Lalitha Madhavan

  • 674 Citations
  • 15 h-Index
20032019

Research output per year

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Research Output

  • 674 Citations
  • 15 h-Index
  • 22 Article
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Article
2019

Redox regulation by NRF2 in aging and disease

Schmidlin, C. J., Dodson, M. B., Madhavan, L. & Zhang, D., Jan 1 2019, (Accepted/In press) In : Free Radical Biology and Medicine.

Research output: Contribution to journalArticle

25 Scopus citations
2018

A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells

Ray, S., Corenblum, M. J., Anandhan, A., Reed, A., Ortiz, F. O., Zhang, D., Barnes, C. A. & Madhavan, L., Apr 1 2018, In : Cell Transplantation. 27, 4, p. 589-606 18 p.

Research output: Contribution to journalArticle

10 Scopus citations

Parkinson's disease skin fibroblasts display signature alterations in growth, redox homeostasis, mitochondrial function, and autophagy

Teves, J. M. Y., Bhargava, V., Kirwan, K. R., Corenblum, M. J., Justiniano, R., Wondrak, G. T., Anandhan, A., Flores, A. J., Schipper, D. A., Khalpey, Z. I., Sligh, J. E., Curiel, C. N., Sherman, S. J. & Madhavan, L., Jan 12 2018, In : Frontiers in Neuroscience. 11, JAN, 737.

Research output: Contribution to journalArticle

17 Scopus citations
2017

Small-scale propagation of human iPSCS in serum-free conditions for routine immunocytochemical characterization

Corenblum, M. J. & Madhavan, L., Feb 18 2017, In : Journal of Visualized Experiments. 2017, 120, e55260.

Research output: Contribution to journalArticle

2016

Effects of the iron oxide nanoparticle Molday ION Rhodamine B on the viability and regenerative function of neural stem cells: Relevance to clinical translation

Umashankar, A., Corenblum, M. J., Ray, S., Valdez, M., Yoshimaru, E. S., Trouard, T. P. & Madhavan, L., Apr 27 2016, In : International Journal of Nanomedicine. 11, p. 1731-1748 18 p.

Research output: Contribution to journalArticle

16 Scopus citations

Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle-age period

Corenblum, M. J., Ray, S., Remley, Q. W., Long, M., Harder, B., Zhang, D., Barnes, C. A. & Madhavan, L., Aug 1 2016, In : Aging Cell. 15, 4, p. 725-736 12 p.

Research output: Contribution to journalArticle

28 Scopus citations
2015

Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism

Paumier, K. L., Sortwell, C. E., Madhavan, L., Terpstra, B., Celano, S. L., Green, J. J., Imus, N. M., Marckini, N., Daley, B., Steece-Collier, K. & Collier, T. J., 2015, In : Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 40, 4, p. 874-883 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Redox-based regulation of neural stem cell function and Nrf2

Madhavan, L., Aug 1 2015, In : Biochemical Society Transactions. 43, p. 627-631 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Sonic hedgehog controls the phenotypic fate and therapeutic efficacy of grafted neural precursor cells in a model of nigrostriatal neurodegeneration

Madhavan, L., Daley, B. F., Davidson, B. L., Boudreau, R. L., Lipton, J. W., Cole-Strauss, A., Steece-Collier, K. & Collier, T. J., Sep 4 2015, In : PLoS One. 10, 9, e0137136.

Research output: Contribution to journalArticle

4 Scopus citations

Systemic human CD34<sup>+</sup> cells populate the brain and activate host mechanisms to counteract nigrostriatal degeneration

Corenblum, M. J., Flores, A. J., Badowski, M., Harris, D. T. & Madhavan, L., Aug 1 2015, In : Regenerative Medicine. 10, 5, p. 563-577 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Tricyclic antidepressant treatment evokes regional changes in neurotrophic factors over time within the intact and degenerating nigrostriatal system

Paumier, K. L., Sortwell, C. E., Madhavan, L., Terpstra, B., Daley, B. F. & Collier, T. J., Apr 1 2015, In : Experimental Neurology. 266, p. 11-21 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2012

Endogenous neural precursors influence grafted neural stem cells and contribute to neuroprotection in the parkinsonian rat

Madhavan, L., Daley, B. F., Sortwell, C. E. & Collier, T. J., Mar 2012, In : European Journal of Neuroscience. 35, 6, p. 883-895 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model

Gombash, S. E., Lipton, J. W., Collier, T. J., Madhavan, L., Steece-Collier, K., Cole-Strauss, A., Terpstra, B. T., Spieles-Engemann, A. L., Daley, B. F., Wohlgenant, S. L., Thompson, V. B., Manfredsson, F. P., Mandel, R. J. & Sortwell, C. E., Mar 2012, In : Molecular Therapy. 20, 3, p. 544-554 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Tricyclic antidepressants delay the need for dopaminergic therapy in early Parkinson's disease

Paumier, K. L., Siderowf, A. D., Auinger, P., Oakes, D., Madhavan, L., Espay, A. J., Revilla, F. J. & Collier, T. J., 2012, In : Movement Disorders. 27, 7, p. 880-887 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

Transfer of host-derived alpha synuclein to grafted dopaminergic neurons in rat

Kordower, J. H., Dodiya, H. B., Kordower, A. M., Terpstra, B., Paumier, K., Madhavan, L., Sortwell, C., Steece-Collier, K. & Collier, T. J., Sep 2011, In : Neurobiology of Disease. 43, 3, p. 552-557 6 p.

Research output: Contribution to journalArticle

112 Scopus citations
2010

A synergistic approach for neural repair: Cell transplantation and induction of endogenous precursor cell activity

Madhavan, L. & Collier, T. J., May 2010, In : Neuropharmacology. 58, 6, p. 835-844 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Stimulation of the rat subthalamic nucleus is neuroprotective following significant nigral dopamine neuron loss

Spieles-Engemann, A. L., Behbehani, M. M., Collier, T. J., Wohlgenant, S. L., Steece-Collier, K., Paumier, K., Daley, B. F., Gombash, S., Madhavan, L., Mandybur, G. T., Lipton, J. W., Terpstra, B. T. & Sortwell, C. E., Jul 2010, In : Neurobiology of Disease. 39, 1, p. 105-115 11 p.

Research output: Contribution to journalArticle

79 Scopus citations
2009

Transplantation of subventricular zone neural precursors induces an endogenous precursor cell response in a rat model of Parkinson's disease

Madhavan, L., Daley, B. F., Paumier, K. I. & Collier, T. J., Jul 1 2009, In : Journal of Comparative Neurology. 515, 1, p. 102-115 14 p.

Research output: Contribution to journalArticle

53 Scopus citations
2008

Neural stem/progenitor cells initiate the formation of cellular networks that provide neuroprotection by growth factor-modulated antioxidant expression

Madhavan, L., Ourednik, V. & Ourednik, J., Jan 2008, In : Stem Cells. 26, 1, p. 254-265 12 p.

Research output: Contribution to journalArticle

80 Scopus citations
2006

Increased "vigilance" of antioxidant mechanisms in neural stem cells potentiates their capability to resist oxidative stress

Madhavan, L., Ourednik, V. & Ourednik, J., 2006, In : Stem Cells. 24, 9, p. 2110-2119 10 p.

Research output: Contribution to journalArticle

60 Scopus citations
2005

Grafted neural stem cells shield the host environment from oxidative stress

Madhavan, L., Ourednik, V. & Ourednik, J., 2005, In : Annals of the New York Academy of Sciences. 1049, p. 185-188 4 p.

Research output: Contribution to journalArticle

18 Scopus citations
2003

5-Hydroxytryptamine 1A receptor activation protects against N-methyl-D-aspartate-induced apoptotic cell death in striatal and mesencephalic cultures

Madhavan, L., Freed, W. J., Anantharam, V. & Kanthasamy, A. G., Mar 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 304, 3, p. 913-923 11 p.

Research output: Contribution to journalArticle

47 Scopus citations