• 791 Citations
  • 17 h-Index
20062019
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 1 Similar Profiles
Neuralgia Medicine & Life Sciences
Sumoylation Medicine & Life Sciences
Peptide Aptamers Medicine & Life Sciences
Peptides Medicine & Life Sciences
N-Type Calcium Channels Medicine & Life Sciences
Calcium Channels Medicine & Life Sciences
Proteins Medicine & Life Sciences
Aldehyde Dehydrogenase Medicine & Life Sciences

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Research Output 2006 2019

  • 791 Citations
  • 17 h-Index
  • 38 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Letter

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels

Bellampalli, S. S., Ji, Y., Moutal, A., Cai, S., Wijeratne, E. M. K., Gandini, M. A., Yu, J., Chefdeville, A., Dorame, A., Chew, L. A., Madura, C. L., Luo, S., Molnar, G., Khanna, M., Streicher, J. M., Zamponi, G. W., Gunatilaka, L. & Khanna, R., Jan 1 2019, In : Pain. 160, 1, p. 117-135 19 p.

Research output: Contribution to journalArticle

Hyptis
T-Type Calcium Channels
N-Type Calcium Channels
Lavandula
Peripheral Nervous System Diseases

A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B)

François-Moutal, L., Jahanbakhsh, S., Nelson, A. D. L., Ray, D., Scott, D. D., Hennefarth, M. R., Moutal, A., Perez-Miller, S., Ambrose, A. J., Al-Shamari, A., Coursodon, P., Meechoovet, B., Reiman, R., Lyons, E. H., Beilstein, M. A., Chapman, E., Morris, Q. D., Van Keuren-Jensen, K., Hughes, T. R., Khanna, R. & 4 othersKoehler, C., Jen, J., Gokhale, V. & Khanna, M., Jan 1 2018, (Accepted/In press) In : ACS Chemical Biology.

Research output: Contribution to journalArticle

RNA
Thermophoresis
Zebrafish
Molecules
Exosome Multienzyme Ribonuclease Complex
5 Citations

Blocking CRMP2 SUMOylation reverses neuropathic pain

Moutal, A., Dustrude, E. T., Largent-Milnes, T. M., Vanderah, T. W., Khanna, M. & Khanna, R., Nov 1 2018, In : Molecular Psychiatry. 23, 11, p. 2119-2121 3 p.

Research output: Contribution to journalLetter

Sumoylation
Neuralgia
1 Citations

Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels

François-Moutal, L., Scott, D. D., Perez-Miller, S., Gokhale, V., Khanna, M. & Khanna, R., Jan 1 2018, (Accepted/In press) In : Channels.

Research output: Contribution to journalArticle

Chemical shift
Modulation
Sumoylation
Drug Discovery
Pain
4 Citations

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

François-Moutal, L., Dustrude, E. T., Wang, Y., Brustovetsky, T., Dorame, A., Ju, W., Moutal, A., Perez-Miller, S., Brustovetsky, N., Gokhale, V., Khanna, M. & Khanna, R., Oct 1 2018, In : Pain. 159, 10, p. 2115-2127 13 p.

Research output: Contribution to journalArticle

Sumoylation
Neuralgia
Ubiquitin
Enzymes
Peptides