• 5196 Citations
  • 33 h-Index
19942019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 5196 Citations
  • 33 h-Index
  • 65 Article
  • 8 Review article
  • 3 Comment/debate
1994

A facile synthesis of α-phosphono esters through methoxycarbonylation of α-phosphono carbanions

Geirsson, J. K. F. & Njardarson, J. T., Nov 28 1994, In : Tetrahedron Letters. 35, 48, p. 9071-9072 2 p.

Research output: Contribution to journalArticle

3 Scopus citations
2001

An expeditious approach toward the total synthesis of CP-263,114

Njardarson, J. T., McDonald, I. M., Spiegel, D. A., Inoue, M. & Wood, J. L., Aug 9 2001, In : Organic Letters. 3, 16, p. 2435-2438 4 p.

Research output: Contribution to journalArticle

49 Scopus citations

Evolution of a synthetic approach to CP-263,114

Njardarson, J. T. & Wood, J. L., Aug 9 2001, In : Organic Letters. 3, 16, p. 2431-2434 4 p.

Research output: Contribution to journalArticle

44 Scopus citations
2002

Application of hitherto unexplored macrocyclization strategies in the epothilone series: novel epothilone analogs by total synthesis

Njardarson, J. T., Biswas, K. & Danishefsky, S. J., Jan 1 2002, In : Chemical Communications. 2, 23, p. 2759-2761 3 p.

Research output: Contribution to journalArticle

47 Scopus citations

CP-263,114 synthetic studies. Construction of an isotwistane ring system via rhodium carbenoid C-H insertion

Spiegel, D. A., Njardarson, J. T. & Wood, J. L., Aug 5 2002, In : Tetrahedron. 58, 32, p. 6545-6554 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Highly concise routes to epothilones: The total synthesis and evaluation of epothilone 490

Biswas, K., Lin, H., Njardarson, J. T., Chappell, M. D., Chou, T. C., Guan, Y., Tong, W. P., He, L., Horwitz, S. B. & Danishefsky, S. J., Aug 21 2002, In : Journal of the American Chemical Society. 124, 33, p. 9825-9832 8 p.

Research output: Contribution to journalArticle

100 Scopus citations

Reactive dienes: Intramolecular aromatic oxidation of 3-(2-hydroxyphenyl)-propionic acids

Drutu, I., Njardarson, J. T. & Wood, J. L., Feb 21 2002, In : Organic Letters. 4, 4, p. 493-496 4 p.

Research output: Contribution to journalArticle

67 Scopus citations
46 Scopus citations
2003

Application of phenolic oxidation chemistry in synthesis: Preparation of the BCE ring system of ryanodine

Wood, J. L., Graeber, J. K. & Njardarson, J. T., Nov 3 2003, In : Tetrahedron. 59, 45, p. 8855-8858 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

The art of innovation in organic chemistry: Synthetic efforts toward the phomoidrides

Spiegel, D. A., Njardarson, J. T., McDonald, I. M. & Wood, J. L., Jul 1 2003, In : Chemical Reviews. 103, 7, p. 2691-2727 37 p.

Research output: Contribution to journalReview article

42 Scopus citations

The total synthesis of (+)-migrastatin

Gaul, C., Njardarson, J. T. & Danishefsky, S. J., May 21 2003, In : Journal of the American Chemical Society. 125, 20, p. 6042-6043 2 p.

Research output: Contribution to journalArticle

90 Scopus citations
2004

Discovery of Potent Cell Migration Inhibitors through Total Synthesis: Lessons from Structure-Activity Studies of (+)-Migrastatin

Njardarson, J. T., Gaul, C., Shan, D., Huang, X. Y. & Danishefsky, S. J., Feb 4 2004, In : Journal of the American Chemical Society. 126, 4, p. 1038-1040 3 p.

Research output: Contribution to journalArticle

156 Scopus citations

The migrastatin family: Discovery of potent cell migration inhibitors by chemical synthesis

Gaul, C., Njardarson, J. T., Shan, D., Dorn, D. C., Wu, K. D., Tong, W. P., Huang, X. Y., Moore, M. A. S. & Danishefsky, S. J., Sep 15 2004, In : Journal of the American Chemical Society. 126, 36, p. 11326-11337 12 p.

Research output: Contribution to journalArticle

148 Scopus citations
2005

Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice

Shan, D., Chen, L., Njardarson, J. T., Gaul, C., Ma, X., Danishefsky, S. J. & Huang, X. Y., Mar 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 10, p. 3772-3776 5 p.

Research output: Contribution to journalArticle

135 Scopus citations
2006

Copper-catalyzed rearrangement of vinyl oxiranes

Batory, L. A., McInnis, C. E. & Njardarson, J. T., Dec 20 2006, In : Journal of the American Chemical Society. 128, 50, p. 16054-16055 2 p.

Research output: Contribution to journalArticle

53 Scopus citations
2007

Highly selective copper-catalyzed ring expansion of vinyl thiiranes: Application to synthesis of biotin and the heterocyclic core of plavix

Rogers, E., Araki, H., Batory, L. A., McInnis, C. E. & Njardarson, J. T., Mar 14 2007, In : Journal of the American Chemical Society. 129, 10, p. 2768-2769 2 p.

Research output: Contribution to journalArticle

47 Scopus citations

PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice

McDevitt, M. R., Chattopadhyay, D., Jaggi, J. S., Finn, R. D., Zanzonico, P. B., Villa, C., Rey, D., Mendenhall, J., Batt, C. A., Njardarson, J. T. & Scheinberg, D. A., Sep 19 2007, In : PloS one. 2, 9, e907.

Research output: Contribution to journalArticle

140 Scopus citations

Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes

McDevitt, M. R., Chattopadhyay, D., Kappel, B. J., Jaggi, J. S., Schiffman, S. R., Antczak, C., Njardarson, J. T., Brentjens, R. & Scheinberg, D. A., Jul 1 2007, In : Journal of Nuclear Medicine. 48, 7, p. 1180-1189 10 p.

Research output: Contribution to journalArticle

351 Scopus citations
2008

An efficient substrate-controlled approach towards hypoestoxide, a member of a family of diterpenoid natural products with an inside-out [9.3.1]bicyclic core

McGrath, N. A., Lee, C. A., Araki, H., Brichacek, M. & Njardarson, J. T., Nov 24 2008, In : Angewandte Chemie - International Edition. 47, 49, p. 9450-9453 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Lewis acid catalyzed [1,3]-sigmatropic rearrangement of vinyl aziridines

Brichacek, M., Lee, D. & Njardarson, J. T., Dec 1 2008, In : Organic Letters. 10, 21, p. 5023-5026 4 p.

Research output: Contribution to journalArticle

64 Scopus citations
2009

A concise ring-expansion route to the compact core of platensimycin

McGrath, N. A., Bartlett, E. S., Sittihan, S. & Njardarson, J. T., Oct 26 2009, In : Angewandte Chemie - International Edition. 48, 45, p. 8543-8546 4 p.

Research output: Contribution to journalArticle

64 Scopus citations

An Adler-Becker oxidation approach to vinigrol

Morton, J. G. M., Kwon, L. D., Freeman, J. D. & Njardarson, J. T., Apr 15 2009, In : Tetrahedron Letters. 50, 15, p. 1684-1686 3 p.

Research output: Contribution to journalArticle

25 Scopus citations
68 Scopus citations

Rapid assembly of vinigrol's unique carbocyclic skeleton

Morton, J. G. M., Draghici, C., Kwon, L. D. & Njardarson, J. T., Oct 15 2009, In : Organic Letters. 11, 20, p. 4492-4495 4 p.

Research output: Contribution to journalArticle

46 Scopus citations

Thieme Chemistry Journal awardees - Where are they now? Efforts towards the total synthesis of vinigrol

Morton, J. G. M., Kwon, L. D., Freeman, J. D. & Njardarson, J. T., Jan 1 2009, In : Synlett. 1, p. 23-27 5 p.

Research output: Contribution to journalArticle

25 Scopus citations
2010

A graphical journey of innovative organic architectures that have improved our lives

McGrath, N. A., Brichacek, M. & Njardarson, J. T., Dec 1 2010, In : Journal of Chemical Education. 87, 12, p. 1348-1349 2 p.

Research output: Contribution to journalComment/debate

341 Scopus citations

Confirmation of the structures of synthetic derivatives of migrastatin in the light of recently disclosed crystallographically based claims

Nagorny, P., Krauss, I., Njardarson, J. T., Perez, L., Gaul, C., Yang, G., Ouerfelli, O. & Danishefsky, S. J., Jul 28 2010, In : Tetrahedron Letters. 51, 30, p. 3873-3875 3 p.

Research output: Contribution to journalArticle

16 Scopus citations

Stereoselective ring expansion of vinyl oxiranes: Mechanistic insights and natural product total synthesis

Brichacek, M., Batory, L. A. & Njardarson, J. T., Feb 22 2010, In : Angewandte Chemie - International Edition. 49, 9, p. 1648-1651 4 p.

Research output: Contribution to journalArticle

35 Scopus citations

The strategic marriage of method and motif. Total synthesis of varitriol

Brichacek, M., Batory, L. A., McGrath, N. A. & Njardarson, J. T., Jun 26 2010, In : Tetrahedron. 66, 26, p. 4832-4840 9 p.

Research output: Contribution to journalArticle

33 Scopus citations
2011

An efficient oxidative dearomatization-radical cyclization approach to symmetrically substituted bicyclic guttiferone natural products

McGrath, N. A., Binner, J. R., Markopoulos, G., Brichacek, M. & Njardarson, J. T., Jan 7 2011, In : Chemical Communications. 47, 1, p. 209-211 3 p.

Research output: Contribution to journalArticle

25 Scopus citations

Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin

Lecomte, N., Njardarson, J. T., Nagorny, P., Yang, G., Downey, R., Ouerfelli, O., Moore, M. A. S. & Danishefsky, S. J., Sep 13 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 37, p. 15074-15078 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

Stereospecific ring expansion of chiral vinyl aziridines

Brichacek, M., Navarro Villalobos, M., Plichta, A. & Njardarson, J. T., Mar 4 2011, In : Organic Letters. 13, 5, p. 1110-1113 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

Synthetic efforts toward [3.3.1] bridged bicyclic phloroglucinol natural products

Njardarson, J. T., Oct 7 2011, In : Tetrahedron. 67, 40, p. 7631-7666 36 p.

Research output: Contribution to journalReview article

64 Scopus citations
2012

Catalytic ring expansion of vinyl oxetanes: Asymmetric synthesis of dihydropyrans using chiral counterion catalysis

Guo, B., Schwarzwalder, G. & Njardarson, J. T., Jun 4 2012, In : Angewandte Chemie - International Edition. 51, 23, p. 5675-5678 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

Chemistry by design: A web-based educational flashcard for exploring synthetic organic chemistry

Draghici, C. & Njardarson, J. T., Jul 10 2012, In : Journal of Chemical Education. 89, 8, p. 1080-1082 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

Distinct biological effects of golgicide a derivatives on larval and adult mosquitoes

MacK, D. J., Isoe, J., Miesfeld, R. L. & Njardarson, J. T., Aug 15 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 16, p. 5177-5181 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Efficient synthesis of thiopyrans using a sulfur-enabled anionic cascade

Li, F., Calabrese, D., Brichacek, M., Lin, I. & Njardarson, J. T., Feb 20 2012, In : Angewandte Chemie - International Edition. 51, 8, p. 1938-1941 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Intermolecular oxonium ylide mediated synthesis of medium-sized oxacycles

MacK, D. J., Batory, L. A. & Njardarson, J. T., Jan 6 2012, In : Organic Letters. 14, 1, p. 378-381 4 p.

Research output: Contribution to journalArticle

29 Scopus citations
29 Scopus citations

Synthesis of allylic and homoallylic alcohols from unsaturated cyclic ethers using a mild and selective C-O reduction approach

Mack, D. J., Guo, B. & Njardarson, J. T., Jul 11 2012, In : Chemical Communications. 48, 63, p. 7844-7846 3 p.

Research output: Contribution to journalArticle

33 Scopus citations
2013

An In-pharm-ative educational poster anthology highlighting the therapeutic agents that chronicle our medicinal history

Ilardi, E. A., Vitaku, E. & Njardarson, J. T., Oct 8 2013, In : Journal of Chemical Education. 90, 10, p. 1403-1405 3 p.

Research output: Contribution to journalArticle

28 Scopus citations

Base mediated deprotection strategies for trifluoroethyl (TFE) ethers, a new alcohol protecting group

Yang, Q. & Njardarson, J. T., Dec 18 2013, In : Tetrahedron Letters. 54, 51, p. 7080-7082 3 p.

Research output: Contribution to journalArticle

12 Scopus citations

Catalytic ring expansion adventures

Njardarson, J. T., Mar 15 2013, In : Synlett. 24, 7, p. 787-803 17 p., ST-2013-A0056-A.

Research output: Contribution to journalArticle

20 Scopus citations

Mechanism and the origins of stereospecificity in copper-catalyzed ring expansion of vinyl oxiranes: A traceless dual transition-metal-mediated process

Mustard, T. J. L., MacK, D. J., Njardarson, J. T. & Cheong, P. H. Y., Jan 30 2013, In : Journal of the American Chemical Society. 135, 4, p. 1471-1475 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Recent advances in the metal-catalyzed ring expansions of three- and four-membered rings

MacK, D. J. & Njardarson, J. T., Feb 1 2013, In : ACS Catalysis. 3, 2, p. 272-286 15 p.

Research output: Contribution to journalReview article

160 Scopus citations
58 Scopus citations
18 Scopus citations

Total synthesis of vinigrol

Yang, Q., Njardarson, J. T., Draghici, C. & Li, F., Aug 12 2013, In : Angewandte Chemie - International Edition. 52, 33, p. 8648-8651 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

Z-Selective ring opening of vinyl oxetanes with dialkyl dithiophosphate nucleophiles

Guo, B. & Njardarson, J. T., Oct 24 2013, In : Chemical Communications. 49, 92, p. 10802-10804 3 p.

Research output: Contribution to journalArticle

16 Scopus citations
2014

Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticals

Vitaku, E., Smith, D. T. & Njardarson, J. T., Dec 26 2014, In : Journal of Medicinal Chemistry. 57, 24, p. 10257-10274 18 p.

Research output: Contribution to journalArticle

1313 Scopus citations