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Joe GN Garcia

  • 26124 Citations
  • 85 h-Index
1976 …2021
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Endothelial Cells Medicine & Life Sciences
Endothelial cells Chemical Compounds
Lung Medicine & Life Sciences
Acute Lung Injury Medicine & Life Sciences
Myosin-Light-Chain Kinase Medicine & Life Sciences
Thrombin Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Endothelium Medicine & Life Sciences

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Projects 1976 2021

Cytoskeletal Regulation of Lung Endothelial Pathobiology

Lussier, Y. A. & Garcia, J. G.

National Institutes of Health

6/1/16 → 3/31/21

Project: Research project › Research Program Projects

Endothelial Cells
Focal Adhesions
Adult Respiratory Distress Syndrome
Paxillin
Integrins

Regulation of nonmuscle myosin light chain kinase structure and function of ARDS

Garcia, J. G.

National Institutes of Health

12/16/15 → 11/30/19

Project: Research project › Research Project

Myosin-Light-Chain Kinase
Adult Respiratory Distress Syndrome
Single Nucleotide Polymorphism
Ventilator-Induced Lung Injury
Endothelial Cells

Regulation of Asthmatic Inflammation by Non-Muscle MLCK

Garcia, J. G. & Wang, T.

National Institutes of Health

9/1/08 → 3/31/19

Project: Research project › Research Project

Myosin-Light-Chain Kinase
Asthma
Inflammation
Single Nucleotide Polymorphism
Protein Isoforms

CHARACTERIZATION OF THE HEME-BINDING SITE IN HEMOPEXIN

Garcia, J. G., Menkes, H. A., Burke, T., Sylvester, J., Wise, R. A., King, L. & Lukat, G.

National Institutes of Health

7/1/82 → …

Project: Research project › Postdoctoral Individual National Research Service Award, Institutional National Research Service Award

Lung Diseases
Education
Research
Public Health Schools
Behavioral Sciences

Genetics, Epigenetics, and Post-translational Modifications and the Development of Ventilator-Induced Lung Injury (VILI)

Garcia, J. G., Yuan, J. & Wang, T.

Project: Research project

Research Output 1984 2018

1 Citations

A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis

Rosas, I. O., Goldberg, H. J., Collard, H. R., El-Chemaly, S., Flaherty, K., Hunninghake, G. M., Lasky, J. A., Lederer, D. J., Machado, R., Martinez, F. J., Maurer, R., Teller, D., Noth, I., Peters, E., Raghu, G., Garcia, J. G. N. & Choi, A. M. K., Jan 1 2018, In : Chest. 153, 1, p. 94-104 11 p.

Research output: Contribution to journal › Article

Idiopathic Pulmonary Fibrosis
Phase II Clinical Trials
Carbon Monoxide
Matrix Metalloproteinase 7
Therapeutics
1 Citations

Diabetes Mellitus Associates with Increased Right Ventricular Afterload and Remodeling in Pulmonary Arterial Hypertension

Whitaker, M. E., Nair, V., Sinari, S., Dherange, P. A., Natarajan, B., Trutter, L., Brittain, E. L., Hemnes, A. R., Austin, E. D., Patel, K., Black, S. M., Garcia, J. G. N., Yuan, MD PhD, J. X., Vanderpool, R. R., Rischard, F., Makino, A., Bedrick, E. J. & Desai, A. A., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journal › Article

Ventricular Remodeling
Pulmonary Hypertension
Diabetes Mellitus
Right Ventricular Dysfunction
Glycosylated Hemoglobin A
6 Citations

Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition

Tang, H. , Babicheva, A. , McDermott, K. M. , Gu, Y. , Ayon, R. J. , Song, S. , Wang, Z. , Gupta, A. , Zhou, T. , Sun, X. , Dash, S. , Wang, Z. , Balistrieri, A. , Zheng, Q. , Cordery, A. G. , Desai, A. A. , Rischard, F. , Khalpey, Z. , Wang, J. , Black, S. M. & 3 others Garcia, J. G. N., Makino, A. & Yuan, J. X. J., Feb 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 2, p. L256-L275

Research output: Contribution to journal › Article

Pulmonary Hypertension
Endothelial Cells
Lung
Prolyl Hydroxylases
Smooth Muscle Myocytes
1 Citations

Genome-wide association study in African Americans with acute respiratory distress syndrome identifies the selectin P ligand gene as a risk factor

Bime, C. , Pouladi, N. , Sammani, S. , Batai, K. , Casanova, N. , Zhou, T. , Kempf, C. L. , Sun, X. , Camp, S. M. , Wang, T. , Kittles, R. A. , Lussier, Y. A. , Jones, T. K. , Reilly, J. P. , Meyer, N. J. , Christie, J. D. , Karnes, J. H. , Gonzalez-Garay, M. , Christiani, D. C. , Yates, C. R. & 3 others Wurfel, M. M., Meduri, G. U. & Garcia, J. G. N., Jun 1 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 11, p. 1421-1432 12 p.

Research output: Contribution to journal › Article

P-Selectin
Genome-Wide Association Study
Adult Respiratory Distress Syndrome
African Americans
Ligands
3 Citations

LPS-induced acute lung injury involves NF-kB–mediated downregulation of SOX18

Gross, C. M. , Kellner, M. , Wang, T. , Lu, Q. , Sun, X. , Zemskov, E. A. , Noonepalle, S. , Kangath, A. , Kumar, S. , Gonzalez-Garay, M. , Desai, A. A. , Aggarwal, S. , Gorshkov, B. , Klinger, C. , Verin, A. D. , Catravas, J. D. , Jacobson, J. R. , Yuan, J. X. J. , Rafikov, R. , Garcia, J. G. N. & 1 others Black, S. M., May 1 2018, In : American Journal of Respiratory Cell and Molecular Biology. 58, 5, p. 614-624 11 p.

Research output: Contribution to journal › Article

NF-kappa B
Acute Lung Injury
Down-Regulation
Lung
Endothelial Cells