Projects per year
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- 7 Similar Profiles
Troponin T
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Familial Hypertrophic Cardiomyopathy
Medicine & Life Sciences
Hypertrophic Cardiomyopathy
Medicine & Life Sciences
Cardiomyopathies
Medicine & Life Sciences
Myofibrils
Medicine & Life Sciences
Tropomyosin
Medicine & Life Sciences
Sarcomeres
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2002 2020
A molecular study linking cTnT dynamics to genetic cardiomyopathy
Schwartz, S. D. & Tardiff, J. C.
12/15/10 → 2/29/20
Project: Research project › Research Project
Cardiomyopathies
Mutation
Familial Hypertrophic Cardiomyopathy
Phosphorylation
Biological Control Agents
Allele-specific Effects:Single Amino Acid Exchanges/cTnT
12/1/03 → 5/31/17
Project: Research project › Research Project
Mutation
Alleles
Troponin T
Amino Acids
Cardiomyopathies
Cellular Mechanisms in the Pathogenesis of FHC
3/1/02 → 2/28/07
Project: Research project › Clinical Investigator Award (CIA)
Familial Hypertrophic Cardiomyopathy
Troponin T
Mutation
Alleles
Cardiovascular Physiological Phenomena
Research Output 1988 2018
Biophysical Derangements in Genetic Cardiomyopathies
Lynn, M. L., Lehman, S. J. & Tardiff, J. C. Apr 1 2018 In : Heart Failure Clinics. 14, 2, p. 147-159 13 p.Research output: Contribution to journal › Review article
Calcium Signaling
Protein Stability
Cardiomyopathies
Myofibrils
Disease Progression
The Mechanism of Cardiac Tropomyosin Transitions on Filamentous Actin as Revealed by all Atom Steered Molecular Dynamics Simulations
Williams, M. R., Tardiff, J. C. & Schwartz, S. D. Mar 28 2018 (Accepted/In press) In : Journal of Physical Chemistry Letters.Research output: Contribution to journal › Article
Tropomyosin
Molecular dynamics
Actins
Atoms
Computer simulation
Assessing the phenotypic burden of preclinical sarcomeric hypertrophic cardiomyopathy - New assessments to guide diagnosis and management
Tardiff, J. C. Apr 1 2017 In : JAMA Cardiology. 2, 4, p. 428-429 2 p.Research output: Contribution to journal › Comment/debate
Hypertrophic Cardiomyopathy
2
Citations
Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac Tropomyosin Overlap
McConnell, M., Tal Grinspan, L., Williams, M. R., Lynn, M. L., Schwartz, B. A., Fass, O. Z., Schwartz, S. D. & Tardiff, J. C. Jul 5 2017 In : Biochemistry. 56, 26, p. 3403-3413 11 p.Research output: Contribution to journal › Article
Tropomyosin
Mutation
Sarcomeres
Troponin T
Dilated Cardiomyopathy
2
Citations
Pathogenesis of hypertrophic cardiomyopathy is mutation rather than disease specific: A comparison of the cardiac troponin T E163R and R92Q mouse models
Ferrantini, C., Coppini, R., Pioner, J. M., Gentile, F., Tosi, B., Mazzoni, L., Scellini, B., Piroddi, N., Laurino, A., Santini, L., Spinelli, V., Sacconi, L., De Tombe, P., Moore, R., Tardiff, J., Mugelli, A., Olivotto, I., Cerbai, E., Tesi, C. & Poggesi, C. Jul 1 2017 In : Journal of the American Heart Association. 6, 7, e005407Research output: Contribution to journal › Article
Troponin T
Myofibrils
Hypertrophic Cardiomyopathy
Excitation Contraction Coupling
Mutation