Kristian Doyle

  • 1511 Citations
  • 16 h-Index
20032020

Research output per year

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Research Output

  • 1511 Citations
  • 16 h-Index
  • 26 Article
  • 2 Chapter
  • 2 Review article
  • 1 Editorial
2020

Immunological mechanisms in poststroke dementia

Doyle, K. P. & Buckwalter, M. S., Feb 1 2020, In : Current opinion in neurology. 33, 1, p. 30-36 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Preclinical evidence in support of repurposing sub-anesthetic ketamine as a treatment for L-DOPA-induced dyskinesia

Bartlett, M. J., Flores, A. J., Ye, T., Smidt, S. I., Dollish, H. K., Stancati, J. A., Farrell, D. C., Parent, K. L., Doyle, K. P., Besselsen, D. G., Heien, M. L., Cowen, S. L., Steece-Collier, K., Sherman, S. J. & Falk, T., Nov 2020, In : Experimental Neurology. 333, 113413.

Research output: Contribution to journalArticle

Open Access
2019
7 Scopus citations
2018

Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia

Nguyen, T. V. V., Hayes, M., Zbesko, J. C., Frye, J. B., Congrove, N. R., Belichenko, N. P., McKay, B. S., Longo, F. M. & Doyle, K. P., Sep 24 2018, In : Acta neuropathologica communications. 6, 1, p. 100 1 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts

Zbesko, J. C., Nguyen, T. V. V., Yang, T., Frye, J. B., Hussain, O., Hayes, M., Chung, A., Day, W. A., Stepanovic, K., Krumberger, M., Mona, J., Longo, F. M. & Doyle, K. P., Apr 2018, In : Neurobiology of Disease. 112, p. 63-78 16 p.

Research output: Contribution to journalArticle

13 Scopus citations

Gut microbiota contributes to resistance against Pneumococcal Pneumonia in immunodeficient Ragl Mice

Felix, K. M., Jaimez, I. A., Nguyen, T. V. V., Ma, H., Raslan, W. A., Klinger, C. N., Doyle, K. P. & Wu, H. J. J., Apr 18 2018, In : Frontiers in Cellular and Infection Microbiology. 8, APR, 118.

Research output: Contribution to journalArticle

10 Scopus citations

Liquefaction of the brain following stroke shares a similar molecular and morphological profile with atherosclerosis and mediates secondary neurodegeneration in an osteopontin-dependent mechanism

Chung, A. G., Frye, J. B., Zbesko, J. C., Constantopoulos, E., Hayes, M., Figueroa, A. G., Becktel, D. A., Antony Day, W., Konhilas, J. P., McKay, B. S., Nguyen, T. V. V. & Doyle, K. P., Sep 1 2018, In : eNeuro. 5, 5, e0076-18.2018.

Research output: Contribution to journalArticle

6 Scopus citations

Suppressing interferon-γ stimulates microglial responses and repair of microbleeds in the diabetic brain

Taylor, S., Mehina, E., White, E., Reeson, P., Yongblah, K., Doyle, K. P. & Brown, C. E., Oct 3 2018, In : Journal of Neuroscience. 38, 40, p. 8707-8722 16 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse

Danilo, C. A., Constantopoulos, E., McKee, L. A., Chen, H., Regan, J. A., Lipovka, Y., Lahtinen, S., Stenman, L. K., Nguyen, T. V. V., Doyle, K. P., Slepian, M. J., Khalpey, Z. I. & Konhilas, J. P., 2017, In : Beneficial Microbes. 8, 2, p. 257-269 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Does B lymphocyte-mediated autoimmunity contribute to post-stroke dementia?

Doyle, K. P. & Buckwalter, M. S., Aug 2017, In : Brain, Behavior, and Immunity. 64, p. 1-8 8 p.

Research output: Contribution to journalReview article

17 Scopus citations

Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer's disease

Branca, C., Ferreira, E., Nguyen, T. V., Doyle, K., Caccamo, A. & Oddo, S., Dec 2017, In : Human molecular genetics. 26, 24, p. 4823-4835 13 p.

Research output: Contribution to journalArticle

23 Scopus citations
2016

Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue

Nguyen, T. V. V., Frye, J. B., Zbesko, J. C., Stepanovic, K., Hayes, M., Urzua, A., Serrano, G., Beach, T. G. & Doyle, K. P., Sep 6 2016, In : Acta neuropathologica communications. 4, 1, p. 100 1 p.

Research output: Contribution to journalArticle

17 Scopus citations

Unraveling the pathophysiology of chronic stroke lesions could yield treatments for stroke-related dementia

Doyle, K., Feb 1 2016, In : Future Neurology. 11, 1, p. 1-4 4 p.

Research output: Contribution to journalReview article

2015

B-lymphocyte-mediated delayed cognitive impairment following stroke

Doyle, K. P., Quach, L. N., Solé, M., Axtell, R. C., Nguyen, T. V. V., Soler-Llavina, G. J., Jurado, S., Han, J., Steinman, L., Longo, F. M., Schneider, J. A., Malenka, R. C. & Buckwalter, M. S., 2015, In : Journal of Neuroscience. 35, 5, p. 2133-2145 13 p.

Research output: Contribution to journalArticle

109 Scopus citations

Ferumoxytol administration does not alter infarct volume or the inflammatory response to stroke in mice

Doyle, K. P., Quach, L. N., Arceuil, H. E. D. & Buckwalter, M. S., Jan 1 2015, In : Neuroscience Letters. 584, p. 236-240 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

A mouse model of permanent focal ischemia: Distal middle cerebral artery occlusion

Doyle, K. & Buckwalter, M. S., 2014, Methods in Molecular Biology. Humana Press Inc., Vol. 1135. p. 103-110 8 p. (Methods in Molecular Biology; vol. 1135).

Research output: Chapter in Book/Report/Conference proceedingChapter

17 Scopus citations

A mouse model of permanent focal ischemia: Distal middle cerebral artery occlusion

Doyle, K. & Buckwalter, M. S., 2014, Methods in Molecular Biology. Humana Press Inc., Vol. 1135. p. 103-110 8 p. (Methods in Molecular Biology; vol. 1135).

Research output: Chapter in Book/Report/Conference proceedingChapter

Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice

Cekanaviciute, E., Fathali, N., Doyle, K. P., Williams, A. M., Han, J. & Buckwalter, M. S., Aug 2014, In : Glia. 62, 8, p. 1227-1240 14 p.

Research output: Contribution to journalArticle

82 Scopus citations
2012

Delayed administration of a small molecule tropomyosin-related kinase B ligand promotes recovery after hypoxic-ischemic stroke

Han, J., Pollak, J., Yang, T., Siddiqui, M. R., Doyle, K. P., Taravosh-Lahn, K., Cekanaviciute, E., Han, A., Goodman, J. Z., Jones, B., Jing, D., Massa, S. M., Longo, F. M. & Buckwalter, M. S., Jul 1 2012, In : Stroke. 43, 7, p. 1918-1924 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Distal hypoxic stroke: A new mouse model of stroke with high throughput, low variability and a quantifiable functional deficit

Doyle, K. P., Fathali, N., Siddiqui, M. R. & Buckwalter, M. S., May 30 2012, In : Journal of Neuroscience Methods. 207, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Stratification substantially reduces behavioral variability in the hypoxic-ischemic stroke model

Pollak, J., Doyle, K. P., Mamer, L., Shamloo, M. & Buckwalter, M. S., Sep 2012, In : Brain and Behavior. 2, 5, p. 698-706 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Testing the oxidative stress hypothesis of aging in primate fibroblasts: Is there a correlation between species longevity and cellular ROS production?

Csiszar, A., Podlutsky, A., Podlutskaya, N., Sonntag, W. E., Merlin, S. Z., Philipp, E. E. R., Doyle, K., Davila, A., Recchia, F. A., Ballabh, P., Pinto, J. T. & Ungvari, Z., Aug 1 2012, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 67 A, 8, p. 841-852 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

The double-edged sword of inflammation after stroke: What sharpens each edge?

Doyle, K. P. & Buckwalter, M. S., Jun 1 2012, In : Annals of Neurology. 71, 6, p. 729-731 3 p.

Research output: Contribution to journalEditorial

7 Scopus citations
2011

Proof of concept: Pharmacological preconditioning with a Toll-like receptor agonist protects against cerebrovascular injury in a primate model of stroke

Bahjat, F. R., Williams-Karnesky, R. L., Kohama, S. G., West, G. A., Doyle, K. P., Spector, M. D., Hobbs, T. R. & Stenzel-Poore, M. P., May 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 5, p. 1229-1242 14 p.

Research output: Contribution to journalArticle

40 Scopus citations
2010

TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

Doyle, K. P., Cekanaviciute, E., Mamer, L. E. & Buckwalter, M. S., Oct 11 2010, In : Journal of Neuroinflammation. 7, 62.

Research output: Contribution to journalArticle

129 Scopus citations
2009

A new model of cortical stroke in the rhesus macaque

West, G. A., Golshani, K. J., Doyle, K. P., Lessov, N. S., Hobbs, T. R., Kohama, S. G., Pike, M. M., Kroenke, C. D., Grafe, M. R., Spector, M. D., Tobar, E. T., Simon, R. P. & Stenzel-Poore, M. P., Jun 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 6, p. 1175-1186 12 p.

Research output: Contribution to journalArticle

41 Scopus citations
2008

Mechanisms of ischemic brain damage

Doyle, K. P., Simon, R. P. & Stenzel-Poore, M. P., Sep 1 2008, In : Neuropharmacology. 55, 3, p. 310-318 9 p.

Research output: Contribution to journalArticle

548 Scopus citations

Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke

Doyle, K. P., Yang, T., Lessov, N. S., Ciesielski, T. M., Stevens, S. L., Simon, R. P., King, J. S. & Stenzel-Poore, M. P., Jun 30 2008, In : Journal of Cerebral Blood Flow and Metabolism. 28, 6, p. 1235-1248 14 p.

Research output: Contribution to journalArticle

69 Scopus citations
2007

Novel thyroxine derivatives, thyronamine and 3-iodothyronamine, induce transient hypothermia and marked neuroprotection against stroke injury

Doyle, K. P., Suchland, K. L., Ciesielski, T. M. P., Lessov, N. S., Grandy, D. K., Scanlan, T. S. & Stenzel-Poore, M. P., Sep 1 2007, In : Stroke. 38, 9, p. 2569-2576 8 p.

Research output: Contribution to journalArticle

79 Scopus citations
2005

Neuroprotection by osteopontin in stroke

Meller, R., Stevens, S. L., Minami, M., Cameron, J. A., King, S., Rosenzweig, H., Doyle, K., Lessov, N. S., Simon, R. P. & Stenzel-Poore, M. P., Feb 1 2005, In : Journal of Cerebral Blood Flow and Metabolism. 25, 2, p. 217-225 9 p.

Research output: Contribution to journalArticle

144 Scopus citations
2003

Working with GFP in the brain

Doyle, K. P., Simon, R. P., Snyder, A. & Stenzel-Poore, M. P., Mar 1 2003, In : BioTechniques. 34, 3, p. 492-494 3 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations