Devarenne, T. P., Apr 6 2016, In : Nature communications. 7, 11198.

Research output: Contribution to journalArticle

14 Scopus citations

Bioprospecting for secondary metabolites in the entomopathogenic bacterium Photorhabdus luminescens subsp. sonorensis

Orozco, R. A., Molnar, I., Bode, H. & Stock, S. P., Nov 1 2016, In : Journal of Invertebrate Pathology. 141, p. 45-52 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Discrimination and Quantification of True Biological Signals in Metabolomics Analysis Based on Liquid Chromatography-Mass Spectrometry

Duan, L., Molnar, I., Snyder, J. H., Shen, G. A. & Qi, X., Aug 1 2016, In : Molecular Plant. 9, 8, p. 1217-1220 4 p.

Research output: Contribution to journalLetter

6 Scopus citations

Diversity-Oriented Combinatorial Biosynthesis of Hybrid Polyketide Scaffolds from Azaphilone and Benzenediol Lactone Biosynthons

Bai, J., Lu, Y., Xu, Y. M., Zhang, W., Chen, M., Lin, M., Gunatilaka, L., Xu, Y. & Molnar, I., Mar 18 2016, In : Organic Letters. 18, 6, p. 1262-1265 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Insights into Adaptations to a Near-Obligate Nematode Endoparasitic Lifestyle from the Finished Genome of Drechmeria coniospora

Zhang, L., Zhou, Z., Guo, Q., Fokkens, L., Miskei, M., Pócsi, I., Zhang, W., Chen, M., Wang, L., Sun, Y., Donzelli, B. G. G., Gibson, D. M., Nelson, D. R., Luo, J. G., Rep, M., Liu, H., Yang, S., Wang, J., Krasnoff, S. B., Xu, Y. & 2 others, Molnár, I. & Lin, M., Mar 15 2016, In : Scientific reports. 6, 23122.

Research output: Contribution to journalArticle

11 Scopus citations
2015

CYP287A1 is a carotenoid 2-β-hydroxylase required for deinoxanthin biosynthesis in Deinococcus radiodurans R1

Zhou, Z., Zhang, W., Su, S., Chen, M., Lu, W., Lin, M., Molnar, I. & Xu, Y., Dec 1 2015, In : Applied Microbiology and Biotechnology. 99, 24, p. 10539-10546 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Whole-genome optical mapping and finished genome sequence of sphingobacterium deserti sp. Nov., A new species isolated from the western desert of China

Teng, C., Zhou, Z., Molnár, I., Li, X., Tang, R., Chen, M., Wang, L., Su, S., Zhang, W. & Lin, M., Apr 1 2015, In : PloS one. 10, 4, e0122254.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases

Xu, Y., Zhou, T., Zhang, S., Espinosa-Artiles, P., Wang, L., Zhang, W., Lin, M., Gunatilaka, A. A. L., Zhan, J. & Molnár, I., Aug 26 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 34, p. 12354-12359 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Insights into the biosynthesis of 12-membered resorcylic acid lactones from heterologous production in saccharomyces cerevisiae

Xu, Y., Zhou, T., Espinosa-Artiles, P., Tang, Y., Zhan, J. & Molnár, I., May 16 2014, In : ACS Chemical Biology. 9, 5, p. 1119-1127 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
2013

Characterization of the biosynthetic genes for 10,11- dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus

Xu, Y., Espinosa-Artiles, P., Schubert, V., Xu, Y. M., Zhang, W., Lin, M., Leslie Gunatilaka, A. A., Süssmuth, R. & Molnár, I., Mar 1 2013, In : Applied and environmental microbiology. 79, 6, p. 2038-2047 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Rational reprogramming of fungal polyketide first-ring cyclization

Xu, Y., Zhou, T., Zhou, Z., Su, S., Roberts, S. A., Montfort, W. R., Zeng, J., Chen, M., Zhang, W., Lin, M., Zhan, J. & Molnár, I., Apr 2 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 14, p. 5398-5403 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Thioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis

Xu, Y., Zhou, T., Zhang, S., Xuan, L. J., Zhan, J. & Molnár, I., Jul 24 2013, In : Journal of the American Chemical Society. 135, 29, p. 10783-10791 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2012

Bio-crude transcriptomics: Gene discovery and metabolic network reconstruction for the biosynthesis of the terpenome of the hydrocarbon oil-producing green alga, Botryococcus braunii race B (Showa)

Molnár, I., Lopez, D., Wisecaver, J. H., Devarenne, T. P., Weiss, T. L., Pellegrini, M. & Hackett, J. D., Oct 30 2012, In : BMC genomics. 13, 1, 576.

Research output: Contribution to journalArticle

38 Scopus citations

In vitro chemoenzymatic and in vivo biocatalytic syntheses of new beauvericin analogues

Matthes, D., Richter, L., Müller, J., Denisiuk, A., Feifel, S. C., Xu, Y., Espinosa-Artiles, P., Süssmuth, R. D. & Molnár, I., May 9 2012, In : Chemical Communications. 48, 45, p. 5674-5676 3 p.

Research output: Contribution to journalArticle

27 Scopus citations

Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes

Gonzalez, D. J., Xu, Y., Yang, Y. L., Esquenazi, E., Liu, W. T., Edlund, A., Duong, T., Du, L., Molnár, I., Gerwick, W. H., Jensen, P. R., Fischbach, M., Liaw, C. C., Straight, P., Nizet, V. & Dorrestein, P. C., Aug 30 2012, In : Journal of Proteomics. 75, 16, p. 5069-5076 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011

Fungal cyclooligomer depsipeptides: From classical biochemistry to combinatorial biosynthesis

Süssmuth, R., Müller, J., Von Döhren, H. & Molnár, I., Jan 2011, In : Natural Product Reports. 28, 1, p. 99-124 26 p.

Research output: Contribution to journalReview article

53 Scopus citations
2010

Secondary metabolites from entomopathogenic Hypocrealean fungi

Molnár, I., Gibson, D. M. & Krasnoff, S. B., Sep 1 2010, In : Natural Product Reports. 27, 9, p. 1241-1275 35 p.

Research output: Contribution to journalReview article

134 Scopus citations
2009

Biosynthesis of the cyclooligomer depsipeptide bassianolide, an insecticidal virulence factor of Beauveria bassiana

Xu, Y., Orozco, R., Kithsiri Wijeratne, E. M., Espinosa-Artiles, P., Leslie Gunatilaka, A. A., Patricia Stock, S. & Molnár, I., May 1 2009, In : Fungal Genetics and Biology. 46, 5, p. 353-364 12 p.

Research output: Contribution to journalArticle

87 Scopus citations

Combinatorial mutasynthesis of scrambled beauvericins, cyclooligomer depsipeptide cell migration inhibitors from Beauveria bassiana

Xu, Y., Wijeratne, E. M. K., Espinosa-Artiles, P., Gunatilaka, A. A. L. & Molnár, I., Jan 26 2009, In : ChemBioChem. 10, 2, p. 345-354 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

The genome of Nectria haematococca: Contribution of supernumerary chromosomes to gene expansion

Coleman, J. J., Rounsley, S. D., Rodriguez-Carres, M., Kuo, A., Wasmann, C. C., Grimwood, J., Schmutz, J., Taga, M., White, G. J., Zhou, S., Schwartz, D. C., Freitag, M., Ma, L. J., Danchin, E. G. J., Henrissat, B., Coutinho, P. M., Nelson, D. R., Straney, D., Napoli, C. A., Barker, B. M. & 19 others, Gribskov, M., Rep, M., Kroken, S., Molnár, I., Rensing, C., Kennell, J. C., Zamora, J., Farman, M. L., Selker, E. U., Salamov, A., Shapiro, H., Pangilinan, J., Lindquist, E., Lamers, C., Grigoriev, I. V., Geiser, D. M., Covert, S. F., Temporini, E. & Vanetten, H. D., Aug 2009, In : PLoS genetics. 5, 8, e1000618.

Research output: Contribution to journalArticle

267 Scopus citations
2008

Biosynthesis of the Cyclooligomer Depsipeptide Beauvericin, a Virulence Factor of the Entomopathogenic Fungus Beauveria bassiana

Xu, Y., Orozco, R., Wijeratne, E. M. K., Gunatilaka, A. A. L., Stock, S. P. & Molnár, I., Sep 22 2008, In : Chemistry and Biology. 15, 9, p. 898-907 10 p.

Research output: Contribution to journalArticle

124 Scopus citations

Functional Characterization of the Biosynthesis of Radicicol, an Hsp90 Inhibitor Resorcylic Acid Lactone from Chaetomium chiversii

Wang, S., Xu, Y., Maine, E. A., Wijeratne, E. M. K., Espinosa-Artiles, P., Gunatilaka, A. A. L. & Molnár, I., Dec 22 2008, In : Chemistry and Biology. 15, 12, p. 1328-1338 11 p.

Research output: Contribution to journalArticle

79 Scopus citations
2007

Biocatalytic conversion of avermectin to 4″-oxo-avermectin: Improvement of cytochrome P450 monooxygenase specificity by directed evolution

Trefzer, A., Jungmann, V., Molnár, I., Botejue, A., Buckel, D., Frey, G., Hill, D. S., Jörg, M., Ligon, J. M., Mason, D., Moore, D., Pachlatko, J. P., Richardson, T. H., Spangenberg, P., Wall, M. A., Zirkle, R. & Stege, J. T., Jul 2007, In : Applied and environmental microbiology. 73, 13, p. 4317-4325 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Biosynthesis of the antifungal polyketide antibiotic soraphen A in Sorangium cellulosum and Streptomyces lividans

Molnár, I., Zirkle, R. & Ligón, J. M., Jan 1 2007, Polyketides Biosynthesis, Biological Activity, and Genetic Engineering. American Chemical Society, p. 217-230 14 p. (ACS Symposium Series; vol. 955).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Cytotoxic and antihaptotactic beauvericin analogues from precursor-directed biosynthesis with the insect pathogen Beauveria bassiana ATCC 7159

Xu, Y., Zhan, J., Wijeratne, E. M. K., Burns, A. M., Gunatilaka, A. A. L. & Molnár, I., Sep 1 2007, In : Journal Of Natural Products. 70, 9, p. 1467-1471 5 p.

Research output: Contribution to journalArticle

47 Scopus citations
2006

Biocatalytic conversion of avermectin into 4″-oxo-avermectin: Discovery, characterization, heterologous expression and specificity improvement of the cytochrome P450 enzyme

Molnár, I., Jungmann, V., Stege, J., Trefzer, A. & Pachlatko, J. P., Dec 1 2006, In : Biochemical Society transactions. 34, 6, p. 1236-1240 5 p.

Research output: Contribution to journalArticle

13 Scopus citations
2005

Biocatalytic conversion of avermectin to 4″-oxo-avermectin: Heterologous expression of the ema1 cytochrome p450 monooxygenase

Molnár, I., Hill, D. S., Zirkle, R., Hammer, P. E., Gross, F., Buckel, T. G., Jungmann, V., Pachlatko, J. P. & Ligon, J. M., Nov 1 2005, In : Applied and environmental microbiology. 71, 11, p. 6977-6985 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Biocatalytic conversion of avermectin to 4″-oxo-avermectin: Characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes

Jungmann, V., Molnár, I., Hammer, P. E., Hill, D. S., Zirkle, R., Buckel, T. G., Buckel, D., Ligon, J. M. & Pachlatko, J. P., Nov 2005, In : Applied and environmental microbiology. 71, 11, p. 6968-6976 9 p.

Research output: Contribution to journalArticle

26 Scopus citations
2004

Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus

Zirkle, R., Black, T. A., Gorlach, J., Ligon, J. M. & Molnár, I., Apr 1 2004, In : DNA Sequence - Journal of DNA Sequencing and Mapping. 15, 2, p. 123-134 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
3 Scopus citations

Heterologous production of the antifugal polyketide antibiotic soraphen A of Sorangium cellulosum So ce26 in Streptomyces lividans

Zirkle, R., Ligon, J. M. & Molnár, I., Aug 2004, In : Microbiology. 150, 8, p. 2761-2774 14 p.

Research output: Contribution to journalArticle

47 Scopus citations
2003

2,5-Dialkylresorcinol biosynthesis in Pseudomonas aurantiaca: Novel head-to-head condensation of two fatty acid-derived precursors

Nowak-Thompson, B., Hammer, P. E., Hill, D. S., Stafford, J., Torkewitz, N., Gaffney, T. D., Lam, S. T., Molnár, I. & Ligon, J. M., Feb 2003, In : Journal of bacteriology. 185, 3, p. 860-869 10 p.

Research output: Contribution to journalArticle

41 Scopus citations
2002

Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26

Ligon, J., Hill, S., Beck, J., Zirkle, R., Molnár, I., Zawodny, J., Money, S. & Schupp, T., Feb 20 2002, In : Gene. 285, 1-2, p. 257-267 11 p.

Research output: Contribution to journalArticle

78 Scopus citations
2000

The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90

Molnár, I., Schupp, T., Ono, M., Zirkle, R. E., Milnamow, M., Nowak-Thompson, B., Engel, N., Toupet, C., Stratmann, A., Cyr, D. D., Gorlach, J., Mayo, J. M., Hu, A., Goff, S., Schmid, J. & Ligon, J. M., Feb 1 2000, In : Chemistry and Biology. 7, 2, p. 97-109 13 p.

Research output: Contribution to journalArticle

257 Scopus citations
1997

The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin - Nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus

König, A., Schwecke, T., Molnár, I., Böhm, G. A., Lowden, P. A. S., Staunton, J. & Leadlay, P. F., Jan 1 1997, In : European Journal of Biochemistry. 247, 2, p. 526-534 9 p.

Research output: Contribution to journalArticle

51 Scopus citations
1996

Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: Analysis of genes flanking the polyketide synthase

Molnár, I., Aparicio, J. F., Haydock, S. F., Khaw, L. E., Schwecke, T., König, A., Staunton, J. & Leadlay, P. F., Feb 22 1996, In : Gene. 169, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: Analysis of the enzymatic domains in the modular polyketide synthase

Aparicio, J. F., Molnár, I., Schwecke, T., König, A., Haydock, S. F., Khaw, L. E., Staunton, J. & Leadlay, P. F., Feb 22 1996, In : Gene. 169, 1, p. 9-16 8 p.

Research output: Contribution to journalArticle

188 Scopus citations
1995

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

Haydock, S. F., Aparicio, J. F., Molnár, I., Schwecke, T., Khaw, L. E., König, A., Marsden, A. F. A., Galloway, I. S., Staunton, J. & Leadlay, P. F., Oct 30 1995, In : FEBS Letters. 374, 2, p. 246-248 3 p.

Research output: Contribution to journalArticle

202 Scopus citations