Jil C Tardiff

  • 2071 Citations
  • 22 h-Index
1988 …2020
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  • 8 Similar Profiles
Troponin T Medicine & Life Sciences
Mutation Medicine & Life Sciences
Familial Hypertrophic Cardiomyopathy Medicine & Life Sciences
Hypertrophic Cardiomyopathy Medicine & Life Sciences
Cardiomyopathies Medicine & Life Sciences
Sarcomeres Medicine & Life Sciences
Myofibrils Medicine & Life Sciences
Tropomyosin Medicine & Life Sciences

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Projects 2002 2020

Cardiomyopathies
Mutation
Familial Hypertrophic Cardiomyopathy
Phosphorylation
Biological Control Agents
Mutation
Alleles
Troponin T
Amino Acids
Cardiomyopathies

Cellular Mechanisms in the Pathogenesis of FHC

Tardiff, J. C.

National Institutes of Health

3/1/022/28/07

Project: Research projectClinical Investigator Award (CIA)

Familial Hypertrophic Cardiomyopathy
Troponin T
Mutation
Alleles
Cardiovascular Physiological Phenomena

Research Output 1988 2018

  • 2071 Citations
  • 22 h-Index
  • 50 Article
  • 2 Review article
  • 1 Comment/debate

Biophysical Derangements in Genetic Cardiomyopathies

Lynn, M. L., Lehman, S. J. & Tardiff, J. C., Apr 1 2018, In : Heart Failure Clinics. 14, 2, p. 147-159 13 p.

Research output: Contribution to journalReview article

Cardiomyopathies
Myofibrils
Disease Progression
Mutation
Therapeutics
1 Citations
Tropomyosin
myosins
Molecular dynamics
Actins
molecular dynamics
Hypertrophic Cardiomyopathy
4 Citations

Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac Tropomyosin Overlap

McConnell, M., Tal Grinspan, L., Williams, M. R., Lynn, M. L., Schwartz, B. A., Fass, O. Z., Schwartz, S. D. & Tardiff, J. C., Jul 5 2017, In : Biochemistry. 56, 26, p. 3403-3413 11 p.

Research output: Contribution to journalArticle

Tropomyosin
Mutation
Sarcomeres
Troponin T
Dilated Cardiomyopathy
5 Citations

Pathogenesis of hypertrophic cardiomyopathy is mutation rather than disease specific: A comparison of the cardiac troponin T E163R and R92Q mouse models

Ferrantini, C., Coppini, R., Pioner, J. M., Gentile, F., Tosi, B., Mazzoni, L., Scellini, B., Piroddi, N., Laurino, A., Santini, L., Spinelli, V., Sacconi, L., De Tombe, P., Moore, R., Tardiff, J. C., Mugelli, A., Olivotto, I., Cerbai, E., Tesi, C. & Poggesi, C., Jul 1 2017, In : Journal of the American Heart Association. 6, 7, e005407.

Research output: Contribution to journalArticle

Troponin T
Myofibrils
Hypertrophic Cardiomyopathy
Excitation Contraction Coupling
Mutation