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Jil C Tardiff

  • 2342 Citations
  • 25 h-Index
1988 …2020

Research output per year

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Projects

A New Paradigm to Incorporate Protein Dynamics into Targeted Small Molecule Design for Sarcomeric Cardiomyopathies: A Proof of Concept for Thin Filament Therapeutics

Schwartz, S. D. & Tardiff, J. C.

Project: Research project

Integrative Approaches to Complex Cardiovascular Diseases

Tardiff, J. C.

Project: Research project

A molecular study linking cTnT dynamics to genetic cardiomyopathy

Tardiff, J. C. & Schwartz, S. D.

National Institutes of Health

12/15/10 → 2/29/20

Project: Research project

    • Allele-specific Effects:Single Amino Acid Exchanges/cTnT

    Tardiff, J. C.

    National Institutes of Health

    12/1/03 → 5/31/17

    Project: Research project

    • Cellular Mechanisms in the Pathogenesis of FHC

    Tardiff, J. C.

    National Institutes of Health

    3/1/02 → 2/28/07

    Project: Research project

    • Research Output

    • 2342 Citations
    • 25 h-Index
    • 54 Article
    • 3 Review article
    • 1 Comment/debate

    Chronic Calmodulin-Kinase II Activation Drives Disease Progression in Mutation-Specific Hypertrophic Cardiomyopathy

    Lehman, S. J., Tal-Grinspan, L., Lynn, M. L., Strom, J., Benitez, G. E., Anderson, M. E. & Tardiff, J. C., Mar 19 2019, In : Circulation. 139, 12, p. 1517-1529 13 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation

    Abdullah, S., Lynn, M. L., McConnell, M. T., Klass, M. M., Baldo, A. P., Schwartz, S. D. & Tardiff, J. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 40, p. 14634-14647 14 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Moving beyond simple answers to complex disorders in sarcomeric cardiomyopathies: the role of integrated systems

    Deranek, A. E., Klass, M. M. & Tardiff, J. C., Jan 1 2019, In : Pflugers Archiv European Journal of Physiology.

    Research output: Contribution to journal › Review article

    • 4 Scopus citations

    Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations

    Szatkowski, L., Lynn, M. L., Holeman, T., Williams, M. R., Baldo, A. P., Tardiff, J. C. & Schwartz, S. D., Apr 9 2019, In : ACS Omega. 4, 4, p. 6492-6501 10 p.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Scopus citations

    Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models

    Vakrou, S., Fukunaga, R., Foster, D. B., Sorensen, L., Liu, Y., Guan, Y., Woldemichael, K., Pineda-Reyes, R., Liu, T., Tardiff, J. C., Leinwand, L. A., Tocchetti, C. G., Abraham, T. P., O'Rourke, B., Aon, M. A. & Abraham, M. R., Mar 22 2018, In : JCI insight. 3, 6

    Research output: Contribution to journal › Article

    Open Access
    • 10 Scopus citations