Mark "Marty" Pagel

  • 3055 Citations
  • 32 h-Index
1991 …2020

Research output per year

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Research Output

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Article
2020

Measuring Kidney Perfusion, pH, and Renal Clearance Consecutively Using MRI and Multispectral Optoacoustic Tomography

Minhas, A. S., Sharkey, J., Randtke, E. A., Murray, P., Wilm, B., Pagel, M. D. & Poptani, H., Jun 1 2020, In : Molecular Imaging and Biology. 22, 3, p. 494-503 10 p.

Research output: Contribution to journalArticle

2019

Calcium carbonate nanoparticles stimulate tumor metabolic reprogramming and modulate tumor metastasis

Som, A., Raliya, R., Paranandi, K., High, R. A., Reed, N., Beeman, S. C., Brandenburg, M., Sudlow, G., Prior, J. L., Akers, W., Mah-Som, A. Y., Habimana-Griffin, L., Garbow, J., Ippolito, J. E., Pagel, M. M., Biswas, P. & Achilefu, S., Jan 1 2019, In : Nanomedicine. 14, 2, p. 169-182 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Differentiating lung cancer and infection based on measurements of extracellular pH with acidoCEST MRI

Lindeman, L. R., Jones, K. M., High, R. A., Howison, C. M., Shubitz, L. F. & Pagel, M. D., Dec 1 2019, In : Scientific reports. 9, 1, 13002.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Differentiation of Myositis-Induced Models of Bacterial Infection and Inflammation with T2-Weighted, CEST, and DCE-MRI

Goldenberg, J. M., Berthusen, A. J., Cárdenas-Rodríguez, J. & Pagel, M. D., Sep 1 2019, In : Tomography (Ann Arbor, Mich.). 5, 3, p. 283-291 9 p.

Research output: Contribution to journalArticle

Open Access

Extracellular acidosis differentiates pancreatitis and pancreatic cancer in mouse models using acidoCEST MRI

High, R. A., Randtke, E. A., Jones, K. M., Lindeman, L. R., Ma, J. C., Zhang, S., LeRoux, L. G. & Pagel, M. D., Nov 2019, In : Neoplasia (United States). 21, 11, p. 1085-1090 6 p.

Research output: Contribution to journalArticle

Open Access

Machine learning improves classification of preclinical models of pancreatic cancer with chemical exchange saturation transfer MRI

Goldenberg, J. M., Cárdenas-Rodríguez, J. & Pagel, M. D., Jan 2019, In : Magnetic Resonance in Medicine. 81, 1, p. 594-601 8 p.

Research output: Contribution to journalArticle

Summary of Imaging in 2020: Visualizing the Future of Healthcare with MR Imaging

Corbin, B. A., Pollard, A. C., Allen, M. J. & Pagel, M. D., Apr 15 2019, In : Molecular Imaging and Biology. 21, 2, p. 193-199 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

A comparison of exogenous and endogenous CEST MRI methods for evaluating in vivo pH

Lindeman, L. R., Randtke, E. A., High, R. A., Jones, K. M., Howison, C. M. & Pagel, M. M., May 1 2018, In : Magnetic Resonance in Medicine. 79, 5, p. 2766-2772 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

A Comparison of Iron Oxide Particles and Silica Particles for Tracking Organ Recellularization

Kobes, J. E., Georgiev, G. I., Louis, A. V., Calderon, I. A., Yoshimaru, E. S., Klemm, L. M., Cromey, D. W., Khalpey, Z. I. & Pagel, M. M., Jul 20 2018, In : Molecular Imaging. 17

Research output: Contribution to journalArticle

A light-fluence-independent method for the quantitative analysis of dynamic contrast-enhanced multispectral optoacoustic tomography (DCE MSOT)

Hupple, C. W., Morscher, S., Burton, N. C., Pagel, M. D., McNally, L. R. & Cárdenas-Rodríguez, J., Jun 2018, In : Photoacoustics. 10, p. 54-64 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Characterization of D-maltose as a T2-exchange contrast agent for dynamic contrast-enhanced MRI

Goldenberg, J. M., Pagel, M. M. & Cárdenas-Rodríguez, J., Jan 1 2018, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

5 Scopus citations

Clinical applications of chemical exchange saturation transfer (CEST) MRI

Jones, K. M., Pollard, A. C. & Pagel, M. M., Jan 1 2018, In : Journal of Magnetic Resonance Imaging. 47, 1, p. 11-27 17 p.

Research output: Contribution to journalArticle

55 Scopus citations

Detection of Enzyme Activity and Inhibition during Studies in Solution, In Vitro and In Vivo with CatalyCEST MRI

Sinharay, S., Randtke, E. A., Howison, C. M., Ignatenko, N. A. & Pagel, M. D., Apr 1 2018, In : Molecular Imaging and Biology. 20, 2, p. 240-248 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Linearization improves the repeatability of quantitative dynamic contrast-enhanced MRI

Jones, K. M., Pagel, M. M. & Cárdenas-Rodríguez, J., Apr 1 2018, In : Magnetic Resonance Imaging. 47, p. 16-24 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Parallel accumulation of tumor hyaluronan, collagen, and other drivers of tumor progression

Li, X., Michael Shepard, H., Cowell, J. A., Zhao, C., Osgood, R. J., Rosengren, S., Blouw, B., Garrovillo, S. A., Pagel, M. M., Whatcott, C. J., Han, H., Von Hoff, D. D., Taverna, D. M., LaBarre, M. J., Maneval, D. C. & Thompson, C. B., Oct 1 2018, In : Clinical Cancer Research. 24, 19, p. 4798-4807 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Preliminary Results that Assess Metformin Treatment in a Preclinical Model of Pancreatic Cancer Using Simultaneous [18F]FDG PET and acidoCEST MRI

Goldenberg, J. M., Cárdenas-Rodríguez, J. & Pagel, M. M., Jan 26 2018, (Accepted/In press) In : Molecular Imaging and Biology. p. 1-9 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

Detecting in vivo urokinase plasminogen activator activity with a catalyCEST MRI contrast agent

Sinharay, S., Howison, C. M., Baker, A. F. & Pagel, M. D., Jul 2017, In : NMR in biomedicine. 30, 7, e3721.

Research output: Contribution to journalArticle

4 Scopus citations

Detection of DT-diaphorase Enzyme with a ParaCEST MRI Contrast Agent

Daryaei, I., Jones, K. M. & Pagel, M. M., May 11 2017, In : Chemistry - A European Journal. 23, 27, p. 6514-6517 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Imaging Lung Cancer by Using Chemical Exchange Saturation Transfer MRI With Retrospective Respiration Gating

Jones, K. M., Stuehm, C. A., Hsu, C. C., Kuo, P. H., Pagel, M. M. & Randtke, E. A., Dec 1 2017, In : Tomography (Ann Arbor, Mich.). 3, 4, p. 201-210 10 p.

Research output: Contribution to journalArticle

Open Access

Managers of Molecular Imaging Laboratories (MOMIL) Interest Group

Nickels, M. L. & Pagel, M. M., Mar 15 2017, (Accepted/In press) In : Molecular Imaging and Biology. p. 1-4 4 p.

Research output: Contribution to journalArticle

Noninvasive detection of enzyme activity in tumor models of human ovarian cancer using catalyCEST MRI

Sinharay, S., Randtke, E. A., Jones, K. M., Howison, C. M., Chambers, S. K., Kobayashi, H. & Pagel, M. D., May 2017, In : Magnetic Resonance in Medicine. 77, 5, p. 2005-2014 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016

A biomarker-responsive T2ex MRI contrast agent

Daryaei, I., Randtke, E. A. & Pagel, M. M., 2016, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

4 Scopus citations

A CatalyCEST MRI Contrast Agent that Can Simultaneously Detect Two Enzyme Activities

Fernández-Cuervo, G., Sinharay, S. & Pagel, M. D., Mar 2 2016, In : ChemBioChem. 17, 5, p. 383-387 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Advances in Magnetic Resonance Imaging Contrast Agents for Biomarker Detection

Sinharay, S. & Pagel, M. D., Jun 12 2016, In : Annual Review of Analytical Chemistry. 9, p. 95-115 21 p.

Research output: Contribution to journalArticle

35 Scopus citations

A single diamagnetic catalyCEST MRI contrast agent that detects cathepsin B enzyme activity by using a ratio of two CEST signals

Hingorani, D. V., Montano, L. A., Randtke, E. A., Lee, Y. S., Cárdenas-Rodríguez, J. & Pagel, M. D., Mar 1 2016, In : Contrast Media and Molecular Imaging. 11, 2, p. 130-138 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI

Akhenblit, P. J., Hanke, N. T., Gill, A., Persky, D. O., Howison, C. M., Pagel, M. M. & Baker, A. F., 2016, In : Molecular Imaging. 15

Research output: Contribution to journalArticle

10 Scopus citations

Clinical Translation of Tumor Acidosis Measurements with AcidoCEST MRI

Jones, K. M., Randtke, E. A., Yoshimaru, E. S., Howison, C. M., Chalasani, P., Klein, R. R., Chambers, S. K., Kuo, P. H. & Pagel, M. M., Nov 28 2016, (Accepted/In press) In : Molecular Imaging and Biology. p. 1-9 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Detection of Alkaline Phosphatase Enzyme Activity with a CatalyCEST MRI Biosensor

Daryaei, I., Mohammadebrahim Ghaffari, M., Jones, K. M. & Pagel, M. M., Jul 22 2016, In : ACS Sensors. 1, 7, p. 857-861 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Detection of Sulfatase Enzyme Activity with a CatalyCEST MRI Contrast Agent

Sinharay, S., Fernández-Cuervo, G., Acfalle, J. P. & Pagel, M. D., May 4 2016, In : Chemistry - A European Journal. 22, 19, p. 6491-6495 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Diamagnetic Imaging Agents with a Modular Chemical Design for Quantitative Detection of β-Galactosidase and β-Glucuronidase Activities with CatalyCEST MRI

Fernández-Cuervo, G., Tucker, K. A., Malm, S. W., Jones, K. M. & Pagel, M. M., Oct 19 2016, In : Bioconjugate Chemistry. 27, 10, p. 2549-2557 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Improved Treatment of Pancreatic Cancer With Drug Delivery Nanoparticles Loaded With a Novel AKT/PDK1 Inhibitor

Kobes, J. E., Daryaei, I., Howison, C. M., Bontrager, J. G., Sirianni, R. W., Meuillet, E. & Pagel, M. M., Feb 26 2016, (Accepted/In press) In : Pancreas.

Research output: Contribution to journalArticle

9 Scopus citations

Multislice CEST MRI improves the spatial assessment of tumor pH

Randtke, E. A., Granados, J. C., Howison, C. M., Pagel, M. M. & Cárdenas-Rodríguez, J., 2016, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

9 Scopus citations

QUESPOWR MRI: QUantification of Exchange as a function of Saturation Power On the Water Resonance

Randtke, E. A., Pagel, M. M. & Cárdenas-Rodríguez, J., Sep 1 2016, In : Journal of Magnetic Resonance. 270, p. 56-70 15 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

A comparison of iopromide and iopamidol, two acidoCEST MRI contrast media that measure tumor extracellular pH

Moon, B. F., Jones, K. M., Chen, L. Q., Liu, P., Randtke, E. A., Howison, C. M. & Pagel, M. M., Nov 1 2015, In : Contrast Media and Molecular Imaging. 10, 6, p. 446-455 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Assessment of carbonic anhydrase IX expression and extracellular pH in B-cell lymphoma cell line models

Chen, L. Q., Howison, C. M., Spier, C., Stopeck, A. T., Malm, S. W., Pagel, M. D. & Baker, A. F., May 1 2015, In : Leukemia and Lymphoma. 56, 5, p. 1432-1439 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Design and optimization of pulsed Chemical Exchange Saturation Transfer MRI using a multiobjective genetic algorithm

Yoshimaru, E. S., Randtke, E. A., Pagel, M. M. & Cárdenas-Rodríguez, J., Feb 26 2015, (Accepted/In press) In : Journal of Magnetic Resonance.

Research output: Contribution to journalArticle

6 Scopus citations

Diffusion MRI with Semi-Automated Segmentation Can Serve as a Restricted Predictive Biomarker of the Therapeutic Response of Liver Metastasis

Stephen, R. M., Jha, A. K., Roe, D. J., Trouard, T. P., Galons, J. P., Kupinski, M. A., Frey, G., Cui, H., Squire, S., Pagel, M. M., Rodriguez, J. J., Gillies, R. J. & Stopeck, A. T., Dec 1 2015, In : Magnetic Resonance Imaging. 33, 10, p. 1267-1273 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Evaluations of Tumor Acidosis Within In Vivo Tumor Models Using Parametric Maps Generated with AcidoCEST MRI

Chen, L. Q., Randtke, E. A., Jones, K. M., Moon, B. F., Howison, C. M. & Pagel, M. M., Jan 27 2015, In : Molecular Imaging and Biology. 17, 4, p. 488-496 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Measuring Extracellular pH in a Lung Fibrosis Model with acidoCEST MRI

Jones, K. M., Randtke, E. A., Howison, C. M., Cárdenas-Rodríguez, J., Sime, P. J., Kottmann, M. R. & Pagel, M. D., Jan 1 2015, In : Molecular Imaging and Biology. 17, 2, p. 177-184 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
8 Scopus citations
2014

Autocrine inhibition of the c-fms proto-oncogene reduces breast cancer bone metastasis assessed with in vivo dual-modality imaging

Jeffery, J. J., Lux, K., Vogel, J. S., Herrera, W. D., Greco, S., Woo, H. H., AbuShahin, N., Pagel, M. D. & Chambers, S. K., Apr 2014, In : Experimental Biology and Medicine. 239, 4, p. 404-413 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Comparison of analytical and numerical analysis of the reference region model for DCE-MRI

Lee, J., Cárdenas-Rodríguez, J., Pagel, M. D., Platt, S., Kent, M. & Zhao, Q., Sep 2014, In : Magnetic Resonance Imaging. 32, 7, p. 845-853 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Detection of in vivo enzyme activity with CatalyCEST MRI

Yoo, B., Sheth, V. R., Howison, C. M., Douglas, M. J. K., Pineda, C. T., Maine, E. A., Baker, A. F. & Pagel, M. D., Mar 2014, In : Magnetic Resonance in Medicine. 71, 3, p. 1221-1230 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Evaluations of extracellular PH within in vivo tumors using acidocest MRI

Chen, L. Q., Howison, C. M., Jeffery, J. J., Robey, I. F., Kuo, P. H. & Pagel, M. D., Nov 1 2014, In : Magnetic Resonance in Medicine. 72, 5, p. 1408-1417 10 p.

Research output: Contribution to journalArticle

96 Scopus citations

Nanoparticle delivery of an akt/pdk1 inhibitor improves the therapeutic effect in pancreatic cancer

Lucero-Acuña, A., Jeffery, J. J., Abril, E. R., Nagle, R. B., Guzman, R., Pagel, M. D. & Meuillet, E. J., Jan 1 2014, In : International journal of nanomedicine. 9, 1, p. 5653-5665 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Reproducibility of magnetic resonance perfusion imaging

Zhang, X., Pagel, M. D., Baker, A. F. & Gillies, R. J., Feb 25 2014, In : PloS one. 9, 2, e89797.

Research output: Contribution to journalArticle

14 Scopus citations

The Hanes-Woolf linear QUESP method improves the measurements of fast chemical exchange rates with CEST MRI

Randtke, E. A., Chen, L. Q., Corrales, L. R. & Pagel, M. D., Apr 2014, In : Magnetic Resonance in Medicine. 71, 4, p. 1603-1612 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

The reciprocal linear QUEST analysis method facilitates the measurements of chemical exchange rates with CEST MRI

Randtke, E. A., Chen, L. Q. & Pagel, M. D., Jan 1 2014, In : Contrast Media and Molecular Imaging. 9, 3, p. 252-258 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2013

A catalyCEST MRI contrast agent that detects the enzyme-catalyzed creation of a covalent bond

Hingorani, D. V., Randtke, E. A. & Pagel, M. D., May 1 2013, In : Journal of the American Chemical Society. 135, 17, p. 6396-6398 3 p.

Research output: Contribution to journalArticle

47 Scopus citations

A linear algorithm of the reference region model for DCE-MRI is robust and relaxes requirements for temporal resolution

Cárdenas-Rodríguez, J., Howison, C. M. & Pagel, M. D., May 1 2013, In : Magnetic Resonance Imaging. 31, 4, p. 497-507 11 p.

Research output: Contribution to journalArticle

27 Scopus citations