Projects per year
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- 6 Similar Profiles
Troponin T
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Familial Hypertrophic Cardiomyopathy
Medicine & Life Sciences
Hypertrophic Cardiomyopathy
Medicine & Life Sciences
Cardiomyopathies
Medicine & Life Sciences
Sarcomeres
Medicine & Life Sciences
Myofibrils
Medicine & Life Sciences
Tropomyosin
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2002 2020
A molecular study linking cTnT dynamics to genetic cardiomyopathy
Schwartz, S. D. & Tardiff, J. C.
12/15/10 → 2/29/20
Project: Research project
Cardiomyopathies
Mutation
Familial Hypertrophic Cardiomyopathy
Phosphorylation
Biological Control Agents
Mutation
Alleles
Troponin T
Amino Acids
Cardiomyopathies
Familial Hypertrophic Cardiomyopathy
Troponin T
Mutation
Alleles
Cardiovascular Physiological Phenomena
Research Output 1988 2019
1
Citation
(Scopus)
Chronic Calmodulin-Kinase II Activation Drives Disease Progression in Mutation-Specific Hypertrophic Cardiomyopathy
Lehman, S. J., Tal-Grinspan, L., Lynn, M. L., Strom, J., Benitez, G. E., Anderson, M. E. & Tardiff, J. C., Mar 19 2019, In : Circulation. 139, 12, p. 1517-1529 13 p.Research output: Contribution to journal › Article
Calcium-Calmodulin-Dependent Protein Kinases
Hypertrophic Cardiomyopathy
Disease Progression
Calcium
Mutation
1
Citation
(Scopus)
Moving beyond simple answers to complex disorders in sarcomeric cardiomyopathies: the role of integrated systems
Deranek, A. E., Klass, M. M. & Tardiff, J. C., Jan 1 2019, In : Pflugers Archiv European Journal of Physiology.Research output: Contribution to journal › Review article
Sarcomeres
Cardiomyopathies
Hypertrophic Cardiomyopathy
Mutation
Proteins
Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations
Szatkowski, L., Lynn, M. L., Holeman, T., Williams, M. R., Baldo, A. P., Tardiff, J. C. & Schwartz, S. D., Apr 9 2019, In : ACS Omega. 4, 4, p. 6492-6501 10 p.Research output: Contribution to journal › Article
Open Access
Molecular modeling
Molecules
Experiments
Docks
Animals
Biophysical Derangements in Genetic Cardiomyopathies
Lynn, M. L., Lehman, S. J. & Tardiff, J. C., Apr 1 2018, In : Heart Failure Clinics. 14, 2, p. 147-159 13 p.Research output: Contribution to journal › Review article
Cardiomyopathies
Myofibrils
Disease Progression
Mutation
Therapeutics
3
Citations
(Scopus)
The Mechanism of Cardiac Tropomyosin Transitions on Filamentous Actin as Revealed by all Atom Steered Molecular Dynamics Simulations
Williams, M. R., Tardiff, J. C. & Schwartz, S. D., Mar 28 2018, (Accepted/In press) In : Journal of Physical Chemistry Letters.Research output: Contribution to journal › Article
Tropomyosin
myosins
Molecular dynamics
Actins
molecular dynamics