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Cryptosporidium parvum Medicine & Life Sciences
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Projects 1990 1999

IMMUNOTHERAPY OF CRYPTOSPORIDIOSIS USING MONOCLONALS

Sterling, C. R., Riggs, M. W., Cama, V., Enriquez, F. J. & Perryman, L.

National Institutes of Health

7/1/905/31/99

Project: Research projectResearch Project--Cooperative Agreements, Research Program--Cooperative Agreements

Merozoites
Cryptosporidiosis
Monoclonal Antibodies
Infection
Cryptosporidium parvum

Research Output 1987 2017

  • 1035 Citations
  • 18 h-Index
  • 43 Article

5-Aminopyrazole-4-carboxamide-based compounds prevent the growth of Cryptosporidium parvum

Huang, W., Choi, R., Hulverson, M. A., Zhang, Z., McCloskey, M. C., Schaefer, D. A., Whitman, G. R., Barrett, L. K., Vidadala, R. S. R., Riggs, M. W., Maly, D. J., Van Voorhis, W. C., Ojo, K. K. & Fan, E. Aug 1 2017 In : Antimicrobial Agents and Chemotherapy. 61, 8, e00020

Research output: Research - peer-reviewArticle

Cryptosporidium parvum
Growth
5-aminopyrazole
calcium-dependent protein kinase
Cryptosporidiosis
1 Citations

Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis

Hulverson, M. A. , Choi, R. , Arnold, S. L. M. , Schaefer, D. A. , Hemphill, A. , McCloskey, M. C. , Betzer, D. P. , Müller, J. , Vidadala, R. S. R. , Whitman, G. R. , Rivas, K. L. , Barrett, L. K. , Hackman, R. C. , Love, M. S. , McNamara, C. W. , Shaughnessy, T. K. , Kondratiuk, A. , Kurnick, M. , Banfor, P. N. , Lynch, J. J. & 6 others Freiberg, G. M., Kempf, D. J., Maly, D. J., Riggs, M. W., Ojo, K. K. & Van Voorhis, W. C. 2017 (Accepted/In press) In : International Journal for Parasitology.

Research output: Research - peer-reviewArticle

Cryptosporidiosis
Phosphotransferases
Therapeutics
Safety
Lead
6 Citations

Bumped-kinase inhibitors for cryptosporidiosis therapy

Hulverson, M. A., Vinayak, S., Choi, R., Schaefer, D. A., Castellanos-Gonzalez, A., Vidadala, R. S. R., Brooks, C. F., Herbert, G. T., Betzer, D. P., Whitman, G. R., Sparks, H. N., Arnold, S. L. M., Rivas, K. L., Barrett, L. K., White, A. C., Maly, D. J., Riggs, M. W., Striepen, B., Van Voorhis, W. C. & Ojo, K. K. 2017 In : Journal of Infectious Diseases. 215, 8, p. 1275-1284 10 p.

Research output: Research - peer-reviewArticle

Cryptosporidiosis
Phosphotransferases
Therapeutics
Cryptosporidium parvum
In Vitro Techniques
2 Citations

Extended-spectrum antiprotozoal bumped kinase inhibitors: A review

Van Voorhis, W. C., Doggett, J. S., Parsons, M., Hulverson, M. A., Choi, R., Arnold, S., Riggs, M. W., Hemphill, A., Howe, D. K., Mealey, R. H., Lau, A. O. T., Merritt, E. A., Maly, D. J., Fan, E. & Ojo, K. K. 2017 (Accepted/In press) In : Experimental Parasitology.

Research output: Research - peer-reviewArticle

Parasites
Phosphotransferases
Protein Kinases
Parasitic Diseases
Life Cycle Stages
2 Citations

Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection

Arnold, S. L. M., Choi, R., Hulverson, M. A., Schaefer, D. A., Vinayak, S., Vidadala, R. S. R., McCloskey, M. C., Whitman, G. R., Huang, W., Barrett, L. K., Ojo, K. K., Fan, E., Maly, D. J., Riggs, M. W., Striepen, B. & Van Voorhis, W. C. Jul 1 2017 In : Journal of Infectious Diseases. 216, 1, p. 55-63 9 p.

Research output: Research - peer-reviewArticle

Cryptosporidium
Phosphotransferases
Pharmacokinetics
Infection
Pharmaceutical Preparations