• 746 Citations
  • 16 h-Index
20062018
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 2006 2018

  • 746 Citations
  • 16 h-Index
  • 36 Article
  • 1 Chapter

A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B)

François-Moutal, L. , Jahanbakhsh, S. , Nelson, A. D. L. , Ray, D. , Scott, D. D. , Hennefarth, M. R. , Moutal, A. , Perez-Miller, S. , Ambrose, A. J. , Al-Shamari, A. , Coursodon, P. , Meechoovet, B. , Reiman, R. , Lyons, E. , Beilstein, M. , Chapman, E. , Morris, Q. D. , Van Keuren-Jensen, K. , Hughes, T. R. , Khanna, R. & 4 others Koehler, C., Jen, J., Gokhale, V. & Khanna, M., Jan 1 2018, (Accepted/In press) In : ACS Chemical Biology.

Research output: Contribution to journalArticle

RNA
Thermophoresis
Zebrafish
Molecules
Exosome Multienzyme Ribonuclease Complex

Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels

François-Moutal, L., Scott, D. D., Perez-Miller, S., Gokhale, V., Khanna, M. & Khanna, R., Jan 1 2018, (Accepted/In press) In : Channels.

Research output: Contribution to journalArticle

Chemical shift
Modulation
Sumoylation
Drug Discovery
Pain
5 Citations

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function

Dustrude, E. T., Perez-Miller, S., François-Moutal, L., Moutal, A., Khanna, M. & Khanna, R., Mar 24 2017, (Accepted/In press) In : Channels. p. 1-13 13 p.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin
NAV1.7 Voltage-Gated Sodium Channel
Lysine
Monomers
4 Citations

CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide

Moutal, A., Yang, X., Li, W., Gilbraith, K. B., Luo, S., Cai, S., François-Moutal, L., Chew, L. A., Yeon, S. K., Bellampalli, S. S., Qu, C., Xie, J. Y., Ibrahim, M. M., Khanna, M., Park, K. D., Porreca, F. & Khanna, R., Jan 1 2017, In : Pain. 158, 12, p. 2301-2319 19 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Neurofibromatosis 1 Genes
Neurofibromatosis 1
Neurofibromin 1
Pain
3 Citations

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides

Moutal, A., Li, W., Wang, Y., Ju, W., Luo, S., Cai, S., François-Moutal, L., Perez-Miller, S., Hu, J., Dustrude, E. T., Vanderah, T. W., Gokhale, V., Khanna, M. & Khanna, R., 2017, (Accepted/In press) In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

Neuralgia
Calcium
Pain
Peptides
Amino Acids