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  • 6 Similar Profiles
DNA Chemical Compounds
G-Quadruplexes Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
CC 1065 Medicine & Life Sciences
Anti-Bacterial Agents Medicine & Life Sciences
Anthramycin Medicine & Life Sciences
Molecules Chemical Compounds
Telomerase Medicine & Life Sciences

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Projects 1978 2021

CANCER CENTER SUPPORT GRANT

Davis, T. P., Hersh, E. M., Weinstein, R. S., Miesfeld, R., Miller, T. P., Tsaprailis, G., Lynch, R., Chow, H., Nagle, R. B., Watts, G. S., Thomson, C., Roe, D., Stratton, S. P., Alberts, D. S., Hurley, L., Baker, A. F., Livingston, R. B., Dorr, R. T., Cress, A. E., Briehl, M. M., Mash, E. A., Duffy, J., Jones, S., Leibovitz, A., Meyskens, F., Moon, T., Trent, J., Newkirk, D., Von Hoff, D., Mount, D., Doetschman, T., Liebler, D., Marshall, J., McGovern, K., Grogan, T., Kraft, A., Powis, G., Peng, Y., Gerner, E., Aickin, M., Ritenbaugh, C., Taylor, C., Powell, M. B., Bowden, T., Taetle, R., Salmon, S., Ignatenko, N., Bhattacharyya, A. K., Futscher, B. W., Barton, J. K., Montfort, W. "., Roe, D., Garland, L. L., Doetschman, T. C., Kraft, A. & Chow, H.

National Institutes of Health

9/1/786/30/21

Project: Research projectCenter Core Grants

Neoplasms
Research
Research Personnel
Pharmaceutical Services
Clinical Trials

The Development of Novel Inhibitors of BCL2 Gene Expression as Anticancer Therape

Hurley, L. & Siddiqui-Jain, A.

National Institutes of Health

9/20/142/29/16

Project: Research projectSmall Business Innovation Research Grants (SBIR) - Phase I

Gene Expression
Neoplasms
Pharmaceutical Preparations
Drug Therapy
IMC-76
G-Quadruplexes
Platelet-Derived Growth Factor beta Receptor
platelet-derived growth factor receptor beta
promoter regions
Arteriosclerosis
G-Quadruplexes
Drug Delivery Systems
Gene Expression
Neoplasms
Transcriptional Silencer Elements

SPORE in Gastrointestinal Cancer

Roe, D., Einspahr, J. G., Bhattacharyya, A. K., Hurley, L., Nelson, M. A., Dragovich, T., Garewal, H. S., Von Hoff, D., Akporiaye, E., Mount, D., Gerner, E., Powis, G., Green, S. B. & Dvorak, K.

National Institutes of Health

9/5/023/31/15

Project: Research projectSpecialized Center

Research
Gastrointestinal Neoplasms
Neoplasms
Drug Delivery Systems
G-Quadruplexes

Research Output 1969 2017

  • 18653 Citations
  • 71 h-Index
  • 269 Article
  • 3 Chapter
  • 1 Comment/debate
5 Citations

Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA

Weldon, C., Behm-Ansmant, I., Hurley, L. H., Burley, G. A., Branlant, C., Eperon, I. C. & Dominguez, C. Jan 1 2017 In : Nature Chemical Biology. 13, 1, p. 18-20 3 p.

Research output: Research - peer-reviewArticle

G-Quadruplexes
RNA
7-deazaguanine
Biological Phenomena
RNA Precursors
3 Citations

Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression

Kaiser, C. E., Van Ert, N. A., Agrawal, P., Chawla, R., Yang, D. & Hurley, L. H. Jun 28 2017 In : Journal of the American Chemical Society. 139, 25, p. 8522-8536 15 p.

Research output: Research - peer-reviewArticle

Heterogeneous-Nuclear Ribonucleoprotein K
Transcription
Gene expression
Genes
DNA
2 Citations

Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma

Liang, W. S. , Hendricks, W. , Kiefer, J. , Schmidt, J. , Sekar, S. , Carpten, J. , Craig, D. W. , Adkins, J. , Cuyugan, L. , Manojlovic, Z. , Halperin, R. F. , Helland, A. , Nasser, S. , Legendre, C. , Hurley, L. H. , Sivaprakasam, K. , Johnson, D. B. , Crandall, H. , Busam, K. J. , Zismann, V. & 6 others Deluca, V., Lee, J., Sekulic, A., Ariyan, C. E., Sosman, J. & Trent, J. Apr 1 2017 In : Genome Research. 27, 4, p. 524-532 9 p.

Research output: Research - peer-reviewArticle

Melanoma
Extremities
Skin
Mutation
Therapeutics
1 Citations
G-Quadruplexes
Lymphoma, Large B-Cell, Diffuse
B-Cell Lymphoma
Drug Delivery Systems
Growth
2 Citations
G-Quadruplexes
Platelet-Derived Growth Factor beta Receptor
Down-Regulation
Gene Expression
Mutation