• 6377 Citations
  • 43 h-Index
1973 …2019
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Fingerprint Dive into the research topics where Leslie Gunatilaka is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Celastraceae Medicine & Life Sciences
Fungi Chemical Compounds
Alkaloids Chemical Compounds
Nuclear magnetic resonance Chemical Compounds
Cells Chemical Compounds
Biological Products Medicine & Life Sciences
Endophytes Medicine & Life Sciences
Metabolites Chemical Compounds

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Research Output 1973 2019

  • 6377 Citations
  • 43 h-Index
  • 218 Article
  • 2 Chapter
  • 1 Comment/debate
  • 1 Review article
1 Citation (Scopus)

(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels

Cai, S., Bellampalli, S. S., Yu, J., Li, W., Ji, Y., Wijeratne, E. M. K., Dorame, A., Luo, S., Shan, Z., Khanna, M., Moutal, A., Streicher, J. M., Gunatilaka, L. & Khanna, R., Mar 20 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1716-1728 13 p.

Research output: Contribution to journalArticle

Sodium Channels
Tetrodotoxin
Calcium Channels
Chronic Pain
Voltage-Gated Sodium Channels
4 Citations (Scopus)

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels

Bellampalli, S. S., Ji, Y., Moutal, A., Cai, S., Wijeratne, E. M. K., Gandini, M. A., Yu, J., Chefdeville, A., Dorame, A., Chew, L. A., Madura, C. L., Luo, S., Molnar, G., Khanna, M., Streicher, J. M., Zamponi, G. W., Gunatilaka, L. & Khanna, R., Jan 1 2019, In : Pain. 160, 1, p. 117-135 19 p.

Research output: Contribution to journalArticle

Hyptis
T-Type Calcium Channels
N-Type Calcium Channels
Lavandula
Peripheral Nervous System Diseases

Rational Reprogramming of O-Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds

Wang, X., Wang, C., Duan, L., Zhang, L., Liu, H., Xu, Y. M., Liu, Q., Mao, T., Zhang, W., Chen, M., Lin, M., Gunatilaka, L., Xu, Y. & Molnar, I., Mar 13 2019, In : Journal of the American Chemical Society. 141, 10, p. 4355-4364 10 p.

Research output: Contribution to journalArticle

Open Access
Regioselectivity
Methylation
Lactones
Drug Discovery
Scaffolds

Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels

Shan, Z., Cai, S., Yu, J., Zhang, Z., Vallecillo, T. G. M., Serafini, M. J., Thomas, A. M., Pham, N. Y. N., Bellampalli, S. S., Moutal, A., Zhou, Y., Xu, G. B., Xu, Y. M., Luo, S., Patek, M., Streicher, J. M., Gunatilaka, L. & Khanna, R., Jun 19 2019, In : ACS Chemical Neuroscience. 10, 6, p. 2939-2955 17 p.

Research output: Contribution to journalArticle

Neuralgia
Calcium Channels
Biological Products
Molecules
Electric potential
1 Citation (Scopus)

Annonalide and derivatives: Semisynthesis, cytotoxic activities and studies on interaction of annonalide with DNA

Marques, R. A., Gomes, A. O. C. V., de Brito, M. V., dos Santos, A. L. P., da Silva, G. S., de Lima, L. B., Nunes, F. M., de Mattos, M. C., de Oliveira, F. C. E., do Ó Pessoa, C., de Moraes, M. O., de Fátima, Â., Franco, L. L., Silva, M. D. M., Dantas, M. D. D. A., Santos, J. C. C., Figueiredo, I. M., da Silva-Júnior, E. F., de Aquino, T. M., de Araújo-Júnior, J. X. & 2 others, de Oliveira, M. C. F. & Gunatilaka, L., Feb 1 2018, In : Journal of Photochemistry and Photobiology B: Biology. 179, p. 156-166 11 p.

Research output: Contribution to journalArticle

deoxyribonucleic acid
DNA
Abietane Diterpenes
cancer
interactions