Projects per year
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- 2 Similar Profiles
Adrenergic Receptors
Medicine & Life Sciences
Prostaglandins
Medicine & Life Sciences
Prostaglandins E
Medicine & Life Sciences
Prostaglandins F
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Organism Cloning
Medicine & Life Sciences
Prostaglandin Receptors
Medicine & Life Sciences
Protein Isoforms
Medicine & Life Sciences
Network
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Projects 1991 2008
- 2 Finished
ALPHA 2 AND PROSTAGLANDIN RECEPTORS IN EYE
4/1/97 → 3/31/08
Project: Research project › Research Project
Prostaglandin Receptors
Aquaporin 1
Aquaporins
Epithelium
Protein Isoforms
Mutagenesis
Adrenergic Receptors
Organism Cloning
varespladib methyl
Adrenergic Agents
Research Output 1974 2017
Anti-cancer effects of MW-03, a novel indole compound, by inducing 15-hydroxyprostaglandin dehydrogenase and cellular growth inhibition in the ls174t human colon cancer cell line
Seira, N., Yanagisawa, N., Suganami, A., Honda, T., Wasai, M., Regan, J. W., Fukushima, K., Yamaguchi, N., Tamura, Y., Arai, T., Murayama, T. & Fujino, H. 2017 In : Biological and Pharmaceutical Bulletin. 40, 10, p. 1806-1812 7 p.Research output: Contribution to journal › Article
15-hydroxyprostaglandin dehydrogenase
Colonic Neoplasms
Prostaglandins E
Cell Line
Growth
PGE1 and E3 show lower efficacies than E2 to β-catenin-mediated activity as biased ligands of EP4 prostanoid receptors
Araki, Y., Suganami, A., Endo, S., Masuda, Y., Fukushima, K., Regan, J. W., Murayama, T., Tamura, Y. & Fujino, H. 2017 (Accepted/In press) In : FEBS Letters.Research output: Contribution to journal › Article
Receptors, Prostaglandin E, EP4 Subtype
beta Catenin
Prostaglandins E
Ligands
Prostaglandins
1
Citations
Human DP and EP2 prostanoid receptors take on distinct forms depending on the diverse binding of different ligands
Suganami, A., Fujino, H., Okura, I., Yanagisawa, N., Sugiyama, H., Regan, J. W., Tamura, Y. & Murayama, T. Nov 1 2016 In : FEBS Journal. 283, 21, p. 3931-3940 10 p.Research output: Contribution to journal › Article
Prostaglandins
Ligands
Prostaglandins E
Prostaglandins D
Prostaglandins F
4
Citations
Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1α in HCA-7 human colon cancer cells
Otake, S., Yoshida, K., Seira, N., Sanchez, C. M., Regan, J. W., Fujino, H. & Murayama, T. Feb 1 2015 In : Pharmacology Research and Perspectives. 3, 1, p. 1-13 13 p.Research output: Contribution to journal › Article
Prostaglandins E
Colonic Neoplasms
Prostaglandins
Cyclooxygenase 2
Up-Regulation
5
Citations
Prostaglandin E2-stimulated prostanoid EP4 receptors induce prolonged de novo prostaglandin E2 synthesis through biphasic phosphorylation of extracellular signal-regulated kinases mediated by activation of protein kinase A in HCA-7 human colon cancer cells
Fujino, H., Seira, N., Kurata, N., Araki, Y., Nakamura, H., Regan, J. W. & Murayama, T. Dec 5 2015 In : European Journal of Pharmacology. 768, p. 149-159 11 p.Research output: Contribution to journal › Article
Extracellular Signal-Regulated MAP Kinases
Cyclic AMP-Dependent Protein Kinases
Prostaglandins E
Colonic Neoplasms
Prostaglandins