Keith A Joiner

  • 10110 Citations
  • 55 h-Index
1969 …2018

Research output per year

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Research Output

  • 10110 Citations
  • 55 h-Index
  • 220 Article
  • 2 Chapter
  • 1 Conference contribution
  • 1 Paper
1996

Structure and function of the Toxoplasma gondii vacuole

Joiner, K. A., Bermudes, D., Sinai, A., Qi, H., Polotsky, V. & Beckers, C. J. M., 1996, In : Annals of the New York Academy of Sciences. 797, p. 1-7 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
1995

Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii: Implications for the target of macrolide antibiotics

Beckers, C. J. M., Roos, D. S., Donald, R. G. K., Luft, B. J., Schwab, J. C., Cao, Y. & Joiner, K. A., Jan 1995, In : Journal of Clinical Investigation. 95, 1, p. 367-376 10 p.

Research output: Contribution to journalArticle

98 Scopus citations

Toxoplasma gondii tachyzoites possess an unusual plasma membrane adenosine transporter

Conrad Schwab, J., Afifi Afifi, M., Pizzorno, G., Handschumacher, R. E. & Joiner, K. A., 1995, In : Molecular and Biochemical Parasitology. 70, 1-2, p. 59-69 11 p.

Research output: Contribution to journalArticle

44 Scopus citations
1994
67 Scopus citations

Cloning of a cDNA encoding the dense granule protein GRA3 from Toxoplasma gondii

Bermudes, D., Dubremetz, J. F., Achbarou, A. & Joiner, K. A., 1994, In : Molecular and Biochemical Parasitology. 68, 2, p. 247-257 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Dictyostelium discoideum mutants with conditional defects in phagocytosis

Cohen, C. J., Bacon, R., Clarke, M., Joiner, K. A. & Mellman, I., Aug 1994, In : Journal of Cell Biology. 126, 4, p. 955-966 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Isolation, cDNA sequences, and biochemical characterization of the major cyclosporin-binding proteins of Toxoplasma gondii

High, K. P., Joiner, K. A. & Handschumacher, R. E., Mar 25 1994, In : Journal of Biological Chemistry. 269, 12, p. 9105-9112 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Localization of azithromycin in Toxoplasma gondii-infected cells

Schwab, J. C., Cao, Y., Slowik, M. R. & Joiner, K. A., 1994, In : Antimicrobial Agents and Chemotherapy. 38, 7, p. 1620-1627 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Structure and function of the parasitophorous vacuole membrane surrounding Toxoplasma gondii

Joiner, K. A., Beckers, C. J. M., Bermudes, D., Ossorio, P. N., Schwab, J. C. & Dubremetz, J. F., 1994, In : Annals of the New York Academy of Sciences. 730, p. 1-6 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Tandemly repeated genes encode nucleoside triphosphate hydrolase isoforms secreted into the parasitophorous vacuole of Toxoplasma gondii

Bermudes, D., Peck, K. R., Afifi, M. A., Beckers, C. J. M. & Joiner, K. A., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 29252-29260 9 p.

Research output: Contribution to journalArticle

136 Scopus citations
276 Scopus citations

The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm

Beckers, C. J. M., Dubremetz, J. F., Mercereau-Puijalon, O. & Joiner, K. A., Nov 1994, In : Journal of Cell Biology. 127, 4, p. 947-961 15 p.

Research output: Contribution to journalArticle

193 Scopus citations

The type I macrophage scavenger receptor binds to Gram-positive bacteria and recognizes lipoteichoic acid

Dunne, D. W., Resnick, D., Greenberg, J., Krieger, M. & Joiner, K. A., Mar 1 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 5, p. 1863-1867 5 p.

Research output: Contribution to journalArticle

281 Scopus citations
1993

A partial cDNA clone of trypomastigote decay-accelerating factor (T-DAF), a developmentally regulated complement inhibitor of Trypanosoma cruzi, has genetic and functional similarities to the human complement inhibitor DAF

Tambourgi, D. V., Kipnis, T. L., Da Silva, W. D., Joiner, K. A., Sher, A., Heath, S., Hall, B. F. & Ogden, G. B., 1993, In : Infection and Immunity. 61, 9, p. 3656-3663 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Cell entry by Toxoplasma gondii: all paths do not lead to success

Joiner, K. A., 1993, In : Research in Immunology. 144, 1, p. 34-38 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
25 Scopus citations

Kinetics and pattern of organelle exocytosis during Toxoplasma gondii/host-cell interaction

Dubremetz, J. F., Achbarou, A., Bermudes, D. & Joiner, K. A., May 1993, In : Parasitology Research. 79, 5, p. 402-408 7 p.

Research output: Contribution to journalArticle

151 Scopus citations

Potassium cyanide protects escherichia coli from complement killing by the inhibition of c3 convertase activity

Bloch, E. F., Rahbar, M., Wright, A. K., Patterson, A. M., Souza, R. F., Hammer, C. H., Gaither, T. A. & Joiner, K. A., 1993, In : Immunological Investigations. 22, 2, p. 127-149 23 p.

Research output: Contribution to journalArticle

4 Scopus citations

The role of parasites in generating evolutionary novelty

Bermudes, D. & Joiner, K. A., 1993, In : Parasitology Today. 9, 12, p. 458-463 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Toxoplasma gondii: A protozoan for the nineties

Joiner, K. A. & Dubremetz, J. F., 1993, In : Infection and Immunity. 61, 4, p. 1169-1172 4 p.

Research output: Contribution to journalArticle

104 Scopus citations
9 Scopus citations
1992

Desialylation of lysosomal membrane glycoproteins by Trypanosoma cruzi: A role for the surface neuraminidase in facilitating parasite entry into the host cell cytoplasm

Hall, B. F., Webster, P., Ma, A. K., Joiner, K. A. & Andrews, N. W., Aug 1 1992, In : Journal of Experimental Medicine. 176, 2, p. 313-325 13 p.

Research output: Contribution to journalArticle

116 Scopus citations

Laminin enhances binding of Toxoplasma gondii tachyzoites to J774 murine macrophage cells

Furtado, G. C., Slowik, M., Kleinman, H. K. & Joiner, K. A., 1992, In : Infection and Immunity. 60, 6, p. 2337-2342 6 p.

Research output: Contribution to journalArticle

66 Scopus citations
69 Scopus citations
1991

Cell attachment and entry by Toxoplasma gondii

Joiner, K. A., 1991, Behring Institut Mitteilungen. 88 ed. p. 20-26 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations
31 Scopus citations

Rhoptry lipids and parasitophorous vacuole formation: A slippery issue

Joiner, K. A., 1991, In : Parasitology Today. 7, 9, p. 226-227 2 p.

Research output: Contribution to journalArticle

26 Scopus citations

Strategies of obligate intracellular parasites for evading host defences

Hall, B. F. & Joiner, K. A., 1991, In : Immunology Today. 12, 3

Research output: Contribution to journalArticle

43 Scopus citations

Strategies of obligate intracellular parasites for evading host defences

Hall, B. F. & Joiner, K. A., 1991, In : Parasitology Today. 7, 3, p. 22-27 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Why do so many surface proteins of trypanosomatids have GPI-anchors?

Webster, P., Joiner, K. A. & Andrews, N. W., 1991, In : Cell Biology International Reports. 15, 9 PART 1, p. 799-813 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
1990

Serum resistance of metacyclic stage Leishmania major promastigotes is due to release of C5b-9

Puentes, S. M., Da Silva, R. P., Sacks, D. L., Hammer, C. H. & Joiner, K. A., Dec 15 1990, In : Journal of Immunology. 145, 12, p. 4311-4316 6 p.

Research output: Contribution to journalArticle

105 Scopus citations

Toxoplasma gondii: Fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts

Joiner, K. A., Fuhrman, S. A., Miettinen, H. M., Kasper, L. H. & Mellman, I., Aug 10 1990, In : Science. 249, 4969, p. 641-646 6 p.

Research output: Contribution to journalArticle

360 Scopus citations
1989

Binding and release of C3 from Leishmania donovani promastigotes during incubation in normal human serum

Puentes, S. M., Dwyer, D. M., Bates, P. A. & Joiner, K. A., 1989, In : Journal of Immunology. 143, 11, p. 3743-3749 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Complement activation and C3 binding by serum-sensitive and serum-resistant strains of Pseudomonas aeruginosa

Schiller, N. L., Hatch, R. A. & Joiner, K. A., 1989, In : Infection and Immunity. 57, 6, p. 1707-1713 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Complement binding on serum-sensitive and serumresistant transformants of Neisseria gonorrhoeae: effect of presensitization with a non-bactericidal monoclonal antibody

Joiner, K. A., Puentes, S. M., Warren, K. A., Scales, R. A. & Judd, R. C., 1989, In : Microbial Pathogenesis. 6, 5, p. 343-350 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Complement component C1q enhances invasion of human mononuclear phagocytes and fibroblasts by Trypanosoma cruzi trypomastigotes

Rimoldi, M. T., Tenner, A. J., Bobak, D. A. & Joiner, K. A., 1989, In : Journal of Clinical Investigation. 84, 6, p. 1982-1989 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Complement evasion by protozoa

Fuhrman, S. A. & Joiner, K. A., 1989, In : Experimental Parasitology. 68, 4, p. 474-481 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages

Da Silva, R. P., Hall, B. F., Joiner, K. A. & Sacks, D. L., 1989, In : Journal of Immunology. 143, 2, p. 617-622 6 p.

Research output: Contribution to journalArticle

186 Scopus citations

Halogenation and proteolysis of complement component C3 on Salmonella typhimurium during phagocytosis by human neutrophils

Joiner, K. A. & Schweinle, J. E., 1989, In : Journal of Immunology. 142, 9, p. 3164-3170 7 p.

Research output: Contribution to journalArticle

Human mannose-binding protein activates the alternative complement pathway and enhances serum bactericidal activity on a mannose-rich isolate of Salmonella

Schweinle, J. E., Ezekowitz, R. A. B., Tenner, A. J., Kuhlman, M. & Joiner, K. A., 1989, In : Journal of Clinical Investigation. 84, 6, p. 1821-1829 9 p.

Research output: Contribution to journalArticle

113 Scopus citations

Interaction of Neisseria gonorrhoeae with classical complement components, C1-inhibitor, and a monoclonal antibody directed against the Neisserial H.8 antigen

Schweinle, J. E., Hitchcock, P. J., Tenner, A. J., Hammer, C. H., Frank, M. M. & Joiner, K. A., 1989, In : Journal of Clinical Investigation. 83, 2, p. 397-403 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Lytic rabbit IgG for tissue culture trypomastigotes of Trypanosoma cruzi alters the extent and form of complement deposition

Rimoldi, M. T., Tartanian, A. & Joiner, K. A., 1989, In : Experimental Parasitology. 68, 2, p. 160-167 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Multimeric C9 within C5b-9 deposits in unique locations in the cell wall of Salmonella typhimurium

Joiner, K. A., Tartanian, A. B., Hammer, C. H. & Schweinle, J. E., 1989, In : Journal of Immunology. 142, 12, p. 4450-4457 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Purification, toxicity, and antiendotoxin activity of polymyxin B nonapeptide

Danner, R. L., Joiner, K. A., Rubin, M., Patterson, W. H., Johnson, N., Ayers, K. M. & Parillo, J. E., 1989, In : Antimicrobial Agents and Chemotherapy. 33, 9, p. 1428-1434 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

The human mannose-binding protein functions as an opsonin

Kuhlman, M., Joiner, K. A. & Ezekowitz, R. A. B., 1989, In : Journal of Experimental Medicine. 169, 5, p. 1733-1745 13 p.

Research output: Contribution to journalArticle

367 Scopus citations

The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes

Joiner, K. A., Ganz, T., Albert, J. & Rotrosen, D., 1989, In : Journal of Cell Biology. 109, 6 I, p. 2771-2782 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

Toxoplasma gondii: Mechanism of resistance to complement-mediated killing

Fuhrman, S. A. & Joiner, K. A., 1989, In : Journal of Immunology. 142, 3, p. 940-947 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
1988

Biochemical characterization of a factor produced by trypomastigotes of Trypanosoma cruzi that accelerates the decay of complement C3 convertases

Joiner, K. A., DaSilva, W. D., Rimoldi, M. T., Hammer, C. H., Sher, A. & Kipnis, T. L., 1988, In : Journal of Biological Chemistry. 263, 23, p. 11327-11335 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Complement binding by two developmental stages of Leishmania major promastigotes varying in expression of a surface lipophosphoglycan

Puentes, S. M., Sacks, D. L., Da Silva, R. P. & Joiner, K. A., 1988, In : Journal of Experimental Medicine. 167, 3, p. 887-902 16 p.

Research output: Contribution to journalArticle

146 Scopus citations