Jui-Cheng Hsieh

  • 4865 Citations
  • 31 h-Index
1987 …2019

Research output per year

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Research Output

  • 4865 Citations
  • 31 h-Index
  • 49 Article
  • 2 Chapter
  • 2 Review article
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Article
2019

Hairless regulates p53 target genes to exert tumor suppressive functions in glioblastoma

Brook, L., Palade, P., Maatough, A., Whitfield, G. K., Emeterio, L. S., Hsieh, D. & Hsieh, J. C., Jan 2019, In : Journal of Cellular Biochemistry. 120, 1, p. 533-543 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers

Maatough, A., Whitfield, G. K., Brook, L., Hsieh, D., Palade, P. & Hsieh, J-C., 2017, (Accepted/In press) In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticle

4 Scopus citations

The Mammalian Hairless Protein as a DNA Binding Phosphoprotein

Brook, L., Whitfield, G. K., Hsieh, D., Bither, R. D. & Hsieh, J-C., Feb 1 2017, In : Journal of Cellular Biochemistry. 118, 2, p. 341-350 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

1,25-Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: implication for behavioral influences of vitamin D

Kaneko, I., Sabir, M. S., Dussik, C. M., Whitfield, G. K., Karrys, A., Hsieh, J-C., Haussler, M. R., Meyer, M. B., Pike, J. W. & Jurutka, P. W., Sep 1 2015, In : FASEB Journal. 29, 9, p. 4023-4035 13 p.

Research output: Contribution to journalArticle

56 Scopus citations
2014

Identification of two novel functional p53 responsive elements in the herpes simplex virus-1 genome

Hsieh, J. C., Kuta, R., Armour, C. R. & Boehmer, P. E., Jul 2014, In : Virology. 460-461, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes

Hsieh, J. C., Estess, R. C., Kaneko, I., Kerr Whitfield, G., Jurutka, P. W. & Haussler, M. R., Feb 1 2014, In : Journal of Endocrinology. 220, 2, p. 165-178 14 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013
49 Scopus citations

Molecular mechanisms of vitamin D action

Haussler, M. R., Whitfield, G. K., Kaneko, I., Haussler, C. A., Hsieh, D., Hsieh, J. C. & Jurutka, P. W., Jan 1 2013, In : Calcified Tissue International. 92, 2, p. 77-98 22 p.

Research output: Contribution to journalArticle

350 Scopus citations
2011

Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells

Forster, R. E., Jurutka, P. W., Hsieh, J. C., Haussler, C. A., Lowmiller, C. L., Kaneko, I., Haussler, M. R. & Kerr Whitfield, G., Oct 28 2011, In : Biochemical and Biophysical Research Communications. 414, 3, p. 557-562 6 p.

Research output: Contribution to journalArticle

93 Scopus citations
2010

Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle

Hsieh, J. C., Slater, S. A., Whitfield, G. K., Dawson, J. L., Hsieh, G., Sheedy, C., Haussler, C. A. & Haussler, M. R., Jun 1 2010, In : Journal of Cellular Biochemistry. 110, 3, p. 671-686 16 p.

Research output: Contribution to journalArticle

21 Scopus citations

The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the " Fountain of Youth" to mediate healthful aging

Haussler, M. R., Haussler, C. A., Whitfield, G. K., Hsieh, J. C., Thompson, P. D., Barthel, T. K., Bartik, L., Egan, J. B., Wu, Y., Kubicek, J. L., Lowmiller, C. L., Moffet, E. W., Forster, R. E. & Jurutka, P. W., Jul 1 2010, In : Journal of Steroid Biochemistry and Molecular Biology. 121, 1-2, p. 88-97 10 p.

Research output: Contribution to journalArticle

123 Scopus citations
2008

Vitamin D receptor: Molecular signaling and actions of nutritional ligands in disease prevention

Haussler, M. R., Haussler, C. A., Bartik, L., Whitfield, G. K., Hsieh, J. C., Slater, S. & Jurutka, P. W., Oct 1 2008, In : Nutrition reviews. 66, SUPPL.2, p. S98-S112

Research output: Contribution to journalArticle

205 Scopus citations
2007

1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism

Barthel, T. K., Mathern, D. R., Whitfield, G. K., Haussler, C. A., Hopper IV, H. A., Hsieh, J. C., Slater, S. A., Hsieh, G., Kaczmarska, M., Jurutka, P. W., Kolek, O. I., Ghishan, F. K. & Haussler, M. R., Mar 1 2007, In : Journal of Steroid Biochemistry and Molecular Biology. 103, 3-5, p. 381-388 8 p.

Research output: Contribution to journalArticle

121 Scopus citations

Vitamin D receptor: Key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands

Jurutka, P. W., Bartik, L., Whitfield, G. K., Mathern, D. R., Barthel, T. K., Gurevich, M., Hsieh, J. C., Kaczmarska, M., Haussler, C. A. & Haussler, M. R., Dec 1 2007, In : Journal of Bone and Mineral Research. 22, SUPPL. 2, p. V2-V10

Research output: Contribution to journalArticle

100 Scopus citations
2005

Molecular and functional comparison of 1,25-dihydroxyvitamin D3 and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4

Jurutka, P. W., Thompson, P. D., Whitfield, G. K., Eichhorst, K. R., Hall, N., Dominguez, C. E., Hsieh, J. C., Haussler, C. A. & Haussler, M. R., Apr 1 2005, In : Journal of Cellular Biochemistry. 94, 5, p. 917-943 27 p.

Research output: Contribution to journalArticle

69 Scopus citations
2004

Phosphorylation of human vitamin D receptor serine-182 by PKA suppresses 1,25(OH)2D3-dependent transactivation

Hsieh, J. C., Dang, H. T. L., Galligan, M. A., Whitfield, G. K., Haussler, C. A., Jurutka, P. W. & Haussler, M. R., Nov 12 2004, In : Biochemical and Biophysical Research Communications. 324, 2, p. 801-809 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2003

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling

Hsieh, J. C., Sisk, J. M., Jurutka, P. W., Haussler, C. A., Slater, S. A., Haussler, M. R. & Thompson, C. C., Oct 3 2003, In : Journal of Biological Chemistry. 278, 40, p. 38665-38674 10 p.

Research output: Contribution to journalArticle

174 Scopus citations

Two Basic Amino Acids C-Terminal of the Proximal Box Specify Functional Binding of the Vitamin D Receptor to Its Rat Osteocalcin Deoxyribonucleic Acid-Responsive Element

Hsieh, J. C., Whitfield, G. K., Jurutka, P. W., Haussler, C. A., Thatcher, M. L., Thompson, P. D., Dang, H. T. L., Galligan, M. A., Oza, A. K. & Haussler, M. R., Nov 1 2003, In : Endocrinology. 144, 11, p. 5065-5080 16 p.

Research output: Contribution to journalArticle

15 Scopus citations
2002

Isolation of baculovirus-expressed human vitamin D receptor: DNA responsive element interactions and phosphorylation of the purified receptor

Jurutka, P. W., MacDonald, P. N., Nakajima, S., Hsieh, J. C., Thompson, P. D., Kerr Whitfield, G., Galligan, M. A., Haussler, C. A. & Haussler, M. R., Apr 15 2002, In : Journal of Cellular Biochemistry. 85, 2, p. 435-457 23 p.

Research output: Contribution to journalArticle

34 Scopus citations

The nuclear vitamin D receptor: From clinical radioreceptor assay of the vitamin D hormone to genomics, proteomics and a novel ligand

Haussler, M. R., Haussler, C. A., Jurutka, P. W., Encinas Dominguez, C., Hsieh, J. C., Thatcher, M. L. & Whitfield, G. K., Jun 1 2002, In : Journal of Clinical Ligand Assay. 25, 2, p. 221-228 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2001

Distinct retinoid X receptor activation function-2 residues mediate transactivation in homodimeric and vitamin D receptor heterodimeric contexts

Thompson, P. D., Remus, L. S., Hsieh, J. C., Jurutka, P. W., Whitfield, G. K., Galligan, M. A., Encinas Dominguez, C., Haussler, C. A. & Haussler, M. R., Oct 25 2001, In : Journal of Molecular Endocrinology. 27, 2, p. 211-227 17 p.

Research output: Contribution to journalArticle

54 Scopus citations

Molecular Nature of the Vitamin D Receptor and its Role in Regulation of Gene Expression

Jurutka, P. W., Whitfield, G. K., Hsieh, J. C., Thompson, P. D., Haussler, C. A. & Haussler, M. R., Dec 1 2001, In : Reviews in Endocrine and Metabolic Disorders. 2, 2, p. 203-216 14 p.

Research output: Contribution to journalArticle

208 Scopus citations
2000

Molecular modeling, affinity labeling, and site-directed mutagenesis define the key points of interaction between the ligand-binding domain of the vitamin D nuclear receptor and 1α,25-dihydroxyvitamin D3

Swamy, N., Xu, W., Paz, N., Hsieh, J. C., Haussler, M. R., Maalouf, G. J., Mohr, S. C. & Ray, R., Oct 10 2000, In : Biochemistry. 39, 40, p. 12162-12171 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB

Jurutka, P. W., Remus, L. S., Whitfield, G. K., Thompson, P. D., Hsieh, J. C., Zitzer, H., Tavakkoli, P., Galligan, M. A., Dang, H. T. L., Haussler, C. A. & Haussler, M. R., Jan 1 2000, In : Molecular Endocrinology. 14, 3, p. 401-420 20 p.

Research output: Contribution to journalArticle

Open Access
297 Scopus citations
1999

Characterization of unique DNA-binding and transcriptional-activation functions in the carboxyl-terminal extension of the zinc finger region in the human vitamin D receptor

Hsieh, J. C., Whitfield, G. K., Oza, A. K., Dang, H. T. L., Price, J. N., Galligan, M. A., Jurutka, P. W., Thompson, P. D., Haussler, C. A. & Haussler, M. R., Dec 7 1999, In : Biochemistry. 38, 49, p. 16347-16358 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Vitamin D receptor displays DNA binding and transactivation as a heterodimer with the retinoid X receptor, but not with the thyroid hormone receptor

Thompson, P. D., Hsieh, J. C., Whitfield, G. K., Haussler, C. A., Jurutka, P. W., Galligan, M. A., Tillman, J. B., Spindler, S. R. & Haussler, M. R., Dec 1 1999, In : Journal of Cellular Biochemistry. 75, 3, p. 462-480 19 p.

Research output: Contribution to journalArticle

22 Scopus citations
1998

Novel nuclear localization signal between the two DNA-binding zinc fingers in the human vitamin D receptor

Hsieh, J. C., Shimizu, Y., Minoshima, S., Shimizu, N., Haussler, C. A., Jurutka, P. W. & Haussler, M. R., Jul 1 1998, In : Journal of Cellular Biochemistry. 70, 1, p. 94-109 16 p.

Research output: Contribution to journalArticle

56 Scopus citations

Suppression of ANP gene transcription by liganded vitamin D receptor: Involvement of specific receptor domains

Chen, S., Wu, J., Hsieh, J. C., Whitfield, G. K., Jurutka, P. W., Haussler, M. R. & Gardner, D. G., Jun 1998, In : Hypertension. 31, 6, p. 1338-1342 5 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations
1997
74 Scopus citations

The vitamin D hormone and its nuclear receptor: Molecular actions and disease states

Haussler, M. R., Haussler, C. A., Jurutka, P. W., Thompson, P. D., Hsieh, J. C., Remus, L. S., Selznick, S. H. & Whitfield, G. K., Sep 1 1997, In : Journal of Endocrinology. 154, SUPPL., p. S57-S73

Research output: Contribution to journalArticle

252 Scopus citations
1996

Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor

Nakajima, S., Hsieh, J. C., Jurutka, P. W., Galligan, M. A., Haussler, C. A., Whitfield, G. K. & Haussler, M. R., Mar 1 1996, In : Journal of Biological Chemistry. 271, 9, p. 5143-5149 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
76 Scopus citations

Vitamin D receptors from patients with resistance to 1,25- dihydroxyvitamin D3: Point mutations confer reduced transactivation in response to ligand and impaired interaction with the retinoid X receptor heterodimeric partner

Whitfield, G. K., Selznick, S. H., Haussler, C. A., Hsieh, J. C., Galligan, M. A., Jurutka, P. W., Thompson, P. D., Lee, S. M., Zerwekh, J. E. & Haussler, M. R., Dec 17 1996, In : Molecular Endocrinology. 10, 12, p. 1617-1631 15 p.

Research output: Contribution to journalArticle

107 Scopus citations
1995

A highly conserved region in the hormone-binding domain of the human vitamin D receptor contains residues vital for heterodimerization with retinoid X receptor and for transcriptional activation

Whitfield, G. K., Hsieh, J. C., Nakajima, S., MacDonald, P. N., Thompson, P. D., Jurutka, P. W., Haussler, C. A. & Haussler, M. R., Sep 1 1995, In : Molecular Endocrinology. 9, 9, p. 1166-1179 14 p.

Research output: Contribution to journalArticle

Open Access
84 Scopus citations

Genomic actions of 1,25-dihydroxyvitamin D3

Whitfield, G. K., Hsieh, J. C., Jurutka, P. W., Selznick, S. H., Haussler, C. A., MacDonald, P. N. & Haussler, M. R., Jan 1 1995, In : Journal of Nutrition. 125, 6 SUPPL., p. 1690S-1694S

Research output: Contribution to journalArticle

64 Scopus citations

New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone

Haussler, M. R., Jurutka, P. W., Hsieh, J. C., Thompson, P. D., Selznick, S. H., Haussler, C. A. & Whitfield, G. K., Aug 1995, In : Bone. 17, 2 SUPPL. 1, p. S33-S38

Research output: Contribution to journalArticle

96 Scopus citations

Receptor mediated genomic action of the 1,25(OH)2D3 hormone: Expression of the human vitamin D receptor in E. coli

Hsieh, J. C., Nakajima, S., Galligan, M. A., Jurutka, P. W., Haussler, C. A., Whitfield, G. K. & Haussler, M. R., Jun 1995, In : Journal of Steroid Biochemistry and Molecular Biology. 53, 1-6, p. 583-594 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

The T-Box near the Zinc Fingers of the Human Vitamin D Receptor Is Required for Heterodimeric DNA Binding and Transactivation

Hsieh, J. C., Jurutka, P. W., Selznick, S. H., Reeder, M. C., Haussler, C. A., Whitfield, G. K. & Haussler, M. R., Oct 4 1995, In : Biochemical and Biophysical Research Communications. 215, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

28 Scopus citations
1994
Open Access
95 Scopus citations
1993
85 Scopus citations
31 Scopus citations

Phosphorylation of the human vitamin D receptor by protein kinase C. Biochemical and functional evaluation of the serine 51 recognition site

Hsieh, J. C., Jurutka, P. W., Nakajima, S., Galligan, M. A., Haussler, C. A., Shimizu, Y., Shimizu, N., Whitfield, G. K. & Haussler, M. R., Jan 1 1993, In : Journal of Biological Chemistry. 268, 20, p. 15118-15126 9 p.

Research output: Contribution to journalArticle

101 Scopus citations
19 Scopus citations
1991

Human vitamin D receptor is selectively phosphorylated by protein kinase C on serine 51, a residue crucial to its trans-activation function

Hsieh, J. C., Jurutka, P. W., Galligan, M. A., Terpening, C. M., Haussler, C. A., Samuels, D. S., Shimizu, Y., Shimizu, N. & Haussler, M. R., Oct 15 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 20, p. 9315-9319 5 p.

Research output: Contribution to journalArticle

Open Access
181 Scopus citations

Mapping of the DNA linking tyrosine residue of the PRD1 terminal protein

Shiue, S. Y., Hsieh, J. C. & Ito, J., Jul 25 1991, In : Nucleic acids research. 19, 14, p. 3805-3810 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
1990

An essential arginine residue for initiation of protein-primed DNA replication

Hsieh, J. C., Yoo, S. K. U. & Ito, J., Jan 1 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 21, p. 8665-8669 5 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
1988

Possible evolutionary relationship between poliovirus RNA-linked protein VPg and PRD1 DNA-terminal protein

Hsieh, J. C. & Ito, J., May 11 1988, In : Nucleic acids research. 16, 9, 1 p.

Research output: Contribution to journalArticle

1987

Bacteriophage PRD1 DNA polymerase: evolution of DNA polymerases.

Jung, G. H., Leavitt, M. C., Hsieh, J. C. & Ito, J., Dec 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 23, p. 8287-8291 5 p.

Research output: Contribution to journalArticle

Open Access
60 Scopus citations

Primary structure of the DNA terminal protein of bacteriophage PRD1

Hsieh, J. C., Jung, G., Leavitt, M. C. & Ito, J., Nov 11 1987, In : Nucleic acids research. 15, 21, p. 8999-9009 11 p.

Research output: Contribution to journalArticle

15 Scopus citations