Jil C Tardiff

  • 2287 Citations
  • 24 h-Index
1988 …2020
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Fingerprint Dive into the research topics where Jil C Tardiff is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Troponin T Medicine & Life Sciences
Mutation Medicine & Life Sciences
Hypertrophic Cardiomyopathy Medicine & Life Sciences
Familial Hypertrophic Cardiomyopathy Medicine & Life Sciences
Cardiomyopathies Medicine & Life Sciences
Sarcomeres Medicine & Life Sciences
Myofibrils Medicine & Life Sciences
Tropomyosin Medicine & Life Sciences

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Projects 2002 2020

Cardiomyopathies
Mutation
Familial Hypertrophic Cardiomyopathy
Phosphorylation
Biological Control Agents
Mutation
Alleles
Troponin T
Amino Acids
Cardiomyopathies
Familial Hypertrophic Cardiomyopathy
Troponin T
Mutation
Alleles
Cardiovascular Physiological Phenomena

Research Output 1988 2019

  • 2287 Citations
  • 24 h-Index
  • 54 Article
  • 3 Review article
  • 1 Comment/debate
1 Citation (Scopus)

Chronic Calmodulin-Kinase II Activation Drives Disease Progression in Mutation-Specific Hypertrophic Cardiomyopathy

Lehman, S. J., Tal-Grinspan, L., Lynn, M. L., Strom, J., Benitez, G. E., Anderson, M. E. & Tardiff, J. C., Mar 19 2019, In : Circulation. 139, 12, p. 1517-1529 13 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Hypertrophic Cardiomyopathy
Disease Progression
Calcium
Mutation

FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation

Abdullah, S., Lynn, M. L., McConnell, M. T., Klass, M. M., Baldo, A. P., Schwartz, S. D. & Tardiff, J. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 40, p. 14634-14647 14 p.

Research output: Contribution to journalArticle

Troponin T
Hypertrophic Cardiomyopathy
Actomyosin
Tropomyosin
Mutation
3 Citations (Scopus)
Sarcomeres
Cardiomyopathies
Hypertrophic Cardiomyopathy
Mutation
Proteins
1 Citation (Scopus)

Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations

Szatkowski, L., Lynn, M. L., Holeman, T., Williams, M. R., Baldo, A. P., Tardiff, J. C. & Schwartz, S. D., Apr 9 2019, In : ACS Omega. 4, 4, p. 6492-6501 10 p.

Research output: Contribution to journalArticle

Open Access
Molecular modeling
Molecules
Experiments
Docks
Animals
9 Citations (Scopus)

Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models

Vakrou, S., Fukunaga, R., Foster, D. B., Sorensen, L., Liu, Y., Guan, Y., Woldemichael, K., Pineda-Reyes, R., Liu, T., Tardiff, J. C., Leinwand, L. A., Tocchetti, C. G., Abraham, T. P., O'Rourke, B., Aon, M. A. & Abraham, M. R., Mar 22 2018, In : JCI insight. 3, 6

Research output: Contribution to journalArticle

Open Access
Hypertrophic Cardiomyopathy
Transcriptome
Alleles
Mutation
Antioxidants