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Laurence Hurley

  • 22045 Citations
  • 77 h-Index
1969 …2020

Research output per year

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Research Output

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Comment/debate
1992

Erratum: The antitumor agent CC-1065 inhibits helicase-catalyzed unwinding of duplex DNA (Biochemistry (April 28, 1992) 31:16 (3968-3975))

Maine, I. P., Sun, D., Hurley, L. H. & Kodadek, T., Dec 1 1992, In : Biochemistry. 31, 43, 1 p.

Research output: Contribution to journal › Comment/debate

1993

Additions and Corrections: Analysis of the Monoalkylation and Cross-Linking Sequence Specificity of Bizelesin, a Bifunctional Alkylation Agent Related to (+)-CC-1065 (J. Am. Chem. Soc., (1993) 115(20)(9355))

Sun, D. & Hurley, L., Oct 1 1993, In : Journal of the American Chemical Society. 115, 20, p. 9355 1 p.

Research output: Contribution to journal › Comment/debate

2 Scopus citations
1994

(+)-CC-1065 as a structural probe of mu transposase-induced bending of DNA: Overcoming limitations of hydroxyl-radical footprinting

Ding, Z. M., Harshey, R. M. & Hurley, L. H., Jan 25 1994, In : Nucleic acids research. 22, 2, 1 p.

Research output: Contribution to journal › Comment/debate

1995

Additions and Corrections: Comparison of a DSB-120 DNA interstrand crosslinked adduct with the corresponding bis-tomaymycin adduct: An example of a successful template-directed approach to drug design based upon the monoalkylating compound tomaymycin (Journal of Medicinal Chemistry (1994) 37(19) (3132–3140)(10.1021/jm00045a019))

Mountzouris, J. A., Wang, J. J., Thurston, D. & Hurley, L. H., Mar 1 1995, In : Journal of Medicinal Chemistry. 38, 6, 1 p.

Research output: Contribution to journal › Comment/debate

Molecular struggle for transcriptional control

Henderson, D. & Hurley, S. L. H., Jun 1995, In : Nature Medicine. 1, 6, p. 525-527 3 p.

Research output: Contribution to journal › Comment/debate

69 Scopus citations
1996

Erratum: Cross-linkage by 'intact' bizelesin and bisalkylation by the 'separated halves' of the bizelesin dimer: Contrasting drug manipulation of DNA conformation (5'-TAATTA-3') directs alkylation toward different adenine targets (J. Am. Chem. Soc. 1996, 118, 5383-5395)

Seaman, F. C., Chu, J. & Hurley, L., Jan 1 1996, In : Journal of the American Chemical Society. 118, 33, 1 p.

Research output: Contribution to journal › Comment/debate

1 Scopus citations
1997

Inhibition of human telomerase by a G-Quadruplex-Interactive compound

Sun, D., Thompson, B., Cathers, B. E., Salazar, M., Kerwin, S. M., Trent, J. O., Jenkins, T. C., Neidle, S. & Hurley, L. H., Jul 18 1997, In : Journal of Medicinal Chemistry. 40, 14, p. 2113-2116 4 p.

Research output: Contribution to journal › Comment/debate

631 Scopus citations
1998

Erratum: Mechanism for the catalytic activation of ecteinascidin 743 and its subsequent alkylation of guanine N2 (Journal of the American Chemical Society (1998) 120 (2490-91))

Moore, B. M., Seaman, F. C., Wheelhouse, R. T. & Hurley, L. H., Sep 30 1998, In : Journal of the American Chemical Society. 120, 38, 1 p.

Research output: Contribution to journal › Comment/debate

5 Scopus citations

Erratum: A facile synthesis of 5-mesyl-3-benzylbenze[e]indole: Implications for the involvement of a p-quinone methide intermediate (Journal of Organic Chemistry (1998) 63 (5724))

Kshirsagar, T. A. & Hurley, L. H., Dec 11 1998, In : Journal of Organic Chemistry. 63, 25, 1 p.

Research output: Contribution to journal › Comment/debate

Open Access
2004

Erratum: The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent (Chemistry and Biology 8 (1033-1049))

Zewail-Foote, M., Li, V. S., Kohn, H., Bearss, D., Guzman, M. & Hurley, L. H., Feb 2004, In : Chemistry and Biology. 11, 2, 1 p.

Research output: Contribution to journal › Comment/debate

1 Scopus citations
2005

Erratum (Retracted Article): Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue (Proceedings of the National Academy of Sciences of the United States of America (April 20, 2004) 101:16 (6140-6145))

Grand, C. L., Powell, T. J., Nagle, R. B., Bearss, D. J., Tye, D., Gleason-Guzman, M. & Hurley, L. H., Jan 11 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 2, 1 p.

Research output: Contribution to journal › Comment/debate

7 Scopus citations