Keith A Joiner

  • 10267 Citations
  • 55 h-Index
1969 …2020

Research output per year

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Research Output

1992
70 Scopus citations
1993

A partial cDNA clone of trypomastigote decay-accelerating factor (T-DAF), a developmentally regulated complement inhibitor of Trypanosoma cruzi, has genetic and functional similarities to the human complement inhibitor DAF

Tambourgi, D. V., Kipnis, T. L., Da Silva, W. D., Joiner, K. A., Sher, A., Heath, S., Hall, B. F. & Ogden, G. B., Jan 1 1993, In : Infection and Immunity. 61, 9, p. 3656-3663 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Cell entry by Toxoplasma gondii: all paths do not lead to success

Joiner, K. A., 1993, In : Research in Immunology. 144, 1, p. 34-38 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
25 Scopus citations

Kinetics and pattern of organelle exocytosis during Toxoplasma gondii/host-cell interaction

Dubremetz, J. F., Achbarou, A., Bermudes, D. & Joiner, K. A., May 1 1993, In : Parasitology Research. 79, 5, p. 402-408 7 p.

Research output: Contribution to journalArticle

155 Scopus citations

Potassium cyanide protects escherichia coli from complement killing by the inhibition of c3 convertase activity

Bloch, E. F., Rahbar, M., Wright, A. K., Patterson, A. M., Souza, R. F., Hammer, C. H., Gaither, T. A. & Joiner, K. A., Jan 1 1993, In : Immunological Investigations. 22, 2, p. 127-149 23 p.

Research output: Contribution to journalArticle

4 Scopus citations

The role of parasites in generating evolutionary novelty

Bermudes, D. & Joiner, K. A., Dec 1993, In : Parasitology Today. 9, 12, p. 458-463 6 p.

Research output: Contribution to journalReview article

6 Scopus citations

Toxoplasma gondii: A protozoan for the nineties

Joiner, K. A. & Dubremetz, J. F., Apr 8 1993, In : Infection and Immunity. 61, 4, p. 1169-1172 4 p.

Research output: Contribution to journalShort survey

105 Scopus citations
9 Scopus citations
1994
68 Scopus citations

Cloning of a cDNA encoding the dense granule protein GRA3 from Toxoplasma gondii

Bermudes, D., Dubremetz, J. F., Achbarou, A. & Joiner, K. A., Dec 1994, In : Molecular and Biochemical Parasitology. 68, 2, p. 247-257 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Dictyostelium discoideum mutants with conditional defects in phagocytosis

Cohen, C. J., Bacon, R., Clarke, M., Joiner, K. & Mellman, I., Aug 1 1994, In : Journal of Cell Biology. 126, 4, p. 955-966 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Isolation, cDNA sequences, and biochemical characterization of the major cyclosporin-binding proteins of Toxoplasma gondii

High, K. P., Joiner, K. A. & Handschumacher, R. E., Mar 25 1994, In : Journal of Biological Chemistry. 269, 12, p. 9105-9112 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Localization of azithromycin in Toxoplasma gondii-infected cells

Schwab, J. C., Cao, Y., Slowik, M. R. & Joiner, K. A., 1994, In : Antimicrobial Agents and Chemotherapy. 38, 7, p. 1620-1627 8 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Structure and Function of the Parasitophorous Vacuole Membrane Surrounding Toxoplasma gondii

JOINER, K. A., BECKERS, C. J. M., BERMUDES, D., OSSORIO, P. N., SCHWAB, J. C. & DUBREMETZ, J. F., Sep 1994, In : Annals of the New York Academy of Sciences. 730, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Tandemly repeated genes encode nucleoside triphosphate hydrolase isoforms secreted into the parasitophorous vacuole of Toxoplasma gondii

Bermudes, D., Peck, K. R., Afifi, M. A., Beckers, C. J. M. & Joiner, K. A., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 29252-29260 9 p.

Research output: Contribution to journalArticle

140 Scopus citations
Open Access
281 Scopus citations

The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm

Beckers, C. J. M., Dubremetz, J. F., Mercereau-Puijalon, O. & Joiner, K. A., Nov 1994, In : Journal of Cell Biology. 127, 4, p. 947-961 15 p.

Research output: Contribution to journalArticle

194 Scopus citations

The type I macrophage scavenger receptor binds to Gram-positive bacteria and recognizes lipoteichoic acid

Dunne, D. W., Resnick, D., Greenberg, J., Krieger, M. & Joiner, K. A., Mar 1 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 5, p. 1863-1867 5 p.

Research output: Contribution to journalArticle

Open Access
288 Scopus citations
1995

Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii: Implications for the target of macrolide antibiotics

Beckers, C. J. M., Roos, D. S., Donald, R. G. K., Luft, B. J., Schwab, J. C., Cao, Y. & Joiner, K. A., Jan 1995, In : Journal of Clinical Investigation. 95, 1, p. 367-376 10 p.

Research output: Contribution to journalArticle

Open Access
98 Scopus citations

Toxoplasma gondii tachyzoites possess an unusual plasma membrane adenosine transporter

Conrad Schwab, J., Afifi Afifi, M., Pizzorno, G., Handschumacher, R. E. & Joiner, K. A., Mar 1995, In : Molecular and Biochemical Parasitology. 70, 1-2, p. 59-69 11 p.

Research output: Contribution to journalArticle

45 Scopus citations
1996

Influence of lipoteichoic acid structure on recognition by the macrophage scavenger receptor

Greenberg, J. W., Fischer, W. & Joiner, K. A., 1996, In : Infection and Immunity. 64, 8, p. 3318-3325 8 p.

Research output: Contribution to journalArticle

Open Access
106 Scopus citations

Interactions of human mannose-binding protein with lipoteichoic acids

Polotsky, V. Y., Fischer, W., Ezekowitz, R. A. B. & Joiner, K. A., Jan 8 1996, In : Infection and Immunity. 64, 1, p. 380-383 4 p.

Research output: Contribution to journalArticle

52 Scopus citations

Structure and function of the Toxoplasma gondii vacuole

Joiner, K. A., Bermudes, D., Sinai, A., Qi, H., Polotsky, V. & Beckers, C. J. M., Jan 1 1996, In : Annals of the New York Academy of Sciences. 797, p. 1-7 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
1997
233 Scopus citations
Open Access
38 Scopus citations

Different fractional domains in the parasitophorous vacuole membrane of Toxoplasma gondii

Samuel, B. U., Qi, H., Ardito, T., Ngo, H., Kashgarian, M. & Joiner, K. A., Dec 1 1997, In : Clinical Infectious Diseases. 25, 2, 1 p.

Research output: Contribution to journalArticle

Erratum: (Journal of Clinical Investigation (April 1997) 99:8 (1814- 1817))

Joiner, K. A., Jan 1 1997, In : Journal of Clinical Investigation. 100, 3, 1 p.

Research output: Contribution to journalComment/debate

Interaction of human mannose-binding protein with Mycobacterium avium

Polotsky, V. Y., Belisle, J. T., Mikusova, K., Ezekowitz, R. A. B. & Joiner, K. A., Jan 1 1997, In : Journal of Infectious Diseases. 175, 5, p. 1159-1168 10 p.

Research output: Contribution to journalArticle

Open Access
72 Scopus citations

Membrane-protein traffic in pathogen-infected cells

Joiner, K. A., Apr 15 1997, In : Journal of Clinical Investigation. 99, 8, p. 1814-1817 4 p.

Research output: Contribution to journalReview article

Open Access
20 Scopus citations

Membrane-protein traffic in pathogen-infected cells

Joiner, K. A., Dec 1 1997, In : Journal of Clinical Investigation. 100, 12 SUPPL., p. S25-S27

Research output: Contribution to journalReview article

Safe haven: The cell biology of nonfusogenic pathogen vacuoles

Sinai, A. P. & Joiner, K. A., 1997, In : Annual review of microbiology. 51, p. 415-462 48 p.

Research output: Contribution to journalReview article

186 Scopus citations

Targeting of proteins in the parasitophorous vacuolar space of Toxoplasma gondii

Samuel, B. U., Ngo, H., Qi, H., Dubremetz, J. F. & Joiner, K. A., Dec 1 1997, In : Clinical Infectious Diseases. 25, 2, 1 p.

Research output: Contribution to journalArticle

Targeting the secretory pathway of Toxoplasma gondii

Karsten, V., Qi, H., Beckers, C. J. & Joiner, K. A., Oct 1997, In : Methods: A Companion to Methods in Enzymology. 13, 2, p. 103-111 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

The expression of Toxoplasma proteins in Neospora caninum and the identification of a gene encoding a novel rhoptry protein

Beckers, C. J. M., Wakefield, T. & Joiner, K. A., Nov 1 1997, In : Molecular and Biochemical Parasitology. 89, 2, p. 209-223 15 p.

Research output: Contribution to journalArticle

50 Scopus citations
1998

Basis for substrate specificity of the Toxoplasma gondii nucleoside triphosphate hydrolase

Nakaar, V., Beckers, C. J. M., Polotsky, V. & Joiner, K. A., Nov 30 1998, In : Molecular and Biochemical Parasitology. 97, 1-2, p. 209-220 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

Fellowship training in infectious diseases: A report from the regional and national meetings of infectious diseases division chiefs and program directors

Joiner, K. A., Powderly, W. G., Blaser, M. J., Klempner, M. S., Locksley, R. M., Mandell, G. L., Preheim, L. C., Remington, J. S., Slama, T. G., Steigbigel, N. H. & Bartlett, J. G., May 25 1998, In : Clinical Infectious Diseases. 26, 5, p. 1060-1065 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Induced activation of the Toxoplasma gondii nucleoside triphosphate hydrolase leads to depletion of host cell ATP levels and rapid exit of intracellular parasites from infected cells

Silverman, J. A., Qi, H., Riehl, A., Beckers, C., Nakaar, V. & Joiner, K. A., May 15 1998, In : Journal of Biological Chemistry. 273, 20, p. 12352-12359 8 p.

Research output: Contribution to journalArticle

67 Scopus citations

The parasitophorous vacuole membrane surrounding Plasmodium and Toxoplasma: An unusual compartment in infected cells

Lingelbach, K. & Joiner, K. A., Jul 8 1998, In : Journal of Cell Science. 111, 11, p. 1467-1475 9 p.

Research output: Contribution to journalArticle

213 Scopus citations

The protozoan parasite Toxoplasma gondii targets proteins to dense granules and the vacuolar space using both conserved and unusual mechanisms

Karsten, V., Qi, H., Beckers, C. J. M., Reddy, A., Dubremetz, J. F., Webster, P. & Joiner, K. A., Jun 15 1998, In : Journal of Cell Biology. 141, 6, p. 1323-1333 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Upstream elements required for expression of nucleoside triphosphate hydrolase genes of Toxoplasma gondii

Nakaar, V., Bermudes, D., Peck, K. R. & Joiner, K. A., May 1 1998, In : Molecular and Biochemical Parasitology. 92, 2, p. 229-239 11 p.

Research output: Contribution to journalArticle

48 Scopus citations
1999

Constitutive calcium-independent release of Toxoplasma gondii dense granules occurs through the NSF/SNAP/SNARE/Rab machinery

Chaturvedi, S., Qi, H., Coleman, D., Rodriguez, A., Hanson, P. I., Striepen, B., Roos, D. S. & Joiner, K. A., Jan 22 1999, In : Journal of Biological Chemistry. 274, 4, p. 2424-2431 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

En route to the vacuole. Tracing the secretory pathway of Toxoplasma gondii

Stedman, T. T. & Joiner, K. A., Dec 1 1999, In : Advances in Cellular and Molecular Biology of Membranes and Organelles. 6, C, p. 233-261 29 p.

Research output: Contribution to journalReview article

13 Scopus citations
Open Access
6 Scopus citations

Targeted reduction of nucleoside triphosphate hydrolase by antisense RNA inhibits Toxoplasma gondii proliferation

Nakaar, V., Samuel, B. U., Ngo, E. O. & Joiner, K. A., Feb 19 1999, In : Journal of Biological Chemistry. 274, 8, p. 5083-5087 5 p.

Research output: Contribution to journalArticle

60 Scopus citations

The expression and distribution of dense granule proteins in the enteric (coccidian) forms of Toxoplasma gondii in the small intestine of the cat

Ferguson, D. J. P., Cesbron-Delauw, M. F., Dubremetz, J. F., Sibley, L. D., Joiner, K. A. & Wright, S., Mar 1999, In : Experimental parasitology. 91, 3, p. 203-211 9 p.

Research output: Contribution to journalArticle

44 Scopus citations
2000

Coinfection of fibroblasts with Coxiella burnetti and Toxoplasma gondii: To each their own

Sinai, A. P., Paul, S., Rabinovitch, M., Kaplan, G. & Joiner, K. A., Jun 2000, In : Microbes and Infection. 2, 7, p. 727-736 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
19 Scopus citations

Differential sorting and post-secretory targeting of proteins in parasitic invasion

Ngô, H. M., Hoppe, H. C. & Joiner, K. A., Feb 1 2000, In : Trends in Cell Biology. 10, 2, p. 67-72 6 p.

Research output: Contribution to journalReview article

54 Scopus citations