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Jil C Tardiff

  • 2407 Citations
  • 26 h-Index
1988 …2020

Research output per year

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Projects

Integrative Approaches to Complex Cardiovascular Diseases

Tardiff, J. C.

Project: Research project

A New Paradigm to Incorporate Protein Dynamics into Targeted Small Molecule Design for Sarcomeric Cardiomyopathies: A Proof of Concept for Thin Filament Therapeutics

Schwartz, S. D. & Tardiff, J. C.

Project: Research project

A molecular study linking cTnT dynamics to genetic cardiomyopathy

Tardiff, J. C. & Schwartz, S. D.

National Institutes of Health

12/15/10 → 2/29/20

Project: Research project

    • Allele-specific Effects:Single Amino Acid Exchanges/cTnT

    Tardiff, J. C.

    National Institutes of Health

    12/1/03 → 5/31/17

    Project: Research project

    • Cellular Mechanisms in the Pathogenesis of FHC

    Tardiff, J. C.

    National Institutes of Health

    3/1/02 → 2/28/07

    Project: Research project

    • Research Output

    • 2407 Citations
    • 26 h-Index
    • 48 Article
    • 10 Review article
    • 1 Comment/debate
    • 1 Editorial

    Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response

    Chowdhury, S. A. K., Warren, C. M., Simon, J. N., Ryba, D. M., Batra, A., Varga, P., Kranias, E. G., Tardiff, J. C., Solaro, R. J. & Wolska, B. M., Mar 10 2020, In : Frontiers in Physiology. 11, 107.

    Research output: Contribution to journal › Article

    Open Access

    • Chronic calmodulin-kinase II activation drives disease progression in mutation-specific hypertrophic cardiomyopathy

    Lehman, S. J., Tal-Grinspan, L., Lynn, M. L., Strom, J., Benitez, G. E., Anderson, M. E. & Tardiff, J. C., Jan 1 2019, In : Circulation. 139, 12, p. 1517-1529 13 p.

    Research output: Contribution to journal › Article

    • 5 Scopus citations

    Differences in microRNA-29 and Pro-fibrotic Gene Expression in Mouse and Human Hypertrophic Cardiomyopathy

    Liu, Y., Afzal, J., Vakrou, S., Greenland, G. V., Talbot, C. C., Hebl, V. B., Guan, Y., Karmali, R., Tardiff, J. C., Leinwand, L. A., Olgin, J. E., Das, S., Fukunaga, R. & Abraham, M. R., Dec 17 2019, In : Frontiers in Cardiovascular Medicine. 6, 170.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation

    Abdullah, S., Lynn, M. L., McConnell, M. T., Klass, M. M., Baldo, A. P., Schwartz, S. D. & Tardiff, J. C., Oct 4 2019, In : Journal of Biological Chemistry. 294, 40, p. 14634-14647 14 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Moving beyond simple answers to complex disorders in sarcomeric cardiomyopathies: the role of integrated systems

    Deranek, A. E., Klass, M. M. & Tardiff, J. C., Jan 1 2019, In : Pflugers Archiv European Journal of Physiology.

    Research output: Contribution to journal › Review article

    • 7 Scopus citations