Projects per year
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Projects
CANCER CENTER SUPPORT GRANT
Davis, T. P., Hersh, E. M., Weinstein, R. S., Miesfeld, R., Miller, T. P., Tsaprailis, G., Lynch, R., Chow, H., Nagle, R. B., Watts, G. S., Thomson, C., Roe, D., Stratton, S. P., Alberts, D. S., Hurley, L., Baker, A. F., Livingston, R. B., Dorr, R. T., Cress, A. E., Briehl, M. M., Mash, E. A., Duffy, J., Jones, S., Leibovitz, A., Meyskens, F., Moon, T., Trent, J., Newkirk, D., Von Hoff, D., Mount, D., Doetschman, T., Liebler, D., Marshall, J., McGovern, K., Grogan, T., Kraft, A., Powis, G., Peng, Y., Gerner, E., Aickin, M., Ritenbaugh, C., Taylor, C., Powell, M. B., Bowden, T., Taetle, R., Salmon, S., Ignatenko, N., Bhattacharyya, A. K., Futscher, B. W., Barton, J. K., Montfort, W. "., Roe, D., Garland, L. L., Doetschman, T. C., Kraft, A., Chow, H., Ellis, N. & Zeng, Y. -.
9/1/78 → 6/30/21
Project: Research project
The Development of Novel Inhibitors of BCL2 Gene Expression as Anticancer Therape
Siddiqui-Jain, A. & Hurley, L.
9/20/14 → 2/29/16
Project: Research project
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??
7/1/10 → 4/30/16
Project: Research project
Research Output
Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex
Miranti, C. K., Moore, S., Kim, Y., Chappeta, V. R., Wu, K., De, B., Gokhale, V., Hurley, L. H. & Reyes-Reyes, E. M., May 12 2020, In : Oncotarget. 11, 19, p. 1758-1776 19 p.Research output: Contribution to journal › Article
Open Access
In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
Montoya, J. J., Turnidge, M. A., Wai, D. H., Patel, A. R., Lee, D. W., Gokhale, V., Hurley, L. H., Arceci, R. J., Wetmore, C. & Azorsa, D. O., Dec 27 2019, In : BMC Cancer. 19, 1, 1251.Research output: Contribution to journal › Article
Open Access
1
Scopus
citations
Small-Molecule-Targeting Hairpin Loop of hTERT Promoter G-Quadruplex Induces Cancer Cell Death
Song, J. H., Kang, H. J., Luevano, L. A., Gokhale, V., Wu, K., Pandey, R., Chow, H-H., Hurley, L. & Kraft, A., Aug 15 2019, In : Cell Chemical Biology. 26, 8, p. 1110-1121.e4Research output: Contribution to journal › Article
4
Scopus
citations
TGF-β-induced fibrotic stress increases G-quadruplex formation in human fibroblasts
Toshniwal, P., Nguyen, M., Guédin, A., Viola, H., Ho, D., Kim, Y., Bhatt, U., Bond, C. S., Hool, L., Hurley, L. H., Mergny, J. L., Fear, M., Wood, F., Iyer, S. K. & Smith, N. M., Nov 1 2019, In : FEBS Letters. 593, 22, p. 3149-3161 13 p.Research output: Contribution to journal › Article
1
Scopus
citations
HMGB1 binds to the KRAS promoter G-quadruplex: A new player in oncogene transcriptional regulation?
Amato, J., Madanayake, T. W., Iaccarino, N., Novellino, E., Randazzo, A., Hurley, L. H. & Pagano, B., Jan 1 2018, In : Chemical Communications. 54, 68, p. 9442-9445 4 p.Research output: Contribution to journal › Article
10
Scopus
citations