Projects per year
Fingerprint Dive into the research topics where Jil C Tardiff is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Troponin T
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Hypertrophic Cardiomyopathy
Medicine & Life Sciences
Familial Hypertrophic Cardiomyopathy
Medicine & Life Sciences
Cardiomyopathies
Medicine & Life Sciences
Sarcomeres
Medicine & Life Sciences
Myofibrils
Medicine & Life Sciences
Tropomyosin
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2002 2020
A molecular study linking cTnT dynamics to genetic cardiomyopathy
Tardiff, J. C. & Schwartz, S. D.
12/15/10 → 2/29/20
Project: Research project
Cardiomyopathies
Mutation
Familial Hypertrophic Cardiomyopathy
Phosphorylation
Biological Control Agents
Mutation
Alleles
Troponin T
Amino Acids
Cardiomyopathies
Familial Hypertrophic Cardiomyopathy
Troponin T
Mutation
Alleles
Cardiovascular Physiological Phenomena
Research Output 1988 2019
1
Citation
(Scopus)
Chronic Calmodulin-Kinase II Activation Drives Disease Progression in Mutation-Specific Hypertrophic Cardiomyopathy
Lehman, S. J., Tal-Grinspan, L., Lynn, M. L., Strom, J., Benitez, G. E., Anderson, M. E. & Tardiff, J. C., Mar 19 2019, In : Circulation. 139, 12, p. 1517-1529 13 p.Research output: Contribution to journal › Article
Calcium-Calmodulin-Dependent Protein Kinases
Hypertrophic Cardiomyopathy
Disease Progression
Calcium
Mutation
1
Citation
(Scopus)
FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation
Abdullah, S., Lynn, M. L., McConnell, M. T., Klass, M. M., Baldo, A. P., Schwartz, S. D. & Tardiff, J. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 40, p. 14634-14647 14 p.Research output: Contribution to journal › Article
Troponin T
Hypertrophic Cardiomyopathy
Actomyosin
Tropomyosin
Mutation
3
Citations
(Scopus)
Moving beyond simple answers to complex disorders in sarcomeric cardiomyopathies: the role of integrated systems
Deranek, A. E., Klass, M. M. & Tardiff, J. C., Jan 1 2019, In : Pflugers Archiv European Journal of Physiology.Research output: Contribution to journal › Review article
Sarcomeres
Cardiomyopathies
Hypertrophic Cardiomyopathy
Mutation
Proteins
1
Citation
(Scopus)
Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations
Szatkowski, L., Lynn, M. L., Holeman, T., Williams, M. R., Baldo, A. P., Tardiff, J. C. & Schwartz, S. D., Apr 9 2019, In : ACS Omega. 4, 4, p. 6492-6501 10 p.Research output: Contribution to journal › Article
Open Access
Molecular modeling
Molecules
Experiments
Docks
Animals
9
Citations
(Scopus)
Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models
Vakrou, S., Fukunaga, R., Foster, D. B., Sorensen, L., Liu, Y., Guan, Y., Woldemichael, K., Pineda-Reyes, R., Liu, T., Tardiff, J. C., Leinwand, L. A., Tocchetti, C. G., Abraham, T. P., O'Rourke, B., Aon, M. A. & Abraham, M. R., Mar 22 2018, In : JCI insight. 3, 6Research output: Contribution to journal › Article
Open Access
Hypertrophic Cardiomyopathy
Transcriptome
Alleles
Mutation
Antioxidants