• 8004 Citations
  • 45 h-Index
19972019

Research output per year

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Research Output

2019

Coordination of non-innocent nitrogen oxide ligands: terminology

Miranda, K. M., May 1 2019, In : Journal of Biological Inorganic Chemistry. 24, 3, p. 315-316 2 p.

Research output: Contribution to journalComment/debate

Design and synthesis of rosiglitazone-ferulic acid-nitric oxide donor trihybrids for improving glucose tolerance

Liu, J., Huang, Z., Ma, W., Peng, S., Li, Y., Miranda, K. M., Tian, J. & Zhang, Y., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 650-665 16 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

The nitroxyl donor Angeli's salt ameliorates Staphylococcus aureus-induced septic arthritis in mice

Staurengo-Ferrari, L., Ruiz-Miyazawa, K. W., Pinho-Ribeiro, F. A., Domiciano, T. P., Fattori, V., Mizokami, S. S., Pelayo, J. S., Bordignon, J., Figueiredo, F., Casagrande, R., Miranda, K. M. & Verri, W. A., Jul 1 2017, In : Free Radical Biology and Medicine. 108, p. 487-499 13 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

A celebration of inorganic lives: Interview with Peter C. Ford (UC Santa Barbara)

Miranda, K. M., Jan 1 2016, In : Coordination Chemistry Reviews. 306, p. 724-733 10 p.

Research output: Contribution to journalArticle

HNO Donors: Angeli's Salt and Related Diazeniumdiolates

Basudhar, D., Bharadwaj, G., Salmon, D. J. & Miranda, K. M., Sep 1 2016, The Chemistry and Biology of Nitroxyl (HNO). Elsevier Inc., p. 11-36 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Special issue in honour of Prof. Peter C. Ford

Miranda, K. M., Jan 1 2016, In : Coordination Chemistry Reviews. 306, p. 445-446 2 p.

Research output: Contribution to journalArticle

The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain

Longhi-Balbinot, D. T., Rossaneis, A. C., Pinho-Ribeiro, F. A., Bertozzi, M. M., Cunha, F. Q., Alves-Filho, J. C., Cunha, T. M., Peron, J. P. S., Miranda, K. M., Casagrande, R. & Verri, W. A., Aug 25 2016, In : Chemico-Biological Interactions. 256, p. 1-8 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Chemotherapeutic potential of diazeniumdiolate-based aspirin prodrugs in breast cancer

Basudhar, D., Cheng, R. C., Bharadwaj, G., Ridnour, L. A., Wink, D. A. & Miranda, K. M., Jun 1 2015, In : Free Radical Biology and Medicine. 83, p. 101-114 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Comparison of the chemical reactivity of synthetic peroxynitrite with that of the autoxidation products of nitroxyl or its anion

Jorolan, J. H., Buttitta, L. A., Cheah, C. & Miranda, K. M., Apr 2 2015, In : Nitric Oxide - Biology and Chemistry. 44, p. 39-46 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Signaling and stress: The redox landscape in NOS2 biology

Thomas, D. D., Heinecke, J. L., Ridnour, L. A., Cheng, R. Y., Kesarwala, A. H., Switzer, C. H., McVicar, D. W., Roberts, D. D., Glynn, S., Fukuto, J. M., Wink, D. A. & Miranda, K. M., Jun 2 2015, In : Free Radical Biology and Medicine. 87, p. 204-225 22 p., 12462.

Research output: Contribution to journalReview article

54 Scopus citations
2014

Analysis of the HNO and NO donating properties of alicyclic amine diazeniumdiolates

Bharadwaj, G., Benini, P. G. Z., Basudhar, D., Ramos-Colon, C. N., Johnson, G. M., Larriva, M. M., Keefer, L. K., Andrei, D. & Miranda, K. M., Nov 15 2014, In : Nitric Oxide - Biology and Chemistry. 42, p. 70-78 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Corrigendum to 'quantitative detection of nitroxyl upon trapping with glutathione and labeling with a specific fluorogenic reagent' [Free radical biology and medicine 63(2013) 476-484]

Johnson, G. M., Chozinski, T. J., Salmon, D. J., Moghaddam, A. D., Chen, H. C. & Miranda, K. M., Dec 2014, In : Free Radical Biology and Medicine. 77, 1 p.

Research output: Contribution to journalComment/debate

Gene expression profiles of NO- and HNO-donor treated breast cancer cells: Insights into tumor response and resistance pathways

Cheng, R. Y. S., Basudhar, D., Ridnour, L. A., Heinecke, J. L., Kesarwala, A. H., Glynn, S., Switzer, C. H., Ambs, S., Miranda, K. M. & Wink, D. A., Dec 1 2014, In : Nitric Oxide - Biology and Chemistry. 43, p. 17-28 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Glutathione sulfinamide serves as a selective, endogenous biomarker for nitroxyl after exposure to therapeutic levels of donors

Johnson, G. M., Chozinski, T. J., Gallagher, E. S., Aspinwall, C. A. & Miranda, K. M., Nov 2014, In : Free Radical Biology and Medicine. 76, p. 299-307 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Light-triggered and cysteine-mediated nitric oxide release from a biodegradable starch-based film

Roveda, A. C., De Fazio Aguiar, H., Miranda, K. M., Tadini, C. C. & Franco, D. W., Nov 7 2014, In : Journal of Materials Chemistry B. 2, 41, p. 7232-7242 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Nitroxyl inhibits overt pain-like behavior in mice: Role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway

Staurengo-Ferrari, L., Zarpelon, A. C., Longhi-Balbinot, D. T., Marchesi, M., Cunha, T. M., Alves-Filho, J. C., Cunha, F. Q., Ferreira, S. H., Casagrande, R., Miranda, K. M. & Verri, W. A., Aug 2014, In : Pharmacological Reports. 66, 4, p. 691-698 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Persulfides and the cellular thiol landscape

Miranda, K. M. & Wink, D. A., May 27 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 21, p. 7505-7506 2 p.

Research output: Contribution to journalComment/debate

15 Scopus citations
2013

Biological nitric oxide signalling: Chemistry and terminology

Heinrich, T. A., Da Silva, R. S., Miranda, K. M., Switzer, C. H., Wink, D. A. & Fukuto, J. M., Aug 1 2013, In : British Journal of Pharmacology. 169, 7, p. 1417-1429 13 p.

Research output: Contribution to journalReview article

108 Scopus citations

Mechanisms of nitric oxide reactions mediated by biologically relevant metal centers

Ford, P. C., Pereira, J. C. M. & Miranda, K. M., Oct 5 2013, In : Structure and Bonding. 154, p. 99-136 38 p.

Research output: Contribution to journalReview article

6 Scopus citations

Synthesis and chemical and biological comparison of nitroxyl- and nitric oxide-releasing diazeniumdiolate-based aspirin derivatives

Basudhar, D., Bharadwaj, G., Cheng, R. Y., Jain, S., Shi, S., Heinecke, J. L., Holland, R. J., Ridnour, L. A., Caceres, V. M., Spadari-Bratfisch, R. C., Paolocci, N., Velázquez-Martínez, C. A., Wink, D. A. & Miranda, K. M., Oct 31 2013, In : Journal of Medicinal Chemistry. 56, 20, p. 7804-7820 17 p.

Research output: Contribution to journalArticle

48 Scopus citations

The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats

Zarpelon, A. C., Souza, G. R., Cunha, T. M., Schivo, I. R. S., Marchesi, M., Casagrande, R., Pinge-Filho, P., Cunha, F. Q., Ferreira, S. H., Miranda, K. M. & Verri, W. A., Aug 1 2013, In : Neuropharmacology. 71, p. 1-9 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

HNO and NO release from a primary amine-based diazeniumdiolate as a function of pH

Salmon, D. J., De Holding, C. L. T., Thomas, L., Peterson, K. V., Goodman, G. P., Saavedra, J. E., Srinivasan, A., Davies, K. M., Keefer, L. K. & Miranda, K. M., Apr 18 2011, In : Inorganic Chemistry. 50, 8, p. 3262-3270 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems

Flores-Santana, W., Salmon, D. J., Donzelli, S., Switzer, C. H., Basudhar, D., Ridnour, L., Cheng, R., Glynn, S. A., Paolocci, N., Fukuto, J. M., Miranda, K. M. & Wink, D. A., May 1 2011, In : Antioxidants and Redox Signaling. 14, 9, p. 1659-1674 16 p.

Research output: Contribution to journalReview article

68 Scopus citations
2010

Dual mechanisms of HNO generation by a nitroxyl prodrug of the diazeniumdiolate (NONOate) class

Andrei, D., Salmon, D. J., Donzelli, S., Wahab, A., Klose, J. R., Citro, M. L., Saavedra, J. E., Wink, D. A., Miranda, K. M. & Keefer, L. K., Nov 24 2010, In : Journal of the American Chemical Society. 132, 46, p. 16526-16532 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Reactions of HNO with heme proteins: New routes to HNO-heme complexes and insight into physiological effects

Kumars, M. R., Fukuto, J. M., Miranda, K. M. & Farmer, P. J., Jul 19 2010, In : Inorganic Chemistry. 49, 14, p. 6283-6292 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

The bell-shaped curve for peroxynitrite-mediated oxidation and nitration of NO/O2.- is alive and well

Jourd'heuil, D., Lancaster, J. R., Fukuto, J., Roberts, D. D., Miranda, K. M., Mayer, B., Grisham, M. B. & Wink, D. A., Aug 27 2010, In : Journal of Biological Chemistry. 285, 35, p. le15

Research output: Contribution to journalLetter

6 Scopus citations
2009

Comparing the chemical biology of NO and HNO

Flores-Santana, W., Switzer, C., Ridnour, L. A., Basudhar, D., Mancardi, D., Donzelli, S., Thomas, D. D., Miranda, K. M., Fukuto, J. M. & Wink, D. A., Aug 1 2009, In : Archives of Pharmacal Research. 32, 8, p. 1139-1153 15 p.

Research output: Contribution to journalReview article

29 Scopus citations

Kinetic feasibility of nitroxyl reduction by physiological reductants and biological implications

Jackson, M. I., Han, T. H., Serbulea, L., Dutton, A., Ford, E., Miranda, K. M., Houk, K. N., Wink, D. A. & Fukuto, J. M., Oct 15 2009, In : Free Radical Biology and Medicine. 47, 8, p. 1130-1139 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

The effects of nitroxyl (HNO) on soluble guanylate cyclase activity. Interactions at ferrous heme and cysteine thiols

Miller, T. W., Cherney, M. M., Lee, A. J., Francolean, N. E., Farmer, P. J., King, S. B., Hobbs, A. J., Miranda, K. M., Burstyn, J. N. & Fukuto, J. M., Aug 14 2009, In : Journal of Biological Chemistry. 284, 33, p. 21788-21796 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

The emergence of nitroxyl (HNO) as a pharmacological agent

Switzer, C. H., Flores-Santana, W., Mancardi, D., Donzelli, S., Basudhar, D., Ridnour, L. A., Miranda, K. M., Fukuto, J. M., Paolocci, N. & Wink, D. A., Jul 1 2009, In : Biochimica et Biophysica Acta - Bioenergetics. 1787, 7, p. 835-840 6 p.

Research output: Contribution to journalReview article

87 Scopus citations
2008

Bordetella bronchiseptica responses to physiological reactive nitrogen and oxygen stresses

Omsland, A., Miranda, K. M., Friedman, R. L. & Boitano, S., Jul 1 2008, In : FEMS Microbiology Letters. 284, 1, p. 92-101 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine

Donzelli, S., Espey, M. G., Flores-Santana, W., Switzer, C. H., Yeh, G. C., Huang, J., Stuehr, D. J., King, S. B., Miranda, K. M. & Wink, D. A., Sep 1 2008, In : Free Radical Biology and Medicine. 45, 5, p. 578-584 7 p.

Research output: Contribution to journalArticle

62 Scopus citations

Persistent susceptibility of cathepsin B to irreversible inhibition by nitroxyl (HNO) in the presence of endogenous nitric oxide

Väänänen, A. J., Salmenperä, P., Hukkanen, M., Miranda, K. M., Harjula, A., Rauhala, P. & Kankuri, E., Sep 15 2008, In : Free Radical Biology and Medicine. 45, 6, p. 749-755 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

The inducing NO-vasodilation by chemical reduction of coordinated nitrite ion in cis-[Ru(NO2)L(bpy)2]+ complex

Da Rocha, Z. N., Marchesi, M. S. P., Molin, J. C., Lunardi, C. N., Miranda, K. M., Bendhack, L. M., Ford, P. C. & Da Silva, R. S., Aug 15 2008, In : Dalton Transactions. 32, p. 4282-4287 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
2007

The pharmacology of nitroxyl (HNO) and its therapeutic potential: Not just the janus face of NO11This review is dedicated to the career of Prof. Herbert T. Nagasawa, a pioneer in the field of HNO chemistry, biochemistry and pharmacology.

Paolocci, N., Jackson, M. I., Lopez, B. E., Miranda, K., Tocchetti, C. G., Wink, D. A., Hobbs, A. J. & Fukuto, J. M., Feb 1 2007, In : Pharmacology and Therapeutics. 113, 2, p. 442-458 17 p.

Research output: Contribution to journalReview article

178 Scopus citations
2006

Discriminating formation of HNO from other reactive nitrogen oxide species

Donzelli, S., Espey, M. G., Thomas, D. D., Mancardi, D., Tocchetti, C. G., Ridnour, L. A., Paolocci, N., King, S. B., Miranda, K. M., Lazzarino, G., Fukuto, J. M. & Wink, D. A., Mar 15 2006, In : Free Radical Biology and Medicine. 40, 6, p. 1056-1066 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

Mechanism of pH-dependent decomposition of monoalkylamine diazeniumdiolates to form HNO and NO, deduced from the model compound methylamine diazeniumdiolate, density functional theory, and CBS-QB3 calculations

Dutton, A. S., Suhrada, C. P., Miranda, K. M., Wink, D. A., Fukuto, J. M. & Houk, K. N., Mar 20 2006, In : Inorganic Chemistry. 45, 6, p. 2448-2456 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Peroxynitrite and myocardial contractility: In vivo versus in vitro effects

Katori, T., Donzelli, S., Tocchetti, C. G., Miranda, K. M., Cormaci, G., Thomas, D. D., Ketner, E. A., Lee, M. J., Mancardi, D., Wink, D. A., Kass, D. A. & Paolocci, N., Nov 15 2006, In : Free Radical Biology and Medicine. 41, 10, p. 1606-1618 13 p.

Research output: Contribution to journalArticle

45 Scopus citations

The activation of metabolites of nitric oxide synthase by metals is both redox and oxygen dependent: A new feature of nitrogen oxide signaling

Donzelli, S., Switzer, C. H., Thomas, D. D., Ridnour, L. A., Espey, M. G., Isenberg, J. S., Tocchetti, C. G., King, S. B., Lazzarino, G., Miranda, K. M., Roberts, D. D., Feelisch, M. & Wink, D. A., Jul 1 2006, In : Antioxidants and Redox Signaling. 8, 7-8, p. 1363-1371 9 p.

Research output: Contribution to journalReview article

23 Scopus citations
2005

Comparison of the chemical biology of NO and HNO: An inorganic perspective

Miranda, K. M., Ridnour, L., Esprey, M., Citrin, D., Thomas, D., Mancardi, D., Donzelli, S., Wink, D. A., Katori, T., Tocchetti, C. G., Ferlito, M., Paolocci, N. & Fukuto, J. M., Jan 1 2005, In : Progress in Inorganic Chemistry. 54, p. 349-384 36 p.

Research output: Contribution to journalReview article

10 Scopus citations

Comparison of the NO and HNO donating properties of diazeniumdiolates: Primary amine adducts release HNO in vivo

Miranda, K. M., Katori, T., Torres De Holding, C. L., Thomas, L., Ridnour, L. A., McLendon, W. J., Cologna, S. M., Dutton, A. S., Champion, H. C., Mancardi, D., Tocchetti, C. G., Saavedra, J. E., Keefer, L. K., Houk, K. N., Fukuto, J. M., Kass, D. A., Paolocci, N. & Wink, D. A., Dec 29 2005, In : Journal of Medicinal Chemistry. 48, 26, p. 8220-8228 9 p.

Research output: Contribution to journalArticle

96 Scopus citations

Donors of HNO

Miranda, K. M., Nagasawa, H. T. & Toscano, J. P., Aug 31 2005, In : Current topics in medicinal chemistry. 5, 7, p. 649-664 16 p.

Research output: Contribution to journalReview article

67 Scopus citations

Mechanism of aerobic decomposition of Angeli's salt (Sodium Trioxodinitrate) at physiological pH

Miranda, K. M., Dutton, A. S., Ridnour, L. A., Foreman, C. A., Ford, E., Paolocci, N., Katori, T., Tocchetti, C. G., Mancardi, D., Thomas, D. D., Espey, M. G., Houk, K. N., Fukuto, J. M. & Wink, D. A., Jan 19 2005, In : Journal of the American Chemical Society. 127, 2, p. 722-731 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Nitroxyl (HNO): Chemistry, biochemistry, and pharmacology

Fukuto, J. M., Switzer, C. H., Miranda, K. M. & Wink, D. A., Mar 2 2005, In : Annual Review of Pharmacology and Toxicology. 45, p. 335-355 21 p.

Research output: Contribution to journalReview article

98 Scopus citations

The chemistry of nitroxyl (HNO) and implications in biology

Miranda, K. M., Feb 1 2005, In : Coordination Chemistry Reviews. 249, 3-4 SPEC. ISS., p. 433-455 23 p.

Research output: Contribution to journalReview article

235 Scopus citations
2004

Antioxidant properties of nitric oxide in cellular physiological and pathophysiological mechanisms. The implications of biological balance between NO and oxidative stress

Ridnour, L. A., Thomas, D. D., Mancardi, D., Donzelli, S., Paolocci, N., Pagliaro, P., Miranda, K. M., Krishna, M., Fukuto, J., Grisham, M. B., Mitchell, J. B., Espey, M. G. & Wink, D. A., Sep 1 2004, In : Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents. 3, 3, p. 181-188 8 p.

Research output: Contribution to journalReview article

8 Scopus citations

The chemical dynamics of NO and reactive nitrogen oxides: A practical guide

Mancardi, D., Ridnour, L. A., Thomas, D. D., Katori, T., Tocchetti, C. G., Espey, M. G., Miranda, K. M., Paolocci, N. & Wink, D. A., Nov 1 2004, In : Current Molecular Medicine. 4, 7, p. 723-740 18 p.

Research output: Contribution to journalReview article

34 Scopus citations

The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations

Ridnour, L. A., Thomas, D. D., Mancardi, D., Espey, M. G., Miranda, K. M., Paolocci, N., Feelisch, M., Fukuto, J. & Wink, D. A., Jan 1 2004, In : Biological Chemistry. 385, 1, p. 1-10 10 p.

Research output: Contribution to journalReview article

195 Scopus citations
2003

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system

Miranda, K. M., Paolocci, N., Katori, T., Thomas, D. D., Ford, E., Bartberger, M. D., Espey, M. G., Kass, D. A., Feelisch, M., Fukuto, J. M. & Wink, D. A., Aug 5 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 16, p. 9196-9201 6 p.

Research output: Contribution to journalArticle

219 Scopus citations

Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins: A chemical discussion of the differential biological effects of these redox related products of NOS

Miranda, K. M., Nims, R. W., Thomas, D. D., Espey, M. G., Citrin, D., Bartberger, M. D., Paolocci, N., Fukuto, J. M., Feelisch, M. & Wink, D. A., Jan 1 2003, In : Journal of Inorganic Biochemistry. 93, 1-2, p. 52-60 9 p.

Research output: Contribution to journalArticle

105 Scopus citations