• 985 Citations
  • 17 h-Index
19992018

Research output per year

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Research Output

  • 985 Citations
  • 17 h-Index
  • 21 Article
  • 1 Comment/debate
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Article
2018

Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition

Tang, H., Babicheva, A., McDermott, K., Gu, Y., Ayon, R. J., Song, S., Wang, Z., Gupta, A., Zhou, T., Sun, X., Dash, S., Wang, Z., Balistrieri, A., Zheng, Q., Cordery, A. G., Desai, A., Rischard, F., Khalpey, Z. I., Wang, J., Black, S. M. & 3 others, Garcia, J. GN., Makino, A. & Yuan, J., Feb 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 2, p. L256-L275

Research output: Contribution to journalArticle

34 Scopus citations

STIM2 (Stromal Interaction Molecule 2)–mediated increase in resting cytosolic free Ca2+ concentration stimulates PASMC proliferation in pulmonary arterial hypertension

Song, S., Carr, S. G., McDermott, K., Rodriguez, M., Babicheva, A., Balistrieri, A., Ayon, R. J., Wang, J., Makino, A. & Yuan, J., Jan 1 2018, In : Hypertension. 71, 3, p. 518-529 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH

Song, S., Ayon, R. J., Yamamura, A., Yamamura, H., Dash, S., Babicheva, A., Tang, H., Sun, X., Cordery, A. G., Khalpey, Z. I., Black, S. M., Desai, A., Rischard, F., McDermott, K., Garcia, J. GN., Makino, A. & Yuan, J., Mar 1 2017, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 312, 3, p. L309-L325

Research output: Contribution to journalArticle

9 Scopus citations

Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia-induced pulmonary hypertension

Wu, K., Zhang, Q., Wu, X., Lu, W., Tang, H., Liang, Z., Gu, Y., Song, S., Ayon, R. J., Wang, Z., McDermott, K., Balistrieri, A., Wang, C., Black, S. M., Garcia, J. GN., Makino, A., Yuan, J. & Wang, J., Nov 1 2017, In : British Journal of Pharmacology. 174, 22, p. 4155-4172 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

Inhibition of ciliogenesis promotes Hedgehog signaling, tumorigenesis, and metastasis in breast cancer

Hassounah, N. B., Nunez, M., Fordyce, C., Roe, D., Nagle, R. B., Bunch, T. & McDermott, K., Oct 1 2017, In : Molecular Cancer Research. 15, 10, p. 1421-1430 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
2016

ATP promotes cell survival via regulation of cytosolic [Ca2+] and Bcl-2/Bax ratio in lung cancer cells

Song, S., Jacobson, K. N., McDermott, K., Reddy, S. P., Cress, A. E., Tang, H., Dudek, S. M., Black, S. M., Garcia, J. GN., Makino, A. & Yuan, J., Jan 15 2016, In : American Journal of Physiology - Cell Physiology. 310, 2, p. C99-C114

Research output: Contribution to journalArticle

35 Scopus citations
2014

Loss of primary cilia occurs early in breast cancer development

Menzl, I., Lebeau, L., Pandey, R., Hassounah, N. B., Li, F. W., Nagle, R., Weihs, K. & McDermott, K. M., Jan 1 2014, In : Cilia. 3, 1, 7.

Research output: Contribution to journalArticle

59 Scopus citations
2013

Primary Cilia Are Lost in Preinvasive and Invasive Prostate Cancer

Hassounah, N. B., Nagle, R., Saboda, K., Roe, D. J., Dalkin, B. L. & McDermott, K. M., Jul 2 2013, In : PloS one. 8, 7, e68521.

Research output: Contribution to journalArticle

62 Scopus citations
2012

Molecular pathways: The role of primary cilia in cancer progression and therapeutics with a focus on hedgehog signaling

Hassounah, N. B., Bunch, T. A. & McDermott, K. M., May 1 2012, In : Clinical Cancer Research. 18, 9, p. 2429-2435 7 p.

Research output: Contribution to journalArticle

84 Scopus citations
2010

Primary Cilia Regulate Branching Morphogenesis during Mammary Gland Development

McDermott, K. M., Liu, B. Y., Tlsty, T. D. & Pazour, G. J., Apr 27 2010, In : Current Biology. 20, 8, p. 731-737 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
2009

Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy

Dumont, N., Crawford, Y. G., Sigaroudinia, M., Nagrani, S. S., Wilson, M. B., Buehring, G. C., Turashvili, G., Aparicio, S., Gauthier, M. L., Fordyce, C. A., McDermott, K. M. & Tlsty, T. D., Dec 8 2009, In : Breast Cancer Research. 11, 6, R87.

Research output: Contribution to journalArticle

25 Scopus citations
2007

MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion

Swanson, B. J., McDermott, K. M., Singh, P. K., Eggers, J. P., Crocker, P. R. & Hollingsworth, M. A., Nov 1 2007, In : Cancer Research. 67, 21, p. 10222-10229 8 p.

Research output: Contribution to journalArticle

61 Scopus citations
2006

p16INK4a prevents centrosome dysfunction and genomic instability in primary cells

McDermott, K. M., Zhang, J., Holst, C. R., Kozakiewicz, B. K., Singla, V. & Tlsty, T. D., Mar 1 2006, In : PLoS biology. 4, 3, p. 350-365 16 p.

Research output: Contribution to journalArticle

103 Scopus citations
2005

Genetic and epigenetic changes in mammary epithelial cells identify a subpopulation of cells involved in early carcinogenesis

Berman, H., Zhang, J., Crawford, Y. G., Gauthier, M. L., Fordyce, C. A., McDermott, K. M., Sigaroudinia, M., Kozakiewicz, K. & Tlsty, T. D., Dec 1 2005, In : Cold Spring Harbor Symposia on Quantitative Biology. 70, p. 317-327 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae

Jambhekar, A., McDermott, K., Sorber, K., Shepard, K. A., Vale, R. D., Takizawa, P. A. & DeRisi, J. L., Dec 13 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 50, p. 18005-18010 6 p.

Research output: Contribution to journalArticle

51 Scopus citations
2004

Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis

Tlsty, T. D., Crawford, Y. G., Holst, C. R., Fordyce, C. A., Zhang, J., McDermott, K., Kozakiewicz, K. & Gauthier, M. L., Jul 1 2004, In : Journal of Mammary Gland Biology and Neoplasia. 9, 3, p. 263-274 12 p.

Research output: Contribution to journalArticle

66 Scopus citations
2003

The contribution of tandem repeat number to the O-glycosylation of mucins

Scott Silverman, H., Sutton-Smith, M., McDermott, K., Heal, P., Leir, S. H., Morris, H. R., Hollingsworth, M. A., Dell, A. & Harris, A., Apr 1 2003, In : Glycobiology. 13, 4, p. 265-277 13 p.

Research output: Contribution to journalArticle

32 Scopus citations
2001

Identification of MUC1 proteolytic cleavage sites in vivo

Parry, S., Silverman, H. S., McDermott, K., Willis, A., Hollingsworth, M. A. & Harris, A., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 283, 3, p. 715-720 6 p.

Research output: Contribution to journalArticle

107 Scopus citations

In vivo glycosylation of mucin tandem repeats

Silverman, H. S., Parry, S., Sutton-Smith, M., Burdick, M. D., McDermott, K., Reid, C. J., Batra, S. K., Morris, H. R., Hollingsworth, M. A., Dell, A. & Harris, A., Jan 1 2001, In : Glycobiology. 11, 6, p. 459-471 13 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Overexpression of MUC1 reconfigures the binding properties of tumor cells

McDermott, K. M., Crocker, P. R., Harris, A., Burdick, M. D., Hinoda, Y., Hayashi, T., Imai, K. & Hollingsworth, M. A., Dec 15 2001, In : International Journal of Cancer. 94, 6, p. 783-791 9 p.

Research output: Contribution to journalArticle

78 Scopus citations
1999

Phosphorylation of the kinase suppressor of Ras by associated kinases

Volle, D. J., Fulton, J. A., Chaika, O. V., McDermott, K., Huang, H., Steinke, L. A. & Lewis, R. E., Apr 20 1999, In : Biochemistry. 38, 16, p. 5130-5137 8 p.

Research output: Contribution to journalArticle

29 Scopus citations