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Karen Taraszka Hastings

  • 303 Citations
  • 11 h-Index
1991 …2019
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  • 1 Similar Profiles
Sulfhydryl Compounds Medicine & Life Sciences
Oxidoreductases Medicine & Life Sciences
Interferon-gamma Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Melanoma Medicine & Life Sciences
Antigen Presentation Medicine & Life Sciences
Histocompatibility Antigens Class II Medicine & Life Sciences
Melanoma-Specific Antigens Medicine & Life Sciences

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Projects 2007 2016

GILT and regulation of Treg development in cutaneous autoimmunity

Hastings, K. T.

National Institutes of Health

9/10/13 → 8/31/16

Project: Research project

Regulatory T-Lymphocytes
Autoimmunity
Sulfhydryl Compounds
Interferon-gamma
Oxidoreductases

MHC Class II Antigen Processing and Immune Recognition of Melanoma

Hastings, K. T.

National Institutes of Health

9/1/07 → 8/31/13

Project: Research project

Histocompatibility Antigens Class II
Antigen Presentation
Sulfhydryl Compounds
Interferon-gamma
Melanoma

Research Output 1991 2019

  • 303 Citations
  • 11 h-Index
  • 15 Article
  • 2 Chapter

High GILT expression and an active and intact MHC class II antigen presentation pathway are associated with improved survival in melanoma

Buetow, K. H., Meador, L. R., Menon, H., Lu, Y. K., Brill, J., Cui, H., Roe, D. J., DiCaudo, D. J. & Hastings, K. T., Nov 15 2019, In : Journal of Immunology. 203, 10, p. 2577-2587 11 p.

Research output: Contribution to journal › Article

Histocompatibility Antigens Class II
Antigen Presentation
Melanoma
Survival
Melanocytes
1 Citation (Scopus)

Nab2 maintains thymus cellularity with aging and stress

Hastings, K. T., Elizalde, D., Muppana, L., Levine, S., Kamel, C. M., Ingram, W. M., Kirkpatrick, J. T., Hu, C., Rausch, M. P. & Gallitano-Mendel, A. L., May 1 2017, In : Molecular Immunology. 85, p. 185-195 11 p.

Research output: Contribution to journal › Article

Thymus Gland
Thymocytes
T-Lymphocytes
Immediate-Early Genes
Biological Factors
5 Citations (Scopus)

Gamma-interferon-inducible lysosomal thiol reductase is upregulated in human melanoma

Nguyen, J., Bernert, R., In, K., Kang, P., Sebastiao, N., Hu, C. & Hastings, K. T., Mar 23 2016, In : Melanoma Research. 26, 2, p. 125-137 13 p.

Research output: Contribution to journal › Article

Sulfhydryl Compounds
Interferon-gamma
Melanoma
Oxidoreductases
Nevus
2 Citations (Scopus)

An exhaustion-like phenotype constrains the activity of CD4+ T cells specific for a self and melanoma antigen

Rausch, M. P. & Hastings, K. T., Apr 15 2015, In : PLoS One. 10, 4, e0123332.

Research output: Contribution to journal › Article

Melanoma-Specific Antigens
T-cells
Autoantigens
melanoma
T-lymphocytes
14 Citations (Scopus)

Diverse cellular and organismal functions of the lysosomal thiol reductase GILT

Rausch, M. P. & Hastings, K. T., Apr 16 2015, In : Molecular Immunology. 68, p. 124-128 5 p.

Research output: Contribution to journal › Article

Sulfhydryl Compounds
Interferon-gamma
Oxidoreductases
Cross-Priming
Epitopes